The document discusses peptic ulcers, which are sores in the lining of the stomach or duodenum caused by acid and pepsin attacks. It states that the major cause of peptic ulcers is Helicobacter pylori bacteria, which colonizes the gastric mucous and causes increased acid production through urease activity. H. pylori infection leads to chronic ulceration due to the weakening of the mucosal resistance from its protease enzymes and the resulting acid and pepsin digestion of the mucosa.

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2. Pathology of Peptic Ulcer By ali aziz

3. Normal Stomach

4. Esophagus & Stomach Normal

7. H. Pylori organisms- silver st.

9. Etiology of PUD Normal Increased Attack Hyperacidity Weak defense Helicobacter pylori * Stress, drugs, smoking

13. Acute Esophagitis & Gastritis

14. Gastric peptic ulcer:

15. Gastric peptic ulcer:

16. Gastric Ulcer

17. Duodenal Peptic Ulcer

18. Gastric Ulcer

19. Peptic ulcer - Endoscopy

20. Gastric Ulcer

21. Gastric Ulcer

23. Peptic Ulcer

24. Peptic Ulcer Microscopy:

25. Perforation:

26. Acute Esophagitis & Gastritis

27. Fungating

28. Linitis Plastica – Schirrhous Carcinoma.

32. Helecobacter pylori

33. “ You get ulcer, not from what you eat, but from what’s eating you..!”