Staphylococcus Aureus in burn intensive care unit
•
0 likes•37 views
This is a presentation about an article (not mine) that develops an interesting topic for heatlh personal. Staphylococcus Aureus is the most common bacteria involved in post operative infections and one of the most important to consider when talking about nosocomial infections.
Report
Share
Report
Share
Download to read offline
Recommended
New critical care issues 2015 17
This document discusses new insights into treatment strategies for critically ill patients, including optimal antibiotic dosing and the potential benefits of extended infusion of antibiotics. It also reviews evidence on the use of aerosolized colistin, inhalation antibiotics, statins, probiotics, and prophylactic antibiotics in preventing infections like ventilator-associated pneumonia in ICU patients. While some studies found decreased infection rates, ICU stay, or ventilation time with these approaches, larger trials are still needed to determine clear effects on mortality or define best practices. The document emphasizes individualizing care based on pharmacokinetic factors and calls for more research on optimization of antibiotic use in critical illness.
Antimicrobial resistance in bacteria
The document discusses antimicrobial resistance in bacteria. It begins by defining antimicrobial resistance as the ability of microorganisms to resist antimicrobial agents that they were previously susceptible to. The two main types are acquired resistance, which occurs when bacteria gain resistance genes, and intrinsic resistance, which refers to innate resistance in certain bacterial species. The overuse and misuse of antimicrobials is identified as the primary driver in the emergence and spread of resistant bacteria. The mechanisms by which bacteria develop resistance are explored, such as decreasing drug permeability, active drug efflux, and enzymatic inactivation or modification of drug targets. Methods for laboratory testing of bacterial resistance are also summarized.
Combating Drug resistance
Drug resistance occurs through several mechanisms: mutation, selective pressure, and gene transfer allow microbes to develop resistance. Strategies to combat resistance include international collaboration on surveillance and incentives for new drugs, national treatment guidelines and education programs, and community efforts like rational antibiotic use and hygiene. Genetic changes allow microbes to develop resistance through various mechanisms like mutation, selective pressure, and horizontal gene transfer between microbes.
Antimicrobial resistance
This document discusses antimicrobial resistance and provides information on various related topics. It begins with definitions of antimicrobials and antimicrobial resistance. It then explains why antimicrobial resistance is a concern due to increased mortality, treatment failure, and selection pressure. The document categorizes resistance into intrinsic and acquired resistance and describes various mechanisms of resistance including drug impermeable, drug destroying, and drug tolerant mechanisms. It also discusses cross-resistance and provides examples of antibiotic resistant bacteria. Finally, it introduces phage therapy as an alternative treatment approach to address antimicrobial resistance issues.
Multi drug resistant
Multi-drug resistant tuberculosis (MDR-TB) arises from inadequate or incomplete treatment that allows bacteria to develop resistance to multiple drugs. MDR-TB bacteria resist key first-line drugs like isoniazid and rifampin and require lengthy treatment with second-line drugs. The development of drug resistance threatens global TB control and highlights the need for improved diagnostics, treatment monitoring, and antibiotic stewardship to limit resistance.
Bacterial drug resistance
This document discusses the history and mechanisms of antimicrobial resistance. It begins with an overview and then discusses the history of antibiotic resistance, how it was first observed by Alexander Fleming. It explains intrinsic and acquired resistance in bacteria, how resistance can be transmitted between organisms, and various mechanisms of resistance including efflux pumps, enzymatic inactivation, and modification of drug targets. The document provides specific examples of resistance mechanisms for different classes of antibiotics in various bacterial species.
Combating Drug Resistance in The Intensive Care Unit (ICU)
Drug resistance of microbes has become a major challenge in treating ICU patients successfully. There are many factors that contribute to the development of drug resistance, including irrational antibiotic use, lack of antibiotic stewardship programs, and poor infection control practices. Implementing strict antibiotic policies, having responsive microbiology departments, and educating healthcare providers on following clinical guidelines are important first steps to prevent drug resistance. It is also essential to monitor antibiotic use, tailor therapies based on culture results, and withdraw antibiotics appropriately once infections have resolved. A multifaceted approach involving hospitals, healthcare workers, and communities is needed to curb the growing issue of antimicrobial resistance.
Antimicrobial resistance: Antibiotic resistance aproach.
Resistance to antibiotics is one of the main important facts that most nations are working on. Actually, in USA, it is considered as a health problem to solve. Why it happens? Here is a review to answer this.
Recommended
New critical care issues 2015 17
This document discusses new insights into treatment strategies for critically ill patients, including optimal antibiotic dosing and the potential benefits of extended infusion of antibiotics. It also reviews evidence on the use of aerosolized colistin, inhalation antibiotics, statins, probiotics, and prophylactic antibiotics in preventing infections like ventilator-associated pneumonia in ICU patients. While some studies found decreased infection rates, ICU stay, or ventilation time with these approaches, larger trials are still needed to determine clear effects on mortality or define best practices. The document emphasizes individualizing care based on pharmacokinetic factors and calls for more research on optimization of antibiotic use in critical illness.
Antimicrobial resistance in bacteria
The document discusses antimicrobial resistance in bacteria. It begins by defining antimicrobial resistance as the ability of microorganisms to resist antimicrobial agents that they were previously susceptible to. The two main types are acquired resistance, which occurs when bacteria gain resistance genes, and intrinsic resistance, which refers to innate resistance in certain bacterial species. The overuse and misuse of antimicrobials is identified as the primary driver in the emergence and spread of resistant bacteria. The mechanisms by which bacteria develop resistance are explored, such as decreasing drug permeability, active drug efflux, and enzymatic inactivation or modification of drug targets. Methods for laboratory testing of bacterial resistance are also summarized.
Combating Drug resistance
Drug resistance occurs through several mechanisms: mutation, selective pressure, and gene transfer allow microbes to develop resistance. Strategies to combat resistance include international collaboration on surveillance and incentives for new drugs, national treatment guidelines and education programs, and community efforts like rational antibiotic use and hygiene. Genetic changes allow microbes to develop resistance through various mechanisms like mutation, selective pressure, and horizontal gene transfer between microbes.
Antimicrobial resistance
This document discusses antimicrobial resistance and provides information on various related topics. It begins with definitions of antimicrobials and antimicrobial resistance. It then explains why antimicrobial resistance is a concern due to increased mortality, treatment failure, and selection pressure. The document categorizes resistance into intrinsic and acquired resistance and describes various mechanisms of resistance including drug impermeable, drug destroying, and drug tolerant mechanisms. It also discusses cross-resistance and provides examples of antibiotic resistant bacteria. Finally, it introduces phage therapy as an alternative treatment approach to address antimicrobial resistance issues.
