We're living in a present where a large amount of physical products are being transformed into software-based services. It's not just miniaturization. It's a paradigm shift: from atoms to bits.
This trend is accelerating at a tremendous speed, and the dematerialization of physical technologies, ubiquitous connectivity and seamlessly distributed sensor networks are driving humanity into a future where we will be immersed into a sensing environment.
What are the opportunities? Which technologies are already available and which are on the edge of disruption?
Dimagi, Inc. is a for- profit social enterprise based in Cambridge Founded in 2002 By MEDIA LAB ( MIT )
Dimagi became a certified B corporation in 2008 and an incorporated benefit corporation in 2012
The company designs clinical interfaces, health information systems, and mobile technologies to perform patient-level disease management, clinical decision support, and health system monitoring
Dimagi, Inc. is an award-winning, socially conscious technology company that develops scalable ICT solutions for low-resource settings
Speakers: Kian Sanaii, CEO, Independa, Inc.; David Schie, CEO , Linear Dimensions; Shireen Yates, CEO, Co-Founder, 6SensorLabs
The Digital Health Summit, produced by Living in Digital Times, convenes one of the broadest spectrum of health care and technology audiences in the world. The Summit features innovations and advancements in genomics, diagnostics, wearables, telehealth and more in the mobile health market which is expected to reach $26 billion by 2017. This is a must see event each year that takes place at the International Consumer Electronics Show (CES) in Las Vegas.
Website: Http://www.digitalhealthsummit.com
Twitter: http://www.twitter.com/dhsummit
Hashtags: #digitalhealthces #ces2016
Photos: https://www.flickr.com/digitalhealthsummit
Dimagi, Inc. is a for- profit social enterprise based in Cambridge Founded in 2002 By MEDIA LAB ( MIT )
Dimagi became a certified B corporation in 2008 and an incorporated benefit corporation in 2012
The company designs clinical interfaces, health information systems, and mobile technologies to perform patient-level disease management, clinical decision support, and health system monitoring
Dimagi, Inc. is an award-winning, socially conscious technology company that develops scalable ICT solutions for low-resource settings
Speakers: Kian Sanaii, CEO, Independa, Inc.; David Schie, CEO , Linear Dimensions; Shireen Yates, CEO, Co-Founder, 6SensorLabs
The Digital Health Summit, produced by Living in Digital Times, convenes one of the broadest spectrum of health care and technology audiences in the world. The Summit features innovations and advancements in genomics, diagnostics, wearables, telehealth and more in the mobile health market which is expected to reach $26 billion by 2017. This is a must see event each year that takes place at the International Consumer Electronics Show (CES) in Las Vegas.
Website: Http://www.digitalhealthsummit.com
Twitter: http://www.twitter.com/dhsummit
Hashtags: #digitalhealthces #ces2016
Photos: https://www.flickr.com/digitalhealthsummit
Nathan Downing - ECO 20: Empowering care homes through innovation and improve...Innovation Agency
Presentation by Nathan Downing, Associate - Business Strategy & Service Transformation, TSA at ECO 20: Empowering care homes through innovation and improvement on Wednesday 25 September at Liverpool Hotel Hilton.
HXR 2016: Improving Insurance Member Experiences -Christopher NeuharthHxRefactored
This section of the agenda will feature leaders in innovation, customer experience, and design within the health insurance space. Each panelist will present the current state of experience at their organization, what successes they have seen, what situations they have learned from, and what their challenges and obstacles are, and where they would like to see things head in the future. Then Amy Cueva will guide the group in a discussion around strategy, measurement, culture change, and other important topics relevant to delivering phenomenal experiences.
HxRefactored 2015: Drew Schiller "Beyond the Bracelet"HxRefactored
Drew Schiller, Co-founder & CTO of Validic discusses changes in healthcare as a result of the wearable movement which enables patients to take a more active role in their own healthcare.
The future of healthcare: when mobile disappearsMatteo Penzo
In today’s digital world, mobile devices are the powerful bridges between a connected ecosystem of healthcare professionals, caregivers and patients. New developments in big data, wearable sensors and the application of social layers are shifting an industry that used to focus on curing diseases to one that emphasizes health and wellness. But the mass adoption of connected healthcare will only happen when solutions are designed to be intuitive and technologies are forgotten. The future of healthcare will happen when mobile disappears into the background, placing the patient in the center and in control of their lives.
