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Presented by: Dr. Aditi Jain
1st year PG
Popper (1963) Science is not a static acceptance of truth but rather the permanent search of
truth.
Department of Orthodontics and Dentofacial Orthopedics
Santosh Dental College, Deemed to be University
INTRODUCTION
The servo-system theory of growth was
given by Alexandre Petrovic, Charlier, and
Jeanne Stutzmann of Louis Pasteur school of
Medicine in the late 1960s.
It is based on factorial qualitative analysis
and describes the craniofacial growth
mechanisms and the modulus operandi of
functional and orthopedic appliances.
The servo-system theory relies on the
principle of cybernetics to describe the
growth of the craniofacial complex.
Alexander Petrovic 1923-2003
(France)
“I worship contradictory
CYBERNETICS
The term "CYBERNETICS (comes from
greek word kybernetes which means
steersman) was coined by mathematician
Norbert Wiener in 1948 to encompass the
entire field of control and communication
theory, whether in a machine or in an
animal.
Cybernetics is concerned with scientific
investigation of systematic processes of a
highly varied nature, including
phenomenon such as regulation,
information processing, storage,
adaptation, self organization and
strategic behavior.
CYBERNETICALLY ORGANIZED BIOLOGICAL
FEATURES
INPUT
Orthodontic and
orthopedic
appliances.
BLACK BOX OUTPUT
Correction of
malocclusion and
intermaxillary relation.
Genetically
determined and
cybernetically
organized biologic
feature of phenomena
characterizing,
including, controlling
spontaneous and
appliance-modulated
growth relative
primarily to the
following:-
• Maxillary
lengthening and
widening.
The physiological system under investigation is represented by BLACK BOX.
Cybernetically Organised System
operate
d
Physiological signals
Transmits information
Physic
al
Electromagn
etic
Chemica
l
Information Processing
Production, Perception, Transmission, And Storage Of
Information.
Not static
Sophisticated
A
D
V
A
N
T
A
G
E
S
Positive &
negative
feedback loops
Self regulation
INPUT OUTPU
T
Physiological Cybernetic
System
OPEN
LOOP
CONTROL
SYSTEM
CLOSED LOOP
Regulato
r
Servosyste
m
Feedbac
k
Comparato
r
Positiv
e
Negativ
e
Centra
l
Periphera
l
OPEN LOOP CONTROL SYSTEM
Environmental
Stimulus Recepto
r
Reflex
Transmission Perception Passive
Response
INPUT OUTPUT
CLOSED LOOP CONTROL SYSTEM
Transfer
Function
INPUT OUTPU
T
COMPARATOR
FEEDBACK
REGULATORY TYPE OF CLOSED LOOP
SERVOSYSTEM TYPE OF CLOSED LOOP
Control of
movement
s
Neural
Integration
Organic
Control
Receptor
Environmental
Stimulus
Feedback
Input is not
constant
SERVOSYSTE
M THEORY
1977
Shannon’s information theory
(1948) - designed to optimize the
transmission of information
through communication channels
The feed back
concept used in
engineering
control systems.
Petrovic and Charlier (1967-1969) – Jaw
growth rate and direction can be modified
through functional appliances.
Chronobiological aspects of cartilage and
bone growth
Jeanne Stutzmann
1976 The role of
LPM & postural
hyperpropulsor
temporomandibul
ar frenum
mediator role.
THE FACE AS A SERVOSYSTEM
Input- Any Changes In
Maxilla
(outward and forward
growth)
Output-
Adjustment
of the position
of mandible
COMPONENTS OF A SERVOSYSTEM
COMMAN
D
Reference
Input
COMPARATO
R
PERFORMANC
E
Coupling
System
Controlled
System
(Controlled Variable)
OUTPUT
CONTROLE
R
Performance Analyzing
Elements
ACTUATO
R
Constantly
Changing Inpu
Reference Input Elements
Central Comparator/Sensory
Deviation Signal
Peripheral
Comparator
GAIN
COMMAND
The command is a signal established
independent of the feedback system
in scrutiny and is not affected by the
output of the system.
It affects the behavior of the control
system without being affected by the
consequences of this behavior.
For instance, the secretion-rates of
growth hormone-somatomedin,
testosterone, and estrogen do not
seem to be modulated by variations of
craniofacial growth.
REFERENCE INPUT ELEMENT
They establish the relationship between Command
(Growth Hormone) and the Reference Input (Sagittal
Position of Maxilla).
Septal Cartilage, Septomaxillary Frenum, Labionarinary
Muscle, Premaxillary and Maxillary bone.
REFERENCE INPUT
• It is constantly changing
variable.
• Signal established as a
standard of comparison.
• Independent of the feedback
mechanisms.
• Sagittal Position of maxilla.
COMPARATO
R
Serves to establish the
relationship between the
reference input and controlled
variable.
“The operation of
confrontation” – Occlusal
contact between upper and
lower jaw.
