Multi-Relational Graph Structures: From Algebra to ApplicationMarko Rodriguez
In a single-relational graph, all edges share the same meaning. In contrast, a multi-relational graph represents a heterogeneous set of edges, where each edge is labeled to denote the type of relationship that exists between the two vertices it connects. While less prevalent than the single-relational graph, the multi-relational graph structure is beginning to see widespread adoption in both academia and industry. An algebra for manipulating multi-relational graph structures and the realization of this algebra in various application scenarios is presented in this talk.
Experience Design: Why Pages Are The Last Thing You Need To Worry Abouttim richards
Annotations/Backstory available on my blog: http://www.exfoo.com/2009/03/emerging-experience-design-tenets/
Some thoughts on emerging approaches to designing experiences; major differences between traditional "IA" or "desktop publishing" and designing user experiences.
How many of us really know the usage, importance and need of cloud computing? Good question isn’t it? Yes, the meaning is simple, it’s like the passing clouds in the sky, consider the moon as a software and users as clouds. Clouds pass over the moon and every cloud gets its chance to completely or partially cover the moon, isn’t it? So, this is the basic concept, if understood the assumptions. Accessing the timekeeping software’s partially or completely which is on a particular server is called cloud computing.
DRYCAKE has been in the separation process globally for 20+ years and has a complete range of products in several industrial applications. Technology provider for liquid & solid waste reuse and recovery.
They include quality drying, dewatering, screening, thickening, and materials handling for industrial and municipal markets.
DRYCAKE’s solutions are among the most innovative technologies around the world.
DRYCAKE is here to meaningfully contribute to our planet. Our process packages contribute to a better environment. Our process packages recover clarified liquids and dry solids from process streams. We reduce the charge to our landfills, produce bio-energy and increase the water available to the environment.
Летом самые низкие цены на новогоднюю продукцию из Китая. Заказав сейчас Вы получите товары по ценам дешевле рыночных от 20-300% даже с учетом доставки из Китая.
Multi-Relational Graph Structures: From Algebra to ApplicationMarko Rodriguez
In a single-relational graph, all edges share the same meaning. In contrast, a multi-relational graph represents a heterogeneous set of edges, where each edge is labeled to denote the type of relationship that exists between the two vertices it connects. While less prevalent than the single-relational graph, the multi-relational graph structure is beginning to see widespread adoption in both academia and industry. An algebra for manipulating multi-relational graph structures and the realization of this algebra in various application scenarios is presented in this talk.
Experience Design: Why Pages Are The Last Thing You Need To Worry Abouttim richards
Annotations/Backstory available on my blog: http://www.exfoo.com/2009/03/emerging-experience-design-tenets/
Some thoughts on emerging approaches to designing experiences; major differences between traditional "IA" or "desktop publishing" and designing user experiences.
How many of us really know the usage, importance and need of cloud computing? Good question isn’t it? Yes, the meaning is simple, it’s like the passing clouds in the sky, consider the moon as a software and users as clouds. Clouds pass over the moon and every cloud gets its chance to completely or partially cover the moon, isn’t it? So, this is the basic concept, if understood the assumptions. Accessing the timekeeping software’s partially or completely which is on a particular server is called cloud computing.
DRYCAKE has been in the separation process globally for 20+ years and has a complete range of products in several industrial applications. Technology provider for liquid & solid waste reuse and recovery.
They include quality drying, dewatering, screening, thickening, and materials handling for industrial and municipal markets.
DRYCAKE’s solutions are among the most innovative technologies around the world.
DRYCAKE is here to meaningfully contribute to our planet. Our process packages contribute to a better environment. Our process packages recover clarified liquids and dry solids from process streams. We reduce the charge to our landfills, produce bio-energy and increase the water available to the environment.
Летом самые низкие цены на новогоднюю продукцию из Китая. Заказав сейчас Вы получите товары по ценам дешевле рыночных от 20-300% даже с учетом доставки из Китая.
The design of chemical libraries is usually informed by pre-existing characteristics and desired features. On the other hand, assesing the prospective performance of a new library is more difficult. Importantly, a given screening library is often screened in a variety of systems which can differ in cell lines, readouts, formats and so on. In this study we explore to what extent pre-existing libraries can shed light on the relation between library activity and assay features. Using an ontology such as the BAO, it is possible to construct a hierarchy of annotations associated with an assay. Based on this annotation hierarchy we can then ask how likely are molecules associated with a specific annotation, to be identified as active. To allow generalization we consider substrucural features, as represented by a structural key fingerprint, rather than whole molecules. We employ a Bayesian framework to quantify the the association between a substructural feature and a given assay annotation, using a set of NCGC assays that have been annotated with BAO terms. We discuss our approach to training the Bayesian model and describe benchmarks that characterize model performance relative to the position of the annotation in the BAO hierarchy. Finally we discuss the role of this approach in a library design workflow that includes traditional design features such as chemical space coverage and physicochemical properties but also takes in to account screening platform features.
263778731218 Abortion Clinic /Pills In Harare ,sisternakatoto
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micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Prioritizing Scaffolds for Hit Selection in High Throughput Screening Programs
1. Priori%zing Scaffolds for Hit Selec%on
in High Throughput Screening
Programs
Rajarshi Guha, Dac‐Trung Nguyen
NIH Chemical Genomics Center
6th Indo‐US Workshop on Mathema%cal Chemistry
8th – 10th January, 2010
3. NIH Chemical Genomics Center
Assay development Compound
and op2miza2on Op2miza2on
Small Molecules
Biology Chemistry
NCGC
Informa%cs ACOM
Genome wide RNAi
SAR analysis, method & Automa2on, Compound
tool development management
4. High Throughput Screening
• Assay thousands to
hundreds of thousands
of compounds
– Biochemical, gene%c,
pharmacological assays
• Rapidly iden%fy novel
modulators of biological
systems
• Lots of raw data –
automated analy%cs are
essen%al
5. Hun%ng for Leads
Target Lead Lead Clinical
Iden%fica%on Discovery Op%miza%on Development
HTS
Primary
Confirma%on
• Sensi%vity Screening • Select subset
• Scaling • Fluorescence to follow up • Counter
• High Content • Diversity screen
• Explore SAR
Assay
Cherry Picking
Op%miza%on