Nathan Downing - ECO 20: Empowering care homes through innovation and improve...Innovation Agency
Presentation by Nathan Downing, Associate - Business Strategy & Service Transformation, TSA at ECO 20: Empowering care homes through innovation and improvement on Wednesday 25 September at Liverpool Hotel Hilton.
HXR 2016: Improving Insurance Member Experiences -Christopher NeuharthHxRefactored
This section of the agenda will feature leaders in innovation, customer experience, and design within the health insurance space. Each panelist will present the current state of experience at their organization, what successes they have seen, what situations they have learned from, and what their challenges and obstacles are, and where they would like to see things head in the future. Then Amy Cueva will guide the group in a discussion around strategy, measurement, culture change, and other important topics relevant to delivering phenomenal experiences.
HxRefactored 2015: Drew Schiller "Beyond the Bracelet"HxRefactored
Drew Schiller, Co-founder & CTO of Validic discusses changes in healthcare as a result of the wearable movement which enables patients to take a more active role in their own healthcare.
The future of healthcare: when mobile disappearsMatteo Penzo
In today’s digital world, mobile devices are the powerful bridges between a connected ecosystem of healthcare professionals, caregivers and patients. New developments in big data, wearable sensors and the application of social layers are shifting an industry that used to focus on curing diseases to one that emphasizes health and wellness. But the mass adoption of connected healthcare will only happen when solutions are designed to be intuitive and technologies are forgotten. The future of healthcare will happen when mobile disappears into the background, placing the patient in the center and in control of their lives.
2023 and Beyond-Healthcare App Development Trends You Can’t Ignore.pdfTechugo
In the rapidly evolving world of healthcare, mobile app development has emerged as a game-changer. With the pandemic and the increasing use of smartphones, the demand for healthcare apps is only expected to rise in the coming years. In this context, it is important for healthcare organizations to stay updated with the latest trends in app development to ensure they are providing the best possible care for their patients.
با گسترش فناوری اطلاعات و سرویس های مختلفی امروزه در زندگی انسان ها ارائه می شود حوزه سلامت و درمان هم بی بهره از این گسترش فناوری نبوده و در صورتی که سیاستمداران و برنامه ریزان کشور بتوانند از ظرفیت های ترکیب دانش پزشکی و فناوری اطلاعات بهره ببرند شاید با وجود افزایش جمعیت کهنسال و نیاز به رسیدگی های خاصی که در این قشر احساس می شود بتوان در کاهش هزینه های درمان گامی برداشت
Emerald Venture Partners Presentation - HIT September 2023KC Digital Drive
These slides were presented at the October 2023 meeting of the KC Digital Drive Health Innovation Team.
This presentation will focus on how the incorporation of technology in healthcare is essential to driving an integrated care model –one which is holistic, person-centered, and shows clear communication between the different specialties, providers, and levels of care. The explosive growth and adoption of virtual consultations, remote monitoring, mobile health, digital therapeutics, artificial intelligence/machine learning has gained significant support from doctors and patients alike. The role and importance of digital health in integrated care has never been greater. Understanding this field is critical as we work towards more integrated models of care – the validation and adoption of medical advances, using critical insights from health information, and optimizing specialists and providers for person-centered, high-quality, cost-effective care.
Mobile health apps bring about improvement
in overall patient satisfaction by fostering a
connected system of care. The overall cost of care
is also reduced. mobile health apps
provide D2C connect which empowers
the end users with customised information,
advice and also helps drive qualified
referrals to the providers. It helps
increase the overall patient satisfaction
through follow ups and connected care
all while reducing the overall cost of care.
Unfortunately, most of today’s mHealth
applications are limited in their ability to
both access and share information because
the data is sitting in silos, typically
locked away in disparate, proprietary, redundant systems that are hard to integrate.
After the successful launch of our Doctor on Call service, HealthFore intends to launch continuous---> collaborative--- >connected point of care mechanisms.
The Potential of Digital and Remote Care Post-Pandemic-Iain Ansell, Team Cons...marcus evans Network
Ahead of the marcus evans Medical Device Manufacturing Summit 2021, Iain Ansell discusses the future of digital health and how manufacturers can ensure connected devices are user centric
Design and implementation of instructional 3D Web-based interactive medical d...Pubrica
Top 3D Animation Services Companies in India virtual worlds and computer simulations are examples of these, which can help healthcare professionals improve their training by giving them hands-on experience in virtual surroundings.
