VERSO: Ecosystem Responses in the Southern OceanBruno Danis
General presentation of the BELSPO funded vERSO (Ecosystem Resoponses to Changes in the Southern Ocean) project. More information on www.versoproject.be
A reunião anual de 2015 da Rede Global Biodiversity Heritage Library será realizada no Brasil e abordará o estado de desenvolvimento da Biodiversity Heritage Library (BHL) e sistemas de informação em Biodiversidade.
Organizada pelos Programas SciELO e BIOTA da FAPESP, a reunião está dirigida para pesquisadores e profissionais relacionados com biodiversidade e informação científica. O programa científico contará com autoridades e especialistas nacionais e internacionais.
A Rede Global da BHL (gBHL) conta com a participação da África do Sul, Austrália, Brasil, China, Egito, Estados Unidos e Europa. A BHL trabalha de forma colaborativa em prol do acesso aberto à literatura em biodiversidade como parte da comunidade de biodiversidade global.
GBIF & GRScicoll, Høstseminar Norges museumsforbunds Seksjon for natur, 2021-...Dag Endresen
Norges museumsforbunds Seksjon for natur og Naturhistorisk museum ønsker velkommen til Høstseminar! Natur i museum – forskning, formidling og samlinger
24. og 25. november 2021
Dag Endresen (GBIF) (20 min foredrag, 10 min spørsmål)
Digitalisering og GBIF. Registering av samlinger i GrSciColl og Wikidata og publisering av samlingsdata i GBIF.
VERSO: Ecosystem Responses in the Southern OceanBruno Danis
General presentation of the BELSPO funded vERSO (Ecosystem Resoponses to Changes in the Southern Ocean) project. More information on www.versoproject.be
A reunião anual de 2015 da Rede Global Biodiversity Heritage Library será realizada no Brasil e abordará o estado de desenvolvimento da Biodiversity Heritage Library (BHL) e sistemas de informação em Biodiversidade.
Organizada pelos Programas SciELO e BIOTA da FAPESP, a reunião está dirigida para pesquisadores e profissionais relacionados com biodiversidade e informação científica. O programa científico contará com autoridades e especialistas nacionais e internacionais.
A Rede Global da BHL (gBHL) conta com a participação da África do Sul, Austrália, Brasil, China, Egito, Estados Unidos e Europa. A BHL trabalha de forma colaborativa em prol do acesso aberto à literatura em biodiversidade como parte da comunidade de biodiversidade global.
GBIF & GRScicoll, Høstseminar Norges museumsforbunds Seksjon for natur, 2021-...Dag Endresen
Norges museumsforbunds Seksjon for natur og Naturhistorisk museum ønsker velkommen til Høstseminar! Natur i museum – forskning, formidling og samlinger
24. og 25. november 2021
Dag Endresen (GBIF) (20 min foredrag, 10 min spørsmål)
Digitalisering og GBIF. Registering av samlinger i GrSciColl og Wikidata og publisering av samlingsdata i GBIF.
Digital & Discovery @ Smithsonian Libraries 2013. Martin R. Kalfatovic. Smithsonian Libraries Advisory Board Meeting. Smithsonian Conservation Biology Institute, Front Royal, Virginia. 21 May 2013.
Biodiversity Heritage Library - an overview for the Australian MuseumNicole Kearney
This presentation was delivered to the Australian Museum (Sydney Australia) on 17 October 2016. It provides an overview of the Biodiversity Heritage Library (BHL) and its efforts to make the world's biodiversity literature accessible & discoverable (with particular emphasis on scientific artwork, field diaries and taxonomic descriptions).
The Who in Collections: Revealing the Network of Collectors and Determiners o...David Shorthouse
Workshop Invite:
We invite you to bring your extensive knowledge of bats and historic and present-day bat collectors to a special two-hour workshop designed to enable building a master list of the world’s bat collectors.
We will explore the digitally accessible bat specimen records in the Families Hipposideridae and Rhinolophidae and actively link these to the people who collected and/or identified them. This will be a state of the art, new approach in which you will also receive brief training on the use of ORCID, Wikidata, and a new online resource called Bionomia. No technical skills are required, just your unique, insider knowledge of chiropterologists and bat collections across the world.
You will be helping to create links in the biodiversity knowledge network that will aid in the uncovering of what is known, but currently hidden, and enable future digitization efforts. Through your work and Bionomia, you may also discover the research in which your specimens may have played a part, and just where your specimens are now and who else has looked at them. You’ll be participating in a pilot run for this new kind of community data enhancement campaign helping us discover the potential for doing this in the future for other taxa (e.g., Revealing the Who in Bird Collecting).
Overview of the problems of Reference Rot and what actions to take to ensure the persistence of the digital scholarly record. Presented by Peter Burnhill with Adam Rusbridge & Muriel Mewissen, EDINA, University of Edinburgh, UK; Herbert Van De Sompel, Los Alamos National Laboratory Research Library, USA; Gaelle Bequet, ISSN International Centre, France; at Towards Open Science, LIBER, London, June 2015.
Discussion 1 Blue GoldRead the paragraphs below and respond to .docxcuddietheresa
Discussion 1: Blue Gold
Read the paragraphs below and respond to the questions.
