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Running head: 3D PRINTED AND CONVENTIONAL
PROSTHETIC LIMBS 1
3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS
2
SEE MY NOTES BELOW IN CAPS
ANY SAFE ASSIGN PROBLEMS? OK
GRADE FOR THIS DRAFT -- PAPER GRADE / grammar grade
D / B-
ACADEMIC FORMATTING
References page
NEEDS WORK -- LOW PASS
In-text citations
NOT ENOUGH CITING --
BODY PARAGRAPHS
Synthesized
NOT ACCOMPLISHED -- NO PASS
Unified
NEEDS WORK -- NOT IDENTIFYING BP THEMES
CLEARLY
Coherency
NO DEVELOPMENT OF BP THEMES
Transitions between BPs
UNCLEAR CONNECTIONS OF ARGUMENTS -- ALSO YOU
ARE MAKING AN ARGUMENT RATHER THAN
INVESTIGATING A QUESTION
Clarity of the writing
WITH SO LITTLE DEVLEOPMENT OF IDEAS IT IS
DIFFICULT TO KNOW WHAT THE SPECIFIC PURPOSE OF
THIS SECTION IS
Answered Section Question?
NOT ACCOMPLISHED WITH ANY DETAIL
Grammar - SEE RED FOR MISTAKES
FOLLOW-UP WORK After completing the drafts of the first
andsecond sections of your paper send—via attachment to an
email—the paraphrased selections which the instructor
BOLDED. Use the Paraphrase Check Work form explained in
Module #10 webinar to share your bolded paraphrase and the
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_____________________________________________________
_______________________________________________
3D Printed and Conventional Prosthetic Limbs
Name: Chanyez Chamberlain
Institution: York College
Date: 4/19/2018
INSERT PAGE BREAK BETWEEN COVER PAGE AND BODY
OF THE PAPER
MAIN QUESTION??? >>> Can 3D printed limbs be a more
effective alternative to conventional prosthetic limbs?
FOLLOW ARE NOT THE THREE SECTION QUESTIONS AS
REQUIRED
1. Can 3D printed prosthetic limbs be more cost effective than
conventional prosthetic limbs? FOCUS HERE IS ONLY ON
COST --
2. What is the cost of material for creating 3D printed limbs?
3. What is the cost of material for creating conventional
prosthetic limb?
4. How does the cost of shipping 3D printed limbs versus
conventional prosthetic limbs compare?
5. What is the accessibility of each for low-income families?
MUST HAVE ONLY THREE SECTION QUESTIONS - NOT
THE COMMON THEMES OF EACH BP IN THIS SECTION --
PLEASE REFER TO EXAMPLES
Can 3D printed prosthetic limbs be more
cost effective than conventional prosthetic limbs? USE TITLE
CASE
Technology creates a higher level of engagement where it is
possible to achieve an improved level of effectiveness under
which it is possible to improve the lives of individuals.
<<,THIS IS CONFUSING -- NOT SURE WHAT THE POINT IS
OR WHAT IT RELATES TO -- PLEASE CONSIDER RE-
WRITING WHAT IS UNDERLINED ?>>>The conventional
hypothetic limb is an artificial device, which replaces a missing
leg, which might be lost in different ways such as trauma,
congenital conditions or disease. They have a fundamental
purpose where they are aimed at restoring standard functionality
of an individual limb. The need for a more efficient limb has led
to a more significant technology innovation where there is need
to achieve a higher level of engagement based on the need for a
transformative technology. <<,THIS NEEDS TO BE SHOWN --
HAS NOT AT THIS EARLY STAGE OF THE PAPER
Printing 3D limbs have to provide a very different perspective
where patients in need of artificial limbs can be fitted. 3D legs
are more efficient, cost-effective and have less detrimental an
individual health and well-being. WHERE DO YOU DEFINE
WHAT THIS TECHOLOGY IS -- HOW IT DEVELOPED --
AND WHETHER THERE IS A NEED FOR IT -- THAT THERE
IS A PROBLEM THAT NEEDS TO BE SOLVED -- SHOULD
COME FIRST IN THIS PAPER
What is the cost of material for creating 3D printed limbs?
SPELL OUT TERM>>> PROFITABLE IS NOT THE SAME
AS COST EFFECTIVE FOR THE PATIENT >>> 3D printed
prosthetic limbs are more profitable than conventional
prosthetic limbs. The cost aspect that is considered in this case
involves the cost of production, purchase, and transportation.
The 3D printed prosthetic limbs is a significant innovation,
which has sought to create highly modernized limbs, which can
help an individual carry out their activities without considerable
challenge. The 3D printed limbs are particular to each patient
since there is need to ensure that they are compatible with the
system of the patient to achieve a higher level of efficiency
(Ventola, 2014). NO FOCUS HERE -- RELATES TO MANY
DIFFERENT THEMES -- IS NOT SYNTHESIZED -- NOT
DEVELOPED -- NO PASS BP
1. PROFITABLITY
2. PRODUCTION COST
3. COST TO THE PATIENT
4. COST OF TRANSPORTING
5. IMPORTANT INNOVATION IN THIS TECHOLOGY --
6. DESIGNEDN FOR EACH PATIENT
What is the cost of material for creating conventional prosthetic
limb?
The cost of material for creating a conventional prosthetic limb
is very high and thus fewer individuals can afford the
conventional limbs since they involve many steps, which
consume a lot of time during production time and therefore has
a significant influence on the overall production cost for the
traditional prosthetic limbs. The development of a single
prosthetic limb based on the traditional approaches takes
approximately a week. THERE IS NOT SUPPORT FOR THIS
THEME -- THAT CONVENTIONAL ARTIFICIAL LIMBS ARE
TOO COSTLY -- NO PROOF OF THIS CONTENTION - NOT
SURE WHAT THE PURPOSE OF THIS BP IS -- NEEDS
WORK -- NO PASS BP
How does the cost of shipping 3D printed limbs versus
conventional prosthetic limbs compare?
The prosthetic need to be built and sized manually and thus to
have mass production, there is a need for high labor, which
automatically leads high cost of production where the cost of
production is passed to patients, which limit their ability to
create a higher engagement. <<<THIS IS AN OVERLY LONG
TOPIC SENTENCE -- HOW CAN YOU SEE THIS THEME
SIMPLY The cost of conventional prosthetic limb varies based
on the type of the limb that is purchased. The cost varies from
$5,000 and 100,000 for an advanced myoelectric arm controlled
by muscle movements (Diment, Bergmann & Thompson, 2017).
NO DEVELOPMENT -- NO SYNTHESIS - NO PASS BP
What is the accessibility of each for low-income families?
The 3D printed prosthetic limbs cut the cost and production
time significantly. The 3D printed prosthetic limbs are expected
to be produced at 80% faster rate than the conventional
prosthetic limbs from one week to 1.5 days and developed
efficiently with specific adaptability to specific patients. A
printed 3D printed prosthetic limbs costs approximately $20,
which is a tiny fraction of the total cost of conventional
prosthetic limb, which costs up to $100,000. The 3D printed
limbs are very useful based on high-level technology, which is
essential in deciding its influence on the many patients who are
in need of prosthetic limbs (Laszczak et al., 2015). NO
SYNTHESIS -- LITTLE DEVELPMENT OF THIS BP THEME -
-
UNCLEAR WHAT THIS TOPIC SENTENCE MEANS --
WRITE CLEARLY AND DIRECTLY SO THAT YOUR
READER UNDERSTAND THE TOPIC SENTENCE OF EACH
BP >>> The low cost of 3D printed limbs has created a
favorable environment where they are highly engaged access
difference social classes including low-income families who can
afford a 3D printed prosthetic limb. The cost when taking into
consideration the training on how to use is still manageable and
thus creates a higher level of engagement across different
countries. NO PASS BP -- NOT SCCUDy
There is need to focus on 3D printed limbs based on the high
degree of efficiency and cost effectiveness which ensures that
everyone who requires prosthetic limbs can get them at a very
affordable cost. A more significant engagement provides a
profoundly transformed focus where there is need to improve
services delivery within the development of prosthetic limbs.
INSERT PAGE BREAK -- DOUBLE SPACE THROUGHOUT
References
Diment, L., Bergmann, J., & Thompson, M. (2017). 3D printed
upper-limb prostheses lack randomized controlled trials: a
systematic review. INCOMPLETE
Laszczak, P., Jiang, L., Bader, D. L., Moser, D., & Zahedi, S.
(2015). Development and validation of a 3D-printed interfacial
stress sensor for prosthetic applications. Medical Engineering
and Physics, 37(1), 132-137. MISSING BIBLIO INFO
Ventola, C. L. (2014). Medical applications for 3D printing:
current and projected uses. Pharmacy and Therapeutics, 39(10),
704. MISSING INFO
Cyborg beast: a low-cost 3d-printed prosthetic
hand for children with upper-limb differences
Zuniga et al.
Zuniga et al. BMC Research Notes (2015) 8:10
DOI 10.1186/s13104-015-0971-9
Zuniga et al. BMC Research Notes (2015) 8:10
DOI 10.1186/s13104-015-0971-9
RESEARCH ARTICLE Open Access
Cyborg beast: a low-cost 3d-printed prosthetic
hand for children with upper-limb differences
Jorge Zuniga1*, Dimitrios Katsavelis1, Jean Peck2, John
Stollberg3, Marc Petrykowski1, Adam Carson1
and Cristina Fernandez4
Abstract
Background: There is an increasing number of children with
traumatic and congenital hand amputations or
reductions. Children's prosthetic needs are complex due to their
small size, constant growth, and psychosocial
development. Families’ financial resources play a crucial role in
the prescription of prostheses for their children,
especially when private insurance and public funding are
insufficient. Electric-powered (i.e., myoelectric) and
body-powered (i.e., mechanical) devices have been developed to
accommodate children’s needs, but the cost of
maintenance and replacement represents an obstacle for many
families. Due to the complexity and high cost of
these prosthetic hands, they are not accessible to children from
low-income, uninsured families or to children from
developing countries. Advancements in computer-aided design
(CAD) programs, additive manufacturing, and image
editing software offer the possibility of designing, printing, and
fitting prosthetic hands devices at a distance and
at very low cost. The purpose of this preliminary investigation
was to describe a low-cost three-dimensional
(3D)-printed prosthetic hand for children with upper-limb
reductions and to propose a prosthesis fitting
methodology that can be performed at a distance.
Results: No significant mean differences were found between
the anthropometric and range of motion measurements
taken directly from the upper limbs of subjects versus those
extracted from photographs. The Bland and Altman
plots show no major bias and narrow limits of agreements for
lengths and widths and small bias and wider limits of
agreements for the range of motion measurements. The main
finding of the survey was that our prosthetic device
may have a significant potential to positively impact quality of
life and daily usage, and can be incorporated in
several activities at home and in school.
Conclusions: This investigation describes a low-cost 3D-printed
prosthetic hand for children and proposes a
distance fitting procedure. The Cyborg Beast prosthetic hand
and the proposed distance-fitting procedures may
represent a possible low-cost alternative for children in
developing countries and those who have limited access to
health care providers. Further studies should examine the
functionality, validity, durability, benefits, and rejection rate
of this type of low-cost 3D-printed prosthetic device.
Keywords: 3D printing, Computer-aided design, Low-cost
prosthesis, Custom-made prosthesis, Prosthesis
for children
* Correspondence: [email protected]
1Department of Exercise Science and Pre Health Professions,
Creighton
University, Omaha, NE 68178, USA
Full list of author information is available at the end of the
article
© 2015 Zuniga et al.; licensee BioMed Central. This is an Open
Access article distributed under the terms of the Creative
Commons Attribution License
(http://creativecommons.org/licenses/by/4.0), which permits
unrestricted use, distribution, and
reproduction in any medium, provided the original work is
properly credited. The Creative Commons Public Domain
Dedication waiver
(http://creativecommons.org/publicdomain/zero/1.0/) applies to
the data made available in this article,
unless otherwise stated.
mailto:[email protected]
http://creativecommons.org/licenses/by/4.0
http://creativecommons.org/publicdomain/zero/1.0/
Zuniga et al. BMC Research Notes (2015) 8:10 Page 2 of 8
Background
Children’s prosthetic needs are complex due to their
small size, constant growth, and psychosocial develop-
ment [1]. Familial financial resources play a crucial role
in prescription of prostheses for children, especially when
private insurance and public funding are insufficient [1].
Most upper-limb prostheses include a terminal device,
with the objective to replace the missing hand or fingers.
The cost of a body-powered prosthetic hand ranges from
$4,000 to $20,000; depending on the mode of control,
these devices require extensive fitting procedures to de-
velop the terminal device and often include a complex
system of cables and harnesses [2]. Electric-powered
units (i.e., myoelectric) and mechanical devices (i.e., body-
powered) have been improved to accommodate children’s
needs, but the cost of maintenance and replacement rep-
resents an obstacle for many families. Voluntary-closing
upper-limb prosthetic devices are more suitable for chil-
dren [1,3] and play a crucial role in improving gross motor
development [1]. Currently, the most cost-effective option
for pediatric populations is a passive prosthetic hook [1];
although functional, these devices have a high rejection
rate, in part due to an unacceptable cosmetic appearance
[4-6]. Most current prosthetics do not adapt to the normal
growth of children’s limbs and require constant visits to
health care providers for adjustments or replacement,
which may lead to abandonment [1,6].
There has been an increase in the number of children
born with congenital upper-limb deficiencies or ac-
quired traumatic amputations during the past two de-
cades [7-9]. It is estimated that, in the United States,
more than 32,500 children suffer from a major pediatric
amputation [8], and the Centers for Disease Control
and Prevention estimates that about 1,500 children are
born with upper-limb reductions in the United States
each year [9]. Worldwide estimates for upper-limb re-
ductions range from 4-5/10,000 to 1/100 live births [7].
There is a critical need for practical, easy-to-replace,
customized, aesthetically appealing, low-cost prosthetic
devices for children [10].
Figure 1 Prosthetic hand (Cyborg Beast). A: Top view (A1:
Tensioner dia
and B: Bottom view (B1: Forearm adjustable Velcro strap, B2:
Hand adjustab
Advancements in computer-aided design (CAD) pro-
grams, additive manufacturing, and open source image
editing software offer the possibility of designing, print-
ing, and fitting prosthetic hands and other assistive de-
vices at very low cost [11] (Figure 1). The development
of low-cost prosthetic devices with practical and easy fit-
ting procedures that can be performed at a distance would
have a significant clinical and social impact on children
around the world.
Research Purpose
The aim of this preliminary investigation was to briefly
describe a low-cost three-dimensional (3D)-printed pros-
thetic hand for children with upper-limb reductions and
to propose a prosthesis fitting methodology that can be
performed at a distance. We hypothesized that anthropo-
metric measurement of the upper limbs taken from pho-
tographs and processed by image editing software would
not differ from anthropometric measurements taken dir-
ectly on upper limbs.
Methods
Subjects
Eleven children (two girls and seven boys, 3 to 16 years
of age) with upper-limb reductions (one traumatic and
eight congenital) participated in this study and were fit-
ted with a low-cost 3D-printed prosthetic hand. Of the
11 participants, nine performed the laboratory visits and
two were distance participants. A comparison between
anthropometric measurements of the upper limbs taken
from photographs and those taken directly on the upper
limbs were reported for only nine local participants. In-
clusion criteria included boys and girls from 3 to 17 years
of age with unilateral carpus upper-limb reductions,
missing some or all fingers, and wrist range of motion of
the affected wrist greater than 20°. Exclusion criteria in-
cluded upper extremity injury within the past month
and any medical conditions that would contraindicate
the use of our prosthetic hand prototype, such as skin
abrasions and musculoskeletal injuries. The study was
l, A2: Lift nylon cords, A3: Chicago screws, A4: Tension
balance system)
le Velcro strap).
Zuniga et al. BMC Research Notes (2015) 8:10 Page 3 of 8
approved by the Creighton University Institutional Review
Board and all the subjects completed a medical history
questionnaire. All parents and children were informed
about the study and parents signed a parental permission
form. For children 6 to 16, an assent was explained by the
principal investigator and signed by the children and their
parents. Written informed consent from the parents was
also obtained in order to publish the images shown in the
present investigation. In addition, detailed safety guide-
lines were given to the parents regarding the use and care
of the prosthetic hand.
3D-printed prosthetic hand characteristics and usage
The low-cost 3D-printed prosthetic hand named “Cyborg
Beast” (Figure 1) was designed using a modeling software
program (Blender 7.2, Blender Foundation, Amsterdam,
Netherlands) and manufactured in the researcher’s labo-
ratory using desktop 3D printers (Makerbot Replicator
2X, Makerbot Industries, Brooklyn, NY, and Ultimaker 2,
Ultimaker B.V., Geldermalsen, The Netherlands). Elastic
cords placed inside the dorsal aspect of the fingers provide
passive finger extension. Finger flexion is driven by non-
elastic cords along the palmar surface of each finger and is
activated through 20-30° of wrist flexion. The result is a
composite fist (flexing the fingers towards the palm) for
gross grasp. The materials used for printing our prosthetic
hand are polylactide (PLA) plastic and acrylonitrile buta-
diene styrene (ABS). Other components of the prosthetic
hand include Chicago screws of various sizes, 1 mm lift
nylon cord, 1.5 mm elastic cord, Velcro, medical-grade
firm padded foam, protective skin sock, and a dial ten-
sioner system (Mid power reel M3, Boa Technology Inc.,
Denver, Colorado). The majority of these materials are
available at local hardware stores or online. The present
cost of materials is about $50 USD. The average time to
fully assemble the prosthetic hand design is approximately
2. 5 hours. The weight of a fully assembled hand at a
140% of its original size is 184.2 grams. A similar device
costs approximately $4,000 and weighs about 400 grams.
The Cyborg Beast prosthetic hand is well suited for ac-
tivities that involved the manipulation of light objects
Figure 2 Three photographs of upper limbs. A: wrist extension
(A1: non
and C: Top view (C1: Non-affected hand length, C2: Non-
affected hand wid
C5: Affected hand length, C6: Affected hand width, C7:
Affected forearm le
using lateral, power (composite), and spherical prehen-
sile patterns.
Justification for the design and use of the 3D-printed
prosthetic hand are low cost, easy usage, easy fitting,
easy assembly, and visually appealing to children. The
fitting procedures for the prosthetic hand require a few
simple anthropometric measures of both limbs (Figure 2)
to properly scale the prosthetic device. The files for the
design are available online on the National Institutes of
Health (NIH) 3D print exchange website (http://3dprint.
nih.gov/discover/3dpx-000524) and Thingiverse (http://
www.thingiverse.com/thing:261462). All families and
children participating in this study completed a short
survey. The survey was developed to estimate the impact
of this prosthetic device, including items related to qual-
ity of life, daily usage, and types of activities performed.
The survey has not been statistically validated, but pro-
vides useful information related to usage and perception
about improvements in quality of life. After approxi-
mately one to three months of using the prosthetic hand,
11 children and their parents reported some increases in
quality of life (four indicated this was significant and
seven indicated a small increase), while one indicated no
change. Nine children reported using the hand one to
two hours a day, three reported using the prosthetic hand
more than two hours, and one reported using the hand
only when needed. Furthermore, children reported using
the prosthetic hand just for fun (n = 10), for activities at
home (n = 9), to play (n = 6), for school activities (n = 4),
and to perform sports (n = 2).
Proposed distance-fitting procedure
The prosthetic hand (Figure 1) was designed to allow
easy fitting with minimal anthropometric measurement
requirements, which include hand length (tip of the
middle finger to center of the wrist joint, Figure 2C1and
C5), palm width (widest region of the palm above the
base of the thumb, Figure 2C2), forearm length (center
of the wrist joint to center of the elbow joint, Figure 2C3
and C6), forearm width at three-fourths (width of the
forearm at proximal three-fourths of the length of the
-affected, A2 affected), B: wrist flexion (B1: non-affected, B2:
affected),
th, C3: Non-affected forearm length, C4: Non-affected forearm
width,
ngth, and C8: Affected forearm width).
http://3dprint.nih.gov/discover/3dpx-000524
http://3dprint.nih.gov/discover/3dpx-000524
http://www.thingiverse.com/thing:261462
http://www.thingiverse.com/thing:261462
Zuniga et al. BMC Research Notes (2015) 8:10 Page 4 of 8
forearm proximal to the wrist, Figure 2C4 and C7), and
range of motion of the wrists (extension and flexion,
Figure 2A1 and A1). The proposed distance-fitting proced-
ure involves extracting all these required measurements
from three photographs of the upper limbs (Figure 2).
To compare the anthropometric measurements taken
directly from the subject’s upper limbs with those ex-
tracted from photographs, a trained occupational the-
rapist took the required anthropometric measurements
directly from the subject’s upper limbs using a standard
tape measure and goniometer. Three photographs of the
upper limbs were taken as shown in Figure 2. All pic-
tures included a ruler and were taken directly above the
arms and included the entire forearm up to the elbow.