Any deviation from optimal
occlusal contact detected by
the comparator leads to
PERFORMANC
E
The function
occurring by
peripheral
comparator that is
occlusion of
mandible and
maxilla is
mastication which is
the performance.
It is analyzed by
PERFORMANCE ANALYZING
ELEMENTS
They are periodontal ligament,
teeth, muscles,
temporomandibular joint.
 Proprioceptors within the
periodontal regions and
temporomandibular joint
perceive even a very small
occlusal discrepancy and
tonically activate the muscles
DEVIATION SIGNAL:
 Any input other than the
reference chosen by the
researcher is considered a
disturbance.
 The disturbance is
responsible for deviation of
the output signal and is thus
called deviation signal. It
may act on any element of
the regulating system.
 Abnormal Tooth position,
occlusal interferences,
arthritis, muscle
inflammation, periodontitis,
CONTROLL
ER
The BRAIN or the Central
Nervous System is the Central
Compactor also called as
Sensory engram or Controller.
ACTUATO
R
The actuator is the Motor Cortex
from where the signal is
transferred.
The actuating signal
corresponds to the output signal
of the controller (i.e., to the
input signal of the controlled
system).
 The activity of the Lateral
COUPLING
SYSTEM
The coupling system is
part of the control system
between the actuating
signal and the directly
controlled variable.
An example is the growth
of condylar cartilage via
metabolic blood
interchange in retrodiscal
pad.
CONTROLLED SYSTEM
The final output of the
system i.e. the OUTPUT
SIGNAL.
The Sagittal position of
Mandible.
Since it is not constant it is
also controlled variable
which keeps on changing
with the change in input.
GAIN
The gain of a system is the output
divided by the input.
 Gain > 1= Amplification.
Gain < 1 = Attenuation.
The pterygo-condylar coupling is an example of gain.
According to petrovic's investigation, the basal value of the
gain is determined genetically but may be amplified by growth
hormone-somatomedin and testosterone or attenuated by
estrogen. This is of great clinical significance.
Attractor
 Structurally stable steady state in dynamic system.
 Full interdigitation of the teeth.
 CLASS-I, CLASS-II, CLASS-III with cusp to fossa
relationship.
 The servosystem strives to achieve this stable form.
Repeller
 Unstable equilibrium state.
 Cusp to cusp type of occlusal relationship.
 The comparator detects this kind of disturbance
(Deviation signal) and tries to achieve the cusp to fossa
relationship through servosystem.
Feedback Signal
 The feedback signal is the function of the controlled
variable that is compared to the reference input. In a
regulator or servo-system, it is negative.
TYPES OF CARTILAGE
PRIMARY CARTILAGE:
Nasal septum, cartilage
between the body of
sphenoid, epiphysis,
SECONDARY CARTILAGE:
Condylar process, Coronoid
process, Mid- palatal
Suture, Fracture Callus
GROWTH AT CELLULAR LEVEL
CHONDROBLAST LOST (hypertrophy or surgically
removed)
INCREASED MULTIPLICATION OF
(Originates from Chondroblastic layer)
Functional appliances ( especially class 2 elastics)
Increased activity of RDP
Increased nutrients and growth factors supplied and inhibitors
removed
Increased mitosis and earlier hypertrophy of chondroblast
Reduced negative feedback signal reaching Prechondroblasts
Increased Growth at Condyle
Cytoplasmic Junctions between Skeletoblast
reduce
Transmission of inhibitory Factors reduce
Increased mitotic rate and rate of differentiation
into Prechondroblast
LOCAL FACTORS AFFECTING THE
CONDYLAR CARTILAGE
Consistent transmembrane ion flux variation.
Intra cellular Na ion concentration increased.
Intra cellular K ion concentration is decreased.
Discharge of H ions from blast cells is increased.
Increased pH.
Intracytoplasmic Ca++ concentration is low.
Thrust
Effect Ligame
nt
Muscle
traction
Spheno-occipital synchondrosis
Nasal septal cartilage
Lateral masses of ethmoid
Body and greater wing of
STH-
Stomatomedi
n
CONTROL OF THE MAXILLARY GROWTH
Forward
Growth
Of Septal
Cartilage
Outwar
d
Growth
FORWARD GROWTH OF SEPTAL
CARTILAGE
Thrust
Effect
Anterior Extremity of the Nasal Septal Cartilage
Spreads Laterally in Anterio-Inferior Direction
Penetrates into the Premaxillary Bone
Thrust
Effect
Premaxillomaxillary
Suture
Maxillopalatine
Suture
SEPTOPREMAXILLARY LIGAMENT
TRACTION
Growth of the
Nasal Septal
Cartilage
Traction effect on the
premaxillary bone through
the septomaxillary ligament.
TRACTION OF THE LABIONARINARI
MUSCLE
Traction of the premaxillary bone through
this muscle.
Biomechanics promotion of the forward
growth of the upper jaw.
Absence of labial muscle attachment on the
nasal septum – cleft lip- bone deformation.
