RNs role in kidney transplant recipient in the immediate post-operative period; RN\'s role in organ transplantation to assess, plan, implement, practice evidence based approach to evaluate care interventions in the care of the transplant patient . To analyse the biological, psychological and sociological effects of transplantation on the patient. Post-transplant nursing care for the patient begins in the post-anesthesia care unit. The first 24 hours after transplantation represent a critical period, marked by hemodynamic and respiratory instability, and there is a great risk of developing complications, mainly of graft rejection. The nurse treating the patient in the early post-transplant period needs specialized knowledge to reduce the problems, prevent or anticipate and intervene immediately to maximize the result of long-term graft and provide quality care throughout the hospitalization period. The behavior of diuresis is the most important element in the monitoring of renal functions, since it causes therapeutic behaviors such as hydration, medication and even surgery for urologic complications. The urinary catheter placement provides accurate measurement of urine output and determines the presence of hemorrhage and blood clot, acute graft rejection, and vascular thrombosis, and is a predictor of the development of transplantation. The urinary catheter is removed after proper healing of the anastomosis of the ureter into the bladder, when continued monitoring of urine volume is required. During the hospitalization of the patient, daily blood tests must be done, with the most relevant results including levels of serum creatinine, polymerase chain reaction (PCR), white cell count, and levels of immunosuppressive drugs. These parameters determine that the kidney function is effective and show the first signs of a possible rejection or infection, and whether the drug levels are within the therapeutic range required for the maintenance of immunosuppression or induction, maintenance and treatment of rejection. The nurse should moniter the patient\'s hemodynamic status and fluid volume to avoid post- transplant complications while maintaining central venous pressure at 10 mmHg and systolic blood pressure above 120 mmHg. Urine output is replaced on an hourly milliliter-for-milliliter basis and should be recorded hourly. RNs role in kidney transplant donor in the immediate post-operative period Donors face the possibility of post-operative complications such as bleeding, wound infection, fever, etc. Most of the post-operative complications are generally short-term and can be addressed with quality medical care. Closely monitor the renal function to assess for impairment and monitor the hematocrit to asses for bleeding . Donors experience more pain than recipient. Donor who had an open surgical approach may experience more pain than when a laproscopic approach used. Donors who had open approach will be usually discharged from hospital in 4 or 5 day.