To measure range of motion of the wrist, participants
extended (Figure 2A) and flexed (Figure 2B) their wrists
as far as possible. In addition, a reference line was drawn
over the participant’s wrist joint of the non-affected
hand (Figure 2C). An image editing program (ImageJ,
version 1.46, NIH) was used to assess hand length, palm
width, forearm length, forearm width at three-fourths,
and range of motion of the wrists for flexion and exten-
sion (Figure 2). All anthropometric measurements were
taken directly from the subject’s upper limbs and com-
pared to those extracted from photographs using an image
editing program. All measurements were expressed in
centimeters and calibrated using the ruler included in
the image.
Figure 3 Illustration of an image imported as plane and a
Cyborg be
After saving the images files with the calibrated mea-
surements, they were imported as planes in Blender
(Figure 3). Calibration of the metric scale on Blender
was performed by changing the default unit (meter) to
centimeters by adjusting the scale to 0.001. The image
plane was resized to match the size of the 1 cm back-
ground grid on Blender using the ruler on the imported
image plane. The accuracy of the calibrations was con-
firmed using the interactive ruler tool on Blender, per-
forming several measurements over the ruler included in
the image plane (Figure 3). After the image plane was cali-
brated, a sizing chart was used to estimate the predicted
size of the prosthetic hand expressed as a percentage of its
original size (Figure 4). MakerWare software (Makerbot
Industries, Brooklyn, NY) was used to size the prosthetic
hand to the desired scale (%) using the scaling function.
The sizing chart was developed to provide an easy method
to scale the prosthetic hand for the user with no previous
knowledge of CAD programs. For cases in which the
cubic regression equation (Figure 4) was not able to accur-
ately predict the correct size of the prosthetic hand due to
differences in hand morphology, customized adjustments
were made on Blender to ensure the proper fit. All the fit-
ting procedures were performed with the assistance of an
occupational hand therapist and a prosthetist. Thus, it is
recommended to include clinical experts in the process of
fitting the prosthetic device to avoid skin abrasions or
breakdown due to improper fit.
ast palm scale at 140% for a 16-year-old research participant.
Figure 4 Sizing chart for Cyborg Beast prosthetic hand.
Instructions: locate the child’s age in the bottom (X axis) and
follow the line to
the regression curve and then locate the intercepting line
corresponding to the scale % on the left side (Y axis). Example:
For a 5-year-old,
the scale % of the Cyborg Beast would be 118% (±1.44%). This
cubic regression equation was derived from a mixed sample of
11 children with
ages ranging from 3 to 16 years of age.
Zuniga et al. BMC Research Notes (2015) 8:10 Page 5 of 8
Statistical Analysis
Anthropometric Measurements
Seven separate two-way repeated measures ANOVAs
[2 × 2; hand (affected versus non-affected) × fitting pro-
cedures (direct versus photographs)] were performed to
analyze the data. In addition, the data have also been
presented using the method of Bland and Altman as
described by previous investigations [12-14]. Pearson
product–moment correlation coefficient was calculated
to examine the correlations between the difference and
the mean of the difference from the mean values shown
in the Bland and Altman plots. A p-value of ≤0.05 was
considered statistically significant for all comparisons.
Results
The results of the two-way repeated measures ANOVAs
showed no significant mean difference between the an-
thropometric measures taken directly on the subject’s
upper limbs and those taken from the photographs
(Table 1). There were no significant two-way interactions
Table 1 Mean (±SD) for anthropometric measures and range
Measurements Non-affected
Direct
Hand Length (cm) 13.83 ± 2.44
Palm Width (cm) 7.00 ± 1.20
Forearm Length (cm) 18.94 ± 3.88
Forearm Width (cm) 6.23 ± 0.85
Wrist Range of Motion Flexion (°) 76.00 ± 10.27
Wrist Range of Motion Extension (°) 76.44 ± 5.7
The results of the two-way repeated measures ANOVAs showed
no significant (p >0
the subject’s upper limbs and those taken from photographs.
There were no signifi
x fitting procedures. There was a significant main effect for
hand (affected versus n
versus photographs).
for repeated measures ANOVAs performed for hand ×
fitting procedures. There was a significant main effect,
however, for hand (affected versus non-affected), with no
significant main effect for fitting procedures (direct versus
photographs). When the relationship between scale of the
prosthetic hand (%) versus age (years) was analyzed, our
results indicated that the cubic model was the best-fit for
our sample (Figure 4). The main finding of the survey was
that our prosthetic device may have a significant potential
to positively impact quality of life and daily usage, and can
be incorporated in several activities at home and in school.
The Bland and Altman plots (Figure 5) show 95% limits of
agreements for the anthropometric measurements of the
affected hand and measures of range of motion. The aver-
age discrepancy (represented by a solid line in Figure 5)
for the lengths and widths of the hand and forearm re-
sulted in values close to zero, indicating no major bias.
The limits of agreement (represented by a dotted line in
Figure 5) are narrow and show that these measures tend
to be within 5 mm of each other. The range of motion
of motion of the wrists
Affected
Photographs Direct Photographs
13.44 ± 1.73 4.02 ± 1.07 4.25 ± 1.15
6.91 ± 0.95 4.50 ± 0.90 4.54 ± 0.66
18.94 ± 4.16 16.29 ± 3.41 16.69 ± 4.09
6.47 ± 1.12 5.57 ± 0.77 5.54 ± 0.59
75.33 ± 11.01 56.44 ± 13.15 59.76 ± 13.95
76.00 ± 6.96 45.67 ± 33.47 43.56 ± 33.29
.05) mean difference between the anthropometric measures
taken directly on
cant two-way interactions for repeated measures ANOVAs
performed for hand
on-affected), with no significant main effect for fitting
procedures (direct
Figure 5 Bland and Altman plots for anthropometric and range
of motion measurements taken directly from the subject’s upper
limbs
and those taken from photographs.
Zuniga et al. BMC Research Notes (2015) 8:10 Page 6 of 8
measurements, however, presented a small bias (average
discrepancy values greater than zero) and wider limits of
agreements, with about 10° difference between methods.
No trends were found and the correlations between the
difference and mean of the difference were not significant,
ranging from 0.04 to 0.53 (Figure 5).
Discussion
The results of the present investigation indicated that
there were no mean differences between anthropometric
measures taken directly from the subject’s upper limbs
and those extracted from photographs (Table 1). The
Bland and Altman plots (Figure 5) show no major bias
and narrow limits of agreements for lengths and widths
and small bias and wider limits of agreements for the
range of motion measurements. Furthermore, the survey
indicated that the prosthetic device may have a signifi-
cant potential to positively impact quality of life and
daily usage in several activities at home or school. The
fitting procedures of our prosthetic hand design require
minimal anthropometric measurements of the upper
limbs for proper scaling and fitting. Most fitting proce-
dures required for prosthetic hands include wrap cast-
ing using plaster bandages placed over the affected limb
[2]. More recently, 3D scanning has also been used for
the development of different type of prostheses and or-
thoses [11,15,16]. Casting procedures require the physical
presence of the individual needing the prosthetic hand
and the health care professional in the same physical loca-
tion, which may not be possible for patients living in rural
or isolated areas. 3D scanning procedures required so-
phisticated equipment and technical knowledge to per-
form the measurements. Furthermore, both techniques
require the patient to visit the health care facilities for
proper fitting procedures.
The results from the present investigation provide a
novel distance-fitting procedure for a low-cost 3D-printed
prosthetic hand for children with upper-limb differences.
Image editing software to extract information from digital
images has been used for a wide range of disciplines, in-
cluding molecular biology and archeology [17,18]. The
present investigation applied image editing techniques to
extract anthropometric data and 3D modeling applications
to develop a novel distance-fitting procedure. The recent
popularity and low cost of desktop 3D printers makes
the prosthetic hand described in the current investi-
gation readily accessible. The proposed distance-fitting
procedures can make this device accessible to a great
number of children in need of this type of device around
the globe. These procedures, however, must be performed
with caution, since inaccurate scaling or significant errors
in the measurements could affect the function or fitting
of the 3D-printed prosthetic hand. Overall, this low-
cost prosthetic hand and the ability to fit this device at
Zuniga et al. BMC Research Notes (2015) 8:10 Page 7 of 8
a distance represent a low-cost alternative for children
in developing countries and children from uninsured or
economically disadvantaged families.
Conclusion
This investigation provides a description of a low-cost
3D-printed prosthetic hand for children and proposes a
distance-fitting procedure. The Cyborg Beast prosthetic
hand and the proposed distance-fitting procedure repre-
sent a possible low-cost alternative for children in devel-
oping countries and those with little or no access to
health care providers. Our prosthetic device may have a
significant potential to positively impact quality of life
and daily usage. Further studies should examine the
functionality, validity, durability, benefits, and rejection
rate of this low-cost 3D-printed hand design.
Consent
All parents and children were informed about the study
and signed a parental permission. For children 6 to 16,
an assent was explained by the principal investigator
and signed by the children and their parents. Written
informed consent from the parents was obtained in or-
der to publish the images shown in the present inves-
tigation. Furthermore, detailed safety guidelines were
given to the parents regarding the use and care of the
prosthetic hand.
Abbreviations
3D: Three-dimensional; CAD: Computer-aided design; ABS:
Acrylonitrile
butadiene styrene; PLA: Polylactide; ANOVA: Analysis of
variance.
Competing interests
JZ is the designer of the prosthetic hand Cyborg Beast and
partially funded
this study with start-up funds. DK, JS, AC, and MP participated
in the
refinement and improvement of the prosthetic hand.
Author’s information
JZ is an Assistant Professor in the Department of Exercise
Science and Pre
Health professions at Creighton University, director of the 3D
Research &
Innovation Laboratory, and co-director of the Human Movement
Laboratory.
JZ is a member of the Association of Children’s Prosthetic-
Orthotic Clinics
and the American College of Sports Medicine.
DK is an Assistant Professor in the Department of Exercise
Science and Pre
Health professions and affiliated with the Physical Therapy
Department at
Creighton University. DK is a member of the American Society
of
Biomechanics and co-director of the Human Movement
Laboratory.
JP is an occupational therapist, certified hand therapist at CHI
Health
Creighton University Medical Center and an adjunct faculty at
the
Department of Occupational Therapy at Creighton University.
JS is a doctoral student from the Department of Occupational
Therapy at
Creighton University.
MP is an undergraduate student from the Department of
Exercise Science
and Pre Health Professions at Creighton University.
AC is an undergraduate student from the Department of
Exercise Science
and Pre Health Professions at Creighton University.
CF is an associate Professor of Pediatrics at Creighton
University. CF is
Children’s Physicians Medical Director-HEROES Program and
an Associate
Program Director for UNMC/Creighton University/Children’s
Hospital and
Medical Center.
Authors’ contributions
All the authors reviewed and contributed to the manuscript. JZ
was the
originator of the study concept and design, study methodology,
and
manuscript draft. DK, JP, JS, and MP were involved in data
collection. DK, JP,
and MP contributed to design improvements of the prosthetic
hand. MP
printed most of the parts of the prosthetic hands for the research
participants and performed substantial improvements. JZ, JP,
AC, and MP
assembled the prosthetic hands. DK performed part of the data
analysis.
All authors read and approved the final manuscript.
Acknowledgement
We would like to thank Richard Van As and Ivan Owen for their
contribution
in the development of the 3D-printed prosthetic hand named
Robohand.
Special thanks to all members of the online group “e-NABLE”
(http://
enablingthefuture.org/) for their feedback and constant support.
We also
would like to thank the parents and their children for
participating in our
study. Thanks to the students from the 3D Research &
Innovation Laboratory
at Creighton University (http://www.cyborgbeast.org/) who
helped with data
collection. This study was funded by the NASA Nebraska Space
Grant Office.
Author details
1Department of Exercise Science and Pre Health Professions,
Creighton
University, Omaha, NE 68178, USA. 2CHI Health Creighton
University Medical
Center, Omaha, NE 68131, USA. 3Department of Occupational
Therapy,
Creighton University, Omaha, NE 68178, USA. 4Children’s
Hospital and
Medical Center, Omaha, NE 68114, USA.
Received: 8 August 2014 Accepted: 31 December 2014
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AbstractBackgroundResultsConclusionsBackgroundResearch
PurposeMethodsSubjects3D-printed prosthetic hand
characteristics and usageProposed distance-fitting
procedureStatistical AnalysisAnthropometric
MeasurementsResultsDiscussionConclusionConsentAbbreviatio
nsCompeting interestsAuthor’s informationAuthors’
contributionsAcknowledgementAuthor detailsReferences
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Disability and Rehabilitation: Assistive Technology
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3D-printed upper limb prostheses: a review
Jelle ten Kate, Gerwin Smit & Paul Breedveld
To cite this article: Jelle ten Kate, Gerwin Smit & Paul
Breedveld (2017) 3D-printed upper limb
prostheses: a review, Disability and Rehabilitation: Assistive
Technology, 12:3, 300-314, DOI:
10.1080/17483107.2016.1253117
To link to this article:
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REVIEW
3D-printed upper limb prostheses: a review
Jelle ten Kate, Gerwin Smit and Paul Breedveld
Department of BioMechanical Engineering, Delft University of
Technology, Delft, The Netherlands
ABSTRACT
Goal: This paper aims to provide an overview with quantitative
information of existing 3D-printed upper
limb prostheses. We will identify the benefits and drawbacks of
3D-printed devices to enable improve-
ment of current devices based on the demands of prostheses
users.
Methods: A review was performed using Scopus, Web of
Science and websites related to 3D-printing.
Quantitative information on the mechanical and kinematic
specifications and 3D-printing technology used
was extracted from the papers and websites.
Results: The overview (58 devices) provides the general
specifications, the mechanical and kinematic
specifications of the devices and information regarding the 3D-
printing technology used for hands. The
overview shows prostheses for all different upper limb
amputation levels with different types of control
and a maximum material cost of $500.
Conclusion: A large range of various prostheses have been 3D-
printed, of which the majority are used by
children. Evidence with respect to the user acceptance,
functionality and durability of the 3D-printed
hands is lacking. Contrary to what is often claimed, 3D-printing
is not necessarily cheap, e.g., injection
moulding can be cheaper. Conversely, 3D-printing provides a
promising possibility for individualization,
e.g., personalized socket, colour, shape and size, without the
need for adjusting the production machine.
� IMPLICATIONS FOR REHABILITATION
� Upper limb deficiency is a condition in which a part of the
upper limb is missing as a result of a con-
genital limb deficiency of as a result of an amputation.
� A prosthetic hand can restore some of the functions of a
missing limb and help the user in perform-
ing activities of daily living.
� Using 3D-printing technology is one of the solutions to
manufacture hand prostheses.
� This overview provides information about the general,
mechanical and kinematic specifications of all
the devices and it provides the information about the 3D-
printing technology used to print the hands.
ARTICLE HISTORY
Received 18 July 2016
Revised 6 October 2016
Accepted 23 October 2016
KEYWORDS
3D-printing; hand;
prostheses; specifications;
upper limb
Introduction
Over the last 5 years, significant development has occurred in
3D-
printing of upper limb prostheses. All over the world people are
designing and printing new devices that can easily easy fit a
human arm. Scientific papers have been published regarding
research in the field of 3D-printed upper limb prostheses.[1–7]
People are developing prostheses individually, and large
commun-
ities have been established. Most of the development of 3D-
printed prostheses began after the establishment of the global
community e-NABLE. This community has grown into a
worldwide
movement of tinkerers, engineers, 3D-printing enthusiasts,
occu-
pational therapists, university professors, designers, parents,
fami-
lies, artists, students, teachers and people who have developed
3D-printed prostheses.[8] It all started with the idea of
developing
a cheap hand prosthesis.[9] The cost of a commercial body-pow-
ered prosthetic hand can range from $4000 to $10,000,[10] and
the cost of an externally powered prosthetic hand can range
from
$25,000 to $75,000.[10,11] The beginning of the development
of a
3D-printed hand prosthesis for people who cannot afford an
expensive commercial prosthesis resulted in the Robohand, as
shown in Figure 1.
3D-printing is an additive manufacturing technique. Products
are built up layer by layer instead of removing material from a
large piece of material, such as in CNC milling. 3D-printing has
several advantages compared with other manufacturing techni-
ques [12,13]:
� It is possible to make products out of one part; therefore,
no assembly is required.
� There is large design freedom; therefore, highly complex
geometries can be made.
� Designs can easily be personalized and customized; there
is no need to change the machine.
� Parts can be produced cheaply and quickly from idea to
end product, which gives the advantage of rapid design
improvements.
3D-printing also has disadvantages compared to other manu-
facturing techniques [14,15]:
� It is hard to predict the mechanical properties. The result-
ing strength of a part is highly dependent on the
CONTACT Gerwin Smit [email protected] Department of
Biomechanical Engineering, Delft University of Technology,
Mekelweg 2, Delft 2628 CD, The
Netherlands
� 2016 The Author(s). Published by Informa UK Limited,
trading as Taylor & Francis Group
This is an Open Access article distributed under the terms of the
Creative Commons Attribution-NonCommercial-NoDerivatives
License (http://creativecommons.org/licenses/by-nc-nd/4.0/),
which permits non-commercial re-use, distribution, and
reproduction in any medium, provided the original work is
properly cited, and is not altered, transformed, or built upon in
any way.
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TECHNOLOGY, 2017
VOL. 12, NO. 3, 300–314
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fabrication method, and various parameters can be
selected depending on the printing orientation.
� The accuracy is highly affected by material shrinkage, dif-
ferent machine parameters and errors induced by the
CAD/CAM software as well as post processing.
� The size of an object is limited by the size of the printer.
Very large objects cannot be made with current 3D-print-
ing technology.
� 3D-printers can work with a limited amount of materials
compared with conventional manufacturing, which can
work with nearly any material.
Problem
Although many upper limb prostheses are being 3D-printed all
over the world, to the authors’ knowledge, there are no specific
design guidelines and there is no overview of all of the various
devices that have been designed and 3D-printed so far. Some
sci-
entific research is ongoing in the field of 3D-printing upper
limb
prostheses, but currently, most of the 3D-printing of these
devices
is performed by trial and error.
Goal
Our goal is to provide an overview with quantitative
information
about existing 3D-printed upper limb prostheses. We will
identify
the benefits and drawbacks of 3D-printed devices to enable
improvements of current devices based on the demands of pros-
theses users.
Methods
Currently, little information on 3D-printed hand prostheses is
available in the peer-reviewed literature. Therefore, information
from Internet databases and websites focused on 3D-printing
were included. The review consists of two parts: first, the
Scopus
and Web of Science databases were used; second, an Internet
search was performed on three websites:
� www.enablingthefuture.org
� www.3dprint.com
� www.3ders.org
Three websites were used. The first website contains a large
database of 3D-printed hand prostheses that have been devel-
oped for the worldwide community e-NABLE. The second and
third websites provide the most up to date information in the
field of 3D-printing. Only unique devices identified through the
literature and through website searches were included. Devices
based on similar designs were excluded. Only results in
the English language were used in this literature review. The
database and Internet searches were carried out using the fol-
lowing keywords: 3D-printing, rapid prototyping, hand, upper
limb, prosthetic, prosthetics and prostheses. Quantitative infor-
mation on the mechanical and kinematic specifications and
3D-printing technology used were extracted from the papers
and websites.
Exclusion and inclusion criteria
Partial finger prostheses and custom prostheses made for han-
dling a specific tool were excluded in the overview. Articles
related to the topic that were not found with the search criteria
but found from references in other papers were included.
Results
The review resulted in an overview with seven devices found
in the scientific literature and 51 devices found on the Internet.
The results are presented in three tables. The first table con-
tains general specifications and the mechanical characteristics
of
the hands. The second table provides information about the
kinematics of the hands. The third table provides information
from the field of 3D-printing technology that regarding the
hands. Each table is divided into two parts. The first part shows
the 3D-printed upper limb prostheses found in the scientific lit-
erature. The second part of the table shows the devices found
from the Internet search. Several specifications or
characteristics
from the prostheses are unknown and are identified with an
“–”symbol in the tables.
Mechanical specifications
Type of prosthesis and type of actuation
The general specifications of the prostheses and mechanical
speci-
fications of the fingers are shown in Table 1. Some examples of
the 3D-printed upper limb prostheses are shown in Figure 2.
Table 1 shows the type of prosthesis. These can be specified as
three different levels of prostheses:
� Hand (18): The amputation level is a partial hand.
� Forearm (37): The amputation level is below the elbow.
� Upper arm (3): The amputation level is above the elbow.
The various types of actuation for the various types of pros-
theses are shown in Figure 3. All prostheses for people with
partial hand loss are body powered. There are four actuation
methods for forearm prostheses: two are passive static, one is
passive adjustable, 14 are body powered and 20 are externally
powered. For externally powered prostheses, 19 are electrically
powered and one is powered by pressurized air. All the upper
arm prostheses are externally powered and all are electrically
powered.
Figure 1. Robohand: the hand that was the inspiration for the
development of
the global community. Image reproduced with permission from
Brod Marsh on
behalf of Robohand Australia see http://www.robohand.net/wp-
content/uploads/
2013/03/2013-03-29-11-10-58-b.jpg, i.e., the copyright holder.