OUTWARD
GROWTH
Outward growth of lateral Cartilaginous masses of the
ethmoid and the cartilage between the body and greater
wings of sphenoid.
Produces a lateralization of right and left
alveolar ridges
Stimulates the growth of mid-palatal suture
Outward growth of Maxilla
ROLE OF LPM AND RETRODISCAL PAD
Blood circulation:
Increase in open Loop
Factors.
Reduction in negative
feedback factors.
Biomechanical effect
For every unit of STH or testosterone that is released,
amount of growth is maximum. Mandible > Maxilla
At normal hormonal level N- good maxilla and
mandible relation is maintained.
At T2- hormonal level- (man> max)- LPM is reduced.
Beyond T2 hormonal level – LPM activity can no longer
be reduced – Prognathism
The opposite happens when hormonal level is below
T1 hormonal level – LPM activity can no longer be
increased- retrognathism.
Within levels T1- T2 , good maxilla and mandible
relation is maintained outside these levels:
GROWTH IN LENGTH OF MAXILLA
GROWTH IN WIDTH OF MAXILLA
Growth
Hormones
[STH-
Stomatomedin]
Sagittal
Position of
maxilla
OCCLUSION
MASTICATION
Lateral
pterygoid
muscle and
retrodiscal
pad
Growth at
condyle,
sagittal
position of
mandible
BRAIN Periodontium, teeth,
muscles and TMJ
Motor Cortex
Constantly
Changing Input
Septal Cartilage, Septomaxillary
Frenum, Labionarinary Muscle,
Premaxillary and Maxillary bone
Central Comparator/Sensory
Engram
Deviation Signal
Peripheral
Comparator
GAIN
MODE OF ACTION OF FUNCTIONAL
APPLIANCES
FUNCTIONAL APPLIANCES
INCREASED CONTRACTILE ACTIVITY OF LPM
INCREASE IN GROWTH STIMULATING FACTORS
ENHANCEMENT OF LOCAL MEDIATORS & REDUCTION IN
LOCAL REGULATORS
ADDITIONAL GROWTH OF THE CONDYLAR CARTILAGE
ADDITIONAL SUPER PERIOSTEAL OSSIFICATION
SUPPLEMENTARY LENGTHENING OF MANDIBLE
FUNCTIONAL APPLIANCES
1ST - GROUP
POSTULAR HYPERPROPULSOR
TWIN BLOCK
BIONATOR
ANDERSON HAUPL ACTIVATOR
CLASS II ELASTICS
FRANKEL’S APPLIANCE
2ND -GROUP
HERREN ACTIVATOR
LSU ACTIVATOR
HARVOLD WOODSIDE
ACTIVATOR
EXTRA ORAL TRACTION OF THE
MANDIBLE
Positions
Mandible
Forward
Increased
Activity of LPM &
RDP
Less fatigable
fibers in LPM
Oudet et el
(1988)
Carlson et el
(1990)
Positions
Mandible
Forward
1ST - GROUP
2ND - GROUP
Open in beyond
rest position
No Increased
Activity of
LPM.Yet increase
in Growth
Herren (1953)
Auf der Maur
(1978)
WHILE APPLIANCE IS
WORN
Forward position
 Reduction of length of LPM
New sensory engram
WHILE APPLIANCE IS
NOT WORN
New sensory engram
Functioning in anterior position
 Increased activity of RDP
Activity of 1st
Group
Activity of 2nd
Group
POSTURAL HYPERPROPULSOR
CLASS – II ELASTICS
Acts primarily through RDP rather LPM.
Alters the intrinsic regulation of the prechondroblastic multiplication.
Enhance the rate of hypertrophy of functional chondroblasts so that the
decreased amount of functional chondroblasts enhance prechondroblast
replication.
Similar to the effect of thyroxine.
TWIN BLOCK
Alters the occlusal inclined
planes.
70˚ inclined planes alter the
sensory engram and provide
a horizontal component of
force.
L.S.U. OR HERREN ACTIVATOR
Acts when appliance is not worn.
Action not mediated to through the LPM but through the
retrodiscal pad.
Shortening of the LPM when the appliance is worn compared to
other muscles.
A new sensory engram is produced.
The mandible closes in a more anterior position.
EFFECT OF CHIN CUP THERAPY
Retropulsion of the mandible results in reduction in number of
dividing cells.
Dividing cells if any are found anteriorly.
Resulting in anterior Growth rotation and decreased mandibular
Length.
CLINICAL IMPLICATIONS
• Principle of optimality of function:- less relapse
tendency if post orthodontic treatment muscular
activity produces a lower deviation signal.
• Removal of functional appliances when growth is
complete.
• If removed when growth not complete then we need
proper intercuspation.
• First group : full time , second group: part time .
• Proper functioning of LPM and RDP is important for growth –
parent counselling should be done properly.
• Sensory engram is poorly developed in younger children.
• Utilization of high hormonal activity at puberty.
