This document discusses immunoglobulin free light chains (FLC) and the κ/λ ratio. It contains the following key points:
1) FLC are produced in excess of heavy chains by plasma cells and any unbound light chains are known as free light chains.
2) An abnormal κ/λ ratio can indicate a clonal plasma cell disorder like multiple myeloma where either κ or λ chains are predominantly increased.
3) Measurement of FLC and the κ/λ ratio can aid in early diagnosis and monitoring of multiple myeloma and monoclonal gammopathy of unknown significance. It provides better sensitivity than traditional M-protein detection methods.
This document discusses immunoglobulin free light chains (FLC) and the κ/λ ratio. It contains the following key points:
1) FLC are produced in excess of heavy chains by plasma cells and any unbound light chains are known as free light chains.
2) An abnormal κ/λ ratio can indicate a clonal plasma cell disorder like multiple myeloma where either κ or λ chains are predominantly increased.
3) Measurement of FLC and the κ/λ ratio can aid in early diagnosis and monitoring of multiple myeloma and monoclonal gammopathy of unknown significance. It provides better sensitivity than traditional M-protein detection methods.
1) Discussão multiprofissional de caso clínico de paciente portador de esquizofrenia em atendimento ambulatorial. 2) Apresenta diagnóstico, histórico clínico e intervenções propostas por diferentes profissionais. 3) Inclui intervenções psicoterapêuticas, psicoeducativas, sociais, familiares, medicamentosas, legais e administrativas.
1) Discussão multiprofissional de caso clínico de paciente portador de esquizofrenia em atendimento ambulatorial. 2) Apresenta diagnóstico, histórico clínico e intervenções propostas por diferentes profissionais. 3) Inclui intervenções psicoterapêuticas, psicoeducativas, sociais, familiares, medicamentosas, legais e administrativas.