Multi drug resistant
Multi-drug resistant tuberculosis (MDR-TB) arises from inadequate or incomplete treatment that allows bacteria to develop resistance to multiple drugs. MDR-TB bacteria resist key first-line drugs like isoniazid and rifampin and require lengthy treatment with second-line drugs. The development of drug resistance threatens global TB control and highlights the need for improved diagnostics, treatment monitoring, and antibiotic stewardship to limit resistance.
Bacterial drug resistance
This document discusses the history and mechanisms of antimicrobial resistance. It begins with an overview and then discusses the history of antibiotic resistance, how it was first observed by Alexander Fleming. It explains intrinsic and acquired resistance in bacteria, how resistance can be transmitted between organisms, and various mechanisms of resistance including efflux pumps, enzymatic inactivation, and modification of drug targets. The document provides specific examples of resistance mechanisms for different classes of antibiotics in various bacterial species.
Combating Drug Resistance in The Intensive Care Unit (ICU)
Drug resistance of microbes has become a major challenge in treating ICU patients successfully. There are many factors that contribute to the development of drug resistance, including irrational antibiotic use, lack of antibiotic stewardship programs, and poor infection control practices. Implementing strict antibiotic policies, having responsive microbiology departments, and educating healthcare providers on following clinical guidelines are important first steps to prevent drug resistance. It is also essential to monitor antibiotic use, tailor therapies based on culture results, and withdraw antibiotics appropriately once infections have resolved. A multifaceted approach involving hospitals, healthcare workers, and communities is needed to curb the growing issue of antimicrobial resistance.
Antimicrobial resistance: Antibiotic resistance aproach.
Resistance to antibiotics is one of the main important facts that most nations are working on. Actually, in USA, it is considered as a health problem to solve. Why it happens? Here is a review to answer this.
Management of antibiotic resistance upload
This document discusses antibiotic resistance and its management. It defines antibiotic resistance as when microorganisms become resistant to drugs that previously treated infections from them. It outlines various mechanisms of antibiotic resistance in microorganisms and lists priority resistant bacteria. It also discusses superbugs and different strategies to manage antibiotic resistance like prudent antibiotic use, infection control, developing new drugs, and reducing agricultural overuse of antibiotics.
Multi drug resistance
This document discusses mechanisms of multi-drug resistance in bacteria and cancer cells. It describes how organisms can develop resistance through mutation, gene transfer, decreased membrane permeability, and efflux pumps that remove drugs from cells. Specifically, it explains that bacteria resist antibiotics via enzymatic degradation, altered target sites, and increased efflux. Cancer cells similarly resist chemotherapy through efflux pumps like P-glycoprotein and MDR proteins that transport drugs out of cells. The key mechanisms of multi-drug resistance shared by bacteria and cancer are efflux pumps and enzymatic deactivation of drugs.
Presentation on Antibiotic and its Resistance
This topic contain slides on antibiotics and its resistance and also said what is role of pharmacist in management of antiboitics.
Multiple drug resistance
This document discusses multiple drug resistance (MDR) in bacteria. It begins by defining drug resistance and how bacteria can develop resistance through natural mechanisms or by acquiring resistance over time when exposed to antibiotics. The key points are:
- Bacteria can become resistant through mutations or gene transfer that make antibiotics unable to bind or enable the bacteria to destroy or pump out antibiotics.
- Multiple drug resistance (MDR) occurs when bacteria resist many different drug classes through various mechanisms like altered cell walls or target sites.
- Common MDR bacteria include MRSA, VRE, and ESBL-producing gram-negative bacteria.
- MDR-TB is also discussed, which is TB resistant to at least is
Antibiotic resistance I Mechanism I Types I Contributing factors.
Antibiotic resistance in bacteria is a global threat of 21st century. Here is a brief discussion of Antimicrobial resistance or Drug resistance disease. If you want to study via video lecture on this visit on my YouTube channel : Microbiology WISDOM:
Here you can find further more such interesting topics.
Infection Control and Antibiotic resistance
This document discusses antimicrobial resistance and strategies to address it. It notes that antibiotic overuse has led to many resistant infections worldwide. To combat this, the WHO advocates a coordinated, multi-sector response including prudent antibiotic use, infection control, surveillance, and new drug development. Key strategies to reduce resistant infections in healthcare facilities include antibiotic stewardship programs, hand hygiene, isolation precautions, and developing treatment guidelines based on local resistance patterns.
Current scenario of antimicobial resistance
This document provides an overview of the current state of antimicrobial resistance (AMR) globally and in India. It discusses the history of antibiotic discovery and the consequent rise of resistance. Worldwide, antibiotic resistance poses a major burden according to analysts. In India, resistance levels to commonly used antibiotics like piperacillin-tazobactam are between 50-70% according to ICMR data from 2017. While some new drugs have been approved in recent years, resistance is emerging to these as well. Polymyxins and tigecycline remain treatments of last resort but have significant safety issues. Overall, the document concludes that a definite solution to the growing problem of AMR remains elusive.
Antimicrobial regimen selection
This document discusses factors to consider when selecting an antimicrobial regimen. It covers obtaining microbiology samples before initiating therapy, host and drug factors, and the pros and cons of combination therapy. Key signs of infection discussed include fever, white blood cell count, local signs, and organ-specific symptoms. Gram stain results are provided for 3 example patients presenting with respiratory infection. Host factors like age, pregnancy status, organ function, genetic factors, concomitant diseases and medications must all be considered when selecting the appropriate antimicrobial regimen.
antibiotics resistance
This document discusses antibiotics and antibiotic resistance. It begins with an introduction defining antibiotics and explaining the issues of antibiotic resistance. It then covers the history of antibiotics, sources of antibiotics including natural, semi-synthetic and synthetic sources, and ways antibiotics can be classified including by mechanism of action. The document discusses mechanisms of antibiotic resistance in bacteria and ways resistance can emerge. It concludes by discussing the need to better understand disease-causing microorganisms and move to more personalized antibiotic treatment given rising resistance, as well as the importance of continued research into new antibiotics and proper use and disposal of existing antibiotics.
Antibiotic: Abuse and Misuse
Antibiotic originally was intended to cure and treat disease. However, because of lack of proper education and awareness campaign, antibiotics now are widely abuse and misuse. Such abuse and misuse of antibiotics today are the culprit why we have emergence of new diseases and Bacterial Resistance.
