Self-regulation skills are developing in infants and toddlers, including shifting attention, self-soothing, focusing attention, adjusting behavior to achieve goals, briefly delaying gratification, labeling feelings, and turning to adults for help with strong feelings. Caregivers support self-regulation development through co-regulation, which includes building warm relationships, coaching self-regulation skills, and structuring the environment. Interventions for infants and toddlers focus on co-regulation alone or combine co-regulation and skills instruction.