Rome began as a small settlement along the Tiber River in 753 BC and grew to become one of the largest and most powerful empires in history. Its strategic location in central Italy along major trade routes and defensible position on seven hills contributed to its rise. As the Roman Republic expanded throughout the Mediterranean world from the 4th century BC onward, it developed an extensive network of roads and waterways. Notable monuments like the Colosseum and Pantheon showcased Rome's architectural achievements and cultural dominance during its peak.