CONSIDERATIONS OF SERVOSYSTEM
THEORY
Growth
Rotations
of the
Mandible
Alveolar
Bone
Turnover
Rate
BIFURCATION
Topologic Representation of increasing Hormone levels (testosterone or STH- stomatomedin) resulting
in supplementary growth of the mandible combined with lengthening of the maxilla as modulated by
the comparator of the servosystem (cuspal relief). Experimental results are expressed in terms of
PETROVIC’S GROWTH CATEGORIES
Growth Inequality of Bases
1 : Mandible equal to maxilla
2: Mandible smaller than maxilla
3 : Mandible greater than maxilla
Rotation of the Mandible
R : Neutral
P: Posterior rotation of mandible
A: Anterior Rotation of Mandible
Posteroanterior State
N: Normal
D: Distal
M: Mesial
Vertical State
N: Normal
OB: Open Bite
DB: Deep Bite
LEVEL -1
Cell and molecular
Biology Level
70%
3%
25%
Mandible
less than
Maxilla
Mandible
greater
than
Maxilla
Mandible equal to
Maxilla
Quantitative
determination
of difference
between
maxilla and
mandible.
LEVEL -2
Partly on Respiration
Phonation & Deglutition
Anterior Posterior
Neutral Relates to the
Growth
rotation and
growth
inclination of
both maxilla
and mandible
LEVEL -3
Unstable occlusion and
Functional Discontinuity
Distal Mesial
Normal
Based on the
occlusal
relationship
GROWTH ROTATIONS OF MANDIBLE
Morphogenetic
Rotations
Positional
Rotations
The Change in the
Shape of
Mandible
The Change in the
Position of
Mandible
in relation to the
Adjacent
Structures
Lavergene & Gasson
(1977)
ALVEOLAR BONE TURN OVER RATE
Tissue level Growth
Potential :
Level of
subperiosteal
ossification rate and
the level of alveolar
bone turnover rate
Tissue level Growth
Responsiveness:
The degree of
augmentation of the
alveolar bone turnover
resulting from
orthodontic treatment.
AUXOLOGIC GROUPS
Six auxologic categories of the
mandible.
Depends on:
1. tissue level growth potential
2. Tissue level Growth responsiveness to
orthodontic, orthopedic and functional
appliances.
Helps define the biologic inter-
individual variation of growing
mandible.
Clinicians must give importance to
tissue level growth responsiveness than
FAILURE OF SERVOSYSTEM TO
CONTROL GROWTH
Before development of
Occlusion
Sensory engram not developed
Servosystem does not operate
Genetic influence of mandibular
Growth
Anodontia
After Development of
Occlusion :-
Sensory Engram forms
Peripheral Comparator Control
Minimize possible deviation to
achieve stable occlusion.
Peripheral Comparator Faulty- Caries, Mutilated
Dentition
Discrepancy between rotation pattern (Anterior or
Posterior) and location of Comparator.
DRAWBACKS
The author places a lot of importance on the role of hormones in
controlling growth.
The peripheral comparator, the occlusion, itself is unstable.

According to this theory, an end on relation is a Repeller.
This theory places a lot of importance on condyle as growth center. If
condylar cartilage is lost, growth should seize. But some studies done
on Scandinavia show that this does not happen.
EVIDENCES AGAINST THE THEORY
Goret – Nicaise, Awn (1983) - Resection of LPM – Fails
to diminish condylar Growth.
Whetten and Jhonston (1985) – bilateral condylectomy
and unilateral LPM in rats – same growth on both sides.
Das, Myer & Sicher ( 1980) – Occlusion remained
unaffected in condylectomy studies.
CONCLUSION
While we may no longer seek a single synthesizing theory
for all of craniofacial growth, we now have, because of
petrovic’s work, a convenient model & a language by which
we can describe and relate growth activities to one another,
thus obviating any need for another paradigm.
The cybernetic theory of facial growth and the crucial -
topologic concept of structural and functional stability and
instability are highly useful in a systematic and increasingly
computerized approach to clinical situations.
REFERENCES
• GRABER, PETROVIC, RAKOSI. DENTOFACIAL ORTHOPAEDICS AND FUNCTIONAL
APPLIANCES, 2ND EDITION, 1917.
• ZHOU, Z.; LUO, S. (1998-05-01). "[DIFFERENTIAL EXPRESSION OF IGF-I AND ITS MRNA IN
MANDIBULAR CONDYLAR CARTILAGE OF RAT--DIRECT EVIDENCE FOR SERVOSYSTEM
THEORY OF FACIAL GROWTH]". HUA XI KOU QIANG YI XUE ZA ZHI = HUAXI KOUQIANG
YIXUE ZAZHI = WEST CHINA JOURNAL OF STOMATOLOGY. 16 (2): 164–165. ISSN 1000-
1182. PMID 12214426.
• HTTPS://WWW.SCRIBD.COM/DOCUMENT/383886681/PETROVIC.