3D-PRINTED UPPER LIMB PROSTHESES: A REVIEW 301
http://www.enablingthefuture.org
http://www.3dprint.com
http://www.3ders.org
http://www.robohand.net/wp-content/uploads/2013/03/2013-03-
29-11-10-58-b.jpg
http://www.robohand.net/wp-content/uploads/2013/03/2013-03-
29-11-10-58-b.jpg
Type of actuation and type of control
The different types of actuation for the different types of
control
are shown in Figure 4. The two passive static prostheses [37,50]
are a decorative prosthesis, as opposed to the other prostheses,
which are more practical and more functional prostheses. One of
the prosthesis is passive adjustable.[57] This prosthesis has four
rigid fingers and an adjustable thumb that is made by modifying
an existing prosthetic hook. The 32 body-powered prostheses
can
be divided into prostheses controlled by flexing the thumb (1),
flexing the wrist (17), flexing the elbow (4) and through the use
of a shoulder harness (4), and for six prostheses, the actuation
method was not mentioned. It is unknown how these devices are
actuated. Presumably, they can be used with a shoulder harness
because they all make use of one output cable that controls all
the fingers. There were 23 prostheses found that are externally
powered from, two of which are controlled by
electroencephalog-
raphy (EEG), 20 of which are controlled by electromyography
(EMG) and one of which is voice controlled.[24]
Table 1. General specifications and mechanical specifications of
the 3D-printed hand prostheses.
Type of Prosthesis Type of Actuation Type of Control Weight
(g) Force distribution Flexor Extensor
Prostheses found in the scientific literature
Andrianesis’ hand [1], Figure 2(a) Forearm EP EMG 350
Independent Cables/cords ML
Bahari’s hand [2] Forearm EP EMG – Independent ML
Cables/cords
Gosselin’s hand [3], Figure 2(b) Forearm BP SH – Distributed
Cables/cords Cables/cords
Gretsch’ HAND [4] Forearm EP EMG 240 Independent
Cables/cords Elastic cords
Groenewegen’s hand [5] Forearm BP – 71 Distributed ML CM
O’Neill’s HAND [6] Forearm EX EMG 960 Independent
Cables/cords Cables/cords
Simone’s hand [7] Forearm EP EMG – Independent
Cables/cords Cables/cords
Prostheses found by performing an internet search
3D-printed prosthesis ecuador [16] Forearm EP EMG –
Independent Cables/cords Cables/cords
Adjustable thumb [17] Hand BP Wrist – Equal Cables/cords
Elastic cords
Biohand [18] Forearm EP EMG – Independent ML ML
Bionico hand [19] Forearm EP EMG – Independent
Cables/cords Cables/cords
Cyborg arm [20] Forearm BP Elbow – Equal Cables/cords
Elastic cords
Cyborg beast [21], Figure 2(c) Hand BP Wrist 1.315 Equal
Cables/cords Elastic cords
Cyborg beast with I.W.M. [22] Hand BP Wrist – Equal
Cables/cords Elastic cords
Dextrus EMG [23] Forearm EP EMG 450 Independent
Cables/cords Cables/cords
DIY prosthetic hand & forearm [24] Forearm EP Voice –
Independent Cables/cords Cables/cords
Falcon hand V1 [25] Hand BP Wrist – Equal Cables/cords
Elastic bands
Falcon hand V2 [26] Hand BP Wrist – Equal Cables/cords
Elastic bands
Flexy arm [27] Forearm BP Elbow – Equal Cables/cords CM
Flexy hand [28] Forearm BP – – Equal Cables/cords CM
Flexy hand 2 [29] Hand BP Wrist – Equal Cables/cords CM
Flexy hand – filaflex remix [30] Forearm BP – – Equal
Cables/cords CM
Galileo hand [31] Forearm BP SH – Equal Cables/cords Elastic
cords
HACKberry [32] Forearm EP EMG – Independent ML ML
Handiii [33] Forearm EP EMG – Independent ML ML
Handiii COYOTE [34] Figure 2(d) Forearm EP EMG 750
Independent ML ML
Hollies hand [35] Hand BP Wrist – Equal Cables/cords CM
InMoov 2 hand [36] Forearm EP EMG 450 Independent ML ML
IVIANA 2.0 [37] Figure 2(e) Forearm PS N/A – N/A N/A N/A
JD-1 [38] Forearm BP – – Distributed Cables/cords CM
K-1 [39] Hand BP Wrist – Equal Cables/cords Elastic cords
Latest bionic arm [40] Forearm EP EMG 250 Independent
Cables/cords CM
Limbitless Arm [41] Upper arm EP EMG – Equal Cables/cords
CM
Manu print (Re hand) [42] Forearm BP – – Distributed
Cables/cords Elastic cords
Mind controlled robotic hand [43] Upper arm EP EEG –
Independent Cables/cords Cables/cords
Muscle robot hand [44] Forearm EP EMG – Independent
Compressed air CM
Not impossible [45] Forearm BP Elbow – Equal Cables/cords
Elastic cords
Nu hand [46] Forearm EP EMG – Independent Cables/cords
Elastic cords
Odysseus hand [47] Hand BP Wrist – – Cables/cords Elastic
cords
One-hinged Cyborg beast [48] Hand BP Wrist – Equal
Cables/cords Elastic cords
Prosthetic/robotic hand [49] Forearm BP – – Equal Cables/cords
Elastic bands
Pr�otesis Cosm�etica [50] Forearm PS N/A – N/A N/A N/A
Raptor hand [51] Hand BP Wrist – Equal Cables/cords Elastic
cords
Raptor reloaded [52] Hand BP Wrist – Equal Cables/cords
Elastic cords
RIT arm [53] Forearm BP Elbow – Equal Cables/cords Elastic
cords
Roboarm [54] Upper arm EP EEG 2000 Independent
Cables/cords Cables/cords
Robohand [55] Hand BP Wrist – Equal Cables/cords Elastic
cords
Robot hand [56] Forearm EP EMG – Equal Cables/cords CM
Scand [57] Figure 2(f) Forearm PA N/A – N/A N/A N/A
Snap-together Robohand [58] Hand BP Wrist – Equal
Cables/cords Elastic cords
Tact [59] Forearm EP EMG 350 Independent Cables/cords
Elastic bands
Talon flextensor 1.0 [60] Hand BP Wrist – Equal Cables/cords
Elastic cords
Talon hand 2.0 [61] Hand BP Wrist – Equal Cables/cords
Elastic cords
Tenim hand [62] Forearm BP SH – Distributed Cables/cords
Cables/cords
The lucky paw prosthetic hand [63] Hand BP Finger – Equal
Cables/cords Elastic cords
Victory hand [64] Forearm BP SH – Distributed ML ML
Youbionic [65] Forearm EP EMG – Independent ML ML
Zero point frontiers [66] Hand BP Wrist – Equal Cables/cords
Elastic cords
BP: body-powered; EP: externally powered; PS: passive static;
PA: passive adjustable; SH: shoulder harness; ML: mechanical
linkages; CM: compliant mechanisms.
302 J. T. KATE ET AL.
Weight
The weight of only 11 of the 58 printed upper limb prostheses
is specified, as shown in Table 2. The lightest device was devel-
oped by M. Groenewegen [5] and weighs 71 g. The heaviest
device is the Roboarm developed by Unlimited Tomorrow,[54]
with a weight of 2000 g. The remainder of the hands have a
weight ranging from 132 g [21] to 960 g,[6] with most of them
(6) ranging from 240 g [4] to 450 g.[23,36] The weight of some
of the devices given in the table is not the total weight of the
prosthesis:
� Although the Cyborg Beast has the second lowest weight
(131.5 g) compared with the others, this weight is of a
prosthesis for a 3-year child. To print this hand for a 16-
year-old child, it should be scaled by 140%, which would
result in a weight of 184.2 g.[67]
� The Roboarm is a lot heavier than the other prostheses
because it is a complete arm. The developers state that it
is made from 2 kg of plastic. Therefore, the total weight
Figure 2. Examples of 3D-printed upper limb prostheses (a)
Andrianesis’ Hand: an externally powered forearm prosthesis.
Andrianesis and Tzes [1], with permission of
Springer. (b) Gosselin’s hand: a body powered forearm
prosthesis. Original source: Laliberte et al. No changes made.
Reproduced under creative commons attribution
3.0 [3]. (c) Cyborg beast: a body-powered hand prosthesis.
Published with permission of Zuniga [21]. (d) Handiii
COYOTE: an externally powered forearm prosthesis.
#exiii, Inc. published with permission [34]. (e) IVIANA 2.0: a
passive forearm prosthesis. Published with permission of Evan
Kuester [37]. (f) Scand: a passive adjustable
forearm prosthesis. Original source
http://www.instructables.com/id/3D-Printing-Prosthetic-Hand-
Make-it-Real-Challen/Scott Allen. No changes made.
Reproduced under
creative commons attribution 3.0 [57].
Figure 3. Almost two-thirds of the devices are forearm
prostheses from which
slightly more than half of the devices are externally powered.
3D-PRINTED UPPER LIMB PROSTHESES: A REVIEW 303
http://www.instructables.com/id/3D-Printing-Prosthetic-Hand-
Make-it-Real-Challen/Scott
will be even greater due to the weight of the motors and
electronic parts.
� The advanced, low-cost prosthetic arm developed by
C. O’Neill weighs 960 g. This includes a socket, but
excludes the haptic feedback sensors.[6]
� The weight of the prosthesis developed by Andrianesis
et al. [1] is 350 g, including a cosmetic glove, but exclud-
ing the 180-g battery.
Force distribution
The various types of force distribution between the fingers of
each hand are shown in Figure 5. The total number of prostheses
shown in this figure is 55. The three passive prostheses are
excluded. The specifications related to force distribution
between
the fingers are specified for only a small portion of the hands.
For
the hands in which the force distribution was not specified, we
determined the specifications based on videos and images. The
force distribution between the fingers is equal for the majority
of
hands (28): when the hand is actuated, the force is equally
distrib-
uted over the fingers. The minority of the prostheses (6) have
fin-
gers with force distribution over the fingers, which ensures an
adaptive grasp. In these prostheses, the other fingers can still
apply a force when some of the fingers are halted by an object.
The remainder of the prostheses (21) have fingers with
independ-
ent force, with one motor per finger. This also enables an adap-
tive grasp and enables a large variety grasp types.
Type of flexor
The different types of flexors used to close the hand are shown
in
Figure 6. All the body-powered prostheses found to make use of
the voluntary closing principal. Voluntary closing devices close
when they are actuated and return to their natural open position
when the force is released. The majority of devices (45) use
cables
or non-elastic cords to close the hand. When flexing the wrist or
elbow, the cables or cords attached to the end of the fingers
ensure that they make a closing grasp. The remainder of the
devi-
ces makes use of a mechanical solution without cables or cords.
Figure 4. Slightly more than half of all the prostheses are body
powered from which slightly more than half of the devices are
controlled by the wrist.
Figure 5. More than half of the actuated hands have an equal
force between
the fingers. Slightly more than a third of the hands have fingers
with independ-
ent force due to a separate motor for each finger. Only a small
number of the
hands have a mechanical linkage system to distribute the force
along the fingers.
Table 2. Weight of the 3D-printed hand prostheses. Only
11 of the 58 3D-printed upper limb prostheses specified
their weights.
Weight (g)
Andrianesis’ hand [1] 350
Gretsch’ hand [4] 240a
Groenewegen’s hand [5] 71b
O’Neill’s hand [6] 960
Cyborg beast [21] 131.5
Dextrus EMG [23] 450
Handiii COYOTE [34] 750
InMoov 2 hand [36] 450b
Latest bionic arm [40] 250
Roboarm [54] 2000
Tact [59] 350b
aEstimated weight by the developers.
bExcluding connector or socket to fit a human arm.
304 J. T. KATE ET AL.
Nine hands use mechanical linkages controlled by motors, and
one hand uses compressed air to close the fingers.[44]
Type of extensor
Figure 7 shows the different solutions that are used to open the
hand. A large number (36) of prostheses use elasticity to open
the
hand automatically. This is achieved through the use of elastic
cords (21) and elastic bands (4), and a large number of devices
use the elasticity of the finger joints (11) to open the hand. The
elastic finger joints are called compliant mechanisms. Hands
with
these compliant mechanisms consist of fingers that are made
from one piece where the phalanges are rigid and the joints are
flexible. The remainder of the prostheses have cables or cords
(11)
or mechanical linkages (8), which are, in both, cases attached to
motors.
Kinematic specifications
The kinematic specifications of each prosthesis are shown in
Table 3. The table shows how many joints and degrees of free-
dom (DOF) a hand has, how many actuators it has, the range of
motion of the different joints and the different grasp types a
hand can perform. Most of the information in these tables has
been estimated based on published images and videos, as it was
not mentioned in the publications. For some hands, basic
informa-
tion related to the number of actuators or the DOF was
specified.
Only Andrianesis [1] and Bahari [2] described their hand in
more
detail and specified the numbers; the remaining hands lack
infor-
mation related to the kinematic specifications, e.g., DOF�s,
ROM
and possible grasp type.
Number of joints, DOF and actuators
All the active hands are underactuated, which means that they
have more DOF’s than actuators. This is due to the coupling
of the phalanges in the fingers. Most of the fingers of the body-
powered prostheses consist of three phalanges that are
connected
to each other with cables, cords and so on. The cables from all
the separate fingers are then attached to one linkage, which
ensures that the fingers all move at the same time. For
externally
powered prostheses, the phalanges are connected to each other
with cables or mechanical linkages and are directly connected to
motors. The motors control the fingers separately.
Range of motion
Each finger of a human hand has four joints. The
carpometacarpal
(CMC) joint, the metacarpo phalangeal (MCP) joint, the
proximal
interphalangeal (PIP) joint and the distal interphalangeal (DIP)
joint.[68] The thumb of a human hand only has three joints. It
has
no DIP joint, and instead of a PIP joint, it has an
interphalangeal
(IP) joint, which is described in the table as thumb flexion. The
CMC joint of the thumb is also known as the trapeziometacarpal
(TMC) joint. This joint is described in the table as thumb
circum-
duction. None of the 3D-printed hands found have a CMC joint.
Except for passive hands, all the hands have an MCP joint and a
PIP joint. Only 31 of the 56 active hands have an active DIP
joint.
Grasp type
An adaptive grip is the ability of the fingers to conform to the
shape of an object held within the hand. In this case, the force
is
distributed between the fingers, which ensures that some fingers
can still apply a force when the others fingers are halted by an
object. This can be performed by 24 of the prostheses, of which
18 can do this by controlling the fingers separately by
controlling
the motors independently. The hand that is actuated with air
pressure can perform an adaptive grip by controlling the
pressure
in the separate fingers with the use of valves. Only five
prostheses
have a smart mechanism that distributes the force over all of the
fingers.
The power grip and precision grip are the two basic grasps a
human uses.[69] In addition to these basic grasps, there are four
other common types of grasps that are used to perform activities
of daily living (ADLs). These four types are the hook grip,
spherical
grip, tripod grip and lateral grip.[70] All the active hands (56)
can
perform a power grip, and the majority (54) can also perform a
lateral grip. The precision grip can only be performed by 24 of
the hands. Almost one-quarter (14) of the hands can perform all
six grasp types, which are, in most cases, electrically powered
hands with an adaptive grip.
3D-printing technology used to print the upper limb prostheses
3D-printing technique
The information related to the 3D-printing technology used to
print the prostheses is shown in Table 4. The various techni-
ques that are used to print the prostheses are shown in
Figure 8. Most of the devices (46) are printed using fused
deposition modelling (FDM) technology. The remaining
prosthe-
ses are made using selective laser sintering (SLS) technology
(6), selective stereolithography apparatus (SLA) technology (1),
and polyjet printing (1), but in the case of four prostheses, the
printing technique is unknown. FDM is the only technique that
uses a continues filament to print the part. The other techni-
ques make use of a powder or liquid bonded together with
the use of a UV laser or UV light.
3D-printing material
There is a large variety of materials that can be used for 3D-
print-
ing. Acrylonitrile butadiene styrene (ABS) and polylactic acid
(PLA)
are the most commonly used materials to print the prostheses.
Figure 6. The type of flexor used to close the prosthesis. The
majority of the
hands use cables or cords to close the hand. The remainder of
the hands use
mechanical linkages and one uses compressed air.
Figure 7. The type of extensor used to open the prosthesis.
Almost two-thirds of
the hands use elasticity in the form of elastic cords or bands or
compliant mech-
anisms to open the hand automatically.
3D-PRINTED UPPER LIMB PROSTHESES: A REVIEW 305
Ta
b
le
3.
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[1
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h
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sp
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ic
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[4
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15
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(B
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0–
45
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N
/A
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s,
M
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w
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la
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l
G
re
ts
ch
’
h
an
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[5
]
10
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/A
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90
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/A
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s,
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.
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w
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h
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la
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[6
]
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45
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s,
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m
on
e’
s
h
an
d
[7
]
15
15
5
0–
11
0
0–
90
0–
90
0–
45
N
/A
Ye
s,
El
.
Po
w
er
,
p
re
ci
si
on
Pr
os
th
es
es
fo
un
d
w
it
h
th
e
in
te
rn
et
se
ar
ch
3D
-p
ri
n
te
d
p
ro
st
h
es
is
ec
ua
d
or
[1
6]
15
15
5
0–
90
0–
90
0–
90
0–
90
0–
90
Ye
s,
El
.
Po
w
er
,
p
re
ci
si
on
,
la
te
ra
lþ
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,T
,S
A
d
ju
st
ab
le
th
um
b
[1
7]
11
11
1
(B
P)
0–
45
0–
60
N
/A
0–
60
N
/A
N
o
Po
w
er
,
p
re
ci
si
on
,
la
te
ra
l
Bi
oh
an
d
[1
8]
10
10
5
0–
90
0–
90
N
/A
N
/A
0–
45
Ye
s,
El
.
Po
w
er
,
p
re
ci
si
on
,
la
te
ra
l
Bi
on
ic
o
h
an
d
[1
9]
16
16
5
0–
75
0–
90
0–
80
0–
90
0–
45
Ye
s,
El
.
Po
w
er
,
p
re
ci
si
on
,
la
te
ra
lþ
H
,T
,S
C
yb
or
g
ar
m
[2
0]
10
10
1
(B
P)
0–
45
0–
60
N
/A
0–
60
N
/A
N
o
Po
w
er
,
la
te
ra
l
C
yb
or
g
b
ea
st
[2
1]
,
Fi
g
ur
e
2(
c)
10
10
1
(B
P)
0–
45
0–
60
N
/A
0–
60
N
/A
N
o
Po
w
er
,
la
te
ra
l
C
yb
or
g
b
ea
st
w
it
h
I.W
.M
.
[2
2]
10
10
1
(B
P)
0–
45
0–
60
N
/A
0–
60
N
/A
N
o
Po
w
er
,
la
te
ra
l
D
ex
tr
us
EM
G
[2
3]
15
15
5
0–
90
0–
90
0–
90
0–
90
0–
90
Ye
s,
El
.
Po
w
er
,
p
re
ci
si
on
,
la
te
ra
lþ
H
,T
,S
D
IY
p
ro
st
h
et
ic
h
an
d
&
fo
re
ar
m
[2
4]
16
16
5
0–
75
0–
90
0–
80
0–
90
0–
45
Ye
s,
El
.
Po
w
er
,
p
re
ci
si
on
,
la
te
ra
lþ
H
,T
,S
Fa
lc
on
h
an
d
V
1
[2
5]
13
13
1
(B
P)
0–
90
0–
90
0–
45
0–
90
N
/A
N
o
Po
w
er
,
la
te
ra
l
Fa
lc
on
h
an
d
V
2
[2
6]
11
11
1
(B
P)
0–
90
0–
90
N
/A
0–
90
0–
90
N
o
Po
w
er
,
Pr
ec
is
io
n
,
la
te
ra
l
Fl
ex
y
ar
m
[2
7]
14
14
1
(B
P)
0–
45
0–
80
0–
45
0–
30
N
/A
N
o
Po
w
er
,
la
te
ra
l
Fl
ex
y
h
an
d
[2
8]
14
14
1
(B
P)
0–
45
0–
80
0–
45
0–
30
N
/A
N
o
Po
w
er
,
p
re
ci
si
on
,
h
oo
k,
la
te
ra
l
Fl
ex
y
h
an
d
2
[2
9]
14
14
1
(B
P)
0–
45
0–
80
0–
45
0–
30
N
/A
N
o
Po
w
er
,
la
te
ra
l
Fl
ex
y
h
an
d
–
Fi
la
fle
x
re
m
ix
[3
0]
15
14
1
(B
P)
0–
90
0–
90
0–
45
0–
30
N
/A
N
o
Po
w
er
,
la
te
ra
l
G
al
ile
oH
an
d
[3
1]
11
11
1
(B
P)
0–
90
0–
90
N
/A
0–
90
0–
90
N
o
Po
w
er
,
p
re
ci
si
on
,
la
te
ra
l
H
A
C
Kb
er
ry
[3
2]
10
10
6
0–
90
0–
90
N
/A
N
/A
0–
90
Ye
s,
El
.