Newer antibiotics and uses
This document discusses newer antibiotics and their uses. It introduces several classes of newer antibiotics, including oxazolidinones (linezolid), glycolipopeptides (daptomycin), glycopeptides (telavancin), and pleuromutilins (retapamulin). These newer drugs are effective against multidrug-resistant gram-positive pathogens like MRSA and VRE. The document reviews the mechanisms of action, indications, clinical trial results, and side effects of these newer antibiotic classes.
Proportion of carbapenem resistance among enterobacteriaceae isolates at the ...
Corresponding Author: Mugala Faridah, faridahmugala@gmail.com Department of Microbiology Makerere University, College of Health Sciences
Makerere University's 1st African Biomedical Scientists' Conference 2nd March 2019 at Kampala Kolping Hotel
Antibiotic resistance dr sachin
Dr. Sachin Verma is a young, diligent and dynamic physician. He did his graduation from IGMC Shimla and MD in Internal Medicine from GSVM Medical College Kanpur. Then he did his Fellowship in Intensive Care Medicine (FICM) from Apollo Hospital Delhi. He has done fellowship in infectious diseases by Infectious Disease Society of America (IDSA). He has also done FCCS course and is certified Advance Cardiac Life support (ACLS) and Basic Life Support (BLS) provider by American Heart Association. He has also done a course in Cardiology by American College of Cardiology and a course in Diabetology by International Diabetes Centre. He specializes in the management of Infections, Multiorgan Dysfunctions and Critically ill patients and has many publications and presentations in various national conferences under his belt. He is currently working in NABH Approved Ivy super-specialty Hospital Mohali as Consultant Intensivists and Physician.
Antibiotic resistance
Relative or complete lack of effect of antimicrobial agent against a previously susceptible microbe/pathogen.
It is an evolutionary principal that organism adopt genetically to change in their environment.
since the doubling time of bacteria can be as short as 20 mnt, there may be many generations in even a few hours, providing ample opportunity for evolutionary adaptation.
The phenomenon of resistance imposes serious constraints on the options available for the treatment of many bacterial infections.
The resistance to chemotherapeutic agents can also develop in protozoa, in multicellular parasites and in population of malignant cells.
Today there are different strains of S. aureus resistant to almost every form of antibiotic in use.
recent advances to overcome antibiotic resistance
This document discusses recent advances to overcome antibiotic resistance. It begins with an introduction to antibiotic resistance and defines some superbugs. It then discusses the history of antibiotics from Ehrlich discovering chemotherapy to current generations. Common causes and modes of resistance are described. New classes of antibiotics are discussed like oxazolidinones, glycopeptides, ketolides, glycylcyclines, carbapenems, and cephalosporins. New targets for next generation drugs and possible solutions to antibiotic resistance are also presented.
Antimicrobial chemotherapy
This document provides an overview of antimicrobial agents and chemotherapy. It begins with an introduction to the historical background of chemotherapy and defines antimicrobial agents and chemotherapy. It then classifies antimicrobial agents into four main categories: antibacterial, antifungal, antiviral, and antiparasitic. The mechanisms of action and general characteristics of antimicrobial drugs are described. Key differences between antimicrobial agents and chemotherapy are outlined. In conclusion, the document stresses the importance of understanding antimicrobial classification, mechanisms of action, and properties for optimal patient care and prevention of resistance.
Antibiotic resistance-MADHURI RUDRARAJU
The document discusses antibiotic resistance and its causes. It notes that antibiotic resistance was first discovered in 1929 by Alexander Fleming and antibiotics were widely used starting in the 1940s. It then discusses how bacteria can become resistant to antibiotics through various mechanisms like denying antibiotic access, modifying the antibiotic target, or pumping antibiotics out of the cell. The document outlines factors that contribute to resistance developing, like improper antibiotic usage, lack of compliance with treatment durations, and overuse of broad-spectrum antibiotics. It provides examples of bacteria that have developed significant resistance issues, like E. coli becoming resistant to third-generation cephalosporins and MRSA developing vancomycin resistance. The document concludes that controlling antibiotic overuse and improving hygiene are important
Princeton presentation
Antibiotic resistance is a growing public health threat as many bacterial infections are becoming increasingly difficult to treat. Alexander Fleming warned about antibiotic misuse leading to resistance in 1945. Currently, antibiotic resistance contributes to 700,000 annual deaths and could cause 10 million deaths annually by 2050 at a cost of $100 trillion. Bacteria develop resistance through genetic mutations that enable them to survive antibiotic exposure, which then spread between bacteria. Genome sequencing can now be used to monitor the spread of antibiotic resistance genes and improve treatment by rapidly identifying resistance profiles of bacterial pathogens.
Antibiotic resistance
How Antibiotic resistance happens, Mechanism of Antibiotic resistance,Newly invented Antibiotic resistance bacteria
Staphylococcus pseudintermedius Methicillin-resistant
Presentation about Methicillin-resistant Staphylococcus pseudintermedius synthesizes deoxyadenosine to cause persistent infection.
Made By: Santiago Ocampo, Maria Monica Noguera.
ADEREMI ALICE ADEPEJU (M. Tuberculosis and antibiotics resistance)-1.pptx
Mycobacterium tuberculosis is the bacteria that causes tuberculosis. Resistance to antibiotics is occurring as the bacteria changes over time and no longer responds to antibiotic treatments. Diagnostic tests for tuberculosis include the tuberculosis skin test, acid-fast stain, culture, and polymerase chain reaction. The document discusses the aims and benefits of drug susceptibility testing for tuberculosis as well as methods for ensuring patients adhere to full treatment regimens to prevent the spread of drug-resistant strains.
Invasive candidiasis the hidden cause of sepsis
This presentation includes the definition, epidemiology, diagnosis and management of invasive candidiasis from the ICU perspective
More Related Content
What's hot
Management of antibiotic resistance upload
This document discusses antibiotic resistance and its management. It defines antibiotic resistance as when microorganisms become resistant to drugs that previously treated infections from them. It outlines various mechanisms of antibiotic resistance in microorganisms and lists priority resistant bacteria. It also discusses superbugs and different strategies to manage antibiotic resistance like prudent antibiotic use, infection control, developing new drugs, and reducing agricultural overuse of antibiotics.
