High yield production of therapeutic proteins in chloroplastSHRIKANT YANKANCHI
A biopharmaceutical, also known as a biologic(al) medical product, biological, or biologic, is any pharmaceutical drug product manufactured in, extracted from, or semisynthesized from biological sources- Wikipedia
High yield production of therapeutic proteins in chloroplastSHRIKANT YANKANCHI
A biopharmaceutical, also known as a biologic(al) medical product, biological, or biologic, is any pharmaceutical drug product manufactured in, extracted from, or semisynthesized from biological sources- Wikipedia
It deals with application of such genes and proteins obtained from the animals especially for medicine and also industries. It is much useful to understand the basic.
Biotechnological techniques have been used to produce a number of commercially available products. Despite the ethical issues concerned with this technology, a number of commercial products have been produced.
R protein expression in rice in the recombinant protien which is expressed in rice to overcome all the abiotic factors which is a stress to the rice in some non ecological condition
TRANSGENIC PLANTS AS SOLE SOURCE FOR BIOPHARMACEUTICALSmukund joshi
Proteins with applications for human or animal vaccines and expressed by transgenic plants.
Advantages of transgenic plants as protein expression systems.
Cow´s milk allergy is a common food allergy especially among infants and young children. The major allergen in cow´s milk is beta-lactoglobulin (BLG) and BLG-specific antibodies are needed for diagnostic, therapeutic, food processing and quality verification applications. At VTT we have established a IgE antibody library from a milk allergic person and identified high-affinity antibodies against native and heat denaturated BLG. As an alternative production system, we have used barley as a production host. Proof-of-concept was gained with expressing the BLG-specific antibody in barley cell culture. Best production levels in barley grains were obtained with glutelin-specific promoter combined to ER targeting and retention signals. The barley-produced BLG-specific antibody was successfully purifed with affinity-based chromatography and the functionality of barley-produced BLG-specific antibody was verified by ELISA and immunoprecipitation assays. The developed barley-based expression system clearly demonstrated its potential for application in the processing of dairy milk products as well as in detecting allergens from foods possibly contaminated by cow´s milk.
Future trends and perspectives in modern pharmaceutical biotechnologyinemet
PharmaCon2007 Congress, Dubrovnik, Croatia "New Technologies and Trends in Pharmacy, Pharmaceutical Industry and Education" http://www.pharmacon2007.com
Abstract is available at http://www.pharmaconnectme.com
Global cancer biosimilars market opportunity outlookKuicK Research
"Global Cancer Biosimilars Market Opportunity Outlook" Report Highlight & Findings:
Introduction & Mechanism of Cancer Biosimilars
Global Cancer Biosimilars Market Dynamics
FDA & EMA Guidelines on Development & Marketing of Biosimilars
Cancer Biosimilars Clinical Pipeline by Company, Indication & Phase
Cancer Biosimilars Clinical Pipeline: 100 Biosimilars
Marketed Cancer Biosimilars Clinical Insight
Marketed Cancer Biosimilars: 15 Biosimilars
It deals with application of such genes and proteins obtained from the animals especially for medicine and also industries. It is much useful to understand the basic.
Biotechnological techniques have been used to produce a number of commercially available products. Despite the ethical issues concerned with this technology, a number of commercial products have been produced.
R protein expression in rice in the recombinant protien which is expressed in rice to overcome all the abiotic factors which is a stress to the rice in some non ecological condition
TRANSGENIC PLANTS AS SOLE SOURCE FOR BIOPHARMACEUTICALSmukund joshi
Proteins with applications for human or animal vaccines and expressed by transgenic plants.
Advantages of transgenic plants as protein expression systems.
Cow´s milk allergy is a common food allergy especially among infants and young children. The major allergen in cow´s milk is beta-lactoglobulin (BLG) and BLG-specific antibodies are needed for diagnostic, therapeutic, food processing and quality verification applications. At VTT we have established a IgE antibody library from a milk allergic person and identified high-affinity antibodies against native and heat denaturated BLG. As an alternative production system, we have used barley as a production host. Proof-of-concept was gained with expressing the BLG-specific antibody in barley cell culture. Best production levels in barley grains were obtained with glutelin-specific promoter combined to ER targeting and retention signals. The barley-produced BLG-specific antibody was successfully purifed with affinity-based chromatography and the functionality of barley-produced BLG-specific antibody was verified by ELISA and immunoprecipitation assays. The developed barley-based expression system clearly demonstrated its potential for application in the processing of dairy milk products as well as in detecting allergens from foods possibly contaminated by cow´s milk.