• ROLE OF THE LATERAL PTERYGOID MUSCLE AND MENISCOTEMPOROMANDIBULAR
FRENUM IN SPONTANEOUS GROWTH OF THE MANDIBLE AND IN GROWTH STIMULATED BY
THE POSTURAL HYPERPROPULSOR J.J. STUTZMANN , A.G. PETROVIC
DOI:HTTPS://DOI.ORG/10.1016/0889-5406(90)70110-X.
• HTTPS://PHAIDRABG.BG.AC.RS/OPEN/O:21881
THANK YOU

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Servosystem Theory / Cybernetic Theory by Petrovic

  • 1. Presented by: Dr. Aditi Jain 1st year PG Popper (1963) Science is not a static acceptance of truth but rather the permanent search of truth. Department of Orthodontics and Dentofacial Orthopedics Santosh Dental College, Deemed to be University
  • 2. INTRODUCTION The servo-system theory of growth was given by Alexandre Petrovic, Charlier, and Jeanne Stutzmann of Louis Pasteur school of Medicine in the late 1960s. It is based on factorial qualitative analysis and describes the craniofacial growth mechanisms and the modulus operandi of functional and orthopedic appliances. The servo-system theory relies on the principle of cybernetics to describe the growth of the craniofacial complex. Alexander Petrovic 1923-2003 (France) “I worship contradictory
  • 3. CYBERNETICS The term "CYBERNETICS (comes from greek word kybernetes which means steersman) was coined by mathematician Norbert Wiener in 1948 to encompass the entire field of control and communication theory, whether in a machine or in an animal. Cybernetics is concerned with scientific investigation of systematic processes of a highly varied nature, including phenomenon such as regulation, information processing, storage, adaptation, self organization and strategic behavior.
  • 4. CYBERNETICALLY ORGANIZED BIOLOGICAL FEATURES INPUT Orthodontic and orthopedic appliances. BLACK BOX OUTPUT Correction of malocclusion and intermaxillary relation. Genetically determined and cybernetically organized biologic feature of phenomena characterizing, including, controlling spontaneous and appliance-modulated growth relative primarily to the following:- • Maxillary lengthening and widening. The physiological system under investigation is represented by BLACK BOX.
  • 5. Cybernetically Organised System operate d Physiological signals Transmits information Physic al Electromagn etic Chemica l Information Processing Production, Perception, Transmission, And Storage Of Information. Not static Sophisticated A D V A N T A G E S Positive & negative feedback loops Self regulation INPUT OUTPU T
  • 7. OPEN LOOP CONTROL SYSTEM Environmental Stimulus Recepto r Reflex Transmission Perception Passive Response INPUT OUTPUT
  • 8. CLOSED LOOP CONTROL SYSTEM Transfer Function INPUT OUTPU T COMPARATOR FEEDBACK
  • 9. REGULATORY TYPE OF CLOSED LOOP
  • 10. SERVOSYSTEM TYPE OF CLOSED LOOP Control of movement s Neural Integration Organic Control Receptor Environmental Stimulus Feedback Input is not constant
  • 11. SERVOSYSTE M THEORY 1977 Shannon’s information theory (1948) - designed to optimize the transmission of information through communication channels The feed back concept used in engineering control systems. Petrovic and Charlier (1967-1969) – Jaw growth rate and direction can be modified through functional appliances. Chronobiological aspects of cartilage and bone growth Jeanne Stutzmann 1976 The role of LPM & postural hyperpropulsor temporomandibul ar frenum mediator role.
  • 12. THE FACE AS A SERVOSYSTEM Input- Any Changes In Maxilla (outward and forward growth) Output- Adjustment of the position of mandible
  • 13. COMPONENTS OF A SERVOSYSTEM COMMAN D Reference Input COMPARATO R PERFORMANC E Coupling System Controlled System (Controlled Variable) OUTPUT CONTROLE R Performance Analyzing Elements ACTUATO R Constantly Changing Inpu Reference Input Elements Central Comparator/Sensory Deviation Signal Peripheral Comparator GAIN
  • 14. COMMAND The command is a signal established independent of the feedback system in scrutiny and is not affected by the output of the system. It affects the behavior of the control system without being affected by the consequences of this behavior. For instance, the secretion-rates of growth hormone-somatomedin, testosterone, and estrogen do not seem to be modulated by variations of craniofacial growth.
  • 15. REFERENCE INPUT ELEMENT They establish the relationship between Command (Growth Hormone) and the Reference Input (Sagittal Position of Maxilla). Septal Cartilage, Septomaxillary Frenum, Labionarinary Muscle, Premaxillary and Maxillary bone.
  • 16. REFERENCE INPUT • It is constantly changing variable. • Signal established as a standard of comparison. • Independent of the feedback mechanisms. • Sagittal Position of maxilla.