Multi drug resistance
This document discusses mechanisms of multi-drug resistance in bacteria and cancer cells. It describes how organisms can develop resistance through mutation, gene transfer, decreased membrane permeability, and efflux pumps that remove drugs from cells. Specifically, it explains that bacteria resist antibiotics via enzymatic degradation, altered target sites, and increased efflux. Cancer cells similarly resist chemotherapy through efflux pumps like P-glycoprotein and MDR proteins that transport drugs out of cells. The key mechanisms of multi-drug resistance shared by bacteria and cancer are efflux pumps and enzymatic deactivation of drugs.
Presentation on Antibiotic and its Resistance
This topic contain slides on antibiotics and its resistance and also said what is role of pharmacist in management of antiboitics.
Multiple drug resistance
This document discusses multiple drug resistance (MDR) in bacteria. It begins by defining drug resistance and how bacteria can develop resistance through natural mechanisms or by acquiring resistance over time when exposed to antibiotics. The key points are:
- Bacteria can become resistant through mutations or gene transfer that make antibiotics unable to bind or enable the bacteria to destroy or pump out antibiotics.
- Multiple drug resistance (MDR) occurs when bacteria resist many different drug classes through various mechanisms like altered cell walls or target sites.
- Common MDR bacteria include MRSA, VRE, and ESBL-producing gram-negative bacteria.
- MDR-TB is also discussed, which is TB resistant to at least is
Antibiotic resistance I Mechanism I Types I Contributing factors.
Antibiotic resistance in bacteria is a global threat of 21st century. Here is a brief discussion of Antimicrobial resistance or Drug resistance disease. If you want to study via video lecture on this visit on my YouTube channel : Microbiology WISDOM:
Here you can find further more such interesting topics.
Infection Control and Antibiotic resistance
This document discusses antimicrobial resistance and strategies to address it. It notes that antibiotic overuse has led to many resistant infections worldwide. To combat this, the WHO advocates a coordinated, multi-sector response including prudent antibiotic use, infection control, surveillance, and new drug development. Key strategies to reduce resistant infections in healthcare facilities include antibiotic stewardship programs, hand hygiene, isolation precautions, and developing treatment guidelines based on local resistance patterns.
Current scenario of antimicobial resistance
This document provides an overview of the current state of antimicrobial resistance (AMR) globally and in India. It discusses the history of antibiotic discovery and the consequent rise of resistance. Worldwide, antibiotic resistance poses a major burden according to analysts. In India, resistance levels to commonly used antibiotics like piperacillin-tazobactam are between 50-70% according to ICMR data from 2017. While some new drugs have been approved in recent years, resistance is emerging to these as well. Polymyxins and tigecycline remain treatments of last resort but have significant safety issues. Overall, the document concludes that a definite solution to the growing problem of AMR remains elusive.
Antimicrobial regimen selection
This document discusses factors to consider when selecting an antimicrobial regimen. It covers obtaining microbiology samples before initiating therapy, host and drug factors, and the pros and cons of combination therapy. Key signs of infection discussed include fever, white blood cell count, local signs, and organ-specific symptoms. Gram stain results are provided for 3 example patients presenting with respiratory infection. Host factors like age, pregnancy status, organ function, genetic factors, concomitant diseases and medications must all be considered when selecting the appropriate antimicrobial regimen.
antibiotics resistance
This document discusses antibiotics and antibiotic resistance. It begins with an introduction defining antibiotics and explaining the issues of antibiotic resistance. It then covers the history of antibiotics, sources of antibiotics including natural, semi-synthetic and synthetic sources, and ways antibiotics can be classified including by mechanism of action. The document discusses mechanisms of antibiotic resistance in bacteria and ways resistance can emerge. It concludes by discussing the need to better understand disease-causing microorganisms and move to more personalized antibiotic treatment given rising resistance, as well as the importance of continued research into new antibiotics and proper use and disposal of existing antibiotics.
Antibiotic: Abuse and Misuse
Antibiotic originally was intended to cure and treat disease. However, because of lack of proper education and awareness campaign, antibiotics now are widely abuse and misuse. Such abuse and misuse of antibiotics today are the culprit why we have emergence of new diseases and Bacterial Resistance.
Newer antibiotics and uses
This document discusses newer antibiotics and their uses. It introduces several classes of newer antibiotics, including oxazolidinones (linezolid), glycolipopeptides (daptomycin), glycopeptides (telavancin), and pleuromutilins (retapamulin). These newer drugs are effective against multidrug-resistant gram-positive pathogens like MRSA and VRE. The document reviews the mechanisms of action, indications, clinical trial results, and side effects of these newer antibiotic classes.
Proportion of carbapenem resistance among enterobacteriaceae isolates at the ...
Corresponding Author: Mugala Faridah, faridahmugala@gmail.com Department of Microbiology Makerere University, College of Health Sciences
Makerere University's 1st African Biomedical Scientists' Conference 2nd March 2019 at Kampala Kolping Hotel
Antibiotic resistance dr sachin
Dr. Sachin Verma is a young, diligent and dynamic physician. He did his graduation from IGMC Shimla and MD in Internal Medicine from GSVM Medical College Kanpur. Then he did his Fellowship in Intensive Care Medicine (FICM) from Apollo Hospital Delhi. He has done fellowship in infectious diseases by Infectious Disease Society of America (IDSA). He has also done FCCS course and is certified Advance Cardiac Life support (ACLS) and Basic Life Support (BLS) provider by American Heart Association. He has also done a course in Cardiology by American College of Cardiology and a course in Diabetology by International Diabetes Centre. He specializes in the management of Infections, Multiorgan Dysfunctions and Critically ill patients and has many publications and presentations in various national conferences under his belt. He is currently working in NABH Approved Ivy super-specialty Hospital Mohali as Consultant Intensivists and Physician.
Antibiotic resistance
Relative or complete lack of effect of antimicrobial agent against a previously susceptible microbe/pathogen.
It is an evolutionary principal that organism adopt genetically to change in their environment.
since the doubling time of bacteria can be as short as 20 mnt, there may be many generations in even a few hours, providing ample opportunity for evolutionary adaptation.
The phenomenon of resistance imposes serious constraints on the options available for the treatment of many bacterial infections.
The resistance to chemotherapeutic agents can also develop in protozoa, in multicellular parasites and in population of malignant cells.
