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Hofstra Northwell School of Medicine
Hofstra Northwell School of Medicine

TMA

Health & Medicine
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HSCT related TMA Elevated BP AKI + proteinuria Hemolysis( LDH, haptoglobin) Anemia Thromobocytopenia Causes Treatment Small vessels, big trouble in the kidney and beyond: hematopoietic stem cell transplantation -associated thrombotic microangiopathy. Laskin B et al.
HSCT related TMA Elevated BP AKI + proteinuria Hemolysis( LDH, haptoglobin) Anemia Thromobocytopenia Causes BK, CMV, Adenovirus, HHV6,8, parvovirus b19 CNI, sirolimus Chemotherapy , radiation, Complement disorders, GVHD, cytokines, coagulation pathways Treatment Small vessels, big trouble in the kidney and beyond: hematopoietic stem cell transplantation -associated thrombotic microangiopathy. Laskin B et al.
HSCT related TMA Elevated BP AKI + proteinuria Hemolysis( LDH, haptoglobin) Anemia Thromobocytopenia Causes BK, CMV, Adenovirus, HHV6,8, parvovirus b19 CNI, sirolimus Chemotherapy , radiation, Complement disorders, GVHD, cytokines, coagulation pathways Treatment Alter GVHD treatment No data on TPE. Newer complement based therapies Small vessels, big trouble in the kidney and beyond: hematopoietic stem cell transplantation -associated thrombotic microangiopathy. Laskin B et al.
HSCT related TMA Elevated BP AKI + proteinuria Hemolysis( LDH, haptoglobin) Anemia Thromobocytopenia Causes BK, CMV, Adenovirus, HHV6,8, parvovirus b19 CNI, sirolimus Chemotherapy , radiation, Complement disorders, GVHD, cytokines, coagulation pathways Treatment Alter GVHD treatment No data on TPE. Newer complement based therapies Small vessels, big trouble in the kidney and beyond: hematopoietic stem cell transplantation -associated thrombotic microangiopathy. Laskin B et al.

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TA-TMA

  • 1. HSCT related TMA Elevated BP AKI + proteinuria Hemolysis( LDH, haptoglobin) Anemia Thromobocytopenia Causes Treatment Small vessels, big trouble in the kidney and beyond: hematopoietic stem cell transplantation -associated thrombotic microangiopathy. Laskin B et al.
  • 2. HSCT related TMA Elevated BP AKI + proteinuria Hemolysis( LDH, haptoglobin) Anemia Thromobocytopenia Causes BK, CMV, Adenovirus, HHV6,8, parvovirus b19 CNI, sirolimus Chemotherapy , radiation, Complement disorders, GVHD, cytokines, coagulation pathways Treatment Small vessels, big trouble in the kidney and beyond: hematopoietic stem cell transplantation -associated thrombotic microangiopathy. Laskin B et al.
  • 3. HSCT related TMA Elevated BP AKI + proteinuria Hemolysis( LDH, haptoglobin) Anemia Thromobocytopenia Causes BK, CMV, Adenovirus, HHV6,8, parvovirus b19 CNI, sirolimus Chemotherapy , radiation, Complement disorders, GVHD, cytokines, coagulation pathways Treatment Alter GVHD treatment No data on TPE. Newer complement based therapies Small vessels, big trouble in the kidney and beyond: hematopoietic stem cell transplantation -associated thrombotic microangiopathy. Laskin B et al.
  • 4. HSCT related TMA Elevated BP AKI + proteinuria Hemolysis( LDH, haptoglobin) Anemia Thromobocytopenia Causes BK, CMV, Adenovirus, HHV6,8, parvovirus b19 CNI, sirolimus Chemotherapy , radiation, Complement disorders, GVHD, cytokines, coagulation pathways Treatment Alter GVHD treatment No data on TPE. Newer complement based therapies Small vessels, big trouble in the kidney and beyond: hematopoietic stem cell transplantation -associated thrombotic microangiopathy. Laskin B et al.