Team graham receptors-pharm
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This document discusses the basics of pharmacodynamics. It begins by introducing receptors, agonists, and antagonists. It then defines receptors as binding sites on cells that produce responses to chemicals like drugs. Agonists are chemicals that bind to receptors and activate a response, either increasing or decreasing cell activity. Antagonists bind to receptors to prevent activity. The document provides examples of agonists and antagonists, and demonstrates their actions through diagrams. It explains the importance of understanding pharmacodynamics for nurses to predict patient responses, select appropriate drugs, assess therapy effectiveness, and keep patients safe.
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Team graham receptors-pharm
- 1. WEIRD SCIENCE Receptors Agonists Antagonists
- 2. STARRING… Michele Baldwin Lindsey Graham
- 3. STARRING… Sarah Heiskell Natalie Wiens
- 4. PHARMACODYNAMICS • What drugs do to the body • How they do it • Integrated process that involves receptors, agonists, and antagonists
- 5. WHAT IS A RECEPTOR??? A macromolecule on the cell surface or in the cytoplasm A specific binding site for a chemical, such as a drug or hormone, that produces a response in the cell Responses include stimulating, depressing, or blocking the action
- 6. ALKA SELTZER EXPERIMENT (TO DEMONSTRATE ACTIVITY) A B
- 7. WHAT IS AN AGONIST??? Any chemical, such as a drug or hormone, that binds to the RECEPTOR on the cell, causing the cell to activate a response. The response may cause the activity of the cell to increase or decrease. Example: Norepinephrine attaches to receptors on the heart, causing the rate to increase. Example: Acetylcholine attaches to receptors on the heart, causing the rate to decrease. Photo http://www.mc.uky.edu/pharmacology/instruction/pha824mp/pha824mp.html
- 9. WHAT IS AN ANTAGONIST??? Any chemical, such as a drug or hormone, that binds to a RECEPTOR on the cell, to prevent activity Aka inhibitors Example: beta blockers used to treat high blood pressure Blocks signals from the sympathetic system to decrease heart rate and contractions. Photo: http://www.mc.uky.edu/pharmacology/instruction/pha824mp/pha824mp.h
- 11. WHY DO WE NEED TO KNOW THIS? By understanding pharmacodynamics, nurses Can predict the patient’s response to the drug Assists with proper drug selection Assess the therapy effectiveness-successful or unsuccessful Keeps patient safe
- 12. REFERENCES http://www.wisegeek.com/what-are-receptor- agonists.htm Silverthorn, Dee Unglaub, Ph. D. (2010) Human Physiology, An Integrated Approach, 5th ed. San Francisco, CA: Pearson. http://www. Merckmanuals.com/professional/ clinical_pharmacology/pharmacodynamics/drug- receptor_interactions.html http://www.en. Wikipedia.org/wiki/Receptor_(biochemistry)
- 13. GIRLS JUST WANT TO HAVE FUN IN NURSING SCHOOL!!!