Future trends and perspectives in modern pharmaceutical biotechnologyinemet
PharmaCon2007 Congress, Dubrovnik, Croatia "New Technologies and Trends in Pharmacy, Pharmaceutical Industry and Education" http://www.pharmacon2007.com
Abstract is available at http://www.pharmaconnectme.com
Global cancer biosimilars market opportunity outlookKuicK Research
"Global Cancer Biosimilars Market Opportunity Outlook" Report Highlight & Findings:
Introduction & Mechanism of Cancer Biosimilars
Global Cancer Biosimilars Market Dynamics
FDA & EMA Guidelines on Development & Marketing of Biosimilars
Cancer Biosimilars Clinical Pipeline by Company, Indication & Phase
Cancer Biosimilars Clinical Pipeline: 100 Biosimilars
Marketed Cancer Biosimilars Clinical Insight
Marketed Cancer Biosimilars: 15 Biosimilars
Global cancer biosimilars market opportunity outlookKuicK Research
"Global Cancer Biosimilars Market Opportunity Outlook" Report Highlight & Findings:
Introduction & Mechanism of Cancer Biosimilars
Global Cancer Biosimilars Market Dynamics
FDA & EMA Guidelines on Development & Marketing of Biosimilars
Cancer Biosimilars Clinical Pipeline by Company, Indication & Phase
Cancer Biosimilars Clinical Pipeline: 100 Biosimilars
Marketed Cancer Biosimilars Clinical Insight
Marketed Cancer Biosimilars: 15 Biosimilars
Global gene therapy market & pipeline insightKuicK Research
“Global Gene Therapy Market & Pipeline Insight” Market Highlight:
Gene Therapy Market Overview
Significance of Gene Therapy in Cancer Therapeutics
Current Applications of Gene Therapy to Cancer Treatment
Gene Therapy Market Dynamics: Drivers, Challenges & Future Outlook
FDA & AMA Guidelines for Gene Therapy
Gene Therapy Pipeline by Phase, Indications, Country & Company
Gene Therapy Pipeline: 246 Drugs
Marketed Gene Therapy: 2 (Gendicine & Rexin-G)
Cancer Gene Therapy Pipeline: 69 Drugs
The transient protein expression market was valued at US$ 660.00 million in 2019 and is projected to reach US$ 983.10 million by 2027; it is expected to grow at a CAGR of 5.3% from 2020 to 2027.
Cancer immunomodulators market & pipeline insight 2020KuicK Research
"Cancer Immunomodulators Market & Pipeline Insight 2020" Report Highlights:
Introduction & Need of Cancer Immunomodulators
Cancer Immunomodulators Mechanism
Cancer Immunomodulators Clinical Pipeline By Company, Indication & Phase
Cancer Immunomodulators Clinical Pipeline: 747 Cancer Immunomodulators Drugs
Majority Cancer Immunomodulators in Preclinical Phase: 300 Marketed Cancer Immunomodulators Clinical Insight
Marketed Cancer Immunomodulators: 47
Cancer Immunomodulators Drug Patent Analysis
Biopharmaceuticals are medicinal drugs which are produced through biotechnology methods such as recombinant DNA techniques, fermentation, hybridoma techniques, and purification processes. Biopharmaceutical production involves the usage of biological sources, either live organisms or their active components. They are made up of proteins and nucleic acids and target specific diseases and patients groups. Biopharmaceuticals are used in the treatment of various chronic diseases such as cardiovascular, metabolic, neurological, cancer, and other rare diseases for which there are no available treatments.
