2. It is a Syndrome characterized by decreased
tissue perfusion and impaired cellular
metabolism
Imbalance between the supply and demand for
O2 and nutrients
5. Cardiogenic shock is a condition in which heart
suddenly can't pump enough blood to meet body's
metabolic needs
6. Primary dysfunction of one ventricle or the other.
Dysfunction may be due to
Myocardial infarction
Cardiomyopathy
Blunt cardiac injury
Severe systemic or pulmonary hypertension
Cardiac tamponade
Myocardial depression from metabolic problems
9. Early manifestations
Tachycardia
Hypotension
Narrowed pulse pressure
↑ Myocardial O2 consumption
Late manifestations
Anxiety, restlessness, altered mental state due to decreased
blood flow to the brain and subsequent hypoxia.
Low blood pressure due to decrease in cardiac output.
10. A rapid, weak, thready pulse due to decreased
circulation combined with tachycardia.
Cool, clammy, and mottled skin (cutis marmorata)
due to vasoconstriction and subsequent
hypoperfusion of the skin.
Distended jugular veins due to increased jugular
venous pressure.
Oliguria (low urine output) due to inadequate blood
flow to the kidneys if the condition persists.
11. Rapid and deeper respirations (hyperventilation) due
to sympathetic nervous system stimulation and
acidosis.
Fatigue due to hyperventilation and hypoxia.
Absent pulse in fast and abnormal hear rhythms.
Pulmonary edema, involving fluid back-up in the
lungs due to insufficient pumping of the heart.
12. Electrocardiogram
An electrocardiogram helps establishing the exact
diagnosis and guides treatment, it may reveal:
Abnormal heart rhythms
myocardial infarction
Signs of cardiomyopathy
13. Echocardiography may show poor ventricular
function, rupture of the interventricular septum, an
obstructed outflow tract or cardiomyopathy.
Swan-Ganz catheter
The Swan-Ganz catheter or pulmonary artery
catheter may assist in the diagnosis by providing
information on the hemodynamics.
14. Biopsy
When cardiomyopathy is suspected as the cause of
cardiogenic shock, a biopsy of heart muscle may
be needed to make a definite diagnosis.
17. Limiting/reducing myocardial damage during
Myocardial Infarction:
Increased pumping action & decrease workload of the
heart
Inotropic agents
Vasoactive drugs
Intra-aortic balloon pump
Cautious administration of fluids
Transplantation
Consider thrombolytics, angioplasty in specific cases
18. OPTIMIZING PUMP FUNCTION:
Pulmonary artery monitoring is a necessity !!
Aggressive airway management: Mechanical Ventilation
Judicious fluid management
Vasoactive agents
Dobutamine
Dopamine
Morphine as needed (Decreases preload, anxiety)
Cautious use of diuretics in CHF
Vasodilators as needed for after load reduction
Short acting beta blocker, for refractory tachycardia
19.
20. Occurs from inadequate circulating blood volume
Major effects are due to decreased cardiac output
and low intra cardiac pressure
Severity of clinical features depends on degree of
blood volume lost
21. Hypovolemic shock, also known as
hemorrhagic shock, is a life-threatening condition
that results from lose of more than 20 percent
(one-fifth) of body's blood or fluid supply. This
severe fluid loss makes it impossible for the heart
to pump a sufficient amount of blood to the body.
22. Relative hypovolemia
Results when fluid volume moves out of the vascular
space into extravascular space (e.g., interstitial or
intracavitary space)
Termed third spacing
23. Internal or External fluid loss
Intracellular and extracellular compartments
Most common causes:
Hemmorhage
Dehydration
24. External loss of fluid
Fluid loss: Dehydration
Nausea & vomiting, diarrhea, massive diuresis
extensive burns
Blood loss:
trauma: blunt and penetrating
25. Internal fluid loss
Loss of Intravascular integrity
Increased capillary membrane permeability
Decreased Colloidal Osmotic Pressure
(third spacing)
32. Tachycardia and tachypnea
Weak, thready pulses
Hypotension
Skin cool & clammy
Mental status changes
Decreased urine output: dark & concentrated
33. Management goal: Restore circulating
volume, tissue perfusion, & correct cause:
Early Recognition- Do not relay on BP! (30% fluid
loss)
Control hemorrhage
Restore circulating volume
Optimize oxygen delivery
Vasoconstrictor if BP still low after volume loading
34. Inotropic therapy (Dopamine, Noradrenaline)
which increase the contractility of the heart muscle
Fresh frozen plasma or whole blood
35.
