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Department of Ophthalmology
                  Russian People’s Friendship University1
                  Moscow, Russian Federation



                  Ophthalmic unit of Skhodnya city hospital 2,
                  Moskovskaya oblast.

Kumar V.1,2, Frolov M.A.1 , Dzumova A.A.2 ,Isufaj E. 1, Bojhok
                            E.V. 1


Results of transciliary filtration (TCF)
 and transconjunctival transciliary
    filtration (TCTCF) in surgical
 management of refractory primary
  open-angle glaucoma (RPOAG).
     Innovative educational program of the University
               Financial disclosure - none
Surgical treatment of refractive glaucoma


Drainage of anterior chamber with the
     use of different implants and
   drainage devices or without them

    Less effective.
   Complication rates during surgery and
    in postoperative periods are
    significantly high.
   As a result in most of the cases the
    eyes are subjected to either
    evisceration or enucleation.
Posterior chamber drainage through ciliary body –

                    transciliary filtration




     Professor Daljit Singh             Professor Takhchidi K.P.
        (Amritsar, india)                      (Russia)
    Manual TCF        – 1979.           Diode laser TCF– 1992г.
    Erbium laser TCF – 1993-2000
     Plasma TCF       – 2001
Fugo plasma blade - new
                 fundamental energy
                   (Nanotechnology in the truest
                             sense )
The tissues are treated at the
molecular and atomic levels,
without causing collateral
damage.
When the tip is activated, it gets
coated with plasma, which is
resonant with the tissues that are
touched.
The  tissue absorbs energy by
resonance, the tissue molecules
become unstable, therefore they                        Video clip
                                           (by Prof. Richard Fugo, USA)
shatter, and they get removed in                          Voice
the form of a plume.                          (Prof. Daljit Singh, India)
Surgical technique of TCF and TCTCF
Purpose
To study effectiveness of TCF and TCTCF
procedures in surgical management of
RPOAG.

                 Setting
Department of ophthalmology,
Russian people’s friendship university,
Moscow
Ophthalmic unit of Skhodnya city hospital,
Moscovskaya oblast
Methods and material
    Total 20 cases (20 eyes): male – 10 (50%); female – 10 (50%)
         TCF : 6 cases (30%) and TCTCF : 14 cases (70%)
          Study period: September 2009 - December 2009
     Exclusion criteria: minimum follow – Less than 3 months

•    Cases were admitted for evisceration for painful terminal
     glaucoma
•    Intraocular pressure (IOP) varied from 25 – 45 mmHg (avg. IOP
     was 32.75 +– 4.79 mmHg).
•    All patients were instilling not less than 2 eye drops
Methods and material
     Main outcome measures:
              IOP change,
            complication rate,
     additional glaucoma medication,
        need for surgical revision.

         Criteria for success:
              relief from pain,
       normal outlook of the eye ball,
decrease in preoperative IOP by 30% or more
    with or without glaucoma medication.
Results
Observations during surgery:

TCF and TCTCF procedures
were technically easy to
perform.
PC drainage was achieved in
all cases.
Surgical time ranged between
7 to 10 minutes.
Deepening         of  anterior
chamber in every case.
No case of hemorrhagic
choroidal effusion.
Bleeding from the tunnel – in
3 cases (15%).
Results
    Observations in post-operative period
       (follow-up period – 3 months)                     1st day


                                                        7th day
 Success rate – 65% (13 cases)
   Additional glaucoma medication - 3 cases (15).
 Need for surgical revision – 35% (7 cases)
   Repeat TCF or TCTCF - 4 cases (20%).
   Implantation of stainless steel wire drainage
   device - 2 cases (10%).
   Evisceration of eye ball – 5% (1 case)
Choroidal effusion - 5 cases (25%).
Hyphema – 6 cases (dissolved spontaneously).        OCT after 6 months
Failure reasons
 Blockage  of the outer opening
     fibrosis
     antimetabolites?

 Blockage  of the inner opening
     anterior chamber irrigation
     More trauma ?


 Due to high reactivity and
 elasticity of ciliary body
Conclusions
TCF and TCTCF though is a technically
simple and easy to perform procedure, but in
its present day form failure rate in surgical
management of RPOAG is significantly high.
Modification of this procedure by using
antimetabolites perioperatively may enhance
its success rate.