Exploring Molecular Targets for Repositioning of Hypertensive DrugsYogeshIJTSRD
Drug repositioning or drug repurposing or drug profiling is the discovery of new applications for approved or failed drug.. Drug repositioning is the development of new approved drug applications. The cost of bringing a medicine to the market is around one million which include clinical and preclinical trials. Repositioning of drugs help in cutting down costs as well as time involve in intial validation and authorization. The procedure involved in Drug repositioning is generally performed during the drug development phase to modify or extend an active molecules distribution line. On a fundamental level, repositioning opportunities exist because drugs perturb multiple biological entities and engage themselves in multiple biological processes. Therefore, a drug can play multiple roles or perform a various mode of actions that are responsible for its pharmacology. Hypertension, is a condition that causes increase in the risk of cardiovascular diseases. In this study an attempt has been made to reposition hypertensive drugs for different diseases by exploring molecular targets of hypertensive drugs. Consider that they often need to be administered for long periods of time, often over whole life time Side effects although present, have been found safe enough to be used for such long durations, hence repurposing these drugs for other diseases may be beneficial with limited side effects. Bhawna Singh | Asmita Das "Exploring Molecular Targets for Repositioning of Hypertensive Drugs" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-5 | Issue-3 , April 2021, URL: https://www.ijtsrd.com/papers/ijtsrd39910.pdf Paper URL: https://www.ijtsrd.com/biological-science/bioinformatics/39910/exploring-molecular-targets-for-repositioning-of-hypertensive-drugs/bhawna-singh
Global cancer cdk inhibitors market & clinical pipeline outlook 2022KuicK Research
“Global Cancer CDK Inhibitors Market and Clinical Pipeline Outlook 2022” report highlights:
* Selectivity and Working Mechanism of a Cancer CDKs Inhibitor
* Recent Advances in the CDKs Related Cancer Therapy
* Global Cancer CDK Inhibitors Clinical Trials Insight: 45 Drugs in Pipeline
* Market Opportunity Assessment: More Than US$ 20 Billion (2022)
* Price Analysis of Cancer CDKs Inhibitors:
* Sales Analysis of Available Drugs: More Than US$ 2 Billion (2017)
Cd antigen cancer therapy market outlook & clinical trials insight 2023KuicK Research
“CD Antigen Cancer Therapy Market Outlook & Clinical Trials Insight 2023” report highlights:
• Market Opportunity Assessment: More than US$ 60 Billion by 2023
• Clinical & Patent Insight on 17 Commercialize CD Antigen Drugs
• Clinical & Licensing Insight on 184 CD Antigens in Clinical Pipeline
• Dosage & Price Analysis on Key Drugs
• Mechanism of CD Antigen Cancer Therapeutics
• Cancer CD Antigens Clinical Pipeline Dominated by CD20 Antigen: 50 Drugs
• Cancer CD Antigen Inhibitors Clinical Pipeline by Company, Indication & Phase
Global orphan drug market designation status clinical pipeline trials insigh...KuicK Research
“Global Orphan Drug Market & Clinical Pipeline Insight 2023” Report Highlights:
• Clinical Insight on 800 Orphan Drugs
• Patent Insight, Orphan Designated Indication & Region/Country
• Marketed Orphan Drugs: More Than 300
• Maximum Orphan Designated Drugs in Phase-II: More Than 200
• Global Orphan Drug Designation Criteria
• FDA & EMA Guidelines
“US Shale Gas Industry Analysis” Report Highlight:
* US Shale Gas Industry Overview
* Shale Gas Exploration, Technical and Technology Aspects
* US Shale Gas Reserve Analysis: Technical & Recoverable Reserves
* Investments in Shale Gas Exploration & Production
* US Shale Gas Sector Dynamics
* Shale Boom to Drive LNG Export Projects
Download Us biosimilars market opportunity & clinical pipeline analysisKuicK Research
“US Biosimilars Market Opportunity & Clinical Pipeline Analysis” Report Highlight:
* US Biosimilars Market Introduction
* US Biosimilars Regulatory Scenario
* Unique Features of US Biosimilars Market
* Impact of Biosimilars in US Market
* Impact of Reimbursement Policies on US Biosimilars Market
* Zarxio: First Approved Biosimilar in US
* US Biosimilar Clinical Pipeline By Company, Indication & Phase
* US Biosimilar Clinical Pipeline: 104 Biosimilars
* Marketed Biosimilars: 1 Biosimilar*
Download Uae nuclear power sector opportunity analysisKuicK Research
“UAE Nuclear Power Sector Opportunity Analysis” Report Highlight:
* UAE Energy Policy beyond Oil & Gas
* UAE Nuclear Power Sector Overview
* UAE Nuclear Power Sector Dynamics
* Nuclear Power Sector Management & Regulatory Framework
* Nuclear Power Sector Regulations
* Details of Nuclear Power Plants in UAE
* UAE Nuclear Power Sector Future Outlook
Download Turkey wind power sector outlook 2017KuicK Research
“Turkey Wind Power Sector Outlook 2017” gives comprehensive insight on following aspect related to wind power sector development in Turkey:
