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RAD Biomed Incubator
The Israeli incubator program started in 1991 to provide a
sheltered environment for scientists and entrepreneurs from the
former USSR

RBM was established in 1992 as general incubator, refocused in 1998
to biotech

Located in Tel-Aviv

Owned by the RAD group of companies

Six active graduate companies

                MaimoniDex RA


               InnoScent Ltd
The RAD Biomed Portfolio
             9 Incubator companies

                                                ARIO MEDICA
 Drug-delivery pump         Gene therapy        Peripheral atherectomy




 Improved enzymes      Molecular diagnostics      Cord-blood harvesting




TouchMed               OccuPharma                    TissueDetect
 Endoscopy            Opthalmic drug-delivery    Epidural-space detection
Our Philosophy
RBM is a biotech incubator that serves as a natural interface between
the world of Israeli academic research and the global biotech industry

Long term vision: to build viable businesses and to create sustainable
benefits to the economy and a significant return to investors and to
the entrepreneurs

The goal of the incubation period is to prove the
technological concept and its feasibility and to
advance it towards commercialization.



To attain our goal we establish for each project a business model &
strong IP position, and demonstrate that it can attain profitability
                    in a targeted market segment
The Deal Flow
Projects are admitted to RBM either as a concept or as a small team
with molecule/technology & executive-summary/IP/work-plan etc.

Deal flow is generated in the following manner:
Entrepreneurs approach the incubator
Via our working relationship with TTOs
Proactive search for projects in Israeli academia and
hospitals
Personal contacts
Screening the deal-Flow
             Rad BioMed Functions as a mini Pre-Seed VC


Incoming
                   Test Criteria
deal- flow
                   •   Clinical Need
                   •   Team
                                         Product      RAD BioMed’s
                   •   Market           Positioning    Investment
                   •   IP
Proactive                                              Committee
                   •   Technology
search
                   •   Project status
for projects


                                                         Approval
Nurturing The Young Project
    Our Nurturing Approach:
       Mapping the needs (to reach the long-term goal), Assessing all the
       available resources at set-up, Implementing and supporting

      While keeping our focus on the startup’s long term goals,
       we build the company’s work-plan & activities step-
       by-step to position it for the next round of financing

     RBM provides the incubator projects :
• Management & legal and financial support
•    Business development and clinical consulting
•    IP strategy and regulatory & reimbursement planning
•    Extensive lab space for R&D
Nurturing The People
In an ideal world, the “unskilled” entrepreneur would step aside and
make room for a “seasoned” business-oriented project-leader


In the “real world” we are limited by budget constraints, so we
appoint a project manager and then mentor and coach …


Coaching, coaching, coaching:
                    coaching
 Active interaction with project managers
 Creating a “business-oriented” thinking process
 Adhering to work-plan
Funding
RBM incubator is owned and funded by the
Chairman of the RAD Group of Companies

The projects are funded by the Israeli
Government and matching-funds are
 provided by the owner of RBM

 Additional funding may be provided by
business angels before or upon entry,
and/or during the incubation period

Our companies seek VC or corporate
funding upon graduation and at-times
 also during the incubation period



  RBM maintains an active role in the fundraising process
Task Oriented Management Team
                         Idan Tamir, Ph.D.
Binah Baum, Ph.D. MBA     President & CEO
Director, Business Dev                       Shoshi Keynan, Ph.D.
                                               Project Manager



 Clinical & regulatory
                              project              IP experts
        experts




   Medical device                             Drug development
    consultants           RAD group of            specialists
                           companies
Handling The Maturing Company
             Building Value To The Next Level

√ Demonstrating proof of concept –critical milestone

√ Creating a strong IP position with freedom to operate
√ Initiating regulatory procedures – what does the FDA look for?
   Initiating discussion with regulatory consultants

√ Preparing succinct business plan for next investment round
√ Creating a professional advisory board & appointing a medical director
√ Initiating alliances with companies e.g. FP7 consortia
√ Helping to secure follow-up financing / alliances with strategic partners
Is project funding sufficient for required tasks?
                                                           Weaknesses
will the tight budget allow us to chose the “perfect”
manager?

How well do Government financing programs adapt
to changing needs?

Distance from global markets



                      Support & coaching to company management
                      Responsibility and accountability

  Strengths           Focus on value creation - always market oriented
                      Work-plan within a limited budget
                      Achieving technological POC within these constraints
                      Determination, flexibility & success orientation
What do we need to do in order “to do better” ?


