Telomeres are repetitive DNA sequences at the ends of chromosomes that prevent shortening as cells divide. Their length declines with age, potentially contributing to aging. Telomerase is an enzyme that adds telomere sequences, counteracting shortening. Studies link both short telomeres and high telomerase to cancer by affecting cell division limits. Researchers are exploring using telomerase to potentially prevent aging, but it may also promote immortality in cancer cells, so more study is needed to safely apply these findings.
Dr Una L Fairbrother
Telomere length: a 21st century biomarker" discusses DNA structure and the nature of telomeres. This talk explains the importance of telomere length and the impact of this feature on human health. The talk finishes describing the exciting work being carried out in London Metropolitan University to help develop this measure as a 21st century biomarker.
Dr Una L Fairbrother
Telomere length: a 21st century biomarker" discusses DNA structure and the nature of telomeres. This talk explains the importance of telomere length and the impact of this feature on human health. The talk finishes describing the exciting work being carried out in London Metropolitan University to help develop this measure as a 21st century biomarker.
Learning and understanding the correlation between telomere shortening and disease is the most important principal to stop the aging process. Dr Sears is one of the worlds most respected and renown Anti-Aging physicians in the world. Please visit our website at www.alsearsmd.com or www.searwellnesscenter.com for tons of great free information.
Telomerase Inhibition as Novel Cancer Therapeutic MethodVincensanicko
Telomere in cancerous cells is conserved even after several rounds of cell division. By identifying the responsible protein in this process, i.e. telomerase, researchers have utilised it as a novel target for cancer treatment. So, how is the telomerase targetted? Are you ready to discover the truth?
TA Sciences presents their latest product TA-65. To learn more about TA-65, check out their website at http://www.tasciences.com TA-65 can help your immune system, vision, male sexual performance, skin appearance and more!
Telomere, Functions & Role in Aging & CancerZohaib HUSSAIN
Why senescence occurs in eukaryotic organisms?
The major function of telomere is to cap the ends of chromosomes and protect the chromosomes from RED mechanism. As cells divide, telomeres continuously shorten with each successive cell division. Telomerase provides the necessary enzymatic activity to restore and maintain the telomere length. The vast majority of tumour's activate telomerase , and only few maintain telomeres by ALT mechanism relying on recombination. Telomere and telomerase are the attractive targets for anti-cancer therapeutics
Learning and understanding the correlation between telomere shortening and disease is the most important principal to stop the aging process. Dr Sears is one of the worlds most respected and renown Anti-Aging physicians in the world. Please visit our website at www.alsearsmd.com or www.searwellnesscenter.com for tons of great free information.
Telomerase Inhibition as Novel Cancer Therapeutic MethodVincensanicko
Telomere in cancerous cells is conserved even after several rounds of cell division. By identifying the responsible protein in this process, i.e. telomerase, researchers have utilised it as a novel target for cancer treatment. So, how is the telomerase targetted? Are you ready to discover the truth?
TA Sciences presents their latest product TA-65. To learn more about TA-65, check out their website at http://www.tasciences.com TA-65 can help your immune system, vision, male sexual performance, skin appearance and more!
Telomere, Functions & Role in Aging & CancerZohaib HUSSAIN
Why senescence occurs in eukaryotic organisms?
The major function of telomere is to cap the ends of chromosomes and protect the chromosomes from RED mechanism. As cells divide, telomeres continuously shorten with each successive cell division. Telomerase provides the necessary enzymatic activity to restore and maintain the telomere length. The vast majority of tumour's activate telomerase , and only few maintain telomeres by ALT mechanism relying on recombination. Telomere and telomerase are the attractive targets for anti-cancer therapeutics
In this way, you can take care of your health and learn more about telomeres. Consider telomere testing and talk to medical experts who focus on telomere research. By working together, we can unlock the mysteries of aging and create a world where healthy longevity is the norm.
Dr. Al Sears explains the Nobel Prize winning breakthrough telomere technology. This opened the way for Harvard researcher, Dr. Ronal DePinho to find a way to activate telomerase. Telomerase is the enzyme that signals your telomeres to grow longer, unfortunately, it shuts down while you are still in your mother's womb.