  • 17. COMPARATO R Serves to establish the relationship between the reference input and controlled variable. “The operation of confrontation” – Occlusal contact between upper and lower jaw. Any deviation from optimal occlusal contact detected by the comparator leads to
  • 18. PERFORMANC E The function occurring by peripheral comparator that is occlusion of mandible and maxilla is mastication which is the performance. It is analyzed by
  • 19. PERFORMANCE ANALYZING ELEMENTS They are periodontal ligament, teeth, muscles, temporomandibular joint.  Proprioceptors within the periodontal regions and temporomandibular joint perceive even a very small occlusal discrepancy and tonically activate the muscles
  • 20. DEVIATION SIGNAL:  Any input other than the reference chosen by the researcher is considered a disturbance.  The disturbance is responsible for deviation of the output signal and is thus called deviation signal. It may act on any element of the regulating system.  Abnormal Tooth position, occlusal interferences, arthritis, muscle inflammation, periodontitis,
  • 21. CONTROLL ER The BRAIN or the Central Nervous System is the Central Compactor also called as Sensory engram or Controller.
  • 22. ACTUATO R The actuator is the Motor Cortex from where the signal is transferred. The actuating signal corresponds to the output signal of the controller (i.e., to the input signal of the controlled system).  The activity of the Lateral
  • 23. COUPLING SYSTEM The coupling system is part of the control system between the actuating signal and the directly controlled variable. An example is the growth of condylar cartilage via metabolic blood interchange in retrodiscal pad.
  • 24. CONTROLLED SYSTEM The final output of the system i.e. the OUTPUT SIGNAL. The Sagittal position of Mandible. Since it is not constant it is also controlled variable which keeps on changing with the change in input.
  • 25. GAIN The gain of a system is the output divided by the input.  Gain > 1= Amplification. Gain < 1 = Attenuation. The pterygo-condylar coupling is an example of gain. According to petrovic's investigation, the basal value of the gain is determined genetically but may be amplified by growth hormone-somatomedin and testosterone or attenuated by estrogen. This is of great clinical significance.
  • 26. Attractor  Structurally stable steady state in dynamic system.  Full interdigitation of the teeth.  CLASS-I, CLASS-II, CLASS-III with cusp to fossa relationship.  The servosystem strives to achieve this stable form. Repeller  Unstable equilibrium state.  Cusp to cusp type of occlusal relationship.  The comparator detects this kind of disturbance (Deviation signal) and tries to achieve the cusp to fossa relationship through servosystem. Feedback Signal  The feedback signal is the function of the controlled variable that is compared to the reference input. In a regulator or servo-system, it is negative.
  • 27.
  • 28. TYPES OF CARTILAGE PRIMARY CARTILAGE: Nasal septum, cartilage between the body of sphenoid, epiphysis, SECONDARY CARTILAGE: Condylar process, Coronoid process, Mid- palatal Suture, Fracture Callus
  • 29.
  • 30. GROWTH AT CELLULAR LEVEL CHONDROBLAST LOST (hypertrophy or surgically removed) INCREASED MULTIPLICATION OF (Originates from Chondroblastic layer)
  • 31. Functional appliances ( especially class 2 elastics) Increased activity of RDP Increased nutrients and growth factors supplied and inhibitors removed Increased mitosis and earlier hypertrophy of chondroblast Reduced negative feedback signal reaching Prechondroblasts Increased Growth at Condyle
  • 32. Cytoplasmic Junctions between Skeletoblast reduce Transmission of inhibitory Factors reduce Increased mitotic rate and rate of differentiation into Prechondroblast
  • 33. LOCAL FACTORS AFFECTING THE CONDYLAR CARTILAGE Consistent transmembrane ion flux variation. Intra cellular Na ion concentration increased. Intra cellular K ion concentration is decreased. Discharge of H ions from blast cells is increased. Increased pH. Intracytoplasmic Ca++ concentration is low.
  • 34. Thrust Effect Ligame nt Muscle traction Spheno-occipital synchondrosis Nasal septal cartilage Lateral masses of ethmoid Body and greater wing of STH- Stomatomedi n CONTROL OF THE MAXILLARY GROWTH Forward Growth Of Septal Cartilage Outwar d Growth
  • 35. FORWARD GROWTH OF SEPTAL CARTILAGE Thrust Effect Anterior Extremity of the Nasal Septal Cartilage Spreads Laterally in Anterio-Inferior Direction Penetrates into the Premaxillary Bone Thrust Effect Premaxillomaxillary Suture Maxillopalatine Suture
  • 36. SEPTOPREMAXILLARY LIGAMENT TRACTION Growth of the Nasal Septal Cartilage Traction effect on the premaxillary bone through the septomaxillary ligament. TRACTION OF THE LABIONARINARI MUSCLE Traction of the premaxillary bone through this muscle. Biomechanics promotion of the forward growth of the upper jaw. Absence of labial muscle attachment on the nasal septum – cleft lip- bone deformation.