Po
w
er
,
p
re
ci
si
on
,
la
te
ra
l
H
an
d
iii
[3
3]
15
15
6
0–
90
0–
90
0–
90
0–
90
0–
90
Ye
s,
El
.
Po
w
er
,
p
re
ci
si
on
,
la
te
ra
lþ
H
,T
,S
H
an
d
iii
C
O
YO
TE
[3
4]
,
Fi
g
ur
e
2d
15
15
6
0–
90
0–
90
0–
90
0–
90
0–
90
Ye
s,
El
.
Po
w
er
,
p
re
ci
si
on
,
la
te
ra
lþ
H
,T
,S
H
ol
lie
s
h
an
d
[3
5]
10
10
1
(B
P)
0–
45
0–
20
N
/A
0–
20
N
/A
N
o
Po
w
er
,
la
te
ra
l
In
M
oo
v
2
h
an
d
[3
6]
15
15
4
0–
90
0–
90
0–
90
0–
90
0–
45
Ye
s,
El
.
Po
w
er
,
p
re
ci
si
on
,
la
te
ra
l
IV
IA
N
A
2.
0
[3
7]
,
Fi
g
ur
e
2(
e)
N
/A
N
/A
N
/A
N
/A
N
/A
N
/A
N
/A
N
/A
N
/A
N
/A
JD
-1
[3
8]
14
14
1
(B
P)
0–
45
0–
45
0–
45
0–
45
N
/A
N
o
Po
w
er
,
la
te
ra
l
K-
1
[3
9]
14
14
1
(B
P)
0–
90
0–
90
0–
45
0–
90
N
/A
N
o
Po
w
er
,
la
te
ra
l
La
te
st
b
io
n
ic
ar
m
[4
0]
15
15
5
0–
90
0–
45
0–
20
0–
90
0–
60
Ye
s,
El
.
Po
w
er
,
p
re
ci
si
on
,
la
te
ra
lþ
H
,T
,S
Pr
os
th
es
es
fo
un
d
w
it
h
th
e
in
te
rn
et
se
ar
ch
Li
m
b
it
le
ss
ar
m
[4
1]
14
14
1
(B
P)
0–
45
0–
80
0–
45
0–
30
N
/A
N
o
Po
w
er
,
p
re
ci
si
on
,
h
oo
k,
la
te
ra
l
M
an
u
p
ri
n
t
(R
e
h
an
d
)
[4
2]
14
14
1
(B
P)
0–
90
0–
90
0–
45
0–
45
N
/A
Ye
s,
M
e.
Po
w
er
,
la
te
ra
l
M
in
d
co
n
tr
ol
le
d
ro
b
ot
ic
h
an
d
[4
3]
16
16
5
0–
75
0–
90
0–
80
0–
90
0–
45
Ye
s,
El
.
Po
w
er
,
p
re
ci
si
on
,
la
te
ra
lþ
H
,T
,S
M
us
cl
e
ro
b
ot
h
an
d
[4
4]
5
>
5
1(
A
ir
)
0–
90
0–
90
0–
90
0–
90
N
/A
Ye
s,
Pn
eu
m
at
ic
Po
w
er
,
la
te
ra
l
N
ot
im
p
os
si
b
le
[4
5]
10
10
1
(B
P)
0–
90
0–
90
N
/A
0–
60
N
/A
N
o
Po
w
er
,
la
te
ra
l
N
u
h
an
d
[4
6]
19
19
1
(B
P)
0–
90
0–
90
0–
90
0–
90
0–
30
N
o
Po
w
er
,
p
re
ci
si
on
,
la
te
ra
lþ
H
,T
,S
O
d
ys
se
us
h
an
d
[4
7]
6
6
1
(B
P)
0–
90
0–
45
N
/A
0–
45
N
/A
N
o
Po
w
er
,
la
te
ra
l
O
n
e-
h
in
g
ed
C
yb
or
g
b
ea
st
[4
8]
8
8
1
(B
P)
0–
45
0–
60
N
/A
N
o
th
um
b
N
o
th
um
b
N
o
Po
w
er
Pr
os
th
et
ic
/r
ob
ot
ic
h
an
d
[4
9]
15
15
1
(B
P)
0–
90
0–
90
0–
90
0–
90
N
/A
N
o
Po
w
er
,
la
te
ra
l
Pr
� ot
es
is
C
os
m
� et
ic
a
[5
0]
N
/A
N
/A
N
/A
N
/A
N
/A
N
/A
N
/A
N
/A
N
/A
N
/A
Ra
p
to
r
h
an
d
[5
1]
10
10
1
(B
P)
0–
80
0–
90
N
/A
0–
70
N
/A
N
o
Po
w
er
,
la
te
ra
l
Ra
p
to
r
re
lo
ad
ed
[5
2]
10
10
1
(B
P)
0–
80
0–
90
N
/A
0–
90
N
/A
N
o
Po
w
er
,
la
te
ra
l
RI
T
ar
m
[5
3]
14
14
1
(B
P)
0–
90
0–
45
N
/A
0–
30
N
/A
N
o
Po
w
er
,
la
te
ra
l
Ro
b
oa
rm
[5
4]
14
14
5
0–
90
0–
90
0–
90
0–
90
N
/A
Ye
s,
El
.
Po
w
er
,
p
re
ci
si
on
,
la
te
ra
lþ
H
,T
,S
Ro
b
oh
an
d
[5
5]
10
10
1
(B
P)
0–
90
0–
90
N
/A
0–
90
N
/A
N
o
Po
w
er
,
la
te
ra
l
Ro
b
ot
h
an
d
[5
6]
15
15
1
(B
P)
0–
90
0–
90
0–
90
0–
90
N
/A
N
o
Po
w
er
,
sp
h
er
ic
al
Sc
an
d
[5
7]
,
Fi
g
ur
e
2(
f)
1
1
1(
BP
)
N
/A
N
/A
N
/A
0–
90
N
/A
N
o
Po
w
er
,
la
te
ra
l
Sn
ap
-t
og
et
h
er
Ro
b
oh
an
d
[5
8]
10
10
1
(B
P)
0–
90
0–
90
N
/A
0–
90
N
/A
N
o
Po
w
er
,
la
te
ra
l
(c
on
ti
nu
ed
)
306 J. T. KATE ET AL.
These are the most common materials used for printing with
FDM, which is the most commonly used technique to print the
devices. The prostheses that are made from flexible materials
and
FDM 3D-printing make use of NinjaFlex or Filaflex. The
chemical
name for NinjaFlex is thermoplastic polyurethane.[71] Filaflex
is a
thermoplastic elastomer with a polyurethane base and some
addi-
tives.[72] Both these materials stay flexible after first being
heated
and then cooled down. The prostheses made using SLS 3D-
print-
ing are made from nylon. SLS 3D-printing most commonly uses
standard nylon 11 or nylon 12. The prosthesis made using SLA
3D-printing is made of acrylic plastic, and the prosthesis made
using polyjet 3D-printing is made from FullCure 720, which is a
photopolymer resin. The Tenim Hand is the only prosthesis that
consists of a non-plastic material. This device is made in
multiple
steps; first, a part from polystyrene is 3D-printed and is then
cov-
ered with a ceramic layer. The polystyrene is then melted away
leaving a cavity in the ceramic that is filled with nylon. This
pro-
duction method is known as the lost wax casting. Therefore, this
prosthesis was made using 3D-printing only as a step in the pro-
duction process.
Production cost
The cost of 20 prostheses is specified and ranges from $5 to
$500. The prosthesis that is specified with the lowest cost of $5
only states the cost of the material that is used for the 3D-print-
ing. The prosthesis that has the greatest specified cost of $500
states the cost of all the materials that are needed to
manufacture
the entire hand (e.g., cables, motors, electronics). There are no
prostheses that can be bought off-the-shelf; however, there are
some companies working on prostheses that could be sold for
$1000; for example, You Bionic and Open Bionics are
developing
a prosthesis that they would like to sell for $3000.
Design availability
The designs of 31 of the 58 different printed prostheses are
avail-
able online. Most of the designs can be found on www.thingi-
verse.com or www.instructables.com. People can download the
CAD-model, print the model and, if necessary, modify the
model.
Discussion
A prosthesis should meet the basic user demands to increase the
usability of the prosthesis; these demands can be summarized as
cosmesis, comfort, control and function.[73] A prosthesis
should
be beautiful to look at, comfortable to wear, easy to operate and
should have a functional use. A limitation of this study was that
a
great deal of information on the state of the art 3D-printed
upper
limb prostheses was found on public websites that are not peer-
reviewed. However, we believe, in general, the obtained values
appear to be in line with values from the literature.
Cosmesis of hand prostheses
After functional factors, the appearance is one of the most
import-
ant factors in prosthesis rejection.[74] To ensure that a
prosthesis
has an appealing look, the term anthropomorphic is used in the
field of prosthetics. This term refers to the capability of a
device to
mimic the general aspects of the human hand, such as shape,
size,
colour, temperature and aesthetic factors.[75] All the 3D-
printed
prostheses are designed to resemble the shape of a human hand,
except some hands have a thumb that is positioned at 90� or
even
at 155� with respect to the fingers. The average size of a
human
hand has a length of 180–198 mm and a width of 75–90
mm.[76]Ta
b
le
3.
C
on
ti
n
ue
d
Ra
n
g
e
of
m
ot
io
n
G
ra
sp
ty
p
e
Jo
in
ts
D
O
F
A
ct
ua
to
rs
M
C
P
jo
in
ts
(�
)
PI
P
jo
in
ts
(�
)
D
IP
jo
in
ts
(�
)
Th
um
b
fle
xi
on
(�
)
Th
um
b
ci
rc
um
d
uc
ti
on
(�
)
A
d
ap
ti
ve
g
ri
p
A
ch
ie
va
b
le
g
ra
sp
s
Ta
ct
[5
9]
11
11
6
0–
90
0–
90
N
/A
0–
90
0–
90
Ye
s,
El
.
Po
w
er
,
p
re
ci
si
on
,
la
te
ra
lþ
H
,T
,S
Ta
lo
n
fle
xt
en
so
r
1.
0
[6
0]
10
10
1
(B
P)
0–
10
0
0–
45
N
/A
0–
90
N
/A
N
o
Po
w
er
,
la
te
ra
l
Ta
lo
n
h
an
d
2.
0
[6
1]
10
10
1
(B
P)
0–
90
0–
90
N
/A
0–
90
N
/A
N
o
Po
w
er
,
la
te
ra
l
Te
n
im
h
an
d
[6
2]
15
15
1(
BP
)
0–
90
0–
90
0–
90
0–
90
0–
90
Ye
s,
M
e.
Po
w
er
,
p
re
ci
si
on
,
la
te
ra
lþ
H
,T
,S
Th
e
lu
ck
p
aw
p
ro
st
h
et
ic
h
an
d
[6
3]
12
12
1
(B
P)
0–
90
0–
90
0–
90
N
o
th
um
b
N
o
th
um
b
N
o
Po
w
er
V
ic
to
ry
h
an
d
[6
4]
14
14
1
(B
P)
0–
90
0–
45
0–
45
0–
45
0–
90
N
o
Po
w
er
,
p
re
ci
si
on
,
la
te
ra
l
Yo
ub
io
n
ic
[6
5]
11
11
5
0–
90
0–
90
N
/A
0–
45
0–
45
Ye
s,
El
.
Po
w
er
,
p
re
ci
si
on
,
la
te
ra
lþ
H
,T
,S
Ze
ro
p
oi
n
t
fr
on
ti
er
s
[6
6]
6
6
1
(B
P)
0–
90
0–
45
N
/A
N
o
th
um
b
N
o
th
um
b
N
o
Po
w
er
BP
:
b
od
y
p
ow
er
ed
;
M
e.
:
m
ec
h
an
ic
al
;
El
.:
el
ec
tr
ic
al
;
H
,T
,S
:
h
oo
k,
tr
ip
od
,
sp
h
er
ic
al
.
3D-PRINTED UPPER LIMB PROSTHESES: A REVIEW 307
http://www.thingiverse.com
http://www.thingiverse.com
http://www.instructables.com
Only the prosthesis developed by Andrianesis specifies the
exact
dimensions of the prosthesis. The length of this hand is 174 mm
and the width is 72 mm. This is slightly smaller than the size of
an
average human hand. The rest of the hands described in the
litera-
ture and found on internet do not mention the size. They only
mention that the size of the hand can be scaled to match the
sound limb. However, this is not possible for hands that are
con-
trolled by the wrist. These prostheses are fitted to the residual
limb, which results in a bigger hand than the sound hand.
The majority of the hands have a brightly coloured appearance.
Whereas adults appreciate more skin-coloured prostheses,[77]
chil-
dren may appreciate a coloured appearance.[78] The prostheses
developed for adults primarily have a skin colour appearance.
Most
of the existing conventional prostheses are covered with a cos-
metic glove that has a skin-coloured look. Currently, two types
of
cosmetic gloves are available: a polyvinylchloride (PVC) glove
and a
silicone glove.[79] The main function of a cosmetic glove is to
cover
the mechanism and provide the prosthesis with a natural appear-
ance. In addition to this main function, the glove also protects
the
mechanism against moisture and dirt. A negative effect of a
Table 4. Print specifications of the 3D-printed hand prostheses.
The first part of the table shows the 3D-printed upper limb
prostheses found
in scientific literature and the second part of the table shows the
devices found with the internet search.
Fabrication method Material Material cost ($) Design
availability
Prostheses found in scientific literature
Andrianesis’ hand [1], Figure 2(a) SLS Duraform HST – No
Bahari’s hand [2] SLA Acrylic plastic – No
Gosselin’s hand [3], Figure 2(b) FDM ABS – No
Gretsch’ hand [4] FDM ABS 300 No
Groenewegen’s hand [5] SLS Nylon – No
O’Neill’s hand [6] FDM ABS 500 No
Simone’s hand [7] Polyjet Full Cure 720 – No
Prostheses found with the internet search
3D-printed prosthesis ecuador [16] FDM – 270 No
Adjustable thumb [17] FDM ABS – No
Biohand [18] FDM – ±300 No
Bionico hand [19] FDM ABS 250 Yes
Cyborg arm [20] FDM ABS – No
Cyborg beast [21], Figure 2(c) FDM ABS 50 Yes
Cyborg beast with I.W.M. [22] FDM ABS – No
Dextrus EMG [23] FDM PLA or ABS ±1000 Yes
DIY prosthetic hand & forearm [24] FDM – – Yes
Falcon hand V1 [25] FDM ABS – Yes
Falcon hand V2 [26] FDM ABS – Yes
Flexy arm [27] FDM FLA & Filaflex – Yes
Flexy hand [28] FDM FLA & Filaflex – Yes
Flexy hand 2 [29] FDM FLA & Filaflex – Yes
Flexy hand – Filaflex remix [30] FDM Filaflex – Yes
GalileoHand [31] FDM PLA or ABS – Yes
HACKberry [32] FDM – 200 Yes
Handiii [33] Unknown – 300 No
Handiii COYOTE [34], Figure 2(d) Unknown – 300 No
Hollies hand [35] SLS Nylon – Yes
InMoov 2 hand [36] FDM – – Yes
IVIANA 2.0 [37], Figure 2(e) Unknown – – No
JD-1 [38] FDM Nylon – No
K-1 [39] FDM – – No
Latest bionic arm [40] FDM – ±3000 No
Limbitless arm [41] FDM ABS & Ninjaflex 350 Yes
Manu print (Re hand) [42] FDM – 20 No
Mind controlled robotic hand [43] FDM ABS 500 Yes
Muscle robot hand [44] FDM PLA & Silicone – Yes
Not impossible [45] FDM – 100 No
Nu hand [46] FDM – – No
Odysseus hand [47] FDM ABS – Yes
One-hinged Cyborg beast [48] FDM ABS – Yes
Prosthetic/robotic hand [49] FDM PLA 1 Yes
Pr�otesis Cosm�etica [50] Unknown – – No
Raptor hand [51] FDM PLA – Yes
Raptor reloaded [52] FDM PLA – Yes
RIT arm [53] FDM – – Yes
Roboarm [54] FDM PLA 350 Yes
Robohand [55] FDM ABS 500 Yes
Robot hand [56] FDM ABS & flexible plastic – Yes
Scand [57], Figure 2(f) SLS DM_9795 & DM_9770 – No
Snap-together Robohand [58] FDM PLA – Yes
Tact [59] FDM – 250 Yes
Talon flextensor 1.0 [60] FDM ABS – Yes
Talon hand 2.0 [61] FDM ABS – Yes
Tenim hand [62] SLS Nylon with ceramic layer – No
The lucky paw prosthetic hand [63] FDM – – Yes
Victory hand [64] FDM – 100 No
Youbionic [65] SLS Nylon ±1000 No
Zero point frontiers [66] FDM PLA 5 No
308 J. T. KATE ET AL.
cosmetic glove is that it results in a greater operational force
due
to the stiffness of the material. As an extra part for a prosthesis,
the
glove results in extra costs. None of the 3D-printed hands used
a
standard glove to cover the mechanism. They are not designed
in
such a way that a cosmetic glove can cover the mechanism.
Only
the hand developed by Andrianesis uses a custom fabricated
sili-
cone glove. As stated previously, the majority of the hands have
a
colour that does not look like human skin. These prostheses can
also be printed using a filament that has a skin colour to give
them
a skin-like appearance. The Flexy Hand 2 and the Flexy Hand-
Filaflex remix are both made using a skin-coloured filament.
Protecting the mechanism from moisture and dirt is one of the
advantages of a glove. The disadvantages of a glove are the
greater
operation force required and the additional cost.[79] Printing a
prosthesis with skin-coloured appearance results no greater
oper-
ational force needed and no extra cost required to cover the
mech-
anism to give the hand a natural appearance. More than one
third
of the hands are electrically powered in most cases with a servo
motor. This results in a noise that can be an undesired aspect of
electrically powered hands. Although all prostheses were
designed
in the shape of a human hand and the majority of the hands can
be scaled to the size of the sound hand, most of them still have
a
non-anthropomorphic look. The appearance of most of the hands
is not similar to the appearance of the sound hand. The majority
of
the hands look more like a mechanical hand than a cosmetic
hand,
which might result in a greater prosthesis rejection rate.
Comfort of hand prostheses
A comfortable prosthesis has a good fit and weight that satisfies
the user. Almost half of the hands are fitted to the residual limb
and tightened using Velcro. The remaining hands can be con-
nected to an existing socket. In the Internet and literature
search,
the prostheses were found to be easily fitted on the residual
limb
or connected to an existing socket. No information is published
on tests or research that has measured the comfort of these pros-
theses, and current evidence is mainly anecdotal. The human
hand has an average weight of 400 ± 90 g [80] (distal to the
wrist
and not including the forearm extrinsic muscles). Excessive
weight
is one of the most important causes of prostheses rejection.[81]
Therefore, it is important to provide the weight specifications of
the hand prostheses. For 11 devices, the weight of the hand and
part of the arm is specified. For four devices, the weight of only
the hand is specified:
� Groenewegen’s hand: 71 g
� Dextrus EMG: 450 g
� InMoov 2 hand: 450 g
� Tact: 350 g
Groenewegen’s hand is extremely light. All the parts for this
hand are printed using SLS 3D-printing and are optimized for
weight reduction. The other three hands have a comparable
weight as the human hand. Comparing the weight of the other
seven prostheses shows that six of the prostheses have a similar
weight or even a lower weight as similar human arm parts. Only
the Cyborg beast has a greater weight than the human body part
it replaces. The Cyborg beast is a partial hand prosthesis that
replaces the fingers but consists of fingers, a support
mechanism
and a support to be mounted onto the human hand. The weight
of the other partial hand prostheses will probably be greater
than
the human body part it replaces as well because they are
designed in the same way as the Cyborg beast. Although the
prostheses that specify a weight have a comparable or slightly
lower weight as the human body part it replaces, they are still
heavier than some of the commercial available body powered
prosthesis.[82] Additionally, it is preferred to have prosthesis
that
is considerably lighter than 400 ± 90 g.[83] This preferred
weight is
highly related to the length of the stump. For partial hand pros-
theses, the weights are greater than the human body part it
repla-
ces. To increase the comfort of 3D-printed upper lump
prosthesis,
it is important that specifications related to weight and fitting of
future prostheses are provided.
Hand prostheses control
Almost 64% of the hands (37) are developed for people with an
amputation level below elbow and 31% of the hands (18) are
developed for people with a partial hand amputation level. The
remaining hands (3) are developed for people with an
amputation
level above the elbow. This is remarkable as we compare it to
numbers for amputation levels in the USA.[84] The literature
shows that approximately 25% have an above elbow amputation
level, whereas only three 3D-printed hand prostheses have been
developed for this purpose. For partial hand amputation, the lit-
erature indicates that these procedures are less than 10%,
whereas 31% of the 3D-printed hand prostheses are developed
for a partial hand amputation level. The exact numbers for the
percentages of passive, body-powered and externally powered
prosthesis users are unknown.[81] In general, still a remarkable
number of people use a passive cosmetic prosthesis,[85]
whereas
only two of the 58 3D-printed hand prostheses are passive pros-
theses. With respect to the type of actuation for the 3D-printed
upper limb prostheses, three of the prostheses are passive, 32 of
the prostheses are body-powered and 23 are externally powered.