Today there are different strains of S. aureus resistant to almost every form of antibiotic in use.
recent advances to overcome antibiotic resistance
This document discusses recent advances to overcome antibiotic resistance. It begins with an introduction to antibiotic resistance and defines some superbugs. It then discusses the history of antibiotics from Ehrlich discovering chemotherapy to current generations. Common causes and modes of resistance are described. New classes of antibiotics are discussed like oxazolidinones, glycopeptides, ketolides, glycylcyclines, carbapenems, and cephalosporins. New targets for next generation drugs and possible solutions to antibiotic resistance are also presented.
Antimicrobial chemotherapy
This document provides an overview of antimicrobial agents and chemotherapy. It begins with an introduction to the historical background of chemotherapy and defines antimicrobial agents and chemotherapy. It then classifies antimicrobial agents into four main categories: antibacterial, antifungal, antiviral, and antiparasitic. The mechanisms of action and general characteristics of antimicrobial drugs are described. Key differences between antimicrobial agents and chemotherapy are outlined. In conclusion, the document stresses the importance of understanding antimicrobial classification, mechanisms of action, and properties for optimal patient care and prevention of resistance.
Antibiotic resistance-MADHURI RUDRARAJU
The document discusses antibiotic resistance and its causes. It notes that antibiotic resistance was first discovered in 1929 by Alexander Fleming and antibiotics were widely used starting in the 1940s. It then discusses how bacteria can become resistant to antibiotics through various mechanisms like denying antibiotic access, modifying the antibiotic target, or pumping antibiotics out of the cell. The document outlines factors that contribute to resistance developing, like improper antibiotic usage, lack of compliance with treatment durations, and overuse of broad-spectrum antibiotics. It provides examples of bacteria that have developed significant resistance issues, like E. coli becoming resistant to third-generation cephalosporins and MRSA developing vancomycin resistance. The document concludes that controlling antibiotic overuse and improving hygiene are important
Princeton presentation
Antibiotic resistance is a growing public health threat as many bacterial infections are becoming increasingly difficult to treat. Alexander Fleming warned about antibiotic misuse leading to resistance in 1945. Currently, antibiotic resistance contributes to 700,000 annual deaths and could cause 10 million deaths annually by 2050 at a cost of $100 trillion. Bacteria develop resistance through genetic mutations that enable them to survive antibiotic exposure, which then spread between bacteria. Genome sequencing can now be used to monitor the spread of antibiotic resistance genes and improve treatment by rapidly identifying resistance profiles of bacterial pathogens.
Antibiotic resistance
How Antibiotic resistance happens, Mechanism of Antibiotic resistance,Newly invented Antibiotic resistance bacteria
What's hot (19)
Antibiotic resistance I Mechanism I Types I Contributing factors.
Antibiotic resistance I Mechanism I Types I Contributing factors.
Proportion of carbapenem resistance among enterobacteriaceae isolates at the ...
Proportion of carbapenem resistance among enterobacteriaceae isolates at the ...
Similar to Staphylococcus Aureus in burn intensive care unit
Staphylococcus pseudintermedius Methicillin-resistant
Presentation about Methicillin-resistant Staphylococcus pseudintermedius synthesizes deoxyadenosine to cause persistent infection.
Made By: Santiago Ocampo, Maria Monica Noguera.
ADEREMI ALICE ADEPEJU (M. Tuberculosis and antibiotics resistance)-1.pptx
Mycobacterium tuberculosis is the bacteria that causes tuberculosis. Resistance to antibiotics is occurring as the bacteria changes over time and no longer responds to antibiotic treatments. Diagnostic tests for tuberculosis include the tuberculosis skin test, acid-fast stain, culture, and polymerase chain reaction. The document discusses the aims and benefits of drug susceptibility testing for tuberculosis as well as methods for ensuring patients adhere to full treatment regimens to prevent the spread of drug-resistant strains.
Invasive candidiasis the hidden cause of sepsis
This presentation includes the definition, epidemiology, diagnosis and management of invasive candidiasis from the ICU perspective
IX CHEMOTHERAPY OF INFECTIOUS DISEASES.ppt
This document discusses principles of antimicrobial chemotherapy and classification of antimicrobial drugs. It summarizes mechanisms of action, microbial resistance mechanisms, and therapeutic uses of various classes of antibacterial agents including beta-lactam antibiotics (penicillins, cephalosporins), aminoglycosides, tetracyclines, macrolides and other inhibitors of bacterial cell wall synthesis and protein synthesis. Adverse effects of these drug classes are also briefly outlined.
Immunotherapeutic strategies against pathogen
Immunotherapy uses substances made by the body or in a laboratory to boost the immune system against pathogens. Strategies include active vaccines and cytokines to stimulate immunity, as well as passive transfers of antibodies, toxins, or immune cells. Applications include cancer therapy, allergy treatment, and fighting viral and fungal infections. Pros are precise targeting and long-lasting responses, while cons can include toxicity and lack of effectiveness for some individuals. Immunotherapy shows promise as a safer alternative to other treatments.
Ceftriaxone
Ceftriaxone is a third-generation cephalosporin antibiotic used to treat a variety of bacterial infections. It works by inhibiting bacterial cell wall synthesis and has concentration-independent bactericidal activity. It is administered via intramuscular or intravenous injection, distributes well throughout the body including cerebrospinal fluid, and has a half-life of 7-8 hours. Common indications include lower respiratory, urinary tract, and abdominal infections caused by both gram-positive and gram-negative bacteria. Notable adverse effects include phlebitis, gastrointestinal upset, and skin reactions.
immunostimulants
This document summarizes immunostimulant drugs and immunotherapy. It describes the innate and adaptive immune response and lists immunostimulant microbial products like BCG that boost immune function. Immunostimulant drugs include cytokines, thalidomide, and levamisole. Immunotherapy methods covered are active and passive vaccination, adoptive cell transfer, and cell-based vaccination. The document provides details on specific immunostimulant drugs and their uses and side effects.
Periodontal vaccines
This document discusses periodontal vaccines and their potential role in preventing periodontal disease. It provides background on periodontal disease, outlines key periodontal pathogens like Porphyromonas gingivalis and Actinomyces actinomycetemcomitans, and summarizes different vaccine approaches - including active immunization using whole cells/subunits/peptides, passive immunization using monoclonal antibodies or plantibodies, and genetic immunization using plasmid or viral vectors. While animal studies show promise, translating vaccine efficacy to humans and clinical use remains challenging due to the complex multifactorial nature of periodontal disease. Future research opportunities include multispecies vaccines targeting multiple pathogens and genomic approaches.
Association of Hygiene Hypothesis with High prevalence of Allergy and Autoimm...
