These slides contain the information about Estrogen, its basic pharmacology, its synthesis in human body, Functions of estrogen, role in female puberty, Agonists of estrogen and antagonists of estrogen, also contain detail of the receptors associated with the estrogen functioning.
These slides contain the information about Estrogen, its basic pharmacology, its synthesis in human body, Functions of estrogen, role in female puberty, Agonists of estrogen and antagonists of estrogen, also contain detail of the receptors associated with the estrogen functioning.
The two main sex hormones — estrogen and testosterone — have wide-ranging effects in the body. Produced primarily by the ovaries (estrogen) and testes (testosterone), these hormones affect not just your sexual function but also your bones, brain, and blood vessels.
Any of a group of potent hormone like substances that are produced in various mammalian tissues, are derived from arachidonic acid, and mediate a wide range of physiological functions, such as control of blood pressure, contraction of uterine, smooth muscle, and modulation of inflammation.
sex-hormones belong to the steroid class of compounds and are produced in the gonads, i.e., testes in the male and ovaries in the female. In fact, their activity seems to be controlled and monitored by the hormones that are produced in the interior.
The two main sex hormones — estrogen and testosterone — have wide-ranging effects in the body. Produced primarily by the ovaries (estrogen) and testes (testosterone), these hormones affect not just your sexual function but also your bones, brain, and blood vessels.
Any of a group of potent hormone like substances that are produced in various mammalian tissues, are derived from arachidonic acid, and mediate a wide range of physiological functions, such as control of blood pressure, contraction of uterine, smooth muscle, and modulation of inflammation.
sex-hormones belong to the steroid class of compounds and are produced in the gonads, i.e., testes in the male and ovaries in the female. In fact, their activity seems to be controlled and monitored by the hormones that are produced in the interior.
Progesterone Abnormalities up and down regulationArubSultan
Progesterone abnormalities refer to irregularities in the levels of the hormone progesterone, a crucial player in the female reproductive system. These imbalances can disrupt the menstrual cycle, leading to issues such as irregular periods, heavy bleeding, or amenorrhea. Inadequate progesterone levels may impact fertility, causing difficulty in conceiving or maintaining a pregnancy. Conversely, excess progesterone can result in symptoms like fatigue, mood swings, and breast tenderness. Progesterone abnormalities is essential for maintaining reproductive health and hormonal balance in both men and women. In men, imbalances in progesterone levels may impact libido, mood, and energy levels. Treatment for progesterone abnormalities typically involves hormone replacement therapy (HRT) to restore balance. In cases of low progesterone, supplemental progesterone medications, such as oral capsules or creams, may be prescribed. Lifestyle modifications, such as stress management and a healthy diet, can also positively impact progesterone levels.
Role of progestogens in obstetrics and gynecologyAhmad Saber
The
different progestogens with their overlapping effects on estrogen, androgen, glucocorticoid,
and mineralocorticoid receptors are described in order to allow the clinician to make the most appropriate choice of progestogen.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
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Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
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Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
2. Progesterone
oProgesterone is an endogenous steroid hormone involved in
menstrual cycle ,pregnancy & embryogenesis of humans.
oProgesterone is also important metabolic intermediate in the
production of other endogenous steroids.
oplays an important role in brain function as a neurosteroid.
Formed in:
• CORPUS LEUTEUM:in the early pregnancy .
• PLACENTA:in the late pregnancy period.
• TESTES
• ADRENAL CORTEX
4. Distribution And receptors
Progesterone binding is
distributed as follows:
1) Approximately 18% of serum
progesterone is bound to
transcortin(corticosteroid-
binding globulin (CBG)
2) the another 80% of it is
bound to serum albumin.
3) The remaining 2% is free
PR is expressed in the following organs:
1-central nervous system (CNS) 2- Endocrine
3-gastrointestinal 4-immune 5-reproductive 6-
cardiovascular 7-respiratory
5.
6. Physiological and metabolic effect.
Physiological:
1. prepares the endometrium pregnancy
2. It triggers the lining to thicken to
accept a fertilized egg
3. prohibits the muscle contractions in
the uterus
4. If no fertilization occurs the corpus
luteum breaks down, lowering the
progesterone levels in the body.
5. During the 7-10 week of pregnancy, the
placenta begins to secrete
progesterone.supporting the corpus
luteum.
6. It also helps prepare the breasts for
milk production.
Metabolic:
1. important effects on carbohydrate,
lipid and protein metabolism.
2. promoting glycogen storage in the liver
3. antagonizes the effects of insulin on
glucose metabolism in adipose tissue
4. stimulates deposition of body
7. Normal values of progesterone hormone
Normal values of progesterone hormone for non - pregnant women Average
monthly days 28 days
Days from 1 - 6 Less than 100 ng/dL Less than 1 ng/mL
Days from 7 - 14 20 – 150 ng/dL 0.2 – 1.5 ng/mL
Days from 15 - 28 250 – 2800 ng/dL 2 – 28 ng/mL
Normal values of progesterone in pregnancy
first third 900 – 4700 ng/dL 9 – 47 ng/mL
second third 1700 – 14700 ng/dL 17 – 147 ng/mL
The last third 5500 – 20000 ng/dL 55 – 200 ng/mL
Normal values of progesterone hormone after menopause
Less than 40 ng/dL Less than 1ng/mL
8. Low Progesterone levels
Symptoms of low
Progesterone Levels
Menstrual irregularities.
Fibrocystic breasts:usually
noncancerous.
Difficulty Getting Pregnant.
Difficulty Staying Pregnant.
Anxiety.
low progesterone levels can
be caused by:
Untreated Hypothyroidism
Adequate thyroid hormone and
function is required for both
regular ovulation and
progesterone production in the
body
Age around age 35
progesterone levels will start to
drop until menopause
Menopause
9. High Progesterone Levels
Symptoms of High
Progesterone Levels
Anxiety
Bloating
Urinary infections
Loss of libido
Weight gain
high progesterone levels can
be caused by:
ovarian cancer
adrenal cancer
congenital adrenal
hyperplasia