* Wind Power Sector Overview
* Wind installed Capacity & Generation
* Operating Wind Farms by Province & Company
* Onshore & Offshore Wind Potential
* Emerging Trends
* Policy Framework
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Download South korea wind power sector analysis 2013KuicK Research
“South Korea Wind Power Sector Analysis 2013” research report discusses following aspect related to emerging wind power sector in South Korea:
* Current Sector Trends
* Onshore & Offshore Wind Potential
* Wind Power Sector Indicators
* Operating Wind Farms
* Future Outlook & Sector Emerging Trends
* Regulatory & Policy Framework
* Competitive Landscape
Download Saudi arabia airport privatization opportunity outlook 2022KuicK Research
“Saudi Arabia Airport Privatization Opportunity Outlook 2022” report highlights:
Saudi Arabia Aviation Industry Overview
Privatization in Saudi Arabia
Investment and Expansion Opportunities for International Investors
Civil Aviation Laws and Policies Framework
Ongoing Privatization Projects
Privatization Build - Operateandndash;Transfer (BOT) Business Model
Download Non hodgkin lymphoma therapeutics market & pipeline insightKuicK Research
“Non Hodgkin Lymphoma Therapeutics Market & Pipeline Insight” Report Highlight:
Global Non Hodgkin Lymphoma Market Overview
Mechanism of Non Hodgkin Lymphoma Therapeutics
Global Non Hodgkin Lymphoma Pipeline by Type, Phase & Company
Global Non Hodgkin Lymphoma Pipeline: 204 Drugs
Majority of the Drugs are in Phase-I: 54 Drugs
Marketed Drugs for Non Hodgkin Lymphoma: 30 Drugs
Patent Analysis by Country, Year & Compositions
Download Nanoparticle drug delivery market & clinical pipeline insightKuicK Research
“Nanoparticle Drug Delivery Market & Clinical Pipeline Insight” Report Highlights:
Nanoparticle Drug Delivery Market Overview
Nanoparticle Drug Delivery Mechanism
Clinical Pipeline by Phase & Target Indications
Drug Profiles in Report: 190
Majority of Nanoparticle Drug in Preclinical Phase: 70
Marketed Nanoparticle Drugs: 12
Suspended & Discontinued Drug Profiles
Download Japan generics drug market outlook 2020KuicK Research
“Japan Generics Drug Market Outlook 2020” Report Highlights:
Introduction to Japanese Generic Drug Market
Attractiveness of Japanese Generic Market
Super Generics in Japan
Japan Healthcare System & Generic Drugs
Different Parameters for Generic & Branded Drugs
Comparison of Generic Drugs in US & Japan
Japan Generics Drug Market Analysis
Japan Generics Drug Market Future Prospects
Download India urban and industrial waste to energy marketKuicK Research
The Urban and Industrial waste based power projects have been witnessing upward trend in recent years driven by increasing investments from private sector and ongoing government initiatives to promote generation of power from urban and industrial waste. The overall installed capacity of grid connected waste power projects surpassed 70 MW by end of 2011 as compare to more than 90 MW of off grid waste base power projects.
Considering the huge potential to convert waste to energy in India, the Ministry of Environment and Forests had formulated the Municipal Solid Wastes Management and Handling Rules in 2000. Waste to Energy is understood as a renewable technology, and comes under the overall guidance and facilitation of the Ministry of Non Renewable Energy of India, which has announce finacila incentives and assistance programme in.
Download India nuclear power sector generation and investment opportunity out...KuicK Research
“India Nuclear Power Sector Generation and Investment Opportunity Outlook 2032” report highlights:
India Nuclear Power Sector Overview
India Nuclear Power Sector Indicators
India Existing and upcoming Nuclear Power Plants Overview
Indian Nuclear Power Regulatory and Policy Framework
India Nuclear Power Plants Infrastructure
India Nuclear Fuel Supply Scenario
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
1. Recombinant Therapeutic Proteins Market
KuicK Research Page 1
Proteins are known to be the building blocks of life, and as a part of the natural metabolism,
they are synthesized by all living forms. Some proteins, such as enzymes, tend to serve as
biocatalysts, which help in increasing the rate of metabolic reactions. There are other types
of proteins which form the cytoskeleton. There is a significant role played by proteins in
functions like cell signaling, immune responses, cell adhesion, and the cell cycle. In
industries, proteins are commercially produced by using genetic engineering and protein
engineering. There are many sectors such as the biopharmaceutical industry, the enzyme
industry, and the agricultural industry, which are significantly benefitted from native and
recombinant proteins. In return the products manufactured in these industries tend to
support the fields of medicine, diagnostics, food, nutrition, detergents, textiles, leather,
paper, pulp, polymers and plastics.
