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CURRICULUM VITAE
                                               Jack R. Reifert

CONTACT INFORMATION

Address:       2528 Orella St. Unit-B                      Email:       reifert@lifesci.ucsb.edu
               Santa Barbara, CA 93150                     Phone:       (858) 922-5923

EDUCATION

2005-2011      Doctor of Philosophy (Ph.D.) : Molecular, Cellular, and Developmental Biology (MCDB)
               University of California, Santa Barbara

1996-2000      Bachelor of Science (B.S.) : Pharmacological Chemistry
               University of California, San Diego

RESEARCH EXPERIENCE

2011-Present   Postdoctoral Fellow (CIRM), Chemical Engineering, University of California, Santa Barbara
                    Advisor: Professor Patrick Daugherty, Ph.D.

               Current Project: Discovery and engineering of peptide inhibitors targeting proteases involved in ovarian
               cancer metastasis for use as potential therapeutics and as probes for the detection of cancer stem cells.

2005-2011      Ph.D., MCDB / Neuroscience Research Institute (NRI), University of California, Santa Barbara
                     Advisor: Professor Stuart Feinstein, Ph.D.

               Thesis Topic: Mechanisms of amyloid beta induced neuronal cell death.

               -    Expanded the lab’s in-vitro knowledge of tau biochemistry into neuronal culture experiments,
                    resulting in new mechanistic models of amyloid beta mediated tau dysfunction.

2002-2005      Research Associate, Salmedix Inc. (San Diego, California)
                    Supervisors / Mentors: Dr. Lorenzo Leoni, Ph.D. (cofounder) and Dr. Christina Niemeyer, Ph.D.

               Duties: Researched mechanisms of action, combination potential, and tested second-generation analogs
               of multiple cancer therapeutics in phase II clinical trials.

               -   My work with the biology research group directly influenced Bendamustine (Treanda) clinical trails
                   for B-Cell NHL and helped suggest a mechanism of action divergent from other chemotherapies.

2001-2002      Quality Control Associate I, BD Pharmingen (San Diego, California)
                     Supervisor: Suzanna Synenki

               Duties: Tested antibodies in immunoblotting, ELISA, and flow-cytometry formats for product release.

2000-2001      Research Associate, Sam and Rose Stein Institute for Research on Aging (UC San Diego)
                    Advisor: Dr. Dennis Carson, M.D. (Worked with Dr. Malini Sen, Ph.D.)

               Research Topic: Mechanisms of wnt / β-catenin signaling in the progression of rheumatoid arthritis.

1999-2000      Undergraduate Researcher, Sam and Rose Stein Institute for Research on Aging (UC San Diego)
               (Same as above)




                                                     Page 1 of 2
CURRICULUM VITAE
                                                        Jack R. Reifert

PUBLICATIONS

Reifert J, Hartung-Cranston D, Feinstein S.C. “Tau fragmentation without marked changes in tau phosphorylation precedes
amyloid beta mediated cell death in cultured hippocampal neurons.” J Biol Chem. 286(23): 20797-811. Jun. 2011


Sun CJ, Srivastava A, Reifert JR, Waite JH. “Halogenated DOPA in a marine adhesive protein.” J. Adhesion 85(2-3): 126-138. Feb.
2009

Leoni LM, Bailey B, Reifert J, Bendall HH, Zeller RW, Corbeil J, Elliott G, Neimeyer CC. “Bendamustine (Treanda) displays distinct
pattern of cytotoxicity and unique mechanistic features compared with other alkylating agents.” Clin Cancer Res. 14(1): 309-17. Jan. 2008

Sen M, Reifert J, Lauterbach K, Wolf V, Rubin JS, Corr M, Carson DA. “Regulation of fibronectin and metalloproteinase expression by
Wnt signaling in rheumatoid arthritis synoviocytes.” Arthritis Rheum. 46(11): 2867-77. Nov. 2002

