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SWISS
 DOLORCLAST
APPLICATIONS
FOR PODIATRY
HISTORY
• EMS/Dolorclast was the first company to
  develop Lithotripsy
• Extracorporeal Shockwave Therapy
• (ESWT) was first used to treat kidney stones
• Since 1990 (ESWT) has been used for a
  variety of orthopaedic applications.
• More recently, it is used for treating wound
  ulcers, lymphodema, burns and cellulite
Indications for RSWT®

   Tennis elbow
   (Epicondilitis
   humeri radialis)                      Subacromial pain
                                         syndrome


  Greater trochanteric                    Golfer‘s elbow
  pain syndrome                           (epicondylitis
                                          humeri ulnaris)



Patellar tip syndrome                    Medial tibial stress
                                         syndrome


                                         Achilles
Plantar fasciopathy                      tendinopathy
MECHANISMS
• The procedure accelerates the body's own
  healing mechanisms by:-
• Generating impulses of high energy, high
  pressure sound waves that travel through
  skin to stimulate healing.
• It is effectively changing a chronic
  condition to an acute condition.
Radial extracorporeal shock wave therapy
                RSWT®
28.11.2011   Gloria Allery & Val Bryce   6
                                         6
RSWT®: basic physics (3) - cavitation
•   Which part of shock waves mediates their biological efffects on
    tissue?

•   "A significant tissue effect is cavitation consequent to the
    negative phase of the wave propagation."
•   (Ogden et al., 2001)
RSWT®: see shock waves on high speed movie:




                                              8
                                              8
RSWT®: basic physics - cavitation


                                     Cavitation bubbles
    Wave front



                                           Secondary
    Hydrophone                            shock waves
     (used to trigger
       a high-speed
             camera)


                        Applicator


                                                          9
                                                          9
9
SCIENTIFIC BACKGROUND

• ESWL can trigger a variety of effective
  actions
• Release more substance P
• Inhibits the COX11 enzyme
• Activates cellular defenses
• Hyper stimulates nerve fibres
RSWT RANDOM CONTROL TRIALS WITH POSITIVE
              OUTCOMES
       Chronic plantar fasciopathy
       •Gerdesmeyer et al., Am J Sports Med 2008; 36: 2100-2109
       •Chow and Cheing, Clin Rehab 2007;21: 131-141
       •Greve et al., Clinics 2009; 64: 97-103


       Midportion Achilles tendinopathy:
       •Rompe et al., Am J Sports Med 2007;35:374-381
       •Rompe et al., Am J Sports Med 2009;37:463-470


       Insertion Achilles tendinopathy:
       •Rompe et al., Am J Bone Joint Surg 2008;90:52-61


       Medial tibial stress syndrome:
       •Rompe et al., Am J Sports Med 2009 [Epub Sep 23]




11
PROBLEMS WITH DIABETIC
           FOOT
• Diabetes= Worldwide= over 200million
              Qld       = over 200,000
• Over 1 million diabetic amputations year
  worldwide
• Most common diabetic admissions
  Foot ulcers = more than 15%
  Amputations = more than 1-3%
STANDARD FOOT ULCER
          MANAGEMENT