Learn More : https://pubrica.com/services/scientific-communication/
Reference: https://bit.ly/3r1iP9t
Why Pubrica:
When you order our services, we promise you the following – Plagiarism free | always on Time | 24*7 customer support | Written to international Standard | Unlimited Revisions support | Medical writing Expert | Publication Support | Bio statistical experts | High-quality Subject Matter Experts.
Contact us:
Web: https://pubrica.com/
Blog: https://pubrica.com/academy/
Email: sales@pubrica.com
WhatsApp : +91 9884350006
United Kingdom: +44-1618186353
The Ultimate Guide to Healthcare App Development.pdfLucy Zeniffer
Planning to build a healthcare application? Here is your expert’s guide on steps to build a healthcare app, including types, features, and benefits of healthcare applications.
Design and implementation of instructional 3D Web-based interactive medical d...Pubrica
Top 3D Animation Services Companies in India virtual worlds and computer simulations are examples of these, which can help healthcare professionals improve their training by giving them hands-on experience in virtual surroundings.
Learn More : https://pubrica.com/services/scientific-communication/
Reference: https://bit.ly/3r1iP9t
Why Pubrica:
When you order our services, we promise you the following – Plagiarism free | always on Time | 24*7 customer support | Written to international Standard | Unlimited Revisions support | Medical writing Expert | Publication Support | Bio statistical experts | High-quality Subject Matter Experts.
Contact us:
Web: https://pubrica.com/
Blog: https://pubrica.com/academy/
Email: sales@pubrica.com
WhatsApp : +91 9884350006
United Kingdom: +44-1618186353
Overcoming Cloud-Based Mobility Challenges in HealthcareAnyPresence
April Sage of Online Tech and Rich Mendis of AnyPresence review the common challenges associated with mobile enablement, and introduced the new technologies that are empowering healthcare providers to securely engage their patients and practitioners through the mobile channel.
M1. What does the digitization of socio-health services meanLuis Gómez Martinena
Learn about:
- The meaning of digitalization and its application to socio-health and care sectors.
- The advantages of digitalization.
- The main obstacles and barriers, with recommendations to overcome them.
- What digital skills are. Test your digital skills .
Creating a telemedicine app requires a combination of technical expertise, design skills and a deep understanding of the healthcare industry. The process starts with defining the app's purpose and identifying its target users. The next step is to create a detailed plan that outlines the app's features, functionalities and user interface. It's important to consider the security and privacy of patient data, as well as the regulations surrounding telemedicine. Once the plan is in place, a team of developers and designers can start building the app using the latest technologies and programming languages. Testing and quality assurance are crucial steps in the process, as they ensure the app is functional and user-friendly. Finally, the app needs to be deployed and marketed to reach its intended audience. With the right team and approach, creating a telemedicine app can greatly improve access to healthcare and help connect patients with healthcare providers in a convenient and efficient manner.
7 Reasons why Companies & Government should invest in Digital TransformationIsmail Sayeed
Early adoption of digital solutions to provide services, whether health related or not, allows organisations to be ready for future user demands. The large pool of data on patterns of service/product consumption, feedback and possible future behaviour (extracted from data analytics) can guide strategic decisions on what to invest in and for whom.
Digital healthcare innovation was needed decades ago, with or without a global health emergency. Other industries with complex systems have rapidly adopted digital transformation; such as logistics networks, taxation, commerce and others
- except healthcare.
A company that is already accustomed to some form of digital-based communication and operations (as much as possible) are the ones most able to survive and thrive in these circumstances.
A government body that can still function and serve remotely and digitally is the most ideal form of democracy. An organisation with remote workers, paperless reporting, established telecommunications through all chains of command are really agile in its truest form.
I had predicted 2 years ago that digital healthcare solutions would be the dominant narrative for the emerging middle class of many developing countries in Asia.
it is time for the global industry to transform itself to the new reality.
Now.
Digital technology advancements like Internet of Things (IoT)
* Wearable technologies
* Blockchain
* Robotics
* Big data
*Advanced analytics are changing consumer perceptions
The connected world brings many opportunities to healthcare, the question is how do we unlock them?
With the increase in chronic health conditions, and pressure on health services - driven by ageing populations and post-recessionary healthcare budgets - there has never been a better time to leverage the benefits of connected technology.