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Results of tcf and tctcf in surgical management of rpoag 1

  • 1. Department of Ophthalmology Russian People’s Friendship University1 Moscow, Russian Federation Ophthalmic unit of Skhodnya city hospital 2, Moskovskaya oblast. Kumar V.1,2, Frolov M.A.1 , Dzumova A.A.2 ,Isufaj E. 1, Bojhok E.V. 1 Results of transciliary filtration (TCF) and transconjunctival transciliary filtration (TCTCF) in surgical management of refractory primary open-angle glaucoma (RPOAG). Innovative educational program of the University Financial disclosure - none
  • 2. Surgical treatment of refractive glaucoma Drainage of anterior chamber with the use of different implants and drainage devices or without them  Less effective.  Complication rates during surgery and in postoperative periods are significantly high.  As a result in most of the cases the eyes are subjected to either evisceration or enucleation.
  • 3. Posterior chamber drainage through ciliary body – transciliary filtration Professor Daljit Singh  Professor Takhchidi K.P. (Amritsar, india) (Russia) Manual TCF – 1979. Diode laser TCF– 1992г. Erbium laser TCF – 1993-2000 Plasma TCF – 2001
  • 4. Fugo plasma blade - new fundamental energy (Nanotechnology in the truest sense ) The tissues are treated at the molecular and atomic levels, without causing collateral damage. When the tip is activated, it gets coated with plasma, which is resonant with the tissues that are touched. The  tissue absorbs energy by resonance, the tissue molecules become unstable, therefore they Video clip (by Prof. Richard Fugo, USA) shatter, and they get removed in Voice the form of a plume. (Prof. Daljit Singh, India)
  • 5. Surgical technique of TCF and TCTCF
  • 6. Purpose To study effectiveness of TCF and TCTCF procedures in surgical management of RPOAG. Setting Department of ophthalmology, Russian people’s friendship university, Moscow Ophthalmic unit of Skhodnya city hospital, Moscovskaya oblast
  • 7. Methods and material Total 20 cases (20 eyes): male – 10 (50%); female – 10 (50%) TCF : 6 cases (30%) and TCTCF : 14 cases (70%) Study period: September 2009 - December 2009 Exclusion criteria: minimum follow – Less than 3 months • Cases were admitted for evisceration for painful terminal glaucoma • Intraocular pressure (IOP) varied from 25 – 45 mmHg (avg. IOP was 32.75 +– 4.79 mmHg). • All patients were instilling not less than 2 eye drops
  • 8. Methods and material Main outcome measures: IOP change, complication rate, additional glaucoma medication, need for surgical revision. Criteria for success: relief from pain, normal outlook of the eye ball, decrease in preoperative IOP by 30% or more with or without glaucoma medication.
  • 9. Results Observations during surgery: TCF and TCTCF procedures were technically easy to perform. PC drainage was achieved in all cases. Surgical time ranged between 7 to 10 minutes. Deepening of anterior chamber in every case. No case of hemorrhagic choroidal effusion. Bleeding from the tunnel – in 3 cases (15%).
  • 10. Results Observations in post-operative period (follow-up period – 3 months) 1st day 7th day  Success rate – 65% (13 cases) Additional glaucoma medication - 3 cases (15).  Need for surgical revision – 35% (7 cases) Repeat TCF or TCTCF - 4 cases (20%). Implantation of stainless steel wire drainage device - 2 cases (10%). Evisceration of eye ball – 5% (1 case) Choroidal effusion - 5 cases (25%). Hyphema – 6 cases (dissolved spontaneously). OCT after 6 months
  • 11. Failure reasons  Blockage of the outer opening fibrosis antimetabolites?  Blockage of the inner opening anterior chamber irrigation More trauma ?  Due to high reactivity and elasticity of ciliary body
  • 12. Conclusions TCF and TCTCF though is a technically simple and easy to perform procedure, but in its present day form failure rate in surgical management of RPOAG is significantly high. Modification of this procedure by using antimetabolites perioperatively may enhance its success rate.