Standard of Care - Ying Jiang

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Presentation delivered at "The State of Clinical Development Costs" conference in Philadelphia, PA January 11th and 12th, of 2011.

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SOC Analysis – Embolism and Deep Vein Thrombosis Study Study Duration 42 Days Number of Visits 13 Number of Patients 500 Number of Procedures 15 Number of SOC Procedures 7 Number of Expensive Procedures 0 Total Cost for Procedures Per Patient before SOC (w/ overhead) $4,808 USD Total Cost for Procedures Per Patient after SOC (w/ overhead) $3,515 USD Total SOC Savings Per Patient $1,293 USD Total SOC Savings for All Patients $646,365 USD Total % of SOC Savings 27%

SOC Analysis – Allergic and Asthmatic Bronchitis Study Study Duration 6 Months Number of Visits 10 Number of Patients 200 Number of Procedures 20 Number of SOC Procedures 9 Number of Expensive Procedures 0 Total Cost for Procedures Per Patient before SOC (w/ overhead) $3,499 USD Total Cost for Procedures Per Patient after SOC (w/ overhead) $2,669 USD Total SOC Savings Per Patient $830 USD Total SOC Savings for All Patients $166,050 USD Total % of SOC Savings 24%

SOC Analysis – Psoriatic Arthritis Study Study Duration 109 Weeks Number of Visits 16 Number of Patients 300 Number of Procedures 34 Number of SOC Procedures 12 Number of Expensive Procedures 0 Total Cost for Procedures Per Patient before SOC (w/ overhead) $13,625 USD Total Cost for Procedures Per Patient after SOC (w/ overhead) $10,430 USD Total SOC Savings Per Patient $3,195 USD Total SOC Savings for All Patients $958,500 USD Total % of SOC Savings 23%

SOC Analysis – Type 2 Diabetes Mellitus Study Study Duration 28 Weeks Number of Visits 29 Number of Patients 500 Number of Procedures 15 Number of SOC Procedures 8 Number of Expensive Procedures 0 Total Cost for Procedures Per Patient before SOC (w/ overhead) $4,210 USD Total Cost for Procedures Per Patient after SOC (w/ overhead) $3,257 USD Total SOC Savings Per Patient $953 USD Total SOC Savings for All Patients $476,625 USD Total % of SOC Savings 23%

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