Go Europe:
create alliances
Inclusion of our SMEs in FP7 consortia
Participation of incubator in FP7 consortia
Collaborations betw. our SMEs and clinical-centers
/SMEs in other European bioregions


Incubation of European pre-seed projects in RBM

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Rad Biomed Incubator Heraklion Final Sept 18

  • 1.
  • 2. RAD Biomed Incubator The Israeli incubator program started in 1991 to provide a sheltered environment for scientists and entrepreneurs from the former USSR RBM was established in 1992 as general incubator, refocused in 1998 to biotech Located in Tel-Aviv Owned by the RAD group of companies Six active graduate companies MaimoniDex RA InnoScent Ltd
  • 3. The RAD Biomed Portfolio 9 Incubator companies ARIO MEDICA Drug-delivery pump Gene therapy Peripheral atherectomy Improved enzymes Molecular diagnostics Cord-blood harvesting TouchMed OccuPharma TissueDetect Endoscopy Opthalmic drug-delivery Epidural-space detection
  • 4. Our Philosophy RBM is a biotech incubator that serves as a natural interface between the world of Israeli academic research and the global biotech industry Long term vision: to build viable businesses and to create sustainable benefits to the economy and a significant return to investors and to the entrepreneurs The goal of the incubation period is to prove the technological concept and its feasibility and to advance it towards commercialization. To attain our goal we establish for each project a business model & strong IP position, and demonstrate that it can attain profitability in a targeted market segment
  • 5. The Deal Flow Projects are admitted to RBM either as a concept or as a small team with molecule/technology & executive-summary/IP/work-plan etc. Deal flow is generated in the following manner: Entrepreneurs approach the incubator Via our working relationship with TTOs Proactive search for projects in Israeli academia and hospitals Personal contacts
  • 6. Screening the deal-Flow Rad BioMed Functions as a mini Pre-Seed VC Incoming Test Criteria deal- flow • Clinical Need • Team Product RAD BioMed’s • Market Positioning Investment • IP Proactive Committee • Technology search • Project status for projects Approval
  • 7. Nurturing The Young Project Our Nurturing Approach: Mapping the needs (to reach the long-term goal), Assessing all the available resources at set-up, Implementing and supporting While keeping our focus on the startup’s long term goals, we build the company’s work-plan & activities step- by-step to position it for the next round of financing RBM provides the incubator projects : • Management & legal and financial support • Business development and clinical consulting • IP strategy and regulatory & reimbursement planning • Extensive lab space for R&D
  • 8. Nurturing The People In an ideal world, the “unskilled” entrepreneur would step aside and make room for a “seasoned” business-oriented project-leader In the “real world” we are limited by budget constraints, so we appoint a project manager and then mentor and coach … Coaching, coaching, coaching: coaching Active interaction with project managers Creating a “business-oriented” thinking process Adhering to work-plan
  • 9. Funding RBM incubator is owned and funded by the Chairman of the RAD Group of Companies The projects are funded by the Israeli Government and matching-funds are provided by the owner of RBM Additional funding may be provided by business angels before or upon entry, and/or during the incubation period Our companies seek VC or corporate funding upon graduation and at-times also during the incubation period RBM maintains an active role in the fundraising process
  • 10. Task Oriented Management Team Idan Tamir, Ph.D. Binah Baum, Ph.D. MBA President & CEO Director, Business Dev Shoshi Keynan, Ph.D. Project Manager Clinical & regulatory project IP experts experts Medical device Drug development consultants RAD group of specialists companies
  • 11. Handling The Maturing Company Building Value To The Next Level √ Demonstrating proof of concept –critical milestone √ Creating a strong IP position with freedom to operate √ Initiating regulatory procedures – what does the FDA look for? Initiating discussion with regulatory consultants √ Preparing succinct business plan for next investment round √ Creating a professional advisory board & appointing a medical director √ Initiating alliances with companies e.g. FP7 consortia √ Helping to secure follow-up financing / alliances with strategic partners
  • 12. Is project funding sufficient for required tasks? Weaknesses will the tight budget allow us to chose the “perfect” manager? How well do Government financing programs adapt to changing needs? Distance from global markets Support & coaching to company management Responsibility and accountability Strengths Focus on value creation - always market oriented Work-plan within a limited budget Achieving technological POC within these constraints Determination, flexibility & success orientation
  • 13. What do we need to do in order “to do better” ? Go Europe: create alliances Inclusion of our SMEs in FP7 consortia Participation of incubator in FP7 consortia Collaborations betw. our SMEs and clinical-centers /SMEs in other European bioregions Incubation of European pre-seed projects in RBM