Recombinant protein is a modified version of protein which is produced through different
methods in order to further generate large quantities of proteins, modify gene sequences and
eventually manufactures commercial products. The recombinant protein is formed with the
help of specialized vehicles which are called vectors. The recombinant technology is the
entire process which is involved in the formation of a recombinant protein.
Generally, the therapeutic proteins include antibody-based drugs, anticoagulants, blood
factors, bone morphogenetic proteins, engineered protein scaffolds, enzymes, Fc fusion
proteins, growth factors, hormones, interferons, interleukins, and thrombolytic. Of the total
biopharmaceuticals which is being currently marketed, the dominant segment is accounted
for by the recombinant therapeutic protein drugs. The major areas of applications are
diabetes, dwarf¬ism, myocardial infarction, congestive heart failure, cerebral apoplexy,
multiple sclerosis, neutropenia, thrombocytopenia, anemia, hepatitis, rheumatoid arthritis,
asthma, Crohn’s disease and cancers therapies.
There are many driving forces for the recombinant proteins market. These include the
introduction of new protein therapeutics and enhanced investments which are likely to
significantly impact the growth of this industry in a positive manner. Additionally, the rapidly
rising number of clinical trials would also help in surfacing the optimistic performance of the
industry.
2. Recombinant Therapeutic Proteins Market
KuicK Research Page 2
In terms of segments, the major revenue-generating segments of the recombinant therapeutic
protein market include monoclonal antibody, Insulin, Interferon Beta, G-CSF and coagulation
factors. At present, owing to the fact that large number of companies is focusing their
efforts in developing innovative treatment options using mAbs, this segment is currently the
most dominant in terms of growth rate. In terms of the regional scenario of the recombinant
proteins market, it has been observed that the US has been and would continue to account for
the largest share of the global pie followed by the European countries. The emerging nations
which are likely to be the future revenue generators for this market include the Asian and
Middle-Eastern region, which is having a growing therapeutic market owing to improving
economic scenario and financial capability of people.
The future years are likely to witness the protein therapeutics and specifically recombinant
proteins dominating the overall pharmaceutical industry. Though in terms of market size, the
protein therapeutics market is significantly smaller than the overall pharmaceutical market,
on a comparative basis, the growth of the protein therapeutics market is significantly higher
than the growth of the overall pharmaceutical market. With the introduction and increasing
adoption of “recombinant technology”, it is most likely that the protein therapeutics market
would flourish in the coming years. This technology involves the development of therapies
through designing the required protein structure synthetically. There is considerable amount
of research being done in this field by both the private companies and the academicians and
researchers at the universities and research centers. Their efforts are being directed towards
successfully develop protein-based therapies for curing diseases like HIV/AIDS, cancer,
hormonal imbalance and neurological disorders. Further, because of advantages like their
higher specificity and effectiveness as compared to other drug forms, the protein therapies
have become highly attractive for the pharmaceuticals companies who are rapidly shifting
their focus towards this field.
“Recombinant Therapeutic Proteins Market & Pipeline Analysis” Report Highlights:
