The document discusses the cardiovascular safety profile of various NSAIDs based on multiple clinical studies and meta-analyses. The key points are: 1. Naproxen has consistently shown a low or neutral cardiovascular risk compared to other NSAIDs like diclofenac, ibuprofen, coxibs. 2. Studies found diclofenac to be associated with higher risks of heart attack, stroke, and cardiovascular death than naproxen or paracetamol. 3. Guidelines from organizations like FDA, EMA and AHA recommend naproxen over diclofenac as the preferred NSAID due to its more favorable cardiovascular safety profile.