Association of Hygiene Hypothesis with High prevalence of Allergy and Autoimm...Agriculture Journal IJOEAR
Prevalence of Allergy and Autoimmune Diseases are high in developed countries, but not in developing countries. Helminth infection were associated with lower level of allergy but the mechanism is not yet clear. In hygiene countries like UK, Japan and Korea, Fecal Microbiota Transplantation (FMT) has gained interest as novel therapy and prevention and reach to medicine industrial manufactures. This study will support it by associate Hygiene Hypothesis (HyHy) and the high prevalence of Allergy and Autoimmune Disease. Systematic review and Bayesian network analysis in EBSCO host search engine were used. Result from dynaMed Evidence Based, Point-of-care Reference e Journals: Dentistry, Medical and Nursing has describe 9 literatures support the association of Hy-hy/parasite infection with Allergy and/ or Autoimmune Diseases: 2 publications of meta-analysis are chosen and supported by 5 cross sectional, longitudinal, cause-effect design, and 2 clinical and animal trial. Conclusions: Low-middle-high income countries has a life style of Hyhy pattern support FMT industrial medicine and travelling to developing countries with broad diversity bacteria and worm in therapeutic and prevention potential, supported by sub-saharan and tropical rainforest developing countries.Patient safety goal 4 : Tackling Antimicrobial Resistance
This document outlines Patient Safety Goal 4 to tackle antimicrobial resistance as part of WHO's 3rd Global Patient Safety Challenge. It describes 3 indicators to monitor the incidence of MRSA, ESBL-Klebsiella Pneumoniae, and ESBL-E.coli infections. Data on newly identified multidrug resistant organism cases will be collected and the infection rates calculated monthly. Strategies like implementing antibiotic guidelines, stewardship programs, and national campaigns aim to optimize antibiotic use and contain the spread of antimicrobial resistance.
An tibiotic policy in medical care seminar
This document outlines an antibiotic policy and discusses the importance of prudent antibiotic usage to reduce antibiotic resistance. It notes that nearly half of hospitalized patients receive antibiotics. While antibiotics have been life-saving, their overuse for trivial infections, commercial pressures, and poverty have encouraged resistance. Antibiotic resistance arises from genetic changes and spread of R plasmids between bacteria. Indiscriminate antibiotic use in animals and humans has led to the spread of resistant organisms. The policy aims to reduce resistance by engaging all prescribers, restricting certain antibiotics, and ensuring adherence through surveillance and education. The roles of microbiologists, pharmacists, and continuous staff training are emphasized.
Git j club h pylori DTT21
This document discusses antibiotic resistance in Helicobacter pylori (H. pylori), a major human pathogen. It notes that resistance to antibiotics used to treat H. pylori infections is increasing globally and poses a serious threat. The mechanisms of single, multi, and heteroresistance in H. pylori are discussed. Optimizing treatment regimens, developing new drugs, using probiotics and alternative antibiotics, and performing antibiotic susceptibility testing are recommended to prevent further resistance and improve treatment outcomes. Molecular diagnostic methods show promise for non-invasive antibiotic susceptibility testing of H. pylori.
Decision making in systemic antibiotic therapy.pptx
This document discusses the use of systemic antibiotics as an adjunct to scaling and root planing in the treatment of periodontal disease. It provides information on types of antibiotic therapy, current understanding of the microbial etiology of periodontal disease, and guidelines for periodontal therapy. Systematic reviews have found additional benefits of adjunctive antibiotics including improved clinical attachment level gains and reduced risk of further attachment loss. However, questions remain about which specific antibiotics or combinations are most appropriate for different forms of periodontal infections. The document also discusses the rationale for using systemic antibiotics as well as their limitations when biofilms are present. It provides criteria for an ideal antibiotic for periodontal therapy and discusses various antibiotic options and their administration.
Bacteriophage therapy
This document discusses bacteriophage therapy as an alternative approach to antibiotic resistance. It begins with an introduction to antibiotic resistance and discusses the mechanisms and factors contributing to resistance. It then introduces bacteriophage or phages, describing their classification, life cycles, and mechanisms of infecting bacteria. The document outlines methods for preparing and administering phage therapy. It discusses advantages of phage therapy over antibiotics and provides examples of phage therapy applications in food and agriculture. Finally, it addresses some challenges to phage therapy including host range, bacterial debris in preparations, and lysogeny.
Tuberculosis MBBS FIRST YEAR MICROBIOLOGY
This document discusses tuberculosis (TB), caused by Mycobacterium tuberculosis. It affects the respiratory system. Key points:
- TB is a major global health problem, infecting over 2 billion people worldwide. It is more common in developing countries.
- Transmission occurs via airborne droplets from untreated pulmonary TB cases. People at highest risk include healthcare workers, miners, and immunocompromised individuals.
- Diagnosis involves microscopy, culture, tuberculin skin testing, chest imaging, and PCR. Treatment consists of a multi-drug regimen over 6-9 months, guided by sensitivity testing to prevent drug resistance. Prevention strategies include contact screening, BCG vaccination of newborns, and public
Antibiotics
This document provides an overview of antibiotics, including their history, classification, mechanisms of action, and principles of administration. It discusses how antibiotics are classified based on their targets in bacteria and spectra of activity. Common antibiotics are also reviewed, along with how bacteria can develop resistance through modifications to antibiotic targets, altered uptake or efflux, and antibiotic inactivation through enzymes. Proper dosing, timing, route, and monitoring of patients are important to achieve the desired therapeutic effects of antibiotics.
Allergy and Hypersensitivity
Allergic reactions are exaggerated immune responses that can damage the host. There are four main types of hypersensitivity reactions mediated by different mechanisms. Immunotherapy uses controlled exposure to allergens to reduce allergic symptoms and involves altering the immune response from a TH2 to a TH1 profile over time. Sublingual immunotherapy is an effective alternative to subcutaneous immunotherapy for treating allergic diseases.
Human parasite vaccines
This document discusses human parasite vaccines. It begins by explaining what vaccines do in stimulating the host's protective immune response. Developing effective parasite vaccines faces challenges including not fully understanding the parasite's life cycle and which stages elicit a protective immune response. Effective vaccines must produce long-lasting protection without boosting and be low-cost, stable, and safe. Progress has been limited for parasite vaccines due to parasites' ability to evade the immune system, uncertainty regarding which antigens stimulate protection, and differences between animal models and human immune responses. Major human parasitic diseases discussed include malaria, African sleeping sickness, Chagas disease, leishmaniasis, intestinal protozoa, schistosomiasis, onchocerciasis
Immuno stimulant
This document discusses various immunostimulant drugs and therapies that boost the immune system. It describes the innate and adaptive immune response and how immunostimulants can enhance both arms of the immune system. Specific immunostimulants discussed include BCG vaccine, cytokines, levamisole, thalidomide, isoprinosine, immunocycin, and immunoglobulins. Vaccines, adjuvants, adoptive cell transfer, and dendritic cell-based vaccination are also covered as immunotherapies to strengthen immune defenses against infections and cancer.
