3. RUBELLA
Known as German measles
Derived from the Latin, meaning little
red.
This disease is often mild and attacks
often pass unnoticed
Discovered in 18th century - thought to
be variant of measles
4. PATHOGEN
Toga virus
RNA virus
Rapidly inactivated
by chemical agents,
ultraviolet light, low
pH, and heat
6. PATHOGENESIS
Respiratory transmission of virus
Replication in nasopharynx and regional
lymph nodes
Viremia 5-7 days after exposure with
spread to tissues
Placenta and fetus infected during
viremia
7. CLINICAL MANIFESTATIONS
Low grade fever
Swollen glands (post cervical
lymphadenopathy)
Fever rarely rises above 38 oC (100.4 oF).
Joint pains, Headache & conjunctivitis.
Appearance of a rash on the face which
spreads to the trunk and limbs and usually
fades after three days.
8.
9. CONGENITAL RUBELLA SYNDROME
Rubella can cause (CRS)
Intrauterine infection by Rubella virus Leads to
defects;
cardiac
Cerebral
Ophthalmic
auditory defects.
Prematurity
low birth weight
neonatal thrombocytopenia
Anaemia
10. CONT…
Cataracts
Microcephaly
Mental retardation
Bone alterations
Spleen damage
hepatitis.
The skin manifestations are called blueberry
muffin lesions.
The risk of defects is highest for infection in
the first trimester. (miscarriage or a still born
baby)
13. DIAGNOSIS
Isolation of rubella virus from clinical
specimen (e.g., nasopharynx, urine)
Positive serologic test for rubella IgM
antibody
Significant rise in rubella IgG by any
standard serologic assay (e.g., enzyme
immunoassay)
14. TREATMENT
No tx
self-limiting and often asymptomatic
infection
Tx of newly born babies is focused on
management of the complications.
Bed rest
Fluids
Fever reduction
17. Droplet precautions
No specific treatment or antiviral treatment
Keep patient’s skin clean and dry
Isolate precaution until 5 days after rash
disappear
Bed rest and take acetaminophen or another
non-aspirin pain reliever to bring down the
fever.
Ensure pt receive care from non pregnant
caregivers
18.
19.
20. Vaccination
Isolation precautions
Exclusion from school at least 7-10
days
Avoid sharing of articles
Avoid contact
Wash hands
Disinfect surfaces
Wash articles, linen of patients
separately
Keep utensils of patient separate