This document contains summaries of many common English proverbs and sayings, providing brief explanations of their meanings. Some of the proverbs explained include "A rolling stone gathers no moss", "A friend in need is a friend indeed", and "Tomorrow is another day". The document covers a wide range of topics related to work, relationships, opportunities, and more.
Clause (part 7 of 10)-Defining & Non-defining Relative clauseMd. Abdul Kader
By the end of the lesson you will be able to …
•define defining relative clauses.
•define non-defining relative clauses.
•explain punctuation rules with the defining and non-defining relative clause.
•mention the use of wh-words.
Clause (part 7 of 10)-Defining & Non-defining Relative clauseMd. Abdul Kader
By the end of the lesson you will be able to …
•define defining relative clauses.
•define non-defining relative clauses.
•explain punctuation rules with the defining and non-defining relative clause.
•mention the use of wh-words.
7 biggest mistakes people make during a de-clutter project by Helen Sanderson at Calm from Clutter -Ministry Of Calm
For more information, visit our website http://calmfromclutter.co.uk
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
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These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
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2. A rolling stone gathers no moss A person who never settles in one place or who often changes his job will not succeed in life ; one who is always changing his mind will never get anything done.
3. A friend in need is a friend indeed A friend who helps when one is in trouble is a real friend.
4. A burnt child dreads fire A bad experience or a horrifying incident may scar one's attitude or thinking for a lifetime.
5. Tomorrow is another day Things may improve tomorrow; tomorrow you will have a chance to solve the problems that are upsetting you today. (Often used to encourage someone to relax)
6. First come, first served The first in line will be attended to first.
7. Empty vessels make the most noise Those people who have a little knowledge usually talk the most and make the greatest fuss
8. Home is where the heart is People long to be at home.; Your home is whatever place you long to be. I've had a lovely time visiting you, but home is where the heart is, and I think it's time I went back.
9. A penny saved is a penny gained By being thrifty one will be able to save up.
10. Kill two birds with one stone. When you kill two birds with one stone, you resolve two difficulties or matters with a single action.
11. When the cat is away, the mice will play When no one in authority is present, the subordinates can do as they please. When the teacher left for a few minutes, the children nearly wrecked the classroom.
12. Barking dogs seldom bite Someone who makes threats all the time seldom carries out the threats.
13. Good walls make good neighbours Your relationship with your neighbours depends, among other things, on respecting one another's privacy.
14. Let sleeping dogs lie If someone is told to let sleeping dogs lie, it means that they shouldn't disturb a situation as it would result in trouble or complications.
15. There's no smoke without fire Something that you say which means that if people are saying that someone has done something bad but no one knows whether it is true, it probably is true
16. Turn over a new leaf. to begin again, fresh; to reform and begin again.
17. As you make your bed so must you lie on it. You must accept the consequences of your act.
18. Better late than never Better late than never means that it is better to do something late than to never do it at all. Example: "The movie has already started. Do you still want to go in?" Reply: "Sure. Better late than never !"
19. All's well when ends well An event that has a good ending is good even if some things went wrong along the way. (This is the name of a play by Shakespeare.)
20. Between the devil and the deep sea To choose between two equally bad alternatives in a serious dilemma.
21. Where there's a will there's a way When a person really wants to do something, he will find a way of doing it.
22. A hungry man is an angry man A person who does not get what he wants or needs is a frustrated person and will be easily provoked to rage.
23. Great talkers are little doers Those people who talk a lot and are always teaching others usually do not do much work.
24. An idle brain is the devil's workshop One who has nothing to do will be tempted to do many mischievous acts.
25. Faint heart never won fair lady To succeed in life one must have the courage to pursue what he wants.
26. Eat to live, but do not live to eat Man was created for a divine purpose and he has a destiny with his Creator - he was not born just to enjoy food
27. Don't put all your eggs in one basket One should not risk everything he has in a single venture
28. Every dog has its day Everyone will get a period of success or satisfaction during his lifetime.
29. Every one can find fault, few can do better It is easier to find fault in other people's actions or methods than to do it properly or correctly.
30. Any time means no time When an event is not decided on or planned earlier it will never take place.
31. Fire is a good servant but a bad master Fire, like any other manmade tool or device, will serve man well only when it is controlled and used wisely.
32. Fortune knocks once at every man's door Everyone gets at least one good opportunity in his lifetime; everyone has the opportunity to be successful in life
33. God helps those who help themselves God only helps those people who work hard and make an honest effort.
34. He laughs best who laughs last A person who does his best is the one who will get the greatest satisfaction in the end.
35. Never do things by halves One should not do an incomplete or imperfect job - certain tasks must not be left half done; they must be done away with immediately.
36. Great haste makes great waste If one does things hastily he will make a lot of mistakes - he will need to spend a lot of time correcting those mistakes later
37. It's no use crying over spilt milk It is pointless to feel remorseful over a thing lost that can never be found or a mistake done that can never be corrected or rectified.
38. Still waters run deep One who is usually silent and goes about his business quietly may be a very wise person.
39. Speech is silver, silence is golden Talk may be beneficial, but sometimes acquiescence may be the best option to take
40. Time and tide wait for no one Time is precious, once it is past no one can go back and claim it thus everyone should be mindful of how his time is spent.
41. No news is good news When there is no news, it is likely that everything is all right.
42. Look before you leap Avoid acting hastily, without considering the possible consequences.
43. Necessity is the mother of invention When a person is in great need of something, he will find a way of getting it.
44. Honesty is the best policy Being honest is believed to be the best route to take.
45. Two heads are better than one It is always better to get the view of another than to rely entirely on one's own judgment.
46. A bad workman always blames his tools A careless or unskilled worker blames bad work on his tools rather than himself.
47. A leopard cannot change its spots A person's nature cannot change
48. A new broom sweeps clean A person newly appointed is always eager and enthusiastic in his work.
49. Experience is the best teacher The best way to learn a job is to do it.
50. Half a loaf is better than none It's better to have or receive less than one desires than to have or receive nothing at all
51. A trouble shared is a trouble halved Your troubles seem half as great when you discuss them with someone else
52. Cut your coat according to your cloth Live within your income; don't be too ambitious in your plans
53. An apple a day keeps the doctor away It means that apples are so nutritious they keep you in the peak of health.
54. Two wrongs do not make a right If a person does something to harm or offend us, that's wrong. If we do something to harm them back, that's wrong too.