ءئئء

1. 1
‫اﻟ‬
‫ﻤﺴﺘﻮى‬
:
3
‫ﻋ‬
‫ﺗﺠﺮﯾﺒﯿﺔ‬ ‫ﻠﻮم‬
‫ﺳﺎﻋ‬ : ‫اﻟﻤﺪة‬
‫ﺔ‬
‫اﻟﻔﺮض‬
‫اﻟﺜﺎﻧﻲ‬
‫ﻟﻠﻔﺼﻞ‬
‫اﻻول‬
‫اﻟﻄﺒﻴﻌﻴﺔ‬‫اﻟﻌﻠﻮم‬‫ﻓﻲ‬
‫اﻟﺪراﺳﻴﺔ‬‫اﻟﺴﻨﺔ‬
2016
/
2017
‫اﻟﺘﻤﺮﯾﻦ‬
02
:
‫اﺳﺎﺳﯿﺎ‬ ‫دورا‬ ‫اﻻﻧﺰﯾﻤﺎت‬ ‫ﺗﻠﻌﺐ‬
‫ﻗ‬
‫اﻟﺨﻠ‬ ‫اﻟﻨﺸﺎط‬ ‫ﻲ‬
‫ﻮي‬
‫ﺗﺮﺑﺴﯿﻦ‬ ‫اﻟﻜﯿﻤﻮ‬ .
‫اﻟﺘﺮﯾﺒﺴﻦ‬ ‫و‬
‫اﻧﺰﯾﻤ‬
‫ﯿﻦ‬
‫ﻣﻮﺟ‬
‫ﻮ‬
‫د‬
‫ﯾﻦ‬
‫اﻟﻌﺼﺎرة‬ ‫ﻓﻲ‬
‫ﯾﺤﻔﺰ‬ ‫ﺣﯿﺚ‬ ‫اﻟﺒﻨﻜﺮﯾﺎﺳﯿﺔ‬
‫اﻟﻜﯿﻤﻮﺗﺮﺑﺴﯿﻦ‬
‫اﻟﻤﻮﺿﺢ‬ ‫اﻟﺘﻔﺎﻋﻞ‬
‫ﻣﺮاﺣﻠﮫ‬
‫اﻟﻮﺛﺒﻘﺔ‬ ‫ﻓﻲ‬
01
:‫ﻣﻼﺣﻈﺔ‬
‫اﻟﻤﺠﻤﻮﻋﺔ‬
B
‫ﺗ‬
‫اﻻﺣﻤﺎض‬ ‫ﻣﻦ‬ ‫ﺘﻜﻮن‬
Ser295.His57.Asp102
1
-
‫اﻻﺟﺰاء‬ ‫ﺗﻤﺜﻞ‬ ‫ﻣﺎذا‬
A+B
‫؟‬ ‫ﻣﻌﺎ‬
2
-
‫اﻟﻮﺛﯿﻘﺔ‬ ‫ﻋﻠﻰ‬ ‫ﻣﻌﺘﻤﺪا‬ ‫اﻻﻧﺰﯾﻢ‬ ‫ﻋﻤﻞ‬ ‫اﻟﯿﺔ‬ ‫اﺷﺮح‬
01
3
-
‫؟‬ ‫اﻻﻧﺰﯾﻢ‬ ‫ﻟﮭﺬا‬ ‫اﻟﻔﻌﺎل‬ ‫اﻟﻤﻮﻗﻊ‬ ‫ﻧﺸﺎط‬ ‫ﯾﺨﺺ‬ ‫ﻓﯿﻤﺎ‬ ‫ﺗﺴﺘﻨﺘﺞ‬ ‫ﻣﺎذا‬
4
-
‫اﻻﻣ‬ ‫اﻻﺣﻤﺎض‬ ‫ان‬ ‫اذاﻻﻋﻠﻤﺖ‬
‫ﯿﻨﯿﺔ‬
Ser295.His57.Asp102
‫اﻧﺰﯾﻢ‬ ‫ﻋﻨﺪ‬ ‫ﻣﻮﺟﻮدة‬
‫اﻟﺘﺮﺑﺴﯿﻦ‬
