This document summarizes the history of drug laws in the United States from the 1700s to present day. It discusses early regulation of alcohol and opium, the 1906 Pure Food and Drug Act, the Harrison Narcotic Act of 1914, prohibition, the Marihuana Tax Act of 1937, and major drug laws passed in the 1960s-2000s that aimed to increase drug safety regulations, control narcotics, and enforce harsher penalties for drug offenses. It also explores debates around decriminalization, legalization, harm reduction strategies, and the impacts of the war on drugs.