Once Nobel Prize winning research identified that telomeres are the protective tips at each end of the strands of your DNA, and as your cells replicate, gradully your telomeres grow shorter. They are the "aging-clocks" inside your DNA.
Once Dr. DePinho found a way to reactivate the telomerase enzyme, he turned old mice into young mice again.
Not long after, scientists discovered ways to do this in humans as well, and today, the discovery of the telomere and telomerase are the most important anti-aging breakthrough of our time.
TA-65 is a proven telomerase activator that was discovered by California biotech company Geron Corporation (NDAQ:GERN) and licensed to TA Sciences. Anti-Aging Labs is licensed to sell TA-65 by T.A. Sciences.
TA-65, anti-aging based on Nobel Prize awarded science. For the first time in mankind's age-old quest, something has the potential to extend maximum human lifespan. Reported benefits: significant improvements in immune system, bone density, sexual performance, skin appearance (elasticity), energy levels (endurance), cardiovascular biomarkers and several other areas.
Telomere Diagnostics in the areas of Stem Cells and Male Infertility | Life L...Life Length
Through Life Length’s new series of webinars we want to take Telomere Analysis Technology to clearly defined fields, in order to explore the benefits that telomere measurement can add to your practice.
In this third edition, we will look into the role that telomere analysis plays in the areas of Stem Cells and Male Infertility.
2024.06.01 Introducing a competency framework for languag learning materials ...Sandy Millin
http://sandymillin.wordpress.com/iateflwebinar2024
Published classroom materials form the basis of syllabuses, drive teacher professional development, and have a potentially huge influence on learners, teachers and education systems. All teachers also create their own materials, whether a few sentences on a blackboard, a highly-structured fully-realised online course, or anything in between. Despite this, the knowledge and skills needed to create effective language learning materials are rarely part of teacher training, and are mostly learnt by trial and error.
Knowledge and skills frameworks, generally called competency frameworks, for ELT teachers, trainers and managers have existed for a few years now. However, until I created one for my MA dissertation, there wasn’t one drawing together what we need to know and do to be able to effectively produce language learning materials.
This webinar will introduce you to my framework, highlighting the key competencies I identified from my research. It will also show how anybody involved in language teaching (any language, not just English!), teacher training, managing schools or developing language learning materials can benefit from using the framework.
Palestine last event orientationfvgnh .pptxRaedMohamed3
An EFL lesson about the current events in Palestine. It is intended to be for intermediate students who wish to increase their listening skills through a short lesson in power point.
Read| The latest issue of The Challenger is here! We are thrilled to announce that our school paper has qualified for the NATIONAL SCHOOLS PRESS CONFERENCE (NSPC) 2024. Thank you for your unwavering support and trust. Dive into the stories that made us stand out!
Instructions for Submissions thorugh G- Classroom.pptxJheel Barad
This presentation provides a briefing on how to upload submissions and documents in Google Classroom. It was prepared as part of an orientation for new Sainik School in-service teacher trainees. As a training officer, my goal is to ensure that you are comfortable and proficient with this essential tool for managing assignments and fostering student engagement.
Students, digital devices and success - Andreas Schleicher - 27 May 2024..pptxEduSkills OECD
Andreas Schleicher presents at the OECD webinar ‘Digital devices in schools: detrimental distraction or secret to success?’ on 27 May 2024. The presentation was based on findings from PISA 2022 results and the webinar helped launch the PISA in Focus ‘Managing screen time: How to protect and equip students against distraction’ https://www.oecd-ilibrary.org/education/managing-screen-time_7c225af4-en and the OECD Education Policy Perspective ‘Students, digital devices and success’ can be found here - https://oe.cd/il/5yV
We all have good and bad thoughts from time to time and situation to situation. We are bombarded daily with spiraling thoughts(both negative and positive) creating all-consuming feel , making us difficult to manage with associated suffering. Good thoughts are like our Mob Signal (Positive thought) amidst noise(negative thought) in the atmosphere. Negative thoughts like noise outweigh positive thoughts. These thoughts often create unwanted confusion, trouble, stress and frustration in our mind as well as chaos in our physical world. Negative thoughts are also known as “distorted thinking”.