Global Market Overview
Mechanisms of Recombinant Protein Production
Types of Recombinant DNA Technology
Clinical Pipeline by Phase, Indication, Company, & Country
3. Recombinant Therapeutic Proteins Market
KuicK Research Page 3
Marketed Recombinant Therapeutic Protein Drugs Clinical Insight
Recombinant Therapeutic Proteins Clinical Pipeline: 340 Drugs
Marketed Recombinant Therapeutic Protein Drugs : 83 Drugs
Majority Recombinant Therapeutic Proteins in Preclinical Phase: 128 Drugs
For Report Sample Contact: neeraj@kuickresearch.com
Report TOC
1. What Are Recombinant Proteins?
1.1 Recombinant Proteins Overview
1.2 History of Recombinant Proteins
2. Why There Exist Need for Recombinant Proteins?
3. Different Types of Recombinant DNA Technology
4. Mechanisms of Recombinant Protein Production
4.1 Recombinant Protein Production & Expression
4.2 Different Methods of Protein Production
4.3 Process for Producing Recombinant Proteins
5. Global Recombinant Therapeutic Proteins Market Overview
5.1 Current Market Scenario
5.2 Recombinant Proteins Clinical Pipeline Overview
6. Global Recombinant Therapeutic Proteins Market Dynamics
4. Recombinant Therapeutic Proteins Market
KuicK Research Page 4
6.1 Market Drivers
6.2 Challenges
7. Recombinant Therapeutic Proteins Market Future Growth Outlook
8. Recombinant Therapeutic Proteins Clinical Pipeline by Phase,
Indication, Company, & Country
8.1 Research till Registration
8.2 Marketed Recombinant Therapeutic Protein Drugs
8.3 Suspended & Discontinued Drugs in Clinical Pipeline
9. Recombinant Erythropoietins Clinical Pipeline by Phase, Indication,
Company, & Country
9.1 Research till Registration
9.2 Marketed Recombinant Erythropoietin Drugs
9.3 Suspended & Discontinued Drugs in Clinical Pipeline
10. Recombinant Therapeutic Fusion Proteins Clinical Pipeline by Phase,
Indication, Company, & Country
10.1 Research till Registration
10.2 Marketed Recombinant Fusion Protein Drugs
10.3 Suspended & Discontinued Drugs in Clinical Pipeline
11. Competitive Landscape
11.1 Boehringer Ingelheim
11.2 Bristol-Myers Squibb
11.3 Celldex Therapeutics
11.4 Eli Liily
11.5 GlaxoSmithKline
11.6 Merck
11.7 Novartis
5. Recombinant Therapeutic Proteins Market
KuicK Research Page 5
11.8 Regeneron Pharmaceuticals
11.9 Roche
11.10 Shire Pharmaceuticals
List of Figures
Figure 1-1: Most Commonly Used Recombinant Protein Products
Figure 1-2: Biopharmaceutical Approval in European Union & US During 2008-2013
Figure 3-1: Recombinant DNA Technologies
Figure 4-1: Process for Producing Recombinant Proteins
Figure 5-1: Global Biologics Market Classification
Figure 5-2: Global Protein Therapeutics Market (US$ Billion), 2013-2020
Figure 5-3: Global Therapeutic Protein Market by Region (%), 2014
Figure 5-4: Share of Producing Agents for Recombinant Proteins, 2014
Figure 5-5: Recombinant Therapeutic Proteins Clinical Pipeline by Phase (%), 2014
Figure 5-6: Recombinant Therapeutic Proteins Clinical Pipeline by Phase (Number), 2014
Figure 5-7: No Development Reported in Recombinant Therapeutic Proteins Clinical Pipeline
by Phase (%), 2014
Figure 5-8: No Development Reported in Recombinant Therapeutic Proteins Clinical Pipeline
by Phase (Number), 2014
Figure 5-9: Discontinued Recombinant Therapeutic Proteins Clinical Pipeline by Phase (%),
2014
Figure 5-10: Discontinued Recombinant Therapeutic Proteins Clinical Pipeline by Phase
(Number), 2014
Figure 5-11: Suspended Recombinant Therapeutic Proteins Clinical Pipeline by Phase (%), 2014
Figure 5-12: Suspended Recombinant Therapeutic Proteins Clinical Pipeline by Phase
(Number), 2014
Figure 5-13: Recombinant Erythropoietins Clinical Pipeline by Phase (%), 2014
Figure 5-14: Recombinant Erythropoietins Clinical Pipeline by Phase (Number), 2014
Figure 5-15: Discontinued Recombinant Erythropoietins Clinical Pipeline by Phase (%), 2014
Figure 5-16: Discontinued Recombinant Erythropoietins Clinical Pipeline by Phase (Number),
2014
Figure 5-17: Recombinant Therapeutic Fusion Proteins Clinical Pipeline by Phase (%), 2014
6. Recombinant Therapeutic Proteins Market
KuicK Research Page 6
Figure 5-18: Recombinant Therapeutic Fusion Proteins Clinical Pipeline by Phase (Number),
2014
Figure 5-19: No Development Reported in Recombinant Therapeutic Fusion Proteins Clinical
Pipeline by Phase (%), 2014
Figure 5-20: No Development Reported in Recombinant Therapeutic Fusion Proteins Clinical
Pipeline by Phase (Number), 2014
Figure 5-21: Discontinued Recombinant Therapeutic Fusion Proteins Clinical Pipeline by Phase
(%), 2014
Figure 5-22: Discontinued Recombinant Therapeutic Fusion Proteins Clinical Pipeline by Phase
(Number), 2014
List of Tables
Table 1-1: First Generation of Therapeutic Proteins
Table 1-2: Second Generation of Therapeutic Proteins
Table 1-3: Monoclonal Antibodies
For Report Sample Contact: neeraj@kuickresearch.com