•   Control infection
•   Improve blood supply
•   Optimise wound healing environment
•   Protect wound from trauma
TREATMENT
    ESWT in conjunction with standard
    therapies for off loading foot pressure
•   Padding
•   Insoles
•   Orthotics
•   Footwear- sandals boots, casts, splints
•   Walking aids, crutches, walking sticks,
    wheelchairs
Case Study
• This patient was treated at a Hairmyres Hospital,
  Scotland, and had a large diabetic foot ulcer.
  This had been surgically debrided and had also
  had larvae therapy. It was not responding to
  treatment and there was a real chance that the
  patient would need a lower leg amputation.
• The patient was treated with ESWT over a
  period of six months during which there was full
  healing. On average he was treated once every
  2.5 weeks.
Large diabetic foot ulcer-
    March 2010,prior to treatment
24th AUGUST 2010   5 TH October 2010
References
[1] R. Saggini, A. Figus, A. Troccola, V. Cocco, A.
Saggini, and N. Scuderi. Extracorporeal shock wave
therapy for management of chronic ulcers in the lower
extremities. Ultrasound Med Biol, 34(8):1261– 1271,
August 2008.
[2] W. Schaden, R. Thiele, C. Kolpl, M. Pusch, A.
Nissan, C. E. Attinger, M. E. Maniscalco-Theberge, G. E.
Peoples, E. A. Elster, and A. Stojadinovic. Shock wave
therapy for acute and chronic soft tissue wounds: a
feasibility study. J Surg Res, 143(1):1–12, 2007.
[3] A. M. Larking, S. Duport, M. Clinton, M. Hardy, and K.
Andrews. Randomized control of extracorporeal shock
wave therapy versus placebo for chronic decubitus
ulceration. Clin Rehabil, Feb 2010.
• [4] J. Dumfarth, D. Zimpfer, M. Vögele-Kadletz,
  J. Holfeld, F. Sihorsch, W. Schaden, M. Czerny,
  S. Aharinejad, E. Wolner, and M. Grimm.
  Prophylactic low-energy shock wave therapy
  improves wound healing after vein harvesting for
  coronary artery bypass graft surgery: A
  prospective, randomized trial. Ann Thorac Surg,
  86(6):1909–1913, December 2008.

• [5] C. Wang, Y. Kuo, R. Wu, R. Liu, C. Hsu, F.
  Wang, and K. Yang. Extracorporeal shockwave
  treatment for chronic diabetic foot ulcers. J Surg
  Res, 152, 96–103 (2009).
RSWT : summary
                         ®

→Physical mechanisms of action understood
     →Wave propagation
     →Cavitation
→Molecular and cellular mechanisms of action
 understood
     →Immediate pain relief by depletion of substance P
     →Blockade of neurogenic inflammation
     →Change of gene expression in adult stem cells
      towards healing

20
→Happy patients
→Efficacy and safety demonstrated in various
 RCTs
  →Evidence-Based Medicine Level 1
  →Fast (3 x 5 min treatment) with immediate benefit
  →Negligible side effects when applied properly (skin
   reddening)
  →No injections, no cortisone, no surgery!
  →No doping!
A treatment modality becomes successful when...

          ∀ →we know how it works
          ∀ →we know that it works
          ∀ →we know why it works


→your patients become enthusiastic about it!

Enthusiastic patients – successful practice!

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Swiss dolorclast applications for podiatrty

