The Scrum Guide defines Scrum as a framework for developing and sustaining complex products, outlining its roles, events, artifacts, and rules. It emphasizes the importance of empirical process control, which includes transparency, inspection, and adaptation, and describes the roles of the scrum team—composed of the product owner, development team, and scrum master—and the specific events such as sprints and daily scrums. Overall, the guide provides a comprehensive overview of the Scrum methodology to enhance product management and development practices.