Ethnobotany and Ethnopharmacology:
Ethnobotany in herbal drug evaluation,
Impact of Ethnobotany in traditional medicine,
New development in herbals,
Bio-prospecting tools for drug discovery,
Role of Ethnopharmacology in drug evaluation,
Reverse Pharmacology.
1. Telomeres And TelomeraseThe Secret To Aging And Cancer Geneticist Richard Cawthon says “One estimate is people could live 1,000 years” By: Rohan Parikh
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3. Telomeres Telomeres main function is by preventing chromosomes from losing base pair sequences at their ends. They also stop chromosomes from fusing to each other. Telomeres are the repeating sequences of DNA Example-(TTAGGG). In human blood cells, each time a cell divides, an average person loses about 115 base pairs from the ends of that cell's telomeres. The length of telomeres is about 8,000 base pairs at birth. As people age they can have as low as 1,500 in elderly people.
4. How Are Telomeres Related To Aging & Cancer Aging- Geneticist Richard Cawthon did an experiment where he divided people in to two groups, one group of people with long telomeres and one group of people with short telomeres. He found that the group with long telomeres lived longer and were healthier than those with shorter telomeres. He concluded that telomeres play a key role in aging and overall health. Cancer-If a cell begins to become cancerous, it divides more often, and its telomeres become very short. If its telomeres get too short, the cell could die. Studies have found shortened telomeres in many cancers, including pancreatic, bone, prostate, bladder, lung, kidney, and head and neck.
5. Telomerase Telomerase (telomere terminal transferase) is an enzyme made of protein and RNA that help chromosomes by adding TTAGGG sequences to the end of existing chromosomes to keep telomeres. Telomerase is found in fetal tissues, adult germ cells and also tumor cells. In young cells, telomerase keeps telomeres from wearing down too much. But as cells divide repeatedly, there is not enough telomerase, so the telomeres grow shorter and the cells age.
6. How Is Telomerase Related Aging and Cancer Aging-As cells divide repeatedly(50-70 times in their lifetime), there is not enough telomerase for all the divisions of the cell. The telomeres grow shorter and the cells age. Scientists have used telomerase to stop cells from aging. Cancer- The whole point of telomerase is to preserve telomeres by keep adding telomeres to the chromosome. And Telomerase has been increased in cancer cells, which means cancer cells are theoretically immortal. Scientists have used telomerase to divide cells far beyond the normal limit and the cells did not become cancerous.
7. Technology Behind Telomeres And Telomerase If telomerase makes cancer cells immortal, it could theoretically prevent normal cells from aging. We (humans) all have the gene to make telomerase, but it’s switched off. Scientists are exploring the possibility of inserting a gene for telomerase into aging cells or developing a drug to turn on the gene for telomerase. There is still research going on how to make the cancer cells stop getting telomerase.
8. In Theory Measuring telomerase may be a new way to detect cancer. If scientists can learn how to stop telomerase, they might be able to fight cancer by making cancer cells age and die. But there are risks. Blocking telomerase could impair fertility, stop healing, and production of blood cells and immune system cells. If telomerase could be used routinely to immortalize human cells, it would be theoretically possible to mass produce any human cell for transplantation.
9. Works Cited Genetic Science Learning Center. "Are Telomeres the Key toAging and Cancer?." Learn.Genetics 5 February 2011<http://learn.genetics.utah.edu/content/begin/traits/telomeres/> . Aten, David. "What are telomeres and telomerase?." Shay/Wright Laboratory. N.p., September 6, 2007. Web. 5 Feb 2011. <http://www4.utsouthwestern.edu/cellbio/shay-wright/index.html>. "Graphic: Telomeres and Telomerase." Web. 5 Feb 2011. <http://www.bing.com/images/search?q=telomeres&view=detail&id=CA081E65DF5545037D3A1A34 968CBE3E0F21677&first=1&FORM=IDFRIR>. "Telomerase." Geron. N.p., n.d. Web. 5 Feb 2011. <http://www.geron.com/technology/telomerase/telomerase.aspx>. "Regulation of telomere length in normal and cancer cells by telomerase." Web. 5 Feb 2011. <http://www.bing.com/images/search?q=telomermase&view=detail&id=5B39D66AE69E6D9E91BE578D843 781371DE3D58&first=1&FRM=IDFRIR>.