Therefore, the focus of 3D-printed upper limb prostheses is
more
on body-powered and externally powered than on passive pros-
theses. Almost 30% of the hands (17) have been developed for
people with partial hand loss. These prostheses are body
powered
and can only be controlled by the wrist. The prostheses devel-
oped for all other levels of amputation have a large variety in
their type of actuation and type of control.
Hand prostheses function
The total active range of motion of a human finger is 260�,
which
is the sum of active flexion at the MCP joint (85�), the PIP
joint
(110�) and the DIP joint (65�).[68] A little more than one-
third of
the hands (20) have this range of motion as well. The range of
motion of the thumb is very important when performing
precision
grasp. The thumb circumduction ensures this grasp. Less than
half
of the hands (20) enable active thumb circumduction. More than
a third of the hands (24) can perform adaptive grasp. Only five
of
the hands have a smart mechanism to enable adaptive grasp.
The remainder of the hands, which can perform an adaptive
grasp, does this by controlling each finger independently with a
Figure 8. The various fabrication methods used to print the
prostheses. The
majority of the devices are made using FDM technology
3D-PRINTED UPPER LIMB PROSTHESES: A REVIEW 309
separate motor. Using a smart mechanism instead of using mul-
tiple motors can lead to significant weight reduction.[86]
Although the power grip and precision grip are the most import-
ant types of grip in daily life, only 24 of the hands can perform
these two types of grip. However, almost all the hands can per-
form a power grip and a lateral grip. Future hands should focus
more on the most important grasp types used in daily live. This
can increase the amount of ADLs a person can perform.
The most important aspect of a hand is the ability to perform
a secure grip, which is a combination of a grasp type and an
applied force. It is only possible to predict the usability of a
hand
related to tasks if the forces of the hand are specified. Whereas
the forces are very important, the forces are only specified from
one hand. The Andrianesis’ hand can provide fingertip forces of
3.9–11.5 N and has a maximum grip load of 1.5 kg. The
fingertip
force of a human hand is 30 N.[87] Although the fingertip
forces
of the Andrianesis’ hand are relatively low compared with a
human hand, it is still sufficient for most ADLs.[68] There are
no
specifications provided, such as the actuation force, maximum
grip force or maximum load, for the remainder of the hands.
Future upper limb prostheses should be tested, and the results
should be provided to inform people about the specifications of
a
hand and to compare the new hand to current hands.[82] Future
research should be more focused on providing the specifications
of 3D-printed hand prostheses, e.g., the actuation force,
maximal
grip force, weight, battery life and durability, to allow for better
selection between the hands.
3D-printing technology used to print the upper limb prostheses
Every 3D-printing technique has it benefits and drawbacks.
These
are related to the accuracy of the printing process, possibility of
printing different materials and the cost of printing.
3D-printing technique
The majority of the hands (46) are made using the FDM 3D-
print-
ing technique. This technique is the primary technique used
worldwide because it uses a relatively cheap printer and is an
easy process. A variety of materials can be used, and in most
cases, post processing is not required. The downside of FDM is
the fact that very small details are difficult to make. FDM has
the
greatest layer height of all techniques used to print all
prostheses,
namely approximately 0.15 mm, which results in a rough
surface.
If overhanging structures need to be made, FDM printing
requires
support material, which then has to be subsequently removed.
SLS is a technique that uses a much more expensive printer but
provides a designer with more freedom with respect to shape. A
printed part is build up layer by layer by melting powder using
a
UV laser. The non-melted powder acts as a support material for
overhanging structures. The prostheses that are made using SLS
printing have a more free form shape compared with the hands
that are printed with the use of FDM printing. Smaller details
can
be printed using SLS compared with FDM because SLS has a
lower minimal layer height, namely approximately 100 lm,
result-
ing in a smoother surface compared with FDM. SLS printing
does
not necessarily require post-processing but results in a slightly
rough surface. This can be smoothened by polishing or adding a
coating. Both SLA and Polyjet printing have the advantage of
more design freedom and can print very small details. Both
have a very small minimal layer height of approximately 16 lm.
The downside of these techniques is that they both need post
processing to remove support material, and the material can
degrade over time as the photopolymers degrade due to
exposure to sunlight.[88] The prostheses made with FDM
printing
can be printed using a low cost home 3D-printer with a typical
cost of approximately $2000. Prostheses made with SLS, SLA
and
Polyjet printing are printed using a more expensive industrial
printer, especially the SLS and Polyjet printers. SLA printers
cost
approximately $5000, whereas the cost of SLS and Polyjet
printers
can range from $50,000 to $100,000.
Most of the hands do not require small details, which makes
FDM printing a suitable technique. Cheap and simple prostheses
Running head 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS        .docx
Running head 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS        .docx
Running head 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS        .docx
Running head 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS        .docx
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Running head 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS        .docx
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Running head 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS        .docx
Running head 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS        .docx
Running head 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS        .docx
Running head 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS        .docx
Running head 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS        .docx
Running head 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS        .docx
Running head 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS        .docx
Running head 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS        .docx
Running head 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS        .docx
Running head 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS        .docx
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Running head 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS        .docx
Running head 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS        .docx
Running head 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS        .docx
Running head 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS        .docx
Running head 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS        .docx
Running head 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS        .docx
Running head 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS        .docx
Running head 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS        .docx
Running head 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS        .docx
Running head 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS        .docx
Running head 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS        .docx
Running head 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS        .docx
Running head 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS        .docx
Running head 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS        .docx
Running head 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS        .docx
Running head 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS        .docx
Running head 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS        .docx
Running head 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS        .docx
Running head 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS        .docx
Running head 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS        .docx
Running head 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS        .docx
Running head 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS        .docx
Running head 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS        .docx
Running head 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS        .docx
Running head 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS        .docx
Running head 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS        .docx
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Running head 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS .docx

  • 1. Running head: 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS 1 3D PRINTED AND CONVENTIONAL PROSTHETIC LIMBS 2 SEE MY NOTES BELOW IN CAPS ANY SAFE ASSIGN PROBLEMS? OK GRADE FOR THIS DRAFT -- PAPER GRADE / grammar grade D / B- ACADEMIC FORMATTING References page NEEDS WORK -- LOW PASS In-text citations NOT ENOUGH CITING -- BODY PARAGRAPHS Synthesized NOT ACCOMPLISHED -- NO PASS Unified NEEDS WORK -- NOT IDENTIFYING BP THEMES CLEARLY Coherency NO DEVELOPMENT OF BP THEMES Transitions between BPs UNCLEAR CONNECTIONS OF ARGUMENTS -- ALSO YOU ARE MAKING AN ARGUMENT RATHER THAN
  • 2. INVESTIGATING A QUESTION Clarity of the writing WITH SO LITTLE DEVLEOPMENT OF IDEAS IT IS DIFFICULT TO KNOW WHAT THE SPECIFIC PURPOSE OF THIS SECTION IS Answered Section Question? NOT ACCOMPLISHED WITH ANY DETAIL Grammar - SEE RED FOR MISTAKES FOLLOW-UP WORK After completing the drafts of the first andsecond sections of your paper send—via attachment to an email—the paraphrased selections which the instructor BOLDED. Use the Paraphrase Check Work form explained in Module #10 webinar to share your bolded paraphrase and the original source material you used to create each paraphrase selection. SEE https://www.youtube.com/watch?v=dsUZQ2Kz7dI _____________________________________________________ _______________________________________________ 3D Printed and Conventional Prosthetic Limbs
  • 3. Name: Chanyez Chamberlain Institution: York College Date: 4/19/2018 INSERT PAGE BREAK BETWEEN COVER PAGE AND BODY OF THE PAPER MAIN QUESTION??? >>> Can 3D printed limbs be a more effective alternative to conventional prosthetic limbs? FOLLOW ARE NOT THE THREE SECTION QUESTIONS AS REQUIRED 1. Can 3D printed prosthetic limbs be more cost effective than conventional prosthetic limbs? FOCUS HERE IS ONLY ON COST -- 2. What is the cost of material for creating 3D printed limbs? 3. What is the cost of material for creating conventional prosthetic limb? 4. How does the cost of shipping 3D printed limbs versus conventional prosthetic limbs compare? 5. What is the accessibility of each for low-income families? MUST HAVE ONLY THREE SECTION QUESTIONS - NOT THE COMMON THEMES OF EACH BP IN THIS SECTION -- PLEASE REFER TO EXAMPLES Can 3D printed prosthetic limbs be more cost effective than conventional prosthetic limbs? USE TITLE CASE Technology creates a higher level of engagement where it is possible to achieve an improved level of effectiveness under which it is possible to improve the lives of individuals. <<,THIS IS CONFUSING -- NOT SURE WHAT THE POINT IS OR WHAT IT RELATES TO -- PLEASE CONSIDER RE- WRITING WHAT IS UNDERLINED ?>>>The conventional hypothetic limb is an artificial device, which replaces a missing leg, which might be lost in different ways such as trauma, congenital conditions or disease. They have a fundamental
  • 4. purpose where they are aimed at restoring standard functionality of an individual limb. The need for a more efficient limb has led to a more significant technology innovation where there is need to achieve a higher level of engagement based on the need for a transformative technology. <<,THIS NEEDS TO BE SHOWN -- HAS NOT AT THIS EARLY STAGE OF THE PAPER Printing 3D limbs have to provide a very different perspective where patients in need of artificial limbs can be fitted. 3D legs are more efficient, cost-effective and have less detrimental an individual health and well-being. WHERE DO YOU DEFINE WHAT THIS TECHOLOGY IS -- HOW IT DEVELOPED -- AND WHETHER THERE IS A NEED FOR IT -- THAT THERE IS A PROBLEM THAT NEEDS TO BE SOLVED -- SHOULD COME FIRST IN THIS PAPER What is the cost of material for creating 3D printed limbs? SPELL OUT TERM>>> PROFITABLE IS NOT THE SAME AS COST EFFECTIVE FOR THE PATIENT >>> 3D printed prosthetic limbs are more profitable than conventional prosthetic limbs. The cost aspect that is considered in this case involves the cost of production, purchase, and transportation. The 3D printed prosthetic limbs is a significant innovation, which has sought to create highly modernized limbs, which can help an individual carry out their activities without considerable challenge. The 3D printed limbs are particular to each patient since there is need to ensure that they are compatible with the system of the patient to achieve a higher level of efficiency (Ventola, 2014). NO FOCUS HERE -- RELATES TO MANY DIFFERENT THEMES -- IS NOT SYNTHESIZED -- NOT DEVELOPED -- NO PASS BP 1. PROFITABLITY 2. PRODUCTION COST 3. COST TO THE PATIENT 4. COST OF TRANSPORTING 5. IMPORTANT INNOVATION IN THIS TECHOLOGY -- 6. DESIGNEDN FOR EACH PATIENT
  • 5. What is the cost of material for creating conventional prosthetic limb? The cost of material for creating a conventional prosthetic limb is very high and thus fewer individuals can afford the conventional limbs since they involve many steps, which consume a lot of time during production time and therefore has a significant influence on the overall production cost for the traditional prosthetic limbs. The development of a single prosthetic limb based on the traditional approaches takes approximately a week. THERE IS NOT SUPPORT FOR THIS THEME -- THAT CONVENTIONAL ARTIFICIAL LIMBS ARE TOO COSTLY -- NO PROOF OF THIS CONTENTION - NOT SURE WHAT THE PURPOSE OF THIS BP IS -- NEEDS WORK -- NO PASS BP How does the cost of shipping 3D printed limbs versus conventional prosthetic limbs compare? The prosthetic need to be built and sized manually and thus to have mass production, there is a need for high labor, which automatically leads high cost of production where the cost of production is passed to patients, which limit their ability to create a higher engagement. <<<THIS IS AN OVERLY LONG TOPIC SENTENCE -- HOW CAN YOU SEE THIS THEME SIMPLY The cost of conventional prosthetic limb varies based on the type of the limb that is purchased. The cost varies from $5,000 and 100,000 for an advanced myoelectric arm controlled by muscle movements (Diment, Bergmann & Thompson, 2017). NO DEVELOPMENT -- NO SYNTHESIS - NO PASS BP What is the accessibility of each for low-income families? The 3D printed prosthetic limbs cut the cost and production time significantly. The 3D printed prosthetic limbs are expected to be produced at 80% faster rate than the conventional prosthetic limbs from one week to 1.5 days and developed efficiently with specific adaptability to specific patients. A printed 3D printed prosthetic limbs costs approximately $20, which is a tiny fraction of the total cost of conventional prosthetic limb, which costs up to $100,000. The 3D printed
  • 6. limbs are very useful based on high-level technology, which is essential in deciding its influence on the many patients who are in need of prosthetic limbs (Laszczak et al., 2015). NO SYNTHESIS -- LITTLE DEVELPMENT OF THIS BP THEME - - UNCLEAR WHAT THIS TOPIC SENTENCE MEANS -- WRITE CLEARLY AND DIRECTLY SO THAT YOUR READER UNDERSTAND THE TOPIC SENTENCE OF EACH BP >>> The low cost of 3D printed limbs has created a favorable environment where they are highly engaged access difference social classes including low-income families who can afford a 3D printed prosthetic limb. The cost when taking into consideration the training on how to use is still manageable and thus creates a higher level of engagement across different countries. NO PASS BP -- NOT SCCUDy There is need to focus on 3D printed limbs based on the high degree of efficiency and cost effectiveness which ensures that everyone who requires prosthetic limbs can get them at a very affordable cost. A more significant engagement provides a profoundly transformed focus where there is need to improve services delivery within the development of prosthetic limbs. INSERT PAGE BREAK -- DOUBLE SPACE THROUGHOUT References Diment, L., Bergmann, J., & Thompson, M. (2017). 3D printed upper-limb prostheses lack randomized controlled trials: a systematic review. INCOMPLETE Laszczak, P., Jiang, L., Bader, D. L., Moser, D., & Zahedi, S. (2015). Development and validation of a 3D-printed interfacial stress sensor for prosthetic applications. Medical Engineering and Physics, 37(1), 132-137. MISSING BIBLIO INFO Ventola, C. L. (2014). Medical applications for 3D printing: current and projected uses. Pharmacy and Therapeutics, 39(10), 704. MISSING INFO
  • 7. Cyborg beast: a low-cost 3d-printed prosthetic hand for children with upper-limb differences Zuniga et al. Zuniga et al. BMC Research Notes (2015) 8:10 DOI 10.1186/s13104-015-0971-9 Zuniga et al. BMC Research Notes (2015) 8:10 DOI 10.1186/s13104-015-0971-9 RESEARCH ARTICLE Open Access Cyborg beast: a low-cost 3d-printed prosthetic hand for children with upper-limb differences Jorge Zuniga1*, Dimitrios Katsavelis1, Jean Peck2, John Stollberg3, Marc Petrykowski1, Adam Carson1 and Cristina Fernandez4 Abstract Background: There is an increasing number of children with traumatic and congenital hand amputations or reductions. Children's prosthetic needs are complex due to their small size, constant growth, and psychosocial development. Families’ financial resources play a crucial role in the prescription of prostheses for their children, especially when private insurance and public funding are insufficient. Electric-powered (i.e., myoelectric) and body-powered (i.e., mechanical) devices have been developed to accommodate children’s needs, but the cost of maintenance and replacement represents an obstacle for many families. Due to the complexity and high cost of
  • 8. these prosthetic hands, they are not accessible to children from low-income, uninsured families or to children from developing countries. Advancements in computer-aided design (CAD) programs, additive manufacturing, and image editing software offer the possibility of designing, printing, and fitting prosthetic hands devices at a distance and at very low cost. The purpose of this preliminary investigation was to describe a low-cost three-dimensional (3D)-printed prosthetic hand for children with upper-limb reductions and to propose a prosthesis fitting methodology that can be performed at a distance. Results: No significant mean differences were found between the anthropometric and range of motion measurements taken directly from the upper limbs of subjects versus those extracted from photographs. The Bland and Altman plots show no major bias and narrow limits of agreements for lengths and widths and small bias and wider limits of agreements for the range of motion measurements. The main finding of the survey was that our prosthetic device may have a significant potential to positively impact quality of life and daily usage, and can be incorporated in several activities at home and in school. Conclusions: This investigation describes a low-cost 3D-printed prosthetic hand for children and proposes a distance fitting procedure. The Cyborg Beast prosthetic hand and the proposed distance-fitting procedures may represent a possible low-cost alternative for children in developing countries and those who have limited access to health care providers. Further studies should examine the functionality, validity, durability, benefits, and rejection rate of this type of low-cost 3D-printed prosthetic device. Keywords: 3D printing, Computer-aided design, Low-cost prosthesis, Custom-made prosthesis, Prosthesis
  • 9. for children * Correspondence: [email protected] 1Department of Exercise Science and Pre Health Professions, Creighton University, Omaha, NE 68178, USA Full list of author information is available at the end of the article © 2015 Zuniga et al.; licensee BioMed Central. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. mailto:[email protected] http://creativecommons.org/licenses/by/4.0 http://creativecommons.org/publicdomain/zero/1.0/ Zuniga et al. BMC Research Notes (2015) 8:10 Page 2 of 8 Background Children’s prosthetic needs are complex due to their small size, constant growth, and psychosocial develop- ment [1]. Familial financial resources play a crucial role in prescription of prostheses for children, especially when private insurance and public funding are insufficient [1]. Most upper-limb prostheses include a terminal device, with the objective to replace the missing hand or fingers. The cost of a body-powered prosthetic hand ranges from $4,000 to $20,000; depending on the mode of control,
  • 10. these devices require extensive fitting procedures to de- velop the terminal device and often include a complex system of cables and harnesses [2]. Electric-powered units (i.e., myoelectric) and mechanical devices (i.e., body- powered) have been improved to accommodate children’s needs, but the cost of maintenance and replacement rep- resents an obstacle for many families. Voluntary-closing upper-limb prosthetic devices are more suitable for chil- dren [1,3] and play a crucial role in improving gross motor development [1]. Currently, the most cost-effective option for pediatric populations is a passive prosthetic hook [1]; although functional, these devices have a high rejection rate, in part due to an unacceptable cosmetic appearance [4-6]. Most current prosthetics do not adapt to the normal growth of children’s limbs and require constant visits to health care providers for adjustments or replacement, which may lead to abandonment [1,6]. There has been an increase in the number of children born with congenital upper-limb deficiencies or ac- quired traumatic amputations during the past two de- cades [7-9]. It is estimated that, in the United States, more than 32,500 children suffer from a major pediatric amputation [8], and the Centers for Disease Control and Prevention estimates that about 1,500 children are born with upper-limb reductions in the United States each year [9]. Worldwide estimates for upper-limb re- ductions range from 4-5/10,000 to 1/100 live births [7]. There is a critical need for practical, easy-to-replace, customized, aesthetically appealing, low-cost prosthetic devices for children [10]. Figure 1 Prosthetic hand (Cyborg Beast). A: Top view (A1: Tensioner dia and B: Bottom view (B1: Forearm adjustable Velcro strap, B2: Hand adjustab Advancements in computer-aided design (CAD) pro-