  • 37. OUTWARD GROWTH Outward growth of lateral Cartilaginous masses of the ethmoid and the cartilage between the body and greater wings of sphenoid. Produces a lateralization of right and left alveolar ridges Stimulates the growth of mid-palatal suture Outward growth of Maxilla
  • 38. ROLE OF LPM AND RETRODISCAL PAD Blood circulation: Increase in open Loop Factors. Reduction in negative feedback factors. Biomechanical effect
  • 39.
  • 40.
  • 41. For every unit of STH or testosterone that is released, amount of growth is maximum. Mandible > Maxilla At normal hormonal level N- good maxilla and mandible relation is maintained. At T2- hormonal level- (man> max)- LPM is reduced. Beyond T2 hormonal level – LPM activity can no longer be reduced – Prognathism The opposite happens when hormonal level is below T1 hormonal level – LPM activity can no longer be increased- retrognathism. Within levels T1- T2 , good maxilla and mandible relation is maintained outside these levels:
  • 42.
  • 43. GROWTH IN LENGTH OF MAXILLA
  • 44. GROWTH IN WIDTH OF MAXILLA
  • 45. Growth Hormones [STH- Stomatomedin] Sagittal Position of maxilla OCCLUSION MASTICATION Lateral pterygoid muscle and retrodiscal pad Growth at condyle, sagittal position of mandible BRAIN Periodontium, teeth, muscles and TMJ Motor Cortex Constantly Changing Input Septal Cartilage, Septomaxillary Frenum, Labionarinary Muscle, Premaxillary and Maxillary bone Central Comparator/Sensory Engram Deviation Signal Peripheral Comparator GAIN
  • 46.
  • 47. MODE OF ACTION OF FUNCTIONAL APPLIANCES FUNCTIONAL APPLIANCES INCREASED CONTRACTILE ACTIVITY OF LPM INCREASE IN GROWTH STIMULATING FACTORS ENHANCEMENT OF LOCAL MEDIATORS & REDUCTION IN LOCAL REGULATORS ADDITIONAL GROWTH OF THE CONDYLAR CARTILAGE ADDITIONAL SUPER PERIOSTEAL OSSIFICATION SUPPLEMENTARY LENGTHENING OF MANDIBLE
  • 48. FUNCTIONAL APPLIANCES 1ST - GROUP POSTULAR HYPERPROPULSOR TWIN BLOCK BIONATOR ANDERSON HAUPL ACTIVATOR CLASS II ELASTICS FRANKEL’S APPLIANCE 2ND -GROUP HERREN ACTIVATOR LSU ACTIVATOR HARVOLD WOODSIDE ACTIVATOR EXTRA ORAL TRACTION OF THE MANDIBLE
  • 49. Positions Mandible Forward Increased Activity of LPM & RDP Less fatigable fibers in LPM Oudet et el (1988) Carlson et el (1990) Positions Mandible Forward 1ST - GROUP 2ND - GROUP Open in beyond rest position No Increased Activity of LPM.Yet increase in Growth Herren (1953) Auf der Maur (1978)
  • 50. WHILE APPLIANCE IS WORN Forward position  Reduction of length of LPM New sensory engram WHILE APPLIANCE IS NOT WORN New sensory engram Functioning in anterior position  Increased activity of RDP Activity of 1st Group Activity of 2nd Group
  • 52. CLASS – II ELASTICS Acts primarily through RDP rather LPM. Alters the intrinsic regulation of the prechondroblastic multiplication. Enhance the rate of hypertrophy of functional chondroblasts so that the decreased amount of functional chondroblasts enhance prechondroblast replication. Similar to the effect of thyroxine.
  • 53. TWIN BLOCK Alters the occlusal inclined planes. 70˚ inclined planes alter the sensory engram and provide a horizontal component of force.
  • 54. L.S.U. OR HERREN ACTIVATOR Acts when appliance is not worn. Action not mediated to through the LPM but through the retrodiscal pad. Shortening of the LPM when the appliance is worn compared to other muscles. A new sensory engram is produced. The mandible closes in a more anterior position.
  • 55. EFFECT OF CHIN CUP THERAPY Retropulsion of the mandible results in reduction in number of dividing cells. Dividing cells if any are found anteriorly. Resulting in anterior Growth rotation and decreased mandibular Length.
  • 56. CLINICAL IMPLICATIONS • Principle of optimality of function:- less relapse tendency if post orthodontic treatment muscular activity produces a lower deviation signal. • Removal of functional appliances when growth is complete. • If removed when growth not complete then we need proper intercuspation.
  • 57. • First group : full time , second group: part time . • Proper functioning of LPM and RDP is important for growth – parent counselling should be done properly. • Sensory engram is poorly developed in younger children. • Utilization of high hormonal activity at puberty.