Sen M, Chamorro M, Reifert J, Corr M, Carson DA. “Blockade of Wnt-5A/frizzled 5 signaling inhibits rheumatoid synoviocyte
activation.” Arthritis Rheum. 44(4): 772-81. Apr. 2001


HONORS / AWARDS / SKILL DEVELOPMENT WORKSHOPS

2010                 Nominated and appointed Associate Faculty Member of Faculty of 1000 (F1000)
2010                 Teaching assistant for the Advanced Microscopy Workshop for live-cell imaging techniques at UCSB
2009                 Student in the UCSB Microscopy Workshop learning microscopy systems and fixed cell imaging
2009                 Award for best poster at the annual MCDB retreat
                                                                     th
2008                 Shing and Shang-Yung Chang Award for best 4 year graduate research talk
2005                 Storke Award for highest achievement in first year graduate coursework

CONFERENCES AND MEETINGS
                                      th
2010                 Attended the 40 Society for Neuroscience Annual Meeting, San Diego
                                         th
2009                 Poster Presenter, 49 Meeting for The American Association for Cell Biology (ASCB), San Diego
                                         th
2008                 Poster Presenter, 47 Meeting for The American Association for Cell Biology (ASCB), San Francisco
                                    th
2007                 Attended the 37 Society for Neuroscience Annual Meeting, San Diego
                                                            th
2005                 Poster Presenter, 7 Abstracts at the 96 American Association for Cancer Research (AACR), Anaheim
                                         th
2004                 Poster Presenter, 46 American Association of Hematology (ASH), San Diego
                                                            th
2004                 Poster Presenter, 5 Abstracts at the 95 American Association for Cancer Research (AACR), Orlando
                                                            th
2003                 Poster Presenter, 3 Abstracts at the 94 American Association for Cancer Research (AACR), DC

TEACHING EXPERIENCE

2006-2009            4 Years, Introductory Biology Lab (MCDB 1AL), UC Santa Barbara
2006-2008            3 Years, Developmental Neuroscience (MCDB 115), UC Santa Barbara
2007                 Mentor for an undergraduate student, UC Santa Barbara