But with so many possibilities open to healthcare businesses across hardware devices, software applications and operating systems, it’s difficult to know where to focus to create the most value.
This paper highlights the opportunity and details the principles and journey to unlock it.
Future of Digital Healthcare on Cloud .pdfayushiqss
Healthcare has been an integral part of the discussion and a transformative force towards innovation. With increasing advancements and awareness, people are becoming more conscious about their choices, what they eat, and where and how to get the best treatment facilities. This brings the need to provide the best healthcare services, disease detection, and the right treatment, with the best tools and hospital staff. The internet has played a significant role in serving such kinds of top-notch consumer needs. One of these internets of things is Cloud Technology. Let’s look at cloud computing in healthcare, models of cloud computing and how it has transformed the digital healthcare sector.
Top 10 Mobile Healthcare App Development Trends 2022.pdfGroovy Web
With the support of technology and advancement, the healthcare industry is also growing rapidly just like other industries. The arrival of appearing app trends
Similar to The future of technology: seamless. (20)
In this deck I explore how design can improve products and industrial processes showing how starting from a radical change in the approach to business, any company could improve not only their own products, but can literally create new needs in their customers and, at the end, new markets and new business potential.
What are the ingredients behind frog approach to product/service development? We spent a morning chatting with the start-ups at Talent Garden in Milan in a session on how these could be applied to the lean startup world.
The future of healthcare: a seamless integration of technology into the patie...Matteo Penzo
The healthcare world is evolving: the traditional provider-patient relationship is shifting towards a more complex system in which caregivers and patients are active part of the health path.
The shifting of healthcare business models and ubiquitous connectivity are changing the way technology is perceived in most healthcare systems: we are moving from a world where technology is visible and perceived as a must have, to a world where technology will be ubiquitous and transparent to the patients.
CHALLENGES FOR DEVELOPERS IN A MULTI-DIMENSIONAL/MULTI-SENSUAL DEVICES SCENARIOMatteo Penzo
The rise of the smartphones completely changed the way we interact with technology and is shaping the very way we conduct our lives. But devices are still limited by the technologies available: what is going to be the market scenario wheninteraction surfaces will become_ubiquitous_multi-dimensional and multi-sensual? What are going to be the challenges for developers? What new possibilities created by human body control over the content are going to lead to?
How to run your business through Second LifeMatteo Penzo
A Slideshare adapted version of my speech at "achieving real business growth through Second Life" conference in London.
In these slides I depict how the Gabetti Group took its real world business (real estate) and moved it successfully to Second Life.
Gabetti on Second Life: strategy, results and backstageMatteo Penzo
A broad view of the presence of Gabetti Property Solutions, one of the biggest italian real estate companies, in Second Life. Slides by Rita Tornari and Matteo Penzo.
Mobup is a mobile uploader to Flickr cabale of automatic geotagging of the photos. This presentation has been given at the DUEpuntoZERO (2.0) conference in Turin in October 2006.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
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NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
30. “Soon, perhaps, it will be impossible
to tell where the humans end, and
the machines begin” Maureen McHugh
31. Smartphones are the enablers of
seamless integration of technology in
our lives and behaviors.
32. Services based on the aggregation
of data coming from multiple
nodes.
33. Services based on the aggregation
of data coming from multiple
nodes.
Services based on the aggregation
of data coming from multiple
sensors.
34. Services based on the aggregation
of data coming from multiple
nodes.
Services based on the aggregation
of data coming from multiple
sensors.
Services based on the lowering of
the adoption barriers.
37. Based on a new patient-centered healthcare paradigm, it
fosters a collaborative relationship between the patient,
providers and social networks to improve health outcomes
and help achieve lifestyle goals.
frog Connected Care Solution
38. Create Meaning from Data
1. 2. 3.
Making it part of
a conversation
Connecting it
to daily life
Associating it
with shared goals
40. An Intimate
Shared Care
Network
frog CCS leverages an
intimate social network
within the application to
offer support through
accountability and
encouragement and to
nudge the patient to stick
to the care plan with
prescribed activities.
41. On the patient application, the collected data are
interpreted by the Virtual Coach who provides in-
context and actionable suggestions for:
•Setting progressive targets tailored to user
needs,
•Supporting long-term behavior evolution
•Providing a contact link to receive direct support
during critical events
Interpretation
42. 42
The future is already
HERE.
It’s just not very evenly
distributed.
William Gibson