Similar to Staphylococcus Aureus in burn intensive care unit (20)
Staphylococcus pseudintermedius Methicillin-resistant
Staphylococcus pseudintermedius Methicillin-resistant
ADEREMI ALICE ADEPEJU (M. Tuberculosis and antibiotics resistance)-1.pptx
ADEREMI ALICE ADEPEJU (M. Tuberculosis and antibiotics resistance)-1.pptx
Association of Hygiene Hypothesis with High prevalence of Allergy and Autoimm...
Association of Hygiene Hypothesis with High prevalence of Allergy and Autoimm...
Impact of tuberculosis pathogenesis and management
Impact of tuberculosis pathogenesis and management
Patient safety goal 4 : Tackling Antimicrobial Resistance
Patient safety goal 4 : Tackling Antimicrobial Resistance
Decision making in systemic antibiotic therapy.pptx
Decision making in systemic antibiotic therapy.pptx
Recently uploaded
Medical Quiz ( Online Quiz for API Meet 2024 ).pdf
This quiz was conducted as a promotional event for the 2024 Annual Meet of Kerala Chapter of API.
More than 20 participants took part everyday !
“Psychiatry and the Humanities”: An Innovative Course at the University of Mo...
“Psychiatry and the Humanities”: An Innovative Course at the University of Mo...Université de Montréal
“Psychiatry and the Humanities”: An Innovative Course at the University of Montreal Expanding the medical model to embrace the humanities. Link: https://www.psychiatrictimes.com/view/-psychiatry-and-the-humanities-an-innovative-course-at-the-university-of-montrealArtificial Intelligence Symposium (THAIS)
Artificial Intelligence Symposium (THAIS). Parc Taulí. Sabadell
STUDIES IN SUPPORT OF SPECIAL POPULATIONS: GERIATRICS E7
Unit 4: MRA 103T Regulatory affairs
This guideline is directed principally toward new Molecular Entities that are
likely to have significant use in the elderly, either because the disease intended
to be treated is characteristically a disease of aging ( e.g., Alzheimer's disease) or
because the population to be treated is known to include substantial numbers of
geriatric patients (e.g., hypertension).
Cervical Disc Arthroplasty ORSI 2024.pptx
Indication and installation of a mobile cervical disc prosthesis. Benefits of the PRODISC C VIVO mobile disc prosthesis (Centinel Spine)
SENSORY NEEDS B.SC. NURSING SEMESTER II.
Sensation is the neurological process by which we become aware of surrounding environment.
Post-Menstrual Smell- When to Suspect Vaginitis.pptx
Do you have abnormal smell after periods? It may be vaginitis. Do not worry, herbal medicine Fuyan Pill can help you get a cure.
NAVIGATING THE HORIZONS OF TIME LAPSE EMBRYO MONITORING.pdf
Time-lapse embryo monitoring is an advanced imaging technique used in IVF to continuously observe embryo development. It captures high-resolution images at regular intervals, allowing embryologists to select the most viable embryos for transfer based on detailed growth patterns. This technology enhances embryo selection, potentially increasing pregnancy success rates.
Breast cancer: Post menopausal endocrine therapy
Breast cancer in postmenopausal women with hormone receptor-positive (HR+) status is a common and complex condition that necessitates a multifaceted approach to management. HR+ breast cancer means that the cancer cells grow in response to hormones such as estrogen and progesterone. This subtype is prevalent among postmenopausal women and typically exhibits a more indolent course compared to other forms of breast cancer, which allows for a variety of treatment options.
Diagnosis and Staging
The diagnosis of HR+ breast cancer begins with clinical evaluation, imaging, and biopsy. Imaging modalities such as mammography, ultrasound, and MRI help in assessing the extent of the disease. Histopathological examination and immunohistochemical staining of the biopsy sample confirm the diagnosis and hormone receptor status by identifying the presence of estrogen receptors (ER) and progesterone receptors (PR) on the tumor cells.
Staging involves determining the size of the tumor (T), the involvement of regional lymph nodes (N), and the presence of distant metastasis (M). The American Joint Committee on Cancer (AJCC) staging system is commonly used. Accurate staging is critical as it guides treatment decisions.
Treatment Options
Endocrine Therapy
Endocrine therapy is the cornerstone of treatment for HR+ breast cancer in postmenopausal women. The primary goal is to reduce the levels of estrogen or block its effects on cancer cells. Commonly used agents include:
Selective Estrogen Receptor Modulators (SERMs): Tamoxifen is a SERM that binds to estrogen receptors, blocking estrogen from stimulating breast cancer cells. It is effective but may have side effects such as increased risk of endometrial cancer and thromboembolic events.
Aromatase Inhibitors (AIs): These drugs, including anastrozole, letrozole, and exemestane, lower estrogen levels by inhibiting the aromatase enzyme, which converts androgens to estrogen in peripheral tissues. AIs are generally preferred in postmenopausal women due to their efficacy and safety profile compared to tamoxifen.
Selective Estrogen Receptor Downregulators (SERDs): Fulvestrant is a SERD that degrades estrogen receptors and is used in cases where resistance to other endocrine therapies develops.
Combination Therapies
Combining endocrine therapy with other treatments enhances efficacy. Examples include:
Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer.
Endocrine Therapy with mTOR Inhibitors: Everolimus, an mTOR inhibitor, can be added to endocrine therapy for patients who have developed resistance to aromatase inhibitors.
Chemotherapy
Chemotherapy is generally reserved for patients with high-risk features, such as large tumor size, high-grade histology, or extensive lymph node involvement. Regimens often include anthracyclines and taxanes.
Pharmacology of 5-hydroxytryptamine and Antagonist
5-hydroxytryptamine or 5-HT or Serotonin is a neurotransmitter that serves a range of roles in the human body. It is sometimes referred to as the happy chemical since it promotes overall well-being and happiness.
It is mostly found in the brain, intestines, and blood platelets.