‫اﻟﺬي‬
‫اﻟﺤﻤﺾ‬ ‫ﯾﺴﺘﮭﺪف‬
‫اﻟﻠﯿﺰﯾﻦ‬ ‫اﻻﻣﯿﻨﻲ‬
‫أ‬
-
‫ﺗﻮاﺟﺪ‬ ‫ﻓﺴﺮ‬
‫اﻟﺘﺮﺑﺴﯿﻦ‬ ‫ﻋﻨﺪ‬ ‫اﻻﺣﻤﺎض‬ ‫ھﺬه‬
5
-
‫اﻋﺘﻤﺎدا‬
‫ﻋﻠﻰ‬
‫ﻧﻮ‬
‫ع‬
‫اﻟﻤﻜ‬ ‫اﻻﻣﻨﯿﺔ‬ ‫اﻻﺣﻤﺎض‬ ‫ﻧﻮع‬ ‫اﻗﺘﺮح‬ ‫اﻟﻤﺴﺘﮭﺪف‬ ‫اﻻﻣﻨﻲ‬ ‫اﻟﺤﻤﺾ‬
‫ﻮ‬
‫ﻟﻠﻤﻨﻄﻘﺔ‬ ‫ﻧﺔ‬
A
‫اﻻﻧﺰﯾﻤﯿﻦ‬ ‫ﻣﻦ‬ ‫ﻛﻞ‬ ‫ﻓﻲ‬
6
-
‫اﻟﻤﻨﻄﻘﺔ‬ ‫ﺳﻢ‬
A
‫اﻟﻤﺠﻤﻮﻋﺔ‬ ‫و‬
B
‫اﻟﺘﻌﻠﯿﻞ‬ ‫ﻣﻊ‬
7
-
‫اﻟﯿﻚ‬
‫اﻻﺗﻲ‬ ‫اﻟﺒﺒﺘﯿﺪ‬
NH2-Asn-Ile-Lys-His-Leu-Gln-Phe-Val-Ala-COOH
‫أ‬
-
‫اﻟﺘﺤﻠﻞ‬ ‫ﻧﻮاﺗﺞ‬ ‫ﺣﺪد‬
‫اﻟﻨﮭﺎﺋﯿﺔ‬
‫اﻟﺒ‬ ‫ﻣﻌﺎﻣﻠﺔ‬ ‫ﺗﻢ‬ ‫اﻧﮫ‬ ‫ﻋﻠﻤﺎ‬
‫ﺒ‬
‫ﺘ‬
‫ﯿ‬
‫اﻟﺴﺎﺑﻖ‬ ‫ﺪ‬
‫ﺑﺈﻧﺰﯾﻢ‬
‫اﻟﺘﺮﺑﺴﯿﻦ‬ ‫ﺛﻢ‬ ‫اﻟﻜﯿﻤﻮﺗﺮﺑﺴﯿﻦ‬
‫ﻓﻲ‬
‫ﺣﯿﻮي‬ ‫ﻣﻔﺎﻋﻞ‬
1
-
‫ﺑﺪرﺟﺔ‬
‫ﺣﺮارة‬
37
°
‫و‬
PH=2
2
-
‫ﺣﺮارة‬ ‫درﺟﺔ‬
37
°
‫ﻓﻲ‬
PH =8
‫اﻟﻮﺛﯿﻘﺔ‬
01
phe
H2O

2. 2
8
-
‫ا‬ ‫اﻟﺘﺨﺼﺺ‬ ‫ﺑﯿﻦ‬ ‫اﻟﻌﻼﻗﺔ‬ ‫ﺣﺪد‬ ‫ﺳﺒﻖ‬ ‫ﻣﻤﺎ‬
‫ﻟﻮ‬
‫ﻟﻺﻧﺰﯾﻢ‬ ‫ظﯿﻔﻲ‬
‫وﺑﯿﻨﺘﮫ‬
‫ﻓﯿﮫ‬ ‫ﯾﻌﻤﻞ‬ ‫اﻟﺬي‬ ‫اﻟﻄﺒﯿﻌﻲ‬ ‫اﻟﻮﺳﻂ‬ ‫و‬