  • 11. grams, additive manufacturing, and open source image editing software offer the possibility of designing, print- ing, and fitting prosthetic hands and other assistive de- vices at very low cost [11] (Figure 1). The development of low-cost prosthetic devices with practical and easy fit- ting procedures that can be performed at a distance would have a significant clinical and social impact on children around the world. Research Purpose The aim of this preliminary investigation was to briefly describe a low-cost three-dimensional (3D)-printed pros- thetic hand for children with upper-limb reductions and to propose a prosthesis fitting methodology that can be performed at a distance. We hypothesized that anthropo- metric measurement of the upper limbs taken from pho- tographs and processed by image editing software would not differ from anthropometric measurements taken dir- ectly on upper limbs. Methods Subjects Eleven children (two girls and seven boys, 3 to 16 years of age) with upper-limb reductions (one traumatic and eight congenital) participated in this study and were fit- ted with a low-cost 3D-printed prosthetic hand. Of the 11 participants, nine performed the laboratory visits and two were distance participants. A comparison between anthropometric measurements of the upper limbs taken from photographs and those taken directly on the upper limbs were reported for only nine local participants. In- clusion criteria included boys and girls from 3 to 17 years of age with unilateral carpus upper-limb reductions, missing some or all fingers, and wrist range of motion of the affected wrist greater than 20°. Exclusion criteria in- cluded upper extremity injury within the past month
  • 12. and any medical conditions that would contraindicate the use of our prosthetic hand prototype, such as skin abrasions and musculoskeletal injuries. The study was l, A2: Lift nylon cords, A3: Chicago screws, A4: Tension balance system) le Velcro strap). Zuniga et al. BMC Research Notes (2015) 8:10 Page 3 of 8 approved by the Creighton University Institutional Review Board and all the subjects completed a medical history questionnaire. All parents and children were informed about the study and parents signed a parental permission form. For children 6 to 16, an assent was explained by the principal investigator and signed by the children and their parents. Written informed consent from the parents was also obtained in order to publish the images shown in the present investigation. In addition, detailed safety guide- lines were given to the parents regarding the use and care of the prosthetic hand. 3D-printed prosthetic hand characteristics and usage The low-cost 3D-printed prosthetic hand named “Cyborg Beast” (Figure 1) was designed using a modeling software program (Blender 7.2, Blender Foundation, Amsterdam, Netherlands) and manufactured in the researcher’s labo- ratory using desktop 3D printers (Makerbot Replicator 2X, Makerbot Industries, Brooklyn, NY, and Ultimaker 2, Ultimaker B.V., Geldermalsen, The Netherlands). Elastic cords placed inside the dorsal aspect of the fingers provide passive finger extension. Finger flexion is driven by non- elastic cords along the palmar surface of each finger and is activated through 20-30° of wrist flexion. The result is a composite fist (flexing the fingers towards the palm) for gross grasp. The materials used for printing our prosthetic
  • 13. hand are polylactide (PLA) plastic and acrylonitrile buta- diene styrene (ABS). Other components of the prosthetic hand include Chicago screws of various sizes, 1 mm lift nylon cord, 1.5 mm elastic cord, Velcro, medical-grade firm padded foam, protective skin sock, and a dial ten- sioner system (Mid power reel M3, Boa Technology Inc., Denver, Colorado). The majority of these materials are available at local hardware stores or online. The present cost of materials is about $50 USD. The average time to fully assemble the prosthetic hand design is approximately 2. 5 hours. The weight of a fully assembled hand at a 140% of its original size is 184.2 grams. A similar device costs approximately $4,000 and weighs about 400 grams. The Cyborg Beast prosthetic hand is well suited for ac- tivities that involved the manipulation of light objects Figure 2 Three photographs of upper limbs. A: wrist extension (A1: non and C: Top view (C1: Non-affected hand length, C2: Non- affected hand wid C5: Affected hand length, C6: Affected hand width, C7: Affected forearm le using lateral, power (composite), and spherical prehen- sile patterns. Justification for the design and use of the 3D-printed prosthetic hand are low cost, easy usage, easy fitting, easy assembly, and visually appealing to children. The fitting procedures for the prosthetic hand require a few simple anthropometric measures of both limbs (Figure 2) to properly scale the prosthetic device. The files for the design are available online on the National Institutes of Health (NIH) 3D print exchange website (http://3dprint. nih.gov/discover/3dpx-000524) and Thingiverse (http:// www.thingiverse.com/thing:261462). All families and children participating in this study completed a short survey. The survey was developed to estimate the impact
  • 14. of this prosthetic device, including items related to qual- ity of life, daily usage, and types of activities performed. The survey has not been statistically validated, but pro- vides useful information related to usage and perception about improvements in quality of life. After approxi- mately one to three months of using the prosthetic hand, 11 children and their parents reported some increases in quality of life (four indicated this was significant and seven indicated a small increase), while one indicated no change. Nine children reported using the hand one to two hours a day, three reported using the prosthetic hand more than two hours, and one reported using the hand only when needed. Furthermore, children reported using the prosthetic hand just for fun (n = 10), for activities at home (n = 9), to play (n = 6), for school activities (n = 4), and to perform sports (n = 2). Proposed distance-fitting procedure The prosthetic hand (Figure 1) was designed to allow easy fitting with minimal anthropometric measurement requirements, which include hand length (tip of the middle finger to center of the wrist joint, Figure 2C1and C5), palm width (widest region of the palm above the base of the thumb, Figure 2C2), forearm length (center of the wrist joint to center of the elbow joint, Figure 2C3 and C6), forearm width at three-fourths (width of the forearm at proximal three-fourths of the length of the -affected, A2 affected), B: wrist flexion (B1: non-affected, B2: affected), th, C3: Non-affected forearm length, C4: Non-affected forearm width, ngth, and C8: Affected forearm width). http://3dprint.nih.gov/discover/3dpx-000524 http://3dprint.nih.gov/discover/3dpx-000524 http://www.thingiverse.com/thing:261462
  • 15. http://www.thingiverse.com/thing:261462 Zuniga et al. BMC Research Notes (2015) 8:10 Page 4 of 8 forearm proximal to the wrist, Figure 2C4 and C7), and range of motion of the wrists (extension and flexion, Figure 2A1 and A1). The proposed distance-fitting proced- ure involves extracting all these required measurements from three photographs of the upper limbs (Figure 2). To compare the anthropometric measurements taken directly from the subject’s upper limbs with those ex- tracted from photographs, a trained occupational the- rapist took the required anthropometric measurements directly from the subject’s upper limbs using a standard tape measure and goniometer. Three photographs of the upper limbs were taken as shown in Figure 2. All pic- tures included a ruler and were taken directly above the arms and included the entire forearm up to the elbow. To measure range of motion of the wrist, participants extended (Figure 2A) and flexed (Figure 2B) their wrists as far as possible. In addition, a reference line was drawn over the participant’s wrist joint of the non-affected hand (Figure 2C). An image editing program (ImageJ, version 1.46, NIH) was used to assess hand length, palm width, forearm length, forearm width at three-fourths, and range of motion of the wrists for flexion and exten- sion (Figure 2). All anthropometric measurements were taken directly from the subject’s upper limbs and com- pared to those extracted from photographs using an image editing program. All measurements were expressed in centimeters and calibrated using the ruler included in the image. Figure 3 Illustration of an image imported as plane and a Cyborg be After saving the images files with the calibrated mea-
  • 16. surements, they were imported as planes in Blender (Figure 3). Calibration of the metric scale on Blender was performed by changing the default unit (meter) to centimeters by adjusting the scale to 0.001. The image plane was resized to match the size of the 1 cm back- ground grid on Blender using the ruler on the imported image plane. The accuracy of the calibrations was con- firmed using the interactive ruler tool on Blender, per- forming several measurements over the ruler included in the image plane (Figure 3). After the image plane was cali- brated, a sizing chart was used to estimate the predicted size of the prosthetic hand expressed as a percentage of its original size (Figure 4). MakerWare software (Makerbot Industries, Brooklyn, NY) was used to size the prosthetic hand to the desired scale (%) using the scaling function. The sizing chart was developed to provide an easy method to scale the prosthetic hand for the user with no previous knowledge of CAD programs. For cases in which the cubic regression equation (Figure 4) was not able to accur- ately predict the correct size of the prosthetic hand due to differences in hand morphology, customized adjustments were made on Blender to ensure the proper fit. All the fit- ting procedures were performed with the assistance of an occupational hand therapist and a prosthetist. Thus, it is recommended to include clinical experts in the process of fitting the prosthetic device to avoid skin abrasions or breakdown due to improper fit. ast palm scale at 140% for a 16-year-old research participant. Figure 4 Sizing chart for Cyborg Beast prosthetic hand. Instructions: locate the child’s age in the bottom (X axis) and follow the line to the regression curve and then locate the intercepting line corresponding to the scale % on the left side (Y axis). Example:
  • 17. For a 5-year-old, the scale % of the Cyborg Beast would be 118% (±1.44%). This cubic regression equation was derived from a mixed sample of 11 children with ages ranging from 3 to 16 years of age. Zuniga et al. BMC Research Notes (2015) 8:10 Page 5 of 8 Statistical Analysis Anthropometric Measurements Seven separate two-way repeated measures ANOVAs [2 × 2; hand (affected versus non-affected) × fitting pro- cedures (direct versus photographs)] were performed to analyze the data. In addition, the data have also been presented using the method of Bland and Altman as described by previous investigations [12-14]. Pearson product–moment correlation coefficient was calculated to examine the correlations between the difference and the mean of the difference from the mean values shown in the Bland and Altman plots. A p-value of ≤0.05 was considered statistically significant for all comparisons. Results The results of the two-way repeated measures ANOVAs showed no significant mean difference between the an- thropometric measures taken directly on the subject’s upper limbs and those taken from the photographs (Table 1). There were no significant two-way interactions Table 1 Mean (±SD) for anthropometric measures and range Measurements Non-affected Direct Hand Length (cm) 13.83 ± 2.44 Palm Width (cm) 7.00 ± 1.20
  • 18. Forearm Length (cm) 18.94 ± 3.88 Forearm Width (cm) 6.23 ± 0.85 Wrist Range of Motion Flexion (°) 76.00 ± 10.27 Wrist Range of Motion Extension (°) 76.44 ± 5.7 The results of the two-way repeated measures ANOVAs showed no significant (p >0 the subject’s upper limbs and those taken from photographs. There were no signifi x fitting procedures. There was a significant main effect for hand (affected versus n versus photographs). for repeated measures ANOVAs performed for hand × fitting procedures. There was a significant main effect, however, for hand (affected versus non-affected), with no significant main effect for fitting procedures (direct versus photographs). When the relationship between scale of the prosthetic hand (%) versus age (years) was analyzed, our results indicated that the cubic model was the best-fit for our sample (Figure 4). The main finding of the survey was that our prosthetic device may have a significant potential to positively impact quality of life and daily usage, and can be incorporated in several activities at home and in school. The Bland and Altman plots (Figure 5) show 95% limits of agreements for the anthropometric measurements of the affected hand and measures of range of motion. The aver- age discrepancy (represented by a solid line in Figure 5) for the lengths and widths of the hand and forearm re- sulted in values close to zero, indicating no major bias. The limits of agreement (represented by a dotted line in Figure 5) are narrow and show that these measures tend to be within 5 mm of each other. The range of motion
  • 19. of motion of the wrists Affected Photographs Direct Photographs 13.44 ± 1.73 4.02 ± 1.07 4.25 ± 1.15 6.91 ± 0.95 4.50 ± 0.90 4.54 ± 0.66 18.94 ± 4.16 16.29 ± 3.41 16.69 ± 4.09 6.47 ± 1.12 5.57 ± 0.77 5.54 ± 0.59 75.33 ± 11.01 56.44 ± 13.15 59.76 ± 13.95 76.00 ± 6.96 45.67 ± 33.47 43.56 ± 33.29 .05) mean difference between the anthropometric measures taken directly on cant two-way interactions for repeated measures ANOVAs performed for hand on-affected), with no significant main effect for fitting procedures (direct Figure 5 Bland and Altman plots for anthropometric and range of motion measurements taken directly from the subject’s upper limbs and those taken from photographs. Zuniga et al. BMC Research Notes (2015) 8:10 Page 6 of 8 measurements, however, presented a small bias (average discrepancy values greater than zero) and wider limits of agreements, with about 10° difference between methods.
  • 20. No trends were found and the correlations between the difference and mean of the difference were not significant, ranging from 0.04 to 0.53 (Figure 5). Discussion The results of the present investigation indicated that there were no mean differences between anthropometric measures taken directly from the subject’s upper limbs and those extracted from photographs (Table 1). The Bland and Altman plots (Figure 5) show no major bias and narrow limits of agreements for lengths and widths and small bias and wider limits of agreements for the range of motion measurements. Furthermore, the survey indicated that the prosthetic device may have a signifi- cant potential to positively impact quality of life and daily usage in several activities at home or school. The fitting procedures of our prosthetic hand design require minimal anthropometric measurements of the upper limbs for proper scaling and fitting. Most fitting proce- dures required for prosthetic hands include wrap cast- ing using plaster bandages placed over the affected limb [2]. More recently, 3D scanning has also been used for the development of different type of prostheses and or- thoses [11,15,16]. Casting procedures require the physical presence of the individual needing the prosthetic hand and the health care professional in the same physical loca- tion, which may not be possible for patients living in rural or isolated areas. 3D scanning procedures required so- phisticated equipment and technical knowledge to per- form the measurements. Furthermore, both techniques require the patient to visit the health care facilities for proper fitting procedures. The results from the present investigation provide a novel distance-fitting procedure for a low-cost 3D-printed prosthetic hand for children with upper-limb differences.
  • 21. Image editing software to extract information from digital images has been used for a wide range of disciplines, in- cluding molecular biology and archeology [17,18]. The present investigation applied image editing techniques to extract anthropometric data and 3D modeling applications to develop a novel distance-fitting procedure. The recent popularity and low cost of desktop 3D printers makes the prosthetic hand described in the current investi- gation readily accessible. The proposed distance-fitting procedures can make this device accessible to a great number of children in need of this type of device around the globe. These procedures, however, must be performed with caution, since inaccurate scaling or significant errors in the measurements could affect the function or fitting of the 3D-printed prosthetic hand. Overall, this low- cost prosthetic hand and the ability to fit this device at Zuniga et al. BMC Research Notes (2015) 8:10 Page 7 of 8 a distance represent a low-cost alternative for children in developing countries and children from uninsured or economically disadvantaged families. Conclusion This investigation provides a description of a low-cost 3D-printed prosthetic hand for children and proposes a distance-fitting procedure. The Cyborg Beast prosthetic hand and the proposed distance-fitting procedure repre- sent a possible low-cost alternative for children in devel- oping countries and those with little or no access to health care providers. Our prosthetic device may have a significant potential to positively impact quality of life and daily usage. Further studies should examine the functionality, validity, durability, benefits, and rejection rate of this low-cost 3D-printed hand design. Consent
  • 22. All parents and children were informed about the study and signed a parental permission. For children 6 to 16, an assent was explained by the principal investigator and signed by the children and their parents. Written informed consent from the parents was obtained in or- der to publish the images shown in the present inves- tigation. Furthermore, detailed safety guidelines were given to the parents regarding the use and care of the prosthetic hand. Abbreviations 3D: Three-dimensional; CAD: Computer-aided design; ABS: Acrylonitrile butadiene styrene; PLA: Polylactide; ANOVA: Analysis of variance. Competing interests JZ is the designer of the prosthetic hand Cyborg Beast and partially funded this study with start-up funds. DK, JS, AC, and MP participated in the refinement and improvement of the prosthetic hand. Author’s information JZ is an Assistant Professor in the Department of Exercise Science and Pre Health professions at Creighton University, director of the 3D Research & Innovation Laboratory, and co-director of the Human Movement Laboratory. JZ is a member of the Association of Children’s Prosthetic- Orthotic Clinics and the American College of Sports Medicine. DK is an Assistant Professor in the Department of Exercise Science and Pre Health professions and affiliated with the Physical Therapy
  • 23. Department at Creighton University. DK is a member of the American Society of Biomechanics and co-director of the Human Movement Laboratory. JP is an occupational therapist, certified hand therapist at CHI Health Creighton University Medical Center and an adjunct faculty at the Department of Occupational Therapy at Creighton University. JS is a doctoral student from the Department of Occupational Therapy at Creighton University. MP is an undergraduate student from the Department of Exercise Science and Pre Health Professions at Creighton University. AC is an undergraduate student from the Department of Exercise Science and Pre Health Professions at Creighton University. CF is an associate Professor of Pediatrics at Creighton University. CF is Children’s Physicians Medical Director-HEROES Program and an Associate Program Director for UNMC/Creighton University/Children’s Hospital and Medical Center. Authors’ contributions All the authors reviewed and contributed to the manuscript. JZ was the originator of the study concept and design, study methodology, and manuscript draft. DK, JP, JS, and MP were involved in data collection. DK, JP, and MP contributed to design improvements of the prosthetic hand. MP printed most of the parts of the prosthetic hands for the research
  • 24. participants and performed substantial improvements. JZ, JP, AC, and MP assembled the prosthetic hands. DK performed part of the data analysis. All authors read and approved the final manuscript. Acknowledgement We would like to thank Richard Van As and Ivan Owen for their contribution in the development of the 3D-printed prosthetic hand named Robohand. Special thanks to all members of the online group “e-NABLE” (http:// enablingthefuture.org/) for their feedback and constant support. We also would like to thank the parents and their children for participating in our study. Thanks to the students from the 3D Research & Innovation Laboratory at Creighton University (http://www.cyborgbeast.org/) who helped with data collection. This study was funded by the NASA Nebraska Space Grant Office. Author details 1Department of Exercise Science and Pre Health Professions, Creighton University, Omaha, NE 68178, USA. 2CHI Health Creighton University Medical Center, Omaha, NE 68131, USA. 3Department of Occupational Therapy, Creighton University, Omaha, NE 68178, USA. 4Children’s Hospital and Medical Center, Omaha, NE 68114, USA. Received: 8 August 2014 Accepted: 31 December 2014
  • 25. References 1. Krebs DE, Edelstein JE, Thornby MA. Prosthetic management of children with limb deficiencies. Phys Ther. 1991;71:920–34. 2. Bray JJ. University of California Los Angeles. Prosthetics- Orthotics Education Program.: Prosthetic principles, upper extremity amputations : fabrication and fitting principles. Los Angeles: Prosthetics-Orthotics Education Program, Division of Orthopedic Surgery, University of California, Los Angeles; 1970. 3. Shaperman J, Leblanc M, Setoguchi Y, McNeal DR. Is body powered operation of upper limb prostheses feasible for young limb deficient children? Prosthetics Orthot Int. 1995;19:165–75. 4. Marshall JG. Partial hand and functional prosthesis. JACPOC. 2000;6:1. 5. Scotland TR, Galway HR. A long-term review of children with congenital and acquired upper limb deficiency. J Bone Joint Surgery British Vol. 1983;65:346–9. 6. Davids JR, Wagner LV, Meyer LC, Blackhurst DW. Prosthetic management of children with unilateral congenital below-elbow deficiency. J Bone Joint Surg. 2006;88:1294–300.
  • 26. 7. Bethge M, von Groote P, Giustini A, Gutenbrunner C. The World Report on Disability: a challenge for rehabilitation medicine. Am J Phys Med Rehabil. 2014;93:S4–11. 8. Cignini P, Giorlandino C, Padula F, Dugo N, Cafa EV, Spata A. Epidemiology and risk factors of amniotic band syndrome, or ADAM sequence. J Prenatal Med. 2012;6:59–63. 9. Parker SE, Mai CT, Canfield MA, Rickard R, Wang Y, Meyer RE, et al. Updated National Birth Prevalence estimates for selected birth defects in the United States, 2004–2006. Birth Defects Res Part A, Clin Mole Teratol. 2010;88:1008–16. 10. Resnik L. Development and testing of new upper-limb prosthetic devices: research designs for usability testing. J Rehabil Res Dev. 2011;48:697–706. 11. Rengier F, Mehndiratta A, von Tengg-Kobligk H, Zechmann CM, Unterhinninghofen R, Kauczor HU, et al. 3D printing based on imaging data: review of medical applications. Int J Comput Assist Radiol Surg. 2010;5:335–41. 12. Bland JM, Altman DG. Statistical methods for assessing agreement between
  • 27. two methods of clinical measurement. Lancet. 1986;1:307–10. 13. McLaughlin P. Testing agreement between a new method and the gold standard-how do we test? J Biomech. 2013;46:2757–60. 14. Howell DC. Statistical methods for psychology. 4th ed. Belmont: Wadsworth Publishing Company; 1997. 15. Vera C, Barrero C, Shockley W, Rothenberger S, Minsley G, Drago C. Prosthetic Reconstruction of a Patient with an Acquired Nasal Defect Using http://enablingthefuture.org/ http://enablingthefuture.org/ http://www.cyborgbeast.org/ Zuniga et al. BMC Research Notes (2015) 8:10 Page 8 of 8 Extraoral Implants and a CAD/CAM Copy-Milled Bar. J Prosthodont. 2014;23:582–7. 16. Dombroski CE, Balsdon ME, Froats A. The use of a low cost 3D scanning and printing tool in the manufacture of custom-made foot orthoses: a preliminary study. BMC Res Notes. 2014;7:443. 17. Doneus M, Verhoeven G, Atzberger C, Wess M, Ruš M. New ways to extract archaeological information from hyperspectral pixels. J Archaeol Sci. 2014;52:84–96.
