The brain, located within the cranium, is suspended in cerebro-spinal fluid and surrounded by membranes, controlling both voluntary and involuntary body functions. It consists of two hemispheres with specific areas for distinct functions, including the cerebrum for complex activities, the cerebellum for balance, and the medulla oblongata for automatic processes. The spinal cord connects the brain to the body through peripheral nerves for voluntary actions and the autonomic system for involuntary functions.