Environmentalists believe that the world is running out of clean drinking water. Over 97% of the world's water is salt water found in the oceans. Salt water is unsuitable for drinking without expensive desalination. Of the fresh water in the world, most is locked in frozen form in the polar ice caps and glaciers and therefore unavailable. This leaves only a small percentage in groundwater, lakes, and rivers that could be available for drinking, industry, and irrigation. However, some of that water is polluted and unsuitable.
Water has always been the most valuable commodity in the Middle East, even more valuable than oil. But as fresh water becomes limited and the world's population grows, the lack of sufficient clean water is becoming a worldwide problem.
The combination of increasing demand and dwindling supply has attracted global corporations who want to sell water. Water is being called the "blue gold" of the twenty-first century, and an issue has arisen regarding whether the water industry should be privatized. That is, could water rights be turned over to private companies to deliver clean water and treat wastewater at a profit, similar to the way oil and electricity are handled? Private companies have the resources to upgrade and modernize water delivery and treatment systems, thereby conserving more water. However, opponents of this plan claim that water is a basic human right required for life, not a need to be supplied by the private sector. In addition, a corporation can certainly own the pipelines and treatment facilities, but who owns the rights to the water? For example, North America's largest underground aquifer, the Ogallala, covers 175,000 square miles under several states in the southern Great Plains. If water becomes a commodity, do we allow water to be taken away from people who cannot pay in order to give it to those who can?
Clovis has water concerns as well. Check out the links below for information and feel free to do your own research to bring into the discussion.
https://www.epa.gov/pfas (Links to an external site.)
https://www.epa.gov/ground-water-and-drinking-water/drinking-water-health-advisories-pfoa-and-pfos (Links to an external site.)
https://www.kcbd.com/2019/02/25/cannon-air-force-base-water-contamination-shuts-down-clovis-dairy/ (Links to an external site.)
https://abc7amarillo.com/news/local/air-force-responds-to-questions-surrounding-contaminated-water-in-clovis (Links to an external site.)
https://www.cityofclovis.org/?p=6241 (Links to an external site.)
Questions:
1. Do you agree that the water industry should be privatized? Why or why not?
2. Is access to clean water a "need" or a "right"? If it is a right, who pays for that right?
3. Because water is a shared resource, everyone believes they can use water, but few people feel responsible for conserving it. What can you do to conserve water?
4. Do you t ...
The Biodiversity Heritage Library & Botany: Empowering Discovery through Free...Martin Kalfatovic
The Biodiversity Heritage Library & Botany: Empowering Discovery through Free Access to Biodiversity Knowledge. Martin R. Kalfatovic. Botany 2018. Rochester, MN. 24 July 2018.
Outreach Strategies to Engage Citizen Scientists: Insights from the Biodivers...costantinog
Presentation delivered at the joint SPNHC.TDWG 2018 conference on Dunedin, NZ regarding outreach strategies used by the Biodiversity Heritage Library to engage citizen scientists with projects.
Synergies with the Ocean Biogeographic Information System (OBIS) and the International Coastal Atlas Network (ICAN) by Robert Branton (Ocean Tracking Network - OTN)
Digital & Discovery @ Smithsonian Libraries 2013. Martin R. Kalfatovic. Smithsonian Libraries Advisory Board Meeting. Smithsonian Conservation Biology Institute, Front Royal, Virginia. 21 May 2013.
Biodiversity Heritage Library - an overview for the Australian MuseumNicole Kearney
This presentation was delivered to the Australian Museum (Sydney Australia) on 17 October 2016. It provides an overview of the Biodiversity Heritage Library (BHL) and its efforts to make the world's biodiversity literature accessible & discoverable (with particular emphasis on scientific artwork, field diaries and taxonomic descriptions).
The Who in Collections: Revealing the Network of Collectors and Determiners o...David Shorthouse
Workshop Invite:
We invite you to bring your extensive knowledge of bats and historic and present-day bat collectors to a special two-hour workshop designed to enable building a master list of the world’s bat collectors.
We will explore the digitally accessible bat specimen records in the Families Hipposideridae and Rhinolophidae and actively link these to the people who collected and/or identified them. This will be a state of the art, new approach in which you will also receive brief training on the use of ORCID, Wikidata, and a new online resource called Bionomia. No technical skills are required, just your unique, insider knowledge of chiropterologists and bat collections across the world.
You will be helping to create links in the biodiversity knowledge network that will aid in the uncovering of what is known, but currently hidden, and enable future digitization efforts. Through your work and Bionomia, you may also discover the research in which your specimens may have played a part, and just where your specimens are now and who else has looked at them. You’ll be participating in a pilot run for this new kind of community data enhancement campaign helping us discover the potential for doing this in the future for other taxa (e.g., Revealing the Who in Bird Collecting).
Overview of the problems of Reference Rot and what actions to take to ensure the persistence of the digital scholarly record. Presented by Peter Burnhill with Adam Rusbridge & Muriel Mewissen, EDINA, University of Edinburgh, UK; Herbert Van De Sompel, Los Alamos National Laboratory Research Library, USA; Gaelle Bequet, ISSN International Centre, France; at Towards Open Science, LIBER, London, June 2015.