  • 28. 18. Hartig SM: Basic image analysis and manipulation in ImageJ. Current protocols in molecular biology/edited by Frederick M Ausubel [et al.] 2013, Chapter 14:Unit14 15. Submit your next manuscript to BioMed Central and take full advantage of: • Convenient online submission • Thorough peer review • No space constraints or color figure charges • Immediate publication on acceptance • Inclusion in PubMed, CAS, Scopus and Google Scholar • Research which is freely available for redistribution Submit your manuscript at www.biomedcentral.com/submit AbstractBackgroundResultsConclusionsBackgroundResearch PurposeMethodsSubjects3D-printed prosthetic hand characteristics and usageProposed distance-fitting procedureStatistical AnalysisAnthropometric MeasurementsResultsDiscussionConclusionConsentAbbreviatio nsCompeting interestsAuthor’s informationAuthors’ contributionsAcknowledgementAuthor detailsReferences Full Terms & Conditions of access and use can be found at http://www.tandfonline.com/action/journalInformation?journalC ode=iidt20
  • 29. Disability and Rehabilitation: Assistive Technology ISSN: 1748-3107 (Print) 1748-3115 (Online) Journal homepage: http://www.tandfonline.com/loi/iidt20 3D-printed upper limb prostheses: a review Jelle ten Kate, Gerwin Smit & Paul Breedveld To cite this article: Jelle ten Kate, Gerwin Smit & Paul Breedveld (2017) 3D-printed upper limb prostheses: a review, Disability and Rehabilitation: Assistive Technology, 12:3, 300-314, DOI: 10.1080/17483107.2016.1253117 To link to this article: https://doi.org/10.1080/17483107.2016.1253117 © 2016 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group Published online: 02 Feb 2017. Submit your article to this journal Article views: 3121 View related articles View Crossmark data Citing articles: 4 View citing articles http://www.tandfonline.com/action/journalInformation?journalC
  • 30. ode=iidt20 http://www.tandfonline.com/loi/iidt20 http://www.tandfonline.com/action/showCitFormats?doi=10.108 0/17483107.2016.1253117 https://doi.org/10.1080/17483107.2016.1253117 http://www.tandfonline.com/action/authorSubmission?journalCo de=iidt20&show=instructions http://www.tandfonline.com/action/authorSubmission?journalCo de=iidt20&show=instructions http://www.tandfonline.com/doi/mlt/10.1080/17483107.2016.12 53117 http://www.tandfonline.com/doi/mlt/10.1080/17483107.2016.12 53117 http://crossmark.crossref.org/dialog/?doi=10.1080/17483107.20 16.1253117&domain=pdf&date_stamp=2017-02-02 http://crossmark.crossref.org/dialog/?doi=10.1080/17483107.20 16.1253117&domain=pdf&date_stamp=2017-02-02 http://www.tandfonline.com/doi/citedby/10.1080/17483107.201 6.1253117#tabModule http://www.tandfonline.com/doi/citedby/10.1080/17483107.201 6.1253117#tabModule REVIEW 3D-printed upper limb prostheses: a review Jelle ten Kate, Gerwin Smit and Paul Breedveld Department of BioMechanical Engineering, Delft University of Technology, Delft, The Netherlands ABSTRACT Goal: This paper aims to provide an overview with quantitative information of existing 3D-printed upper limb prostheses. We will identify the benefits and drawbacks of
  • 31. 3D-printed devices to enable improve- ment of current devices based on the demands of prostheses users. Methods: A review was performed using Scopus, Web of Science and websites related to 3D-printing. Quantitative information on the mechanical and kinematic specifications and 3D-printing technology used was extracted from the papers and websites. Results: The overview (58 devices) provides the general specifications, the mechanical and kinematic specifications of the devices and information regarding the 3D- printing technology used for hands. The overview shows prostheses for all different upper limb amputation levels with different types of control and a maximum material cost of $500. Conclusion: A large range of various prostheses have been 3D- printed, of which the majority are used by children. Evidence with respect to the user acceptance, functionality and durability of the 3D-printed hands is lacking. Contrary to what is often claimed, 3D-printing is not necessarily cheap, e.g., injection moulding can be cheaper. Conversely, 3D-printing provides a promising possibility for individualization, e.g., personalized socket, colour, shape and size, without the need for adjusting the production machine. � IMPLICATIONS FOR REHABILITATION � Upper limb deficiency is a condition in which a part of the upper limb is missing as a result of a con- genital limb deficiency of as a result of an amputation. � A prosthetic hand can restore some of the functions of a missing limb and help the user in perform- ing activities of daily living. � Using 3D-printing technology is one of the solutions to
  • 32. manufacture hand prostheses. � This overview provides information about the general, mechanical and kinematic specifications of all the devices and it provides the information about the 3D- printing technology used to print the hands. ARTICLE HISTORY Received 18 July 2016 Revised 6 October 2016 Accepted 23 October 2016 KEYWORDS 3D-printing; hand; prostheses; specifications; upper limb Introduction Over the last 5 years, significant development has occurred in 3D- printing of upper limb prostheses. All over the world people are designing and printing new devices that can easily easy fit a human arm. Scientific papers have been published regarding research in the field of 3D-printed upper limb prostheses.[1–7] People are developing prostheses individually, and large commun- ities have been established. Most of the development of 3D- printed prostheses began after the establishment of the global community e-NABLE. This community has grown into a worldwide movement of tinkerers, engineers, 3D-printing enthusiasts, occu- pational therapists, university professors, designers, parents, fami- lies, artists, students, teachers and people who have developed
  • 33. 3D-printed prostheses.[8] It all started with the idea of developing a cheap hand prosthesis.[9] The cost of a commercial body-pow- ered prosthetic hand can range from $4000 to $10,000,[10] and the cost of an externally powered prosthetic hand can range from $25,000 to $75,000.[10,11] The beginning of the development of a 3D-printed hand prosthesis for people who cannot afford an expensive commercial prosthesis resulted in the Robohand, as shown in Figure 1. 3D-printing is an additive manufacturing technique. Products are built up layer by layer instead of removing material from a large piece of material, such as in CNC milling. 3D-printing has several advantages compared with other manufacturing techni- ques [12,13]: � It is possible to make products out of one part; therefore, no assembly is required. � There is large design freedom; therefore, highly complex geometries can be made. � Designs can easily be personalized and customized; there is no need to change the machine. � Parts can be produced cheaply and quickly from idea to end product, which gives the advantage of rapid design improvements. 3D-printing also has disadvantages compared to other manu- facturing techniques [14,15]: � It is hard to predict the mechanical properties. The result-
  • 34. ing strength of a part is highly dependent on the CONTACT Gerwin Smit [email protected] Department of Biomechanical Engineering, Delft University of Technology, Mekelweg 2, Delft 2628 CD, The Netherlands � 2016 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way. DISABILITY AND REHABILITATION: ASSISTIVE TECHNOLOGY, 2017 VOL. 12, NO. 3, 300–314 http://dx.doi.org/10.1080/17483107.2016.1253117 http://orcid.org/0000-0002-8160-3238 http://orcid.org/0000-0002-7235-1657 http://creativecommons.org/licenses/by-nc-nd/4.0/ fabrication method, and various parameters can be selected depending on the printing orientation. � The accuracy is highly affected by material shrinkage, dif- ferent machine parameters and errors induced by the CAD/CAM software as well as post processing. � The size of an object is limited by the size of the printer. Very large objects cannot be made with current 3D-print- ing technology.
  • 35. � 3D-printers can work with a limited amount of materials compared with conventional manufacturing, which can work with nearly any material. Problem Although many upper limb prostheses are being 3D-printed all over the world, to the authors’ knowledge, there are no specific design guidelines and there is no overview of all of the various devices that have been designed and 3D-printed so far. Some sci- entific research is ongoing in the field of 3D-printing upper limb prostheses, but currently, most of the 3D-printing of these devices is performed by trial and error. Goal Our goal is to provide an overview with quantitative information about existing 3D-printed upper limb prostheses. We will identify the benefits and drawbacks of 3D-printed devices to enable improvements of current devices based on the demands of pros- theses users. Methods Currently, little information on 3D-printed hand prostheses is available in the peer-reviewed literature. Therefore, information from Internet databases and websites focused on 3D-printing were included. The review consists of two parts: first, the Scopus
  • 36. and Web of Science databases were used; second, an Internet search was performed on three websites: � www.enablingthefuture.org � www.3dprint.com � www.3ders.org Three websites were used. The first website contains a large database of 3D-printed hand prostheses that have been devel- oped for the worldwide community e-NABLE. The second and third websites provide the most up to date information in the field of 3D-printing. Only unique devices identified through the literature and through website searches were included. Devices based on similar designs were excluded. Only results in the English language were used in this literature review. The database and Internet searches were carried out using the fol- lowing keywords: 3D-printing, rapid prototyping, hand, upper limb, prosthetic, prosthetics and prostheses. Quantitative infor- mation on the mechanical and kinematic specifications and 3D-printing technology used were extracted from the papers and websites. Exclusion and inclusion criteria Partial finger prostheses and custom prostheses made for han- dling a specific tool were excluded in the overview. Articles related to the topic that were not found with the search criteria but found from references in other papers were included. Results The review resulted in an overview with seven devices found in the scientific literature and 51 devices found on the Internet. The results are presented in three tables. The first table con- tains general specifications and the mechanical characteristics of
  • 37. the hands. The second table provides information about the kinematics of the hands. The third table provides information from the field of 3D-printing technology that regarding the hands. Each table is divided into two parts. The first part shows the 3D-printed upper limb prostheses found in the scientific lit- erature. The second part of the table shows the devices found from the Internet search. Several specifications or characteristics from the prostheses are unknown and are identified with an “–”symbol in the tables. Mechanical specifications Type of prosthesis and type of actuation The general specifications of the prostheses and mechanical speci- fications of the fingers are shown in Table 1. Some examples of the 3D-printed upper limb prostheses are shown in Figure 2. Table 1 shows the type of prosthesis. These can be specified as three different levels of prostheses: � Hand (18): The amputation level is a partial hand. � Forearm (37): The amputation level is below the elbow. � Upper arm (3): The amputation level is above the elbow. The various types of actuation for the various types of pros- theses are shown in Figure 3. All prostheses for people with partial hand loss are body powered. There are four actuation methods for forearm prostheses: two are passive static, one is passive adjustable, 14 are body powered and 20 are externally powered. For externally powered prostheses, 19 are electrically powered and one is powered by pressurized air. All the upper arm prostheses are externally powered and all are electrically powered. Figure 1. Robohand: the hand that was the inspiration for the
  • 38. development of the global community. Image reproduced with permission from Brod Marsh on behalf of Robohand Australia see http://www.robohand.net/wp- content/uploads/ 2013/03/2013-03-29-11-10-58-b.jpg, i.e., the copyright holder. 3D-PRINTED UPPER LIMB PROSTHESES: A REVIEW 301 http://www.enablingthefuture.org http://www.3dprint.com http://www.3ders.org http://www.robohand.net/wp-content/uploads/2013/03/2013-03- 29-11-10-58-b.jpg http://www.robohand.net/wp-content/uploads/2013/03/2013-03- 29-11-10-58-b.jpg Type of actuation and type of control The different types of actuation for the different types of control are shown in Figure 4. The two passive static prostheses [37,50] are a decorative prosthesis, as opposed to the other prostheses, which are more practical and more functional prostheses. One of the prosthesis is passive adjustable.[57] This prosthesis has four rigid fingers and an adjustable thumb that is made by modifying an existing prosthetic hook. The 32 body-powered prostheses can be divided into prostheses controlled by flexing the thumb (1), flexing the wrist (17), flexing the elbow (4) and through the use of a shoulder harness (4), and for six prostheses, the actuation method was not mentioned. It is unknown how these devices are actuated. Presumably, they can be used with a shoulder harness because they all make use of one output cable that controls all the fingers. There were 23 prostheses found that are externally
  • 39. powered from, two of which are controlled by electroencephalog- raphy (EEG), 20 of which are controlled by electromyography (EMG) and one of which is voice controlled.[24] Table 1. General specifications and mechanical specifications of the 3D-printed hand prostheses. Type of Prosthesis Type of Actuation Type of Control Weight (g) Force distribution Flexor Extensor Prostheses found in the scientific literature Andrianesis’ hand [1], Figure 2(a) Forearm EP EMG 350 Independent Cables/cords ML Bahari’s hand [2] Forearm EP EMG – Independent ML Cables/cords Gosselin’s hand [3], Figure 2(b) Forearm BP SH – Distributed Cables/cords Cables/cords Gretsch’ HAND [4] Forearm EP EMG 240 Independent Cables/cords Elastic cords Groenewegen’s hand [5] Forearm BP – 71 Distributed ML CM O’Neill’s HAND [6] Forearm EX EMG 960 Independent Cables/cords Cables/cords Simone’s hand [7] Forearm EP EMG – Independent Cables/cords Cables/cords Prostheses found by performing an internet search 3D-printed prosthesis ecuador [16] Forearm EP EMG – Independent Cables/cords Cables/cords Adjustable thumb [17] Hand BP Wrist – Equal Cables/cords Elastic cords Biohand [18] Forearm EP EMG – Independent ML ML Bionico hand [19] Forearm EP EMG – Independent Cables/cords Cables/cords Cyborg arm [20] Forearm BP Elbow – Equal Cables/cords Elastic cords
  • 40. Cyborg beast [21], Figure 2(c) Hand BP Wrist 1.315 Equal Cables/cords Elastic cords Cyborg beast with I.W.M. [22] Hand BP Wrist – Equal Cables/cords Elastic cords Dextrus EMG [23] Forearm EP EMG 450 Independent Cables/cords Cables/cords DIY prosthetic hand & forearm [24] Forearm EP Voice – Independent Cables/cords Cables/cords Falcon hand V1 [25] Hand BP Wrist – Equal Cables/cords Elastic bands Falcon hand V2 [26] Hand BP Wrist – Equal Cables/cords Elastic bands Flexy arm [27] Forearm BP Elbow – Equal Cables/cords CM Flexy hand [28] Forearm BP – – Equal Cables/cords CM Flexy hand 2 [29] Hand BP Wrist – Equal Cables/cords CM Flexy hand – filaflex remix [30] Forearm BP – – Equal Cables/cords CM Galileo hand [31] Forearm BP SH – Equal Cables/cords Elastic cords HACKberry [32] Forearm EP EMG – Independent ML ML Handiii [33] Forearm EP EMG – Independent ML ML Handiii COYOTE [34] Figure 2(d) Forearm EP EMG 750 Independent ML ML Hollies hand [35] Hand BP Wrist – Equal Cables/cords CM InMoov 2 hand [36] Forearm EP EMG 450 Independent ML ML IVIANA 2.0 [37] Figure 2(e) Forearm PS N/A – N/A N/A N/A JD-1 [38] Forearm BP – – Distributed Cables/cords CM K-1 [39] Hand BP Wrist – Equal Cables/cords Elastic cords Latest bionic arm [40] Forearm EP EMG 250 Independent Cables/cords CM Limbitless Arm [41] Upper arm EP EMG – Equal Cables/cords CM Manu print (Re hand) [42] Forearm BP – – Distributed Cables/cords Elastic cords Mind controlled robotic hand [43] Upper arm EP EEG – Independent Cables/cords Cables/cords
  • 41. Muscle robot hand [44] Forearm EP EMG – Independent Compressed air CM Not impossible [45] Forearm BP Elbow – Equal Cables/cords Elastic cords Nu hand [46] Forearm EP EMG – Independent Cables/cords Elastic cords Odysseus hand [47] Hand BP Wrist – – Cables/cords Elastic cords One-hinged Cyborg beast [48] Hand BP Wrist – Equal Cables/cords Elastic cords Prosthetic/robotic hand [49] Forearm BP – – Equal Cables/cords Elastic bands Pr�otesis Cosm�etica [50] Forearm PS N/A – N/A N/A N/A Raptor hand [51] Hand BP Wrist – Equal Cables/cords Elastic cords Raptor reloaded [52] Hand BP Wrist – Equal Cables/cords Elastic cords RIT arm [53] Forearm BP Elbow – Equal Cables/cords Elastic cords Roboarm [54] Upper arm EP EEG 2000 Independent Cables/cords Cables/cords Robohand [55] Hand BP Wrist – Equal Cables/cords Elastic cords Robot hand [56] Forearm EP EMG – Equal Cables/cords CM Scand [57] Figure 2(f) Forearm PA N/A – N/A N/A N/A Snap-together Robohand [58] Hand BP Wrist – Equal Cables/cords Elastic cords Tact [59] Forearm EP EMG 350 Independent Cables/cords Elastic bands Talon flextensor 1.0 [60] Hand BP Wrist – Equal Cables/cords Elastic cords Talon hand 2.0 [61] Hand BP Wrist – Equal Cables/cords Elastic cords Tenim hand [62] Forearm BP SH – Distributed Cables/cords Cables/cords The lucky paw prosthetic hand [63] Hand BP Finger – Equal
  • 42. Cables/cords Elastic cords Victory hand [64] Forearm BP SH – Distributed ML ML Youbionic [65] Forearm EP EMG – Independent ML ML Zero point frontiers [66] Hand BP Wrist – Equal Cables/cords Elastic cords BP: body-powered; EP: externally powered; PS: passive static; PA: passive adjustable; SH: shoulder harness; ML: mechanical linkages; CM: compliant mechanisms. 302 J. T. KATE ET AL. Weight The weight of only 11 of the 58 printed upper limb prostheses is specified, as shown in Table 2. The lightest device was devel- oped by M. Groenewegen [5] and weighs 71 g. The heaviest device is the Roboarm developed by Unlimited Tomorrow,[54] with a weight of 2000 g. The remainder of the hands have a weight ranging from 132 g [21] to 960 g,[6] with most of them (6) ranging from 240 g [4] to 450 g.[23,36] The weight of some of the devices given in the table is not the total weight of the prosthesis: � Although the Cyborg Beast has the second lowest weight (131.5 g) compared with the others, this weight is of a prosthesis for a 3-year child. To print this hand for a 16- year-old child, it should be scaled by 140%, which would result in a weight of 184.2 g.[67] � The Roboarm is a lot heavier than the other prostheses because it is a complete arm. The developers state that it is made from 2 kg of plastic. Therefore, the total weight Figure 2. Examples of 3D-printed upper limb prostheses (a)
  • 43. Andrianesis’ Hand: an externally powered forearm prosthesis. Andrianesis and Tzes [1], with permission of Springer. (b) Gosselin’s hand: a body powered forearm prosthesis. Original source: Laliberte et al. No changes made. Reproduced under creative commons attribution 3.0 [3]. (c) Cyborg beast: a body-powered hand prosthesis. Published with permission of Zuniga [21]. (d) Handiii COYOTE: an externally powered forearm prosthesis. #exiii, Inc. published with permission [34]. (e) IVIANA 2.0: a passive forearm prosthesis. Published with permission of Evan Kuester [37]. (f) Scand: a passive adjustable forearm prosthesis. Original source http://www.instructables.com/id/3D-Printing-Prosthetic-Hand- Make-it-Real-Challen/Scott Allen. No changes made. Reproduced under creative commons attribution 3.0 [57]. Figure 3. Almost two-thirds of the devices are forearm prostheses from which slightly more than half of the devices are externally powered. 3D-PRINTED UPPER LIMB PROSTHESES: A REVIEW 303 http://www.instructables.com/id/3D-Printing-Prosthetic-Hand- Make-it-Real-Challen/Scott will be even greater due to the weight of the motors and electronic parts. � The advanced, low-cost prosthetic arm developed by C. O’Neill weighs 960 g. This includes a socket, but excludes the haptic feedback sensors.[6] � The weight of the prosthesis developed by Andrianesis et al. [1] is 350 g, including a cosmetic glove, but exclud-
  • 44. ing the 180-g battery. Force distribution The various types of force distribution between the fingers of each hand are shown in Figure 5. The total number of prostheses shown in this figure is 55. The three passive prostheses are excluded. The specifications related to force distribution between the fingers are specified for only a small portion of the hands. For the hands in which the force distribution was not specified, we determined the specifications based on videos and images. The force distribution between the fingers is equal for the majority of hands (28): when the hand is actuated, the force is equally distrib- uted over the fingers. The minority of the prostheses (6) have fin- gers with force distribution over the fingers, which ensures an adaptive grasp. In these prostheses, the other fingers can still apply a force when some of the fingers are halted by an object. The remainder of the prostheses (21) have fingers with independ- ent force, with one motor per finger. This also enables an adap- tive grasp and enables a large variety grasp types. Type of flexor The different types of flexors used to close the hand are shown in Figure 6. All the body-powered prostheses found to make use of the voluntary closing principal. Voluntary closing devices close when they are actuated and return to their natural open position when the force is released. The majority of devices (45) use cables or non-elastic cords to close the hand. When flexing the wrist or
  • 45. elbow, the cables or cords attached to the end of the fingers ensure that they make a closing grasp. The remainder of the devi- ces makes use of a mechanical solution without cables or cords. Figure 4. Slightly more than half of all the prostheses are body powered from which slightly more than half of the devices are controlled by the wrist. Figure 5. More than half of the actuated hands have an equal force between the fingers. Slightly more than a third of the hands have fingers with independ- ent force due to a separate motor for each finger. Only a small number of the hands have a mechanical linkage system to distribute the force along the fingers. Table 2. Weight of the 3D-printed hand prostheses. Only 11 of the 58 3D-printed upper limb prostheses specified their weights. Weight (g) Andrianesis’ hand [1] 350 Gretsch’ hand [4] 240a Groenewegen’s hand [5] 71b O’Neill’s hand [6] 960 Cyborg beast [21] 131.5 Dextrus EMG [23] 450 Handiii COYOTE [34] 750 InMoov 2 hand [36] 450b Latest bionic arm [40] 250
  • 46. Roboarm [54] 2000 Tact [59] 350b aEstimated weight by the developers. bExcluding connector or socket to fit a human arm. 304 J. T. KATE ET AL. Nine hands use mechanical linkages controlled by motors, and one hand uses compressed air to close the fingers.[44] Type of extensor Figure 7 shows the different solutions that are used to open the hand. A large number (36) of prostheses use elasticity to open the hand automatically. This is achieved through the use of elastic cords (21) and elastic bands (4), and a large number of devices use the elasticity of the finger joints (11) to open the hand. The elastic finger joints are called compliant mechanisms. Hands with these compliant mechanisms consist of fingers that are made from one piece where the phalanges are rigid and the joints are flexible. The remainder of the prostheses have cables or cords (11) or mechanical linkages (8), which are, in both, cases attached to motors. Kinematic specifications The kinematic specifications of each prosthesis are shown in Table 3. The table shows how many joints and degrees of free- dom (DOF) a hand has, how many actuators it has, the range of motion of the different joints and the different grasp types a hand can perform. Most of the information in these tables has
  • 47. been estimated based on published images and videos, as it was not mentioned in the publications. For some hands, basic informa- tion related to the number of actuators or the DOF was specified. Only Andrianesis [1] and Bahari [2] described their hand in more detail and specified the numbers; the remaining hands lack infor- mation related to the kinematic specifications, e.g., DOF�s, ROM and possible grasp type. Number of joints, DOF and actuators All the active hands are underactuated, which means that they have more DOF’s than actuators. This is due to the coupling of the phalanges in the fingers. Most of the fingers of the body- powered prostheses consist of three phalanges that are connected to each other with cables, cords and so on. The cables from all the separate fingers are then attached to one linkage, which ensures that the fingers all move at the same time. For externally powered prostheses, the phalanges are connected to each other with cables or mechanical linkages and are directly connected to motors. The motors control the fingers separately. Range of motion Each finger of a human hand has four joints. The carpometacarpal (CMC) joint, the metacarpo phalangeal (MCP) joint, the proximal interphalangeal (PIP) joint and the distal interphalangeal (DIP) joint.[68] The thumb of a human hand only has three joints. It has
  • 48. no DIP joint, and instead of a PIP joint, it has an interphalangeal (IP) joint, which is described in the table as thumb flexion. The CMC joint of the thumb is also known as the trapeziometacarpal (TMC) joint. This joint is described in the table as thumb circum- duction. None of the 3D-printed hands found have a CMC joint. Except for passive hands, all the hands have an MCP joint and a PIP joint. Only 31 of the 56 active hands have an active DIP joint. Grasp type An adaptive grip is the ability of the fingers to conform to the shape of an object held within the hand. In this case, the force is distributed between the fingers, which ensures that some fingers can still apply a force when the others fingers are halted by an object. This can be performed by 24 of the prostheses, of which 18 can do this by controlling the fingers separately by controlling the motors independently. The hand that is actuated with air pressure can perform an adaptive grip by controlling the pressure in the separate fingers with the use of valves. Only five prostheses have a smart mechanism that distributes the force over all of the fingers. The power grip and precision grip are the two basic grasps a human uses.[69] In addition to these basic grasps, there are four other common types of grasps that are used to perform activities of daily living (ADLs). These four types are the hook grip, spherical grip, tripod grip and lateral grip.[70] All the active hands (56) can perform a power grip, and the majority (54) can also perform a
  • 49. lateral grip. The precision grip can only be performed by 24 of the hands. Almost one-quarter (14) of the hands can perform all six grasp types, which are, in most cases, electrically powered hands with an adaptive grip. 3D-printing technology used to print the upper limb prostheses 3D-printing technique The information related to the 3D-printing technology used to print the prostheses is shown in Table 4. The various techni- ques that are used to print the prostheses are shown in Figure 8. Most of the devices (46) are printed using fused deposition modelling (FDM) technology. The remaining prosthe- ses are made using selective laser sintering (SLS) technology (6), selective stereolithography apparatus (SLA) technology (1), and polyjet printing (1), but in the case of four prostheses, the printing technique is unknown. FDM is the only technique that uses a continues filament to print the part. The other techni- ques make use of a powder or liquid bonded together with the use of a UV laser or UV light. 3D-printing material There is a large variety of materials that can be used for 3D- print- ing. Acrylonitrile butadiene styrene (ABS) and polylactic acid (PLA) are the most commonly used materials to print the prostheses. Figure 6. The type of flexor used to close the prosthesis. The majority of the hands use cables or cords to close the hand. The remainder of the hands use mechanical linkages and one uses compressed air. Figure 7. The type of extensor used to open the prosthesis.
