The 16-year-old male patient was admitted to the hospital with a frontal traumatic brain injury caused by being hit with a baseball bat. On admission, he had a Glasgow Coma Scale of 12, was confused and had left-sided weakness. A CT scan revealed a right frontal epidural hematoma, which was evacuated during craniotomy surgery. The patient also received the first treatment cycle of Renacenz. After 24 hours, his GCS improved to 15 and he was regaining mobility in his left side. By the end of the Renacenz treatment, the patient had made a full recovery without neurological impairments.