  • 2. HISTORY • EMS/Dolorclast was the first company to develop Lithotripsy • Extracorporeal Shockwave Therapy • (ESWT) was first used to treat kidney stones • Since 1990 (ESWT) has been used for a variety of orthopaedic applications. • More recently, it is used for treating wound ulcers, lymphodema, burns and cellulite
  • 3. Indications for RSWT® Tennis elbow (Epicondilitis humeri radialis) Subacromial pain syndrome Greater trochanteric Golfer‘s elbow pain syndrome (epicondylitis humeri ulnaris) Patellar tip syndrome Medial tibial stress syndrome Achilles Plantar fasciopathy tendinopathy
  • 4. MECHANISMS • The procedure accelerates the body's own healing mechanisms by:- • Generating impulses of high energy, high pressure sound waves that travel through skin to stimulate healing. • It is effectively changing a chronic condition to an acute condition.
  • 5. Radial extracorporeal shock wave therapy RSWT®
  • 6. 28.11.2011 Gloria Allery & Val Bryce 6 6
  • 7. RSWT®: basic physics (3) - cavitation • Which part of shock waves mediates their biological efffects on tissue? • "A significant tissue effect is cavitation consequent to the negative phase of the wave propagation." • (Ogden et al., 2001)
  • 8. RSWT®: see shock waves on high speed movie: 8 8
  • 9. RSWT®: basic physics - cavitation Cavitation bubbles Wave front Secondary Hydrophone shock waves (used to trigger a high-speed camera) Applicator 9 9 9
  • 10. SCIENTIFIC BACKGROUND • ESWL can trigger a variety of effective actions • Release more substance P • Inhibits the COX11 enzyme • Activates cellular defenses • Hyper stimulates nerve fibres
  • 11. RSWT RANDOM CONTROL TRIALS WITH POSITIVE OUTCOMES Chronic plantar fasciopathy •Gerdesmeyer et al., Am J Sports Med 2008; 36: 2100-2109 •Chow and Cheing, Clin Rehab 2007;21: 131-141 •Greve et al., Clinics 2009; 64: 97-103 Midportion Achilles tendinopathy: •Rompe et al., Am J Sports Med 2007;35:374-381 •Rompe et al., Am J Sports Med 2009;37:463-470 Insertion Achilles tendinopathy: •Rompe et al., Am J Bone Joint Surg 2008;90:52-61 Medial tibial stress syndrome: •Rompe et al., Am J Sports Med 2009 [Epub Sep 23] 11
  • 12. PROBLEMS WITH DIABETIC FOOT • Diabetes= Worldwide= over 200million Qld = over 200,000 • Over 1 million diabetic amputations year worldwide • Most common diabetic admissions Foot ulcers = more than 15% Amputations = more than 1-3%
  • 13. STANDARD FOOT ULCER MANAGEMENT • Control infection • Improve blood supply • Optimise wound healing environment • Protect wound from trauma
  • 14. TREATMENT ESWT in conjunction with standard therapies for off loading foot pressure • Padding • Insoles • Orthotics • Footwear- sandals boots, casts, splints • Walking aids, crutches, walking sticks, wheelchairs
  • 15. Case Study • This patient was treated at a Hairmyres Hospital, Scotland, and had a large diabetic foot ulcer. This had been surgically debrided and had also had larvae therapy. It was not responding to treatment and there was a real chance that the patient would need a lower leg amputation. • The patient was treated with ESWT over a period of six months during which there was full healing. On average he was treated once every 2.5 weeks.
  • 16. Large diabetic foot ulcer- March 2010,prior to treatment
  • 17. 24th AUGUST 2010 5 TH October 2010
  • 18. References [1] R. Saggini, A. Figus, A. Troccola, V. Cocco, A. Saggini, and N. Scuderi. Extracorporeal shock wave therapy for management of chronic ulcers in the lower extremities. Ultrasound Med Biol, 34(8):1261– 1271, August 2008. [2] W. Schaden, R. Thiele, C. Kolpl, M. Pusch, A. Nissan, C. E. Attinger, M. E. Maniscalco-Theberge, G. E. Peoples, E. A. Elster, and A. Stojadinovic. Shock wave therapy for acute and chronic soft tissue wounds: a feasibility study. J Surg Res, 143(1):1–12, 2007. [3] A. M. Larking, S. Duport, M. Clinton, M. Hardy, and K. Andrews. Randomized control of extracorporeal shock wave therapy versus placebo for chronic decubitus ulceration. Clin Rehabil, Feb 2010.
  • 19. • [4] J. Dumfarth, D. Zimpfer, M. Vögele-Kadletz, J. Holfeld, F. Sihorsch, W. Schaden, M. Czerny, S. Aharinejad, E. Wolner, and M. Grimm. Prophylactic low-energy shock wave therapy improves wound healing after vein harvesting for coronary artery bypass graft surgery: A prospective, randomized trial. Ann Thorac Surg, 86(6):1909–1913, December 2008. • [5] C. Wang, Y. Kuo, R. Wu, R. Liu, C. Hsu, F. Wang, and K. Yang. Extracorporeal shockwave treatment for chronic diabetic foot ulcers. J Surg Res, 152, 96–103 (2009).
  • 20. RSWT : summary ® →Physical mechanisms of action understood →Wave propagation →Cavitation →Molecular and cellular mechanisms of action understood →Immediate pain relief by depletion of substance P →Blockade of neurogenic inflammation →Change of gene expression in adult stem cells towards healing 20
  • 21. →Happy patients →Efficacy and safety demonstrated in various RCTs →Evidence-Based Medicine Level 1 →Fast (3 x 5 min treatment) with immediate benefit →Negligible side effects when applied properly (skin reddening) →No injections, no cortisone, no surgery! →No doping!
  • 22. A treatment modality becomes successful when... ∀ →we know how it works ∀ →we know that it works ∀ →we know why it works →your patients become enthusiastic about it! Enthusiastic patients – successful practice!

Editor's Notes

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