This document summarizes the Siyakha Nentsha project which aims to improve the economic, health, and social capabilities of vulnerable youth in South Africa. The project provides evidence-based, multi-sectoral interventions on HIV/AIDS, reproductive health, and financial capabilities to adolescents at high risk of issues like early pregnancy, school dropout, and lack of opportunities. Quantitative and qualitative data is collected through surveys and focus groups to evaluate the impact on knowledge, behaviors, and well-being. Preliminary results show improvements in topics like partner reduction, condom use confidence, and STI knowledge for both males and females in the intervention groups.