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Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
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2. • The AP pelvis view is part of a pelvic series examining the
iliac crest, sacrum, proximal femur, pubis, ischium.
• Indication : Trauma, Dis location.
• Patient position
• patient is supine.
• lower limbs are internally rotated 15-25° from the hip (do not
attempt this if a fracture is suspected) to demonstrate an AP
view of the proximal femur
3. • centering point
• the midpoint of the anterior superior iliac spine and the pubic symphysis
• collimation
• laterally to the skin margins
• superior to above the iliac crests
• inferior to the proximal femur
SID : 100 cm
• Grid : yes
• Cassette : 14×17 inch
4.
5.
6. • Posterior oblique
• The patient lies supine on the X-ray table, legs extended
• The patient rotates through 45° onto the affected side with
the hip abducted 45° and flexed 45°
• The knee is flexed to bring the lateral aspect of the thigh in
contact with the tabletop and the knee rests on the table in
the lateral position.
7.
8. frog’s legs position
• When comparison of both hips is required.
• This may apply in children.
• The patient lies supine on the X-ray table with the anterior superior
iliac spines equidistant from the tabletop to avoid rotation of the
pelvis.
• The hips and knees are flexed and both limbs rotated laterally
through approximately 60°.
9.
10. Judet’s’ projection
• This projection may be used to assess the acetabulum when a
fracture is suspected.
• Anterior oblique
• The patient lies prone on the X-ray table .
• The trunk is then rotated approximately 45º onto the UNAFFECTED
SIDE.
• In this position the rim of the acetabulum nearest the tabletop
• .
11.
12. Reverse Judet’s
• The patient lies supine on the X-ray table.
• The AFFECTED SIDE is raised approximately 45º