Suicide in middle age can arise from physical, psychological, or sociological issues according to the document. Physical issues like sudden illness, genetic diseases, or substance abuse may contribute. Psychological factors such as sudden loss, mental illness, or a midlife crisis also increase risk. Sociological challenges with identity, gender roles, or seeking social influence could play a role as well. While suicide is often associated with specific age groups, the document argues that suicide in middle age may be more influenced by situational factors than age alone.