Discussion 1 Blue GoldRead the paragraphs below and respond to .docxcuddietheresa
Discussion 1: Blue Gold
Read the paragraphs below and respond to the questions.
Environmentalists believe that the world is running out of clean drinking water. Over 97% of the world's water is salt water found in the oceans. Salt water is unsuitable for drinking without expensive desalination. Of the fresh water in the world, most is locked in frozen form in the polar ice caps and glaciers and therefore unavailable. This leaves only a small percentage in groundwater, lakes, and rivers that could be available for drinking, industry, and irrigation. However, some of that water is polluted and unsuitable.
Water has always been the most valuable commodity in the Middle East, even more valuable than oil. But as fresh water becomes limited and the world's population grows, the lack of sufficient clean water is becoming a worldwide problem.
The combination of increasing demand and dwindling supply has attracted global corporations who want to sell water. Water is being called the "blue gold" of the twenty-first century, and an issue has arisen regarding whether the water industry should be privatized. That is, could water rights be turned over to private companies to deliver clean water and treat wastewater at a profit, similar to the way oil and electricity are handled? Private companies have the resources to upgrade and modernize water delivery and treatment systems, thereby conserving more water. However, opponents of this plan claim that water is a basic human right required for life, not a need to be supplied by the private sector. In addition, a corporation can certainly own the pipelines and treatment facilities, but who owns the rights to the water? For example, North America's largest underground aquifer, the Ogallala, covers 175,000 square miles under several states in the southern Great Plains. If water becomes a commodity, do we allow water to be taken away from people who cannot pay in order to give it to those who can?
Clovis has water concerns as well. Check out the links below for information and feel free to do your own research to bring into the discussion.
https://www.epa.gov/pfas (Links to an external site.)
https://www.epa.gov/ground-water-and-drinking-water/drinking-water-health-advisories-pfoa-and-pfos (Links to an external site.)
https://www.kcbd.com/2019/02/25/cannon-air-force-base-water-contamination-shuts-down-clovis-dairy/ (Links to an external site.)
https://abc7amarillo.com/news/local/air-force-responds-to-questions-surrounding-contaminated-water-in-clovis (Links to an external site.)
https://www.cityofclovis.org/?p=6241 (Links to an external site.)
Questions:
1. Do you agree that the water industry should be privatized? Why or why not?
2. Is access to clean water a "need" or a "right"? If it is a right, who pays for that right?
3. Because water is a shared resource, everyone believes they can use water, but few people feel responsible for conserving it. What can you do to conserve water?
4. Do you t ...
The Biodiversity Heritage Library & Botany: Empowering Discovery through Free...Martin Kalfatovic
The Biodiversity Heritage Library & Botany: Empowering Discovery through Free Access to Biodiversity Knowledge. Martin R. Kalfatovic. Botany 2018. Rochester, MN. 24 July 2018.
Outreach Strategies to Engage Citizen Scientists: Insights from the Biodivers...costantinog
Presentation delivered at the joint SPNHC.TDWG 2018 conference on Dunedin, NZ regarding outreach strategies used by the Biodiversity Heritage Library to engage citizen scientists with projects.
Synergies with the Ocean Biogeographic Information System (OBIS) and the International Coastal Atlas Network (ICAN) by Robert Branton (Ocean Tracking Network - OTN)
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
Comparing Evolved Extractive Text Summary Scores of Bidirectional Encoder Rep...University of Maribor
Slides from:
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Track: Artificial Intelligence
https://www.etran.rs/2024/en/home-english/
This presentation explores a brief idea about the structural and functional attributes of nucleotides, the structure and function of genetic materials along with the impact of UV rays and pH upon them.
Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
What is greenhouse gasses and how many gasses are there to affect the Earth.moosaasad1975
What are greenhouse gasses how they affect the earth and its environment what is the future of the environment and earth how the weather and the climate effects.
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...Sérgio Sacani
Since volcanic activity was first discovered on Io from Voyager images in 1979, changes
on Io’s surface have been monitored from both spacecraft and ground-based telescopes.
Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large
Binocular Telescope, show evidence of a major resurfacing event on Io’s trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images
show that a plume deposit from a powerful eruption at Pillan Patera has covered part
of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Io’s surface using adaptive
optics at visible wavelengths.
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
2. • There are known knowns, things we know
that we know
• There are known unknowns, things we
now know we don’t know
• But there are also unknown unknowns,
things we do not know we don’t know
32. Using other people’s identifiers
is hard work and scary
• Hard work - you have to find their identifiers
• Scary - what happens if other person breaks
their identifiers?
• Solution: make it easy to find them, and make
them robust (e.g., CrossRef and DOIs)
51. In an attempt to live up to that increasing
demand for documentation, the leadership of
the Natural History Museum of Denmark has
issued an order to its curatorial staff - The
staff members are requested to document
which publications from 2011, written
entirely by external scientists, that in one way
or another are based on material in the
collections of the Museum.
http://markmail.org/message/opv2we7fkmro2nen@TAXACOM