My keynote for the Innochem Group in Bragança, Portugal. Oct, 13, 2016. Innochem is a group of 20 researchers from Portugal, France, Germany and Poland, in the field of Chemical Engineering.
24. The comparison of the genomes
from various species is one of the
most fundamental and powerful
technique in molecular Biology.
It helps us to decipher our DNA
and identify new genes.
25. Though it may appear to be
just a game, Phylo is actually
a framework for harnessing
the computing power of
mankind to solve the Multiple
Sequence Alignment problem.
26. Traditionally, multiple sequence
alignment algorithms use
computationally complex heuristics to
align the sequences.
Unfortunately, the use of heuristics
do not guarantee global optimization
as it would be prohibitively
computationally expensive to achieve
an optimal alignment.
27. Humans have evolved to recognize
patterns and solve visual problems
efficiently.
By abstracting multiple sequence
alignment to manipulating patterns
consisting of coloured shapes, Phylo
have adapted the problem to benefit
from human capabilities.
29. Support for education with
students and instructors areas
An open crowd-computing
plateform
Mobile versions
Independent language, players all
around the world
30. Phylo Expert Edition
Large puzzles of more than 300 bricks
Collaborate and improve solutions of
other players
Edit ancestor sequences
Store any intermediate configuration
during your game
31. btw, Pedro, thank you for
the help with this nucleotide
the Holoprosencephaly-9 is very
important to brain diseases
36. Folding proteins is a huge
computer science problem.
Even though proteins are just
a long chain of amino acids,
they don't like to stay
stretched out in a straight
line. The protein folds up to
make a compact blob.
37. This structure specifies the
function of the protein.
Since proteins are part of so
many diseases, they can also be
part of the cure.
Players can design brand new
proteins that could helpprevent
or treat important diseases.
38. One more time, the
processing cost for
achieving this is very high.
But humans can do it
like playing ;-)
42. Netflix had problems with your
recommendation system, Cinematch.
So, they rule an open competition
with 1 million dollars prize for the
best improvements.
They provided a training data set
of 100,480,507 ratings that 480,189
users gave to 17,770 movies.
50. With Goo gle Image Labeller,
everyday thousands of
players indexed for Goo gle
Images (2006-2013)
Today is no longer a game,
is something like “Help
Goo gle”
52. But not only working lives humanity
We need some entertainment too
53. Do you want to:
hunt the bad guys?
investigate a crime scene?
gather evidence?
take it to the lab?
use the lab gadgets?
uncover the truth?
work with Gim Grisson and his crew?
60. This approach uses
differences in abilities and
alternative costs between
humans and computer
agents to achieve symbiotic
human-computer interaction.
61. Usually, a human employs a
computer[2]
to solve a problem:
a human provides a
formalized problem
description and an algorithm
to a computer, and receives a
solution to interpret.
62. Human-based computation
frequently reverses the roles:
the computer asks a person
or a large group of people to
solve a problem, then collects,
interprets, and integrates
their solutions.
63. But, you need to convince
people to use your
system, so…….