  • 50. Almost two-thirds of the hands use elasticity in the form of elastic cords or bands or compliant mech- anisms to open the hand automatically. 3D-PRINTED UPPER LIMB PROSTHESES: A REVIEW 305 Ta b le 3. Ki n em at ic sp ec ifi ca ti on s of th e 3D -p ri
  • 127. These are the most common materials used for printing with FDM, which is the most commonly used technique to print the devices. The prostheses that are made from flexible materials and FDM 3D-printing make use of NinjaFlex or Filaflex. The chemical name for NinjaFlex is thermoplastic polyurethane.[71] Filaflex is a thermoplastic elastomer with a polyurethane base and some addi- tives.[72] Both these materials stay flexible after first being heated and then cooled down. The prostheses made using SLS 3D- print- ing are made from nylon. SLS 3D-printing most commonly uses standard nylon 11 or nylon 12. The prosthesis made using SLA 3D-printing is made of acrylic plastic, and the prosthesis made using polyjet 3D-printing is made from FullCure 720, which is a photopolymer resin. The Tenim Hand is the only prosthesis that consists of a non-plastic material. This device is made in multiple steps; first, a part from polystyrene is 3D-printed and is then cov- ered with a ceramic layer. The polystyrene is then melted away leaving a cavity in the ceramic that is filled with nylon. This pro- duction method is known as the lost wax casting. Therefore, this prosthesis was made using 3D-printing only as a step in the pro- duction process. Production cost The cost of 20 prostheses is specified and ranges from $5 to $500. The prosthesis that is specified with the lowest cost of $5 only states the cost of the material that is used for the 3D-print-
  • 128. ing. The prosthesis that has the greatest specified cost of $500 states the cost of all the materials that are needed to manufacture the entire hand (e.g., cables, motors, electronics). There are no prostheses that can be bought off-the-shelf; however, there are some companies working on prostheses that could be sold for $1000; for example, You Bionic and Open Bionics are developing a prosthesis that they would like to sell for $3000. Design availability The designs of 31 of the 58 different printed prostheses are avail- able online. Most of the designs can be found on www.thingi- verse.com or www.instructables.com. People can download the CAD-model, print the model and, if necessary, modify the model. Discussion A prosthesis should meet the basic user demands to increase the usability of the prosthesis; these demands can be summarized as cosmesis, comfort, control and function.[73] A prosthesis should be beautiful to look at, comfortable to wear, easy to operate and should have a functional use. A limitation of this study was that a great deal of information on the state of the art 3D-printed upper limb prostheses was found on public websites that are not peer- reviewed. However, we believe, in general, the obtained values appear to be in line with values from the literature. Cosmesis of hand prostheses After functional factors, the appearance is one of the most
  • 129. import- ant factors in prosthesis rejection.[74] To ensure that a prosthesis has an appealing look, the term anthropomorphic is used in the field of prosthetics. This term refers to the capability of a device to mimic the general aspects of the human hand, such as shape, size, colour, temperature and aesthetic factors.[75] All the 3D- printed prostheses are designed to resemble the shape of a human hand, except some hands have a thumb that is positioned at 90� or even at 155� with respect to the fingers. The average size of a human hand has a length of 180–198 mm and a width of 75–90 mm.[76]Ta b le 3. C on ti n ue d Ra n g e of
  • 145. el ec tr ic al ; H ,T ,S : h oo k, tr ip od , sp h er ic al . 3D-PRINTED UPPER LIMB PROSTHESES: A REVIEW 307 http://www.thingiverse.com http://www.thingiverse.com http://www.instructables.com Only the prosthesis developed by Andrianesis specifies the exact dimensions of the prosthesis. The length of this hand is 174 mm and the width is 72 mm. This is slightly smaller than the size of
  • 146. an average human hand. The rest of the hands described in the litera- ture and found on internet do not mention the size. They only mention that the size of the hand can be scaled to match the sound limb. However, this is not possible for hands that are con- trolled by the wrist. These prostheses are fitted to the residual limb, which results in a bigger hand than the sound hand. The majority of the hands have a brightly coloured appearance. Whereas adults appreciate more skin-coloured prostheses,[77] chil- dren may appreciate a coloured appearance.[78] The prostheses developed for adults primarily have a skin colour appearance. Most of the existing conventional prostheses are covered with a cos- metic glove that has a skin-coloured look. Currently, two types of cosmetic gloves are available: a polyvinylchloride (PVC) glove and a silicone glove.[79] The main function of a cosmetic glove is to cover the mechanism and provide the prosthesis with a natural appear- ance. In addition to this main function, the glove also protects the mechanism against moisture and dirt. A negative effect of a Table 4. Print specifications of the 3D-printed hand prostheses. The first part of the table shows the 3D-printed upper limb prostheses found in scientific literature and the second part of the table shows the devices found with the internet search. Fabrication method Material Material cost ($) Design availability
  • 147. Prostheses found in scientific literature Andrianesis’ hand [1], Figure 2(a) SLS Duraform HST – No Bahari’s hand [2] SLA Acrylic plastic – No Gosselin’s hand [3], Figure 2(b) FDM ABS – No Gretsch’ hand [4] FDM ABS 300 No Groenewegen’s hand [5] SLS Nylon – No O’Neill’s hand [6] FDM ABS 500 No Simone’s hand [7] Polyjet Full Cure 720 – No Prostheses found with the internet search 3D-printed prosthesis ecuador [16] FDM – 270 No Adjustable thumb [17] FDM ABS – No Biohand [18] FDM – ±300 No Bionico hand [19] FDM ABS 250 Yes Cyborg arm [20] FDM ABS – No Cyborg beast [21], Figure 2(c) FDM ABS 50 Yes Cyborg beast with I.W.M. [22] FDM ABS – No Dextrus EMG [23] FDM PLA or ABS ±1000 Yes DIY prosthetic hand & forearm [24] FDM – – Yes Falcon hand V1 [25] FDM ABS – Yes Falcon hand V2 [26] FDM ABS – Yes Flexy arm [27] FDM FLA & Filaflex – Yes Flexy hand [28] FDM FLA & Filaflex – Yes Flexy hand 2 [29] FDM FLA & Filaflex – Yes Flexy hand – Filaflex remix [30] FDM Filaflex – Yes GalileoHand [31] FDM PLA or ABS – Yes HACKberry [32] FDM – 200 Yes Handiii [33] Unknown – 300 No Handiii COYOTE [34], Figure 2(d) Unknown – 300 No Hollies hand [35] SLS Nylon – Yes InMoov 2 hand [36] FDM – – Yes IVIANA 2.0 [37], Figure 2(e) Unknown – – No JD-1 [38] FDM Nylon – No K-1 [39] FDM – – No Latest bionic arm [40] FDM – ±3000 No
  • 148. Limbitless arm [41] FDM ABS & Ninjaflex 350 Yes Manu print (Re hand) [42] FDM – 20 No Mind controlled robotic hand [43] FDM ABS 500 Yes Muscle robot hand [44] FDM PLA & Silicone – Yes Not impossible [45] FDM – 100 No Nu hand [46] FDM – – No Odysseus hand [47] FDM ABS – Yes One-hinged Cyborg beast [48] FDM ABS – Yes Prosthetic/robotic hand [49] FDM PLA 1 Yes Pr�otesis Cosm�etica [50] Unknown – – No Raptor hand [51] FDM PLA – Yes Raptor reloaded [52] FDM PLA – Yes RIT arm [53] FDM – – Yes Roboarm [54] FDM PLA 350 Yes Robohand [55] FDM ABS 500 Yes Robot hand [56] FDM ABS & flexible plastic – Yes Scand [57], Figure 2(f) SLS DM_9795 & DM_9770 – No Snap-together Robohand [58] FDM PLA – Yes Tact [59] FDM – 250 Yes Talon flextensor 1.0 [60] FDM ABS – Yes Talon hand 2.0 [61] FDM ABS – Yes Tenim hand [62] SLS Nylon with ceramic layer – No The lucky paw prosthetic hand [63] FDM – – Yes Victory hand [64] FDM – 100 No Youbionic [65] SLS Nylon ±1000 No Zero point frontiers [66] FDM PLA 5 No 308 J. T. KATE ET AL. cosmetic glove is that it results in a greater operational force due to the stiffness of the material. As an extra part for a prosthesis, the glove results in extra costs. None of the 3D-printed hands used
  • 149. a standard glove to cover the mechanism. They are not designed in such a way that a cosmetic glove can cover the mechanism. Only the hand developed by Andrianesis uses a custom fabricated sili- cone glove. As stated previously, the majority of the hands have a colour that does not look like human skin. These prostheses can also be printed using a filament that has a skin colour to give them a skin-like appearance. The Flexy Hand 2 and the Flexy Hand- Filaflex remix are both made using a skin-coloured filament. Protecting the mechanism from moisture and dirt is one of the advantages of a glove. The disadvantages of a glove are the greater operation force required and the additional cost.[79] Printing a prosthesis with skin-coloured appearance results no greater oper- ational force needed and no extra cost required to cover the mech- anism to give the hand a natural appearance. More than one third of the hands are electrically powered in most cases with a servo motor. This results in a noise that can be an undesired aspect of electrically powered hands. Although all prostheses were designed in the shape of a human hand and the majority of the hands can be scaled to the size of the sound hand, most of them still have a non-anthropomorphic look. The appearance of most of the hands is not similar to the appearance of the sound hand. The majority of the hands look more like a mechanical hand than a cosmetic hand,
  • 150. which might result in a greater prosthesis rejection rate. Comfort of hand prostheses A comfortable prosthesis has a good fit and weight that satisfies the user. Almost half of the hands are fitted to the residual limb and tightened using Velcro. The remaining hands can be con- nected to an existing socket. In the Internet and literature search, the prostheses were found to be easily fitted on the residual limb or connected to an existing socket. No information is published on tests or research that has measured the comfort of these pros- theses, and current evidence is mainly anecdotal. The human hand has an average weight of 400 ± 90 g [80] (distal to the wrist and not including the forearm extrinsic muscles). Excessive weight is one of the most important causes of prostheses rejection.[81] Therefore, it is important to provide the weight specifications of the hand prostheses. For 11 devices, the weight of the hand and part of the arm is specified. For four devices, the weight of only the hand is specified: � Groenewegen’s hand: 71 g � Dextrus EMG: 450 g � InMoov 2 hand: 450 g � Tact: 350 g Groenewegen’s hand is extremely light. All the parts for this hand are printed using SLS 3D-printing and are optimized for weight reduction. The other three hands have a comparable weight as the human hand. Comparing the weight of the other seven prostheses shows that six of the prostheses have a similar weight or even a lower weight as similar human arm parts. Only
  • 151. the Cyborg beast has a greater weight than the human body part it replaces. The Cyborg beast is a partial hand prosthesis that replaces the fingers but consists of fingers, a support mechanism and a support to be mounted onto the human hand. The weight of the other partial hand prostheses will probably be greater than the human body part it replaces as well because they are designed in the same way as the Cyborg beast. Although the prostheses that specify a weight have a comparable or slightly lower weight as the human body part it replaces, they are still heavier than some of the commercial available body powered prosthesis.[82] Additionally, it is preferred to have prosthesis that is considerably lighter than 400 ± 90 g.[83] This preferred weight is highly related to the length of the stump. For partial hand pros- theses, the weights are greater than the human body part it repla- ces. To increase the comfort of 3D-printed upper lump prosthesis, it is important that specifications related to weight and fitting of future prostheses are provided. Hand prostheses control Almost 64% of the hands (37) are developed for people with an amputation level below elbow and 31% of the hands (18) are developed for people with a partial hand amputation level. The remaining hands (3) are developed for people with an amputation level above the elbow. This is remarkable as we compare it to numbers for amputation levels in the USA.[84] The literature shows that approximately 25% have an above elbow amputation level, whereas only three 3D-printed hand prostheses have been developed for this purpose. For partial hand amputation, the lit-
  • 152. erature indicates that these procedures are less than 10%, whereas 31% of the 3D-printed hand prostheses are developed for a partial hand amputation level. The exact numbers for the percentages of passive, body-powered and externally powered prosthesis users are unknown.[81] In general, still a remarkable number of people use a passive cosmetic prosthesis,[85] whereas only two of the 58 3D-printed hand prostheses are passive pros- theses. With respect to the type of actuation for the 3D-printed upper limb prostheses, three of the prostheses are passive, 32 of the prostheses are body-powered and 23 are externally powered. Therefore, the focus of 3D-printed upper limb prostheses is more on body-powered and externally powered than on passive pros- theses. Almost 30% of the hands (17) have been developed for people with partial hand loss. These prostheses are body powered and can only be controlled by the wrist. The prostheses devel- oped for all other levels of amputation have a large variety in their type of actuation and type of control. Hand prostheses function The total active range of motion of a human finger is 260�, which is the sum of active flexion at the MCP joint (85�), the PIP joint (110�) and the DIP joint (65�).[68] A little more than one- third of the hands (20) have this range of motion as well. The range of motion of the thumb is very important when performing precision grasp. The thumb circumduction ensures this grasp. Less than half of the hands (20) enable active thumb circumduction. More than a third of the hands (24) can perform adaptive grasp. Only five
  • 153. of the hands have a smart mechanism to enable adaptive grasp. The remainder of the hands, which can perform an adaptive grasp, does this by controlling each finger independently with a Figure 8. The various fabrication methods used to print the prostheses. The majority of the devices are made using FDM technology 3D-PRINTED UPPER LIMB PROSTHESES: A REVIEW 309 separate motor. Using a smart mechanism instead of using mul- tiple motors can lead to significant weight reduction.[86] Although the power grip and precision grip are the most import- ant types of grip in daily life, only 24 of the hands can perform these two types of grip. However, almost all the hands can per- form a power grip and a lateral grip. Future hands should focus more on the most important grasp types used in daily live. This can increase the amount of ADLs a person can perform. The most important aspect of a hand is the ability to perform a secure grip, which is a combination of a grasp type and an applied force. It is only possible to predict the usability of a hand related to tasks if the forces of the hand are specified. Whereas the forces are very important, the forces are only specified from one hand. The Andrianesis’ hand can provide fingertip forces of 3.9–11.5 N and has a maximum grip load of 1.5 kg. The fingertip force of a human hand is 30 N.[87] Although the fingertip forces of the Andrianesis’ hand are relatively low compared with a human hand, it is still sufficient for most ADLs.[68] There are no
  • 154. specifications provided, such as the actuation force, maximum grip force or maximum load, for the remainder of the hands. Future upper limb prostheses should be tested, and the results should be provided to inform people about the specifications of a hand and to compare the new hand to current hands.[82] Future research should be more focused on providing the specifications of 3D-printed hand prostheses, e.g., the actuation force, maximal grip force, weight, battery life and durability, to allow for better selection between the hands. 3D-printing technology used to print the upper limb prostheses Every 3D-printing technique has it benefits and drawbacks. These are related to the accuracy of the printing process, possibility of printing different materials and the cost of printing. 3D-printing technique The majority of the hands (46) are made using the FDM 3D- print- ing technique. This technique is the primary technique used worldwide because it uses a relatively cheap printer and is an easy process. A variety of materials can be used, and in most cases, post processing is not required. The downside of FDM is the fact that very small details are difficult to make. FDM has the greatest layer height of all techniques used to print all prostheses, namely approximately 0.15 mm, which results in a rough surface. If overhanging structures need to be made, FDM printing requires support material, which then has to be subsequently removed. SLS is a technique that uses a much more expensive printer but
  • 155. provides a designer with more freedom with respect to shape. A printed part is build up layer by layer by melting powder using a UV laser. The non-melted powder acts as a support material for overhanging structures. The prostheses that are made using SLS printing have a more free form shape compared with the hands that are printed with the use of FDM printing. Smaller details can be printed using SLS compared with FDM because SLS has a lower minimal layer height, namely approximately 100 lm, result- ing in a smoother surface compared with FDM. SLS printing does not necessarily require post-processing but results in a slightly rough surface. This can be smoothened by polishing or adding a coating. Both SLA and Polyjet printing have the advantage of more design freedom and can print very small details. Both have a very small minimal layer height of approximately 16 lm. The downside of these techniques is that they both need post processing to remove support material, and the material can degrade over time as the photopolymers degrade due to exposure to sunlight.[88] The prostheses made with FDM printing can be printed using a low cost home 3D-printer with a typical cost of approximately $2000. Prostheses made with SLS, SLA and Polyjet printing are printed using a more expensive industrial printer, especially the SLS and Polyjet printers. SLA printers cost approximately $5000, whereas the cost of SLS and Polyjet printers can range from $50,000 to $100,000. Most of the hands do not require small details, which makes FDM printing a suitable technique. Cheap and simple prostheses