36. Neurogenic shock is a distributive type
of shock resulting in low blood pressure,
occasionally with a slowed heart rate, that is
attributed to the disruption of the autonomic
pathways within the spinal cord. It can occur after
damage to the central nervous system such as spinal
cord injury.
37. Neurogenic shock can result from severe central nervous
system damage
- brain injury,
- cervical or high thoracic spinal cord).
Neurogenic shock results from damage to the spinal cord
above the level of the 6th thoracic vertebra.
40. Hypotension
Bradycardia
Temperature dysregulation
(resulting in heat loss)
Dry skin
Poikilothermia (taking on the
temperature of the environment)
41. PATIENT
ASSESSMENT
Hypotension
Bradycardia
Hypothermia
Warm, dry skin
CO
Flaccid paralysis below
level of the spinal
MEDICAL
MANAGEMENT
Goals of Therapy are
to treat or remove the
cause & prevent
cardiovascular
instability, & promote
optimal tissue
perfusion
42. Dopamine (Intropin) is often used either alone or
in combination with other inotropic agents.
Vasopressin (antidiuretic hormone [ADH])
Certain vasopressors (ephedrine, norepinephrine).
Phenylephrine may be used as a first line
treatment, or secondarily in people who do not
respond adequately to dopamine.
Atropine is administered for slowed heart rate.
43. A type of distributive shock that results from
widespread systemic allergic reaction to an antigen
Anaphylactic shock is a severe, potentially life-
threatening allergic reaction. It can occur within
seconds or minutes of exposure to allergen.
44. certain medications such as penicillin
insect stings
foods such as tree nuts, shellfish, milk, and eggs
agents used in immunotherapy
latex
45.
46. Skin
⁻ Generalized hives.
⁻ Itching or flushing.
⁻ Swollen lips-tongue-uvula.
⁻ Per-orbital edema.
Respiratory
⁻ Nasal discharge and congestion.
⁻ Change in voice quality.
⁻ Sensation of throat closure or choking.
⁻ Tridor or wheeze.
⁻ Shortness of breath and cough.
48. Epinephrine
IM 0.3mg , 1:1000
IV 0.15mg , 1:10,000
Antihistamine
Corticosteroid
Bronchodilator
Oxygen
Fluids and vasopressors
49. Sepsis: Systemic inflammatory response to
documented or suspected infection
Severe sepsis = Sepsis + Organ dysfunction
50. Systemic Inflammatory Response (SIRS) to
INFECTION manifested by : two or > of
following:
Temp > 38 or < 36 centigrade
HR > 90
RR > 20 or PaCO2 < 32
WBC > 12,000/cu mm or < 4,000
> 10% Bands (immature wbc)
Sepsis syndrome: SIRS with confirmed
infectious process associate with organ failure
or hypotention
51. Age
Malnutrition
General debilitation
Use of invasive catheters
Traumatic wounds
Drug Therapy
52.
53. Two phases:
1.“Warm” shock - early phase
hyperdynamic response,
VASODILATION
2.“Cold” shock - late phase
hypodynamic response
DECOMPENSATED STATE
55. Vasoconistriction
Skin is pale & cold
Tachycardia
Decrease BP
Change LOC
Decrease UOP
Decrease CO
Metabolic &
respiratory acidosis
with hypoxemia
56. Prevention !!!
Find and kill the
source of the infection
Fluid Resuscitation
Vasoconstrictors
Inotropic drugs
Maximize O2
delivery Support
Nutritional Support
Comfort &
Emotional support