The article provides background on career and technical education reform efforts in the US, focusing on the development of Programs of Study (POS). It discusses how POS aim to better integrate academic and career-focused education, drawing on initiatives like Tech Prep, career pathways, and dual enrollment. The reauthorization of the Perkins Act in 2006 required programs of study and aimed to make career pathways more coherent and rigorous. Three longitudinal studies of POS represented in this special issue are also introduced.