· Response Guidelines Reply to the posts of two peers in this discussion. You may want to share insights you have related to your peer's application of research concepts, or ask a clarifying question. You may choose to comment on how the article presented by your peer is relevant to your own professional interests. Each peer response need to have at least two references. 1 st Peer posting Chang et al. (2016) conducted a study to determine if there was an answer to the contradicting study results regarding the brain activity in schizophrenics and their siblings. Earlier research has given mixed results stating that schizophrenics have excessive brain activity and others show that they have incoherent activity. The same mixed results showed up in research on siblings of schizophrenics. This study used amplitudes of low-frequency fluctuations (ALFF) as well as regional homogeneity (Reho). The used the ALFF and Reho to track the intensity as well as any synchronization of local spontaneous neuronal activity among three groups of participants (Chang et al., 2016). Repovs and Barch (2012) conducted a study using a similar research design but instead they were looking for how functional connectivity may differ in schizophrenics when there is no cognitive task involved, a light cognitive task, and then a more demanding cognitive task. The study used participants who were diagnosed with schizophrenia and their siblings, and health individuals and their siblings. These four different groups helped to determine if there was any difference between a sibling of an individual with schizophrenia compared to siblings that were not impaired. The study focused on the working memory of the individuals. fMRI scans were used as well as other basic imaging and recall memory assessment activities (Repovs & Barch, 2012). The study conducted by Chang et al. (2016) was using reliable testing techniques in regards to the neuronal activity that was tracked. The sample size was not very large but did have the randomized factor by comparing the results to not one but two variables (siblings and non-related healthy individuals). Had the sample size been larger the results could likely be more generalizable. The participants were gathered using participants from a other studies the researchers had done. There were 27 participants who were diagnosed with schizophrenia, 27 non effected siblings, and 27 healthy unrelated participants. The research design was used to map the activity in the brain of all three groups in different circumstances so they could compare the results to find any commonalities or clear differences. This method of research helped to determine if there was any validity to the claims of either excessive brain activity or incoherent activity in schizophrenics and their siblings. This study seems to be a quasi-experimental study since it has a group used for comparison but it does not use random assignment (Sherperis, Young & .