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胰島素的調整
李易軒
大綱
控制目標
控制方法
治療目標
理想體重
飯前 AC=70-130mg/dl
飯後 PC<180mg/dl
睡前AC=100-140mg/dl
HbA1C<7%
最理想的控制目標應在 6.5%以下
血壓<130/80
理想血壓應在 125/75mmHg
血脂控制
Total cholesterol<200
LDL(低密度脂蛋白):<100 mg/dl
TG(三酸甘油脂):<150 mg/dl
HDL(高密度脂蛋白):>40 mg/dl (男) ;
>50 mg/dl (女)
簡易調整法
血糖值 劑量
110-140 2u
140-180 4u
>180 6u
概念
一日insulin總量=體重x0.4~1.0(可以用BMI25kg/m2當作中間切點)
RI=Allx0.3~0.5
insulin 1 U 約降 20-60mg/dL
每份碳水化合物 (15Gm)約上升 20-60mg/dL
餐後血糖調整法
碳水化合物升糖值x份量—(PC—AC)
insulin當量
=insulin 單位用量 U
範例
身高168cm,體重60kg
BMI=21.25
RI 日總量=24~60 U
AC=90,PC=120
主食碳水化合物=4份(40mg/dL)
RI 當量=30 mg/dL
範例計算
)
30
4 U
(主食昇高血糖) (份) (飯後血糖) (飯前血糖)
(insulin當量)
40 x 4 120 90-(-
Regular insulin 調整法
血糖值 low <70 70-120 120-180 180-240 240-360 >360
早餐 -2 -1 0 +1 +2 +3
午餐 -2 -1 0 +1 +2 +3
晚餐 -2 -1 0 +1 +2 +3
睡前 -2 -1 0 +1 +2
混打調整(單一劑型)
方法 早上 晚上
平均法 1 1
重視早上 1/3 2/3
混打調整(分開劑型)
方法 早上 晚上
1 2/3 1/3
2
NPH RI NPH RI
2/3 1/3 1/2 1/2

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胰島素劑量調整