  • 58. CONSIDERATIONS OF SERVOSYSTEM THEORY Growth Rotations of the Mandible Alveolar Bone Turnover Rate
  • 59. BIFURCATION Topologic Representation of increasing Hormone levels (testosterone or STH- stomatomedin) resulting in supplementary growth of the mandible combined with lengthening of the maxilla as modulated by the comparator of the servosystem (cuspal relief). Experimental results are expressed in terms of
  • 60. PETROVIC’S GROWTH CATEGORIES Growth Inequality of Bases 1 : Mandible equal to maxilla 2: Mandible smaller than maxilla 3 : Mandible greater than maxilla Rotation of the Mandible R : Neutral P: Posterior rotation of mandible A: Anterior Rotation of Mandible Posteroanterior State N: Normal D: Distal M: Mesial Vertical State N: Normal OB: Open Bite DB: Deep Bite
  • 61.
  • 62. LEVEL -1 Cell and molecular Biology Level 70% 3% 25% Mandible less than Maxilla Mandible greater than Maxilla Mandible equal to Maxilla Quantitative determination of difference between maxilla and mandible.
  • 63. LEVEL -2 Partly on Respiration Phonation & Deglutition Anterior Posterior Neutral Relates to the Growth rotation and growth inclination of both maxilla and mandible
  • 64. LEVEL -3 Unstable occlusion and Functional Discontinuity Distal Mesial Normal Based on the occlusal relationship
  • 65. GROWTH ROTATIONS OF MANDIBLE Morphogenetic Rotations Positional Rotations The Change in the Shape of Mandible The Change in the Position of Mandible in relation to the Adjacent Structures Lavergene & Gasson (1977)
  • 66. ALVEOLAR BONE TURN OVER RATE Tissue level Growth Potential : Level of subperiosteal ossification rate and the level of alveolar bone turnover rate Tissue level Growth Responsiveness: The degree of augmentation of the alveolar bone turnover resulting from orthodontic treatment.
  • 67. AUXOLOGIC GROUPS Six auxologic categories of the mandible. Depends on: 1. tissue level growth potential 2. Tissue level Growth responsiveness to orthodontic, orthopedic and functional appliances. Helps define the biologic inter- individual variation of growing mandible. Clinicians must give importance to tissue level growth responsiveness than
  • 68. FAILURE OF SERVOSYSTEM TO CONTROL GROWTH Before development of Occlusion Sensory engram not developed Servosystem does not operate Genetic influence of mandibular Growth Anodontia After Development of Occlusion :- Sensory Engram forms Peripheral Comparator Control Minimize possible deviation to achieve stable occlusion. Peripheral Comparator Faulty- Caries, Mutilated Dentition Discrepancy between rotation pattern (Anterior or Posterior) and location of Comparator.
  • 69. DRAWBACKS The author places a lot of importance on the role of hormones in controlling growth. The peripheral comparator, the occlusion, itself is unstable.  According to this theory, an end on relation is a Repeller. This theory places a lot of importance on condyle as growth center. If condylar cartilage is lost, growth should seize. But some studies done on Scandinavia show that this does not happen.
  • 70. EVIDENCES AGAINST THE THEORY Goret – Nicaise, Awn (1983) - Resection of LPM – Fails to diminish condylar Growth. Whetten and Jhonston (1985) – bilateral condylectomy and unilateral LPM in rats – same growth on both sides. Das, Myer & Sicher ( 1980) – Occlusion remained unaffected in condylectomy studies.
  • 71. CONCLUSION While we may no longer seek a single synthesizing theory for all of craniofacial growth, we now have, because of petrovic’s work, a convenient model & a language by which we can describe and relate growth activities to one another, thus obviating any need for another paradigm. The cybernetic theory of facial growth and the crucial - topologic concept of structural and functional stability and instability are highly useful in a systematic and increasingly computerized approach to clinical situations.
  • 72. REFERENCES • GRABER, PETROVIC, RAKOSI. DENTOFACIAL ORTHOPAEDICS AND FUNCTIONAL APPLIANCES, 2ND EDITION, 1917. • ZHOU, Z.; LUO, S. (1998-05-01). "[DIFFERENTIAL EXPRESSION OF IGF-I AND ITS MRNA IN MANDIBULAR CONDYLAR CARTILAGE OF RAT--DIRECT EVIDENCE FOR SERVOSYSTEM THEORY OF FACIAL GROWTH]". HUA XI KOU QIANG YI XUE ZA ZHI = HUAXI KOUQIANG YIXUE ZAZHI = WEST CHINA JOURNAL OF STOMATOLOGY. 16 (2): 164–165. ISSN 1000- 1182. PMID 12214426. • HTTPS://WWW.SCRIBD.COM/DOCUMENT/383886681/PETROVIC. • ROLE OF THE LATERAL PTERYGOID MUSCLE AND MENISCOTEMPOROMANDIBULAR FRENUM IN SPONTANEOUS GROWTH OF THE MANDIBLE AND IN GROWTH STIMULATED BY THE POSTURAL HYPERPROPULSOR J.J. STUTZMANN , A.G. PETROVIC DOI:HTTPS://DOI.ORG/10.1016/0889-5406(90)70110-X. • HTTPS://PHAIDRABG.BG.AC.RS/OPEN/O:21881