REFERENCES AVAILABLE UPON REQUEST




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Jack Reifert's CV

  • 1. CURRICULUM VITAE Jack R. Reifert CONTACT INFORMATION Address: 2528 Orella St. Unit-B Email: reifert@lifesci.ucsb.edu Santa Barbara, CA 93150 Phone: (858) 922-5923 EDUCATION 2005-2011 Doctor of Philosophy (Ph.D.) : Molecular, Cellular, and Developmental Biology (MCDB) University of California, Santa Barbara 1996-2000 Bachelor of Science (B.S.) : Pharmacological Chemistry University of California, San Diego RESEARCH EXPERIENCE 2011-Present Postdoctoral Fellow (CIRM), Chemical Engineering, University of California, Santa Barbara Advisor: Professor Patrick Daugherty, Ph.D. Current Project: Discovery and engineering of peptide inhibitors targeting proteases involved in ovarian cancer metastasis for use as potential therapeutics and as probes for the detection of cancer stem cells. 2005-2011 Ph.D., MCDB / Neuroscience Research Institute (NRI), University of California, Santa Barbara Advisor: Professor Stuart Feinstein, Ph.D. Thesis Topic: Mechanisms of amyloid beta induced neuronal cell death. - Expanded the lab’s in-vitro knowledge of tau biochemistry into neuronal culture experiments, resulting in new mechanistic models of amyloid beta mediated tau dysfunction. 2002-2005 Research Associate, Salmedix Inc. (San Diego, California) Supervisors / Mentors: Dr. Lorenzo Leoni, Ph.D. (cofounder) and Dr. Christina Niemeyer, Ph.D. Duties: Researched mechanisms of action, combination potential, and tested second-generation analogs of multiple cancer therapeutics in phase II clinical trials. - My work with the biology research group directly influenced Bendamustine (Treanda) clinical trails for B-Cell NHL and helped suggest a mechanism of action divergent from other chemotherapies. 2001-2002 Quality Control Associate I, BD Pharmingen (San Diego, California) Supervisor: Suzanna Synenki Duties: Tested antibodies in immunoblotting, ELISA, and flow-cytometry formats for product release. 2000-2001 Research Associate, Sam and Rose Stein Institute for Research on Aging (UC San Diego) Advisor: Dr. Dennis Carson, M.D. (Worked with Dr. Malini Sen, Ph.D.) Research Topic: Mechanisms of wnt / β-catenin signaling in the progression of rheumatoid arthritis. 1999-2000 Undergraduate Researcher, Sam and Rose Stein Institute for Research on Aging (UC San Diego) (Same as above) Page 1 of 2
  • 2. CURRICULUM VITAE Jack R. Reifert PUBLICATIONS Reifert J, Hartung-Cranston D, Feinstein S.C. “Tau fragmentation without marked changes in tau phosphorylation precedes amyloid beta mediated cell death in cultured hippocampal neurons.” J Biol Chem. 286(23): 20797-811. Jun. 2011 Sun CJ, Srivastava A, Reifert JR, Waite JH. “Halogenated DOPA in a marine adhesive protein.” J. Adhesion 85(2-3): 126-138. Feb. 2009 Leoni LM, Bailey B, Reifert J, Bendall HH, Zeller RW, Corbeil J, Elliott G, Neimeyer CC. “Bendamustine (Treanda) displays distinct pattern of cytotoxicity and unique mechanistic features compared with other alkylating agents.” Clin Cancer Res. 14(1): 309-17. Jan. 2008 Sen M, Reifert J, Lauterbach K, Wolf V, Rubin JS, Corr M, Carson DA. “Regulation of fibronectin and metalloproteinase expression by Wnt signaling in rheumatoid arthritis synoviocytes.” Arthritis Rheum. 46(11): 2867-77. Nov. 2002 Sen M, Chamorro M, Reifert J, Corr M, Carson DA. “Blockade of Wnt-5A/frizzled 5 signaling inhibits rheumatoid synoviocyte activation.” Arthritis Rheum. 44(4): 772-81. Apr. 2001 HONORS / AWARDS / SKILL DEVELOPMENT WORKSHOPS 2010 Nominated and appointed Associate Faculty Member of Faculty of 1000 (F1000) 2010 Teaching assistant for the Advanced Microscopy Workshop for live-cell imaging techniques at UCSB 2009 Student in the UCSB Microscopy Workshop learning microscopy systems and fixed cell imaging 2009 Award for best poster at the annual MCDB retreat th 2008 Shing and Shang-Yung Chang Award for best 4 year graduate research talk 2005 Storke Award for highest achievement in first year graduate coursework CONFERENCES AND MEETINGS th 2010 Attended the 40 Society for Neuroscience Annual Meeting, San Diego th 2009 Poster Presenter, 49 Meeting for The American Association for Cell Biology (ASCB), San Diego th 2008 Poster Presenter, 47 Meeting for The American Association for Cell Biology (ASCB), San Francisco th 2007 Attended the 37 Society for Neuroscience Annual Meeting, San Diego th 2005 Poster Presenter, 7 Abstracts at the 96 American Association for Cancer Research (AACR), Anaheim th 2004 Poster Presenter, 46 American Association of Hematology (ASH), San Diego th 2004 Poster Presenter, 5 Abstracts at the 95 American Association for Cancer Research (AACR), Orlando th 2003 Poster Presenter, 3 Abstracts at the 94 American Association for Cancer Research (AACR), DC TEACHING EXPERIENCE 2006-2009 4 Years, Introductory Biology Lab (MCDB 1AL), UC Santa Barbara 2006-2008 3 Years, Developmental Neuroscience (MCDB 115), UC Santa Barbara 2007 Mentor for an undergraduate student, UC Santa Barbara REFERENCES AVAILABLE UPON REQUEST Page 2 of 2