5-HT is utilised to transport messages between nerve cells, is known to be involved in smooth muscle contraction, and adds to overall well-being and pleasure, among other benefits. 5-HT regulates the body's sleep-wake cycles and internal clock by acting as a precursor to melatonin.
It is hypothesised to regulate hunger, emotions, motor, cognitive, and autonomic processes.
The Nervous and Chemical Regulation of Respiration
These lecture slides, by Dr Sidra Arshad, offer a simplified look into the mechanisms involved in the regulation of respiration:
Learning objectives:
1. Describe the organisation of respiratory center
2. Describe the nervous control of inspiration and respiratory rhythm
3. Describe the functions of the dorsal and respiratory groups of neurons
4. Describe the influences of the Pneumotaxic and Apneustic centers
5. Explain the role of Hering-Breur inflation reflex in regulation of inspiration
6. Explain the role of central chemoreceptors in regulation of respiration
7. Explain the role of peripheral chemoreceptors in regulation of respiration
8. Explain the regulation of respiration during exercise
9. Integrate the respiratory regulatory mechanisms
10. Describe the Cheyne-Stokes breathing
Study Resources:
1. Chapter 42, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 36, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 13, Human Physiology by Lauralee Sherwood, 9th edition
Pollen and Fungal allergy: aeroallergy.pdf
Pollen and Fungal allergy: aeroallergy.pdfChulalongkorn Allergy and Clinical Immunology Research Group
Pollen and Fungal allergy
Presented by Chaloemchai Chumsaengchotsakul, MD.
June 14, 2024Call Girls In Mumbai +91-7426014248 High Profile Call Girl Mumbai
Call Girls In Mumbai +91-7426014248 High Profile Call Girl Mumbai
What is Obesity? How to overcome Obesity?
Obesity is a chronic complex disease defined by excessive fat deposits that can impair health.
Pune Call Girls 7339748667 AVAILABLE HOT GIRLS AUNTY BOOK NOW
Pune Call Girls 7339748667 AVAILABLE HOT GIRLS AUNTY BOOK NOW
PGx Analysis in VarSeq: A User’s Perspective
Since our release of the PGx capabilities in VarSeq, we’ve had a few months to gather some insights from various use cases. Some users approach PGx workflows by means of array genotyping or what seems to be a growing trend of adding the star allele calling to the existing NGS pipeline for whole genome data. Luckily, both approaches are supported with the VarSeq software platform. The genotyping method being used will also dictate what the scope of the tertiary analysis will be. For example, are your PGx reports a standalone pipeline or would your lab’s goal be to handle a dual-purpose workflow and report on PGx + Diagnostic findings.
The purpose of this webcast is to:
Discuss and demonstrate the approaches with array and NGS genotyping methods for star allele calling to prep for downstream analysis.
Following genotyping, explore alternative tertiary workflow concepts in VarSeq to handle PGx reporting.
Moreover, we will include insights users will need to consider when validating their PGx workflow for all possible star alleles and options you have for automating your PGx analysis for large number of samples. Please join us for a session dedicated to the application of star allele genotyping and subsequent PGx workflows in our VarSeq software.
Recently uploaded (20)
Medical Quiz ( Online Quiz for API Meet 2024 ).pdf
Medical Quiz ( Online Quiz for API Meet 2024 ).pdf
“Psychiatry and the Humanities”: An Innovative Course at the University of Mo...
“Psychiatry and the Humanities”: An Innovative Course at the University of Mo...
STUDIES IN SUPPORT OF SPECIAL POPULATIONS: GERIATRICS E7
STUDIES IN SUPPORT OF SPECIAL POPULATIONS: GERIATRICS E7
Post-Menstrual Smell- When to Suspect Vaginitis.pptx
Post-Menstrual Smell- When to Suspect Vaginitis.pptx
NAVIGATING THE HORIZONS OF TIME LAPSE EMBRYO MONITORING.pdf
NAVIGATING THE HORIZONS OF TIME LAPSE EMBRYO MONITORING.pdf
Pharmacology of 5-hydroxytryptamine and Antagonist
Pharmacology of 5-hydroxytryptamine and Antagonist
The Nervous and Chemical Regulation of Respiration
The Nervous and Chemical Regulation of Respiration
Call Girls In Mumbai +91-7426014248 High Profile Call Girl Mumbai
Call Girls In Mumbai +91-7426014248 High Profile Call Girl Mumbai
Pune Call Girls 7339748667 AVAILABLE HOT GIRLS AUNTY BOOK NOW
Pune Call Girls 7339748667 AVAILABLE HOT GIRLS AUNTY BOOK NOW
Staphylococcus Aureus in burn intensive care unit
- 1. Presentadopor:SantiagoZapata L. ID: 000199219 IIISemestre Asignatura:Biología Molecular Facultadde Medicina EscueladeCienciasde la Salud UniversidadPontificiaBolivariana
- 2. Introduction: StaphylococcusAureus Type:gram-positive Shape:spherical Family:Micrococcaceae Size: 1 micrometer Colors:gray to yellow Characteristic: coagulase
- 3. Introduction: Methicillin/Resistance Methicillin is a Penicillin It’s a beta-lactam antibiotic It inhibits bacterial growth by interfering with the transpeptidation reaction of bacterial cell Wall synthesis Resistance could happen by four different mechanisms:
- 4. GeneralObjective The authors general objective was to report the successful control of a methicillin-resistant Staphylococcus Aureus outbreak in a burn intensive care unit by addition of universal decolonization with intranasal mupirocin to basic infection prevention measures
- 5. Methods: Basis MRSA-DNA MRSA Sma1 PGFE Comparing DNA PFGE:Pulsed-Field Gel Electrophoresis Technique:DNA fingerprint for bacterial isolate Sma1: restriction enzime
- 6. Methods:Argument Becausethey wanted to compare and characterize different MethicillinResistant Staphylococcus colonies Why didtheauthors used the previouslydescribed method?
- 7. Results (figure 1) 5 p/d BICU
- 10. Discusion AUTHOR(S) CONTRIBUTIONS COMPARISONWITHTHEARTICLE Patelet.al,Johnsonet.al &Grayet.al Usageof chlorhexidinegluconateor bleachsolutions, in additionto intranasalmupirocin, as decolonizationstrategies Septimus& Schweizer Nasal decolonizationalonemightlead to a reductionof MRSA infectionsy similarlyhigh-riskpopulations Leeet. al Testingof multipleanatomic sitesfor decolonization
- 11. Conclusions