The newsletter provides information from the International Senologic and Oncologic Scientific Community (ISOCS). It highlights recent literature on breast cancer screening and treatment approaches. It also announces upcoming conferences and workshops. The newsletter aims to connect medical specialists around the world to discuss cancer research and improve patient care.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
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Literature Selection
z Venturini E et al.: Tailored Breast Cancer Screening Program with Microdose Mammography, US, and
MR Imaging: Short-term Results of a Pilot Study in 40-49-Year-Old Women, Radiology. 2013 Apr 11.
[Epub ahead of print]
z Girardi V et al.: Breast ultrasound in 22,131 asymptomatic women with negative mammography,
Breast. 2013 Apr 1 [Epub ahead of print]
z Nelson H et al.: Use of medications to reduce risk for primary breast cancer: a systematic review for
the u.s. Preventive services task force, Ann Intern Med. 2013 Apr 16;158(8):604-14
z Heemskerk-Gerritsen BA et al.: Substantial breast cancer risk reduction and potential survival benefit
after bilateral mastectomy when compared with surveillance in healthy BRCA1 and BRCA2 mutation
carriers: a prospective analysis, Ann Oncol. 2013 Apr 10. [Epub ahead of print]
z Li J et al.: Mammographic Density Reduction Is a Prognostic Marker of Response to Adjuvant
Tamoxifen Therapy in Postmenopausal Patients With Breast Cancer, J Clin Oncol. 2013 Apr 22.
[Epub ahead of print]
z Lazzeroni M et al.: Tailoring treatment for ductal intraepithelial neoplasia of the breast according to
Ki-67 and molecular phenotype, Br J Cancer. 2013 Apr 11 [Epub ahead of print]
z Zagouri F et al.: Intrathecal administration of trastuzumab for the treatment of meningeal
carcinomatosis in HER2-positive metastatic breast cancer: a systematic review and pooled analysis,
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3. Breast Cancer Res Treat. 2013 Apr 16. [Epub ahead of print]
z Chen X et al.: Analysis in early stage triple-negative breast cancer treated with mastectomy without
adjuvant radiotherapy: Patterns of failure and prognostic factors, Cancer. 2013 Apr 10. doi:
10.1002/cncr.28085. [Epub ahead of print]
Questions and Answers
z Breast Cancer Workshop Summary - with Cynthia Ma, Washington University School of Medicine͕ St. Louis,
MO, USA
Discussion
z Even in women with breast tumours of excellent prognosis, local recurrence after conservative surgery
without adjuvant therapy is very high - Share your opinion on LinkedIn
Fragments of History
z 1981 - Umberto Veronesi, National Cancer Institute, Milan, Italy: A number of different factors may explain the
progressive development of new procedures for conservative treatment of breast cancer. The first factor is a
better understanding of the natural history of breast cancer and of the fact that the results of treatment are
influenced more by distant spread when it occurs than by local or regional control of the disease. The second
is the discovery of increasing numbers of cancers of minimal dimensions by means of new diagnostic
techniques, especially mammography. The third is the more pressing demand for less mutilating procedures
and the increasing requests from patients to be informed of the various possible treatments, including the
conservative techniques. Finally, there is a widespread belief that if a conservative treatment could be offered
to women with early breast cancer, it would represent a tremendous tool for publicizing self-examination of the
breasts and alertness in seeking medical advice at the first appearance of a lump in the breast. (Veronesi U
et al.: Comparing radical mastectomy with quadrantectomy, axillary dissection, and radiotherapy in
patients with small cancers of the breast, N Engl J Med.1981Jul 2;305(1):6-11)
Calendar of Events
z 5th IMPAKT Breast Cancer Conference, May 2-4, 2013, Brussels, Belgium
z Precision Medicines in Breast Cancer, May 9-10, 2013, London, UK
z 15th Milan Breast Cancer Conference, June 20-21, 2013, Milan, Italy
z 3rd World Congress on Cancer Science Therapy, October 21-23, 2013, San Francisco, CA, USA - in
Partnership with Senology
z 9th Meet the Professor. Advanced International Breast Cancer Conference (AIBCC), November 11-13,
Padova, Italy - under the Patronage of Senology
z Update in Breast Imaging, 22-23 November, Ostend, Belgium
Literature Selection
z Su VY et al.: Amiodarone and the risk of cancer: A nationwide population-based study, Cancer. 2013
Apr 8. doi: 10.1002/cncr.27881. [Epub ahead of print]
z Raaschou P et al.: Rheumatoid arthritis, anti-tumour necrosis factor therapy, and risk of malignant
melanoma: nationwide population based prospective cohort study from Sweden, BMJ. 2013 Apr
8;346:f1939
z Xing M et al.: Association between BRAF V600E mutation and mortality in patients with papillary
thyroid cancer, JAMA. 2013 Apr 10;309(14):1493-501
z Dorffel W et al.: Treatment of Children and Adolescents With Hodgkin Lymphoma Without
Radiotherapy for Patients in Complete Remission After Chemotherapy: Final Results of the
Multinational Trial GPOH-HD95, J Clin Oncol. 2013 Apr 20;31(12):1562-8
Editorial
z Core needle biopsy for thyroid nodules with previous non-diagnostic fine needle aspiration, Jung
Hwan Baek, Department of Radiology and Research Institute of Radiology, University of Ulsan College of
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ZZZVHQRORJRUJ
Medicine, Asan Medical Center, Seoul, Korea
Core needle biopsy (CNB) for thyroid nodules with previous non-diagnostic fine needle aspiration (FNA)
results showed a low incidence (1.3%, 2/155) of non-diagnostic results. CNB also showed high diagnostic
values for neoplasm and malignancy. In addition, CNB could prevent unnecessary diagnostic surgery in 96%
(22 of 23) of patients with repeated nondiagnostic FNA results. This result suggests that CNB is a viable
method of choice for the reliable diagnosis of thyroid nodules for which previous FNA results were
nondiagnostic
(Commentary on: Yeon JS et al.: Thyroid Nodules with Initially Nondiagnostic Cytologic Results: The
Role of Core-Needle Biopsy, Radiology 2013 Mar 22 [Epub ahead of print])
Questions and Answers
z Kidney Cancer Workshop Summary - with Sumanta Kumar, City of Hope, Duarte, CA, USA
z Lung Cancer Workshop Summary - with Jared Weiss, University of North Carolina, Chapel Hill, NC, USA
z Stem Cell Workshop Summary - with Anthony Stein, City of Hope, Duarte, CA, USA
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