This document provides an overview and analysis of the political cultures in Missouri and Illinois based on the scholarship of Daniel Elazar. It examines key differences between the two states, describing Missouri's culture as "traditionalistic" with an emphasis on interpersonal relationships, social hierarchy, and maintaining the status quo, while Illinois has a more "individualistic" culture centered around democracy, laissez-faire politics, and has historically struggled with corruption. The document also notes some challenges faced by the bi-state St. Louis region and opportunities for cooperation between Missouri and Illinois.