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Combined of HVLA manipulation, exercise and physical therapy for treatment of Lateral
multimodal therapies for chronic tennis elbow: pilot study
Combination
to test protocols for a randomized clinical trials
epicondylitis
1,
Radpasand

Over View

Lateral epicondylitis, also known as tennis elbow is
defined as pain over the lateral aspect of the elbow
which is aggravated by active wrist extension and
direct palpation over either the lateral epicondyle of
the humerus, the radio-humeral joint space or the
proximal muscle bellies. The incidence and
prevalence is approximately 1%-3%. Women are
more often affected than men, of 9% and 3%
respectively, with a peak prevalence at age 42-44.
At least 40 different treatment modalities aiming to
reduce pain and increase function have been
described, but the optimal treatment remains
undefined.

Hard-padded elbow brace knob was placed
exactly on top of the most painful area

4. Ice: Small amount, just to cover the
lateral epicondyle
5. Exercises (4 Types): Isometric end
point contraction

Exercise
A) Forearm Extensor
Muscle

Objective

Has two parts 1) pure extension
at the wrist, 2) radial deviation
and extension

To develop and test protocols for a randomized
clinical trial (RCT) of 2 multimodal package therapies
for chronic lateral epicondylitis (CLE).

B) Forearm Flexor
Muscle

Methods
Six participants were enrolled after case review
and randomized to 1 of 2 groups (4 in group A
and 2 in group B) for 12 weeks of treatment.
Group A: high-velocity-low-amplitude
manipulation (HVLA), high-voltage pulse
galvanic stimulation (HVPGS), counterforce
bracing, ice, and exercise.
Group B: ultrasound, counterforce bracing,
and exercise. Both groups had suggestion to
restrict usage of the affected elbow.
All participants were asked to complete a visual
analog scale questionnaire (VAS_24hs) and a
patient-rated tennis elbow evaluation (PRTEE)
every week. Pain-free grip strength (PFGS) was
measured at baseline, and at Weeks 3, 6,9,and
12.

Multimodal package A

Multimodal package A
1. Manipulation - HVLA Type
A quick thrust using the pad of the thumb in a posterior to
anterior direction over the posterior aspect of the radial
head, approximately on top of the extensor tendon
attachment to the lateral epicondyle. The patient sat on a
chair with the upper body in postural alignment. The
provider’s opposite hand holds the dorsum of the
patient’s wrist. The provider starts with the elbow slightly
flexed, takes it to full extension and applies the thrust at
the end-range while extending the elbow and pronating
the forearm

2. High-voltage pulse galvanic stimulation
(HVPGS): 150 Hz ; 19-29mA
Positive pad was over the lateral epicondyle
Negative pad was at the base of involved elbow’s
scapula

3. Hard-padded elbow brace

Has two parts 1) pure flexion
at the wrist, 2) radial
deviation, and flexion

Multimodal package B
1.

2.
3.

Ultrasound
Time: set at 8 minutes
Dosage: 3 MHz, 1.5 W/cm²
Pulse mode: 20%
Transducer head area: 2 cm²
Hard-padded elbow brace
Exercises (1Type ): Isometric end point contraction
 Putty therapeutic

Result
One participant in group A dropped out before the end of care.
Both groups demonstrated changes in all of the outcome
variables from baseline to the endpoint of treatment. In group A,
there was a 59% change for PRTEE total, a 3.2% change for
PFGS, and a 51.4% change for VAS_24hs worst pain felt
compared to 9.5%, 169.0%, and 65.1%, respectively, for group
B. The painful elbow showed less strength than the non-painful
one, and there was an inverse relationship between PRTEE
and PFGS. The sample size for a larger RCT calculated post
ad hoc was 246 participants.
Pain Free Grip Strength

Patient-Rated Tennis Elbow Evaluation

VAS 24hs Worst Pain
Group A

70

90

60

50

80

50

C) Exercise for Supinator and
Pronator Muscle

40

70

40
30
20
10

D) Putty Therapeutic
The arm and forearm should make a 90° angle
with each other, with the wrist extended as far as
it can, while holding the putty. The putty will be
pushed toward the thenar surface of the palm of
the hand by flexing the four digits of 2 to 5 as
hard as possible.

30
20

10
0

Pre

-20

Time Point

40

20

Post

Post

-10

50

0
-10

Pre

60

30

10

Pre

0

The participant has the full active
control of the weight. The elbow is
supported at the edge of the table,
while the arm and forearm make a 90°
angle. All of the exercises had duration
per repetition of 10s, with 10
repetitions maximum.

Group A
Group B

100

Group A
Group B

60

Group B

Kilograms

Background

2 Northwestern Health Sciences University, Bloomington, MN
Department, D’Youville College, Buffalo, NY
Palmer Center for Chiropractic Research, Davenport, IA, USA

PRTEE Score (0-50)

1Chiropractic

VAS (0-100)

1

Mohsen
E.F. Owens
Mohsen Radpasand, DC, MD Jr

2

Time Point

Post
Time Point

Conclusions: This pilot study demonstrated that the study
design is feasible and that patients could be recruited for a 12week trial of multimodal treatment. A larger, multicenter trial is
warranted to evaluate these treatment strategies.
Disclosure: Supported by a grant from the NIH (K30-AT-0097704). This study was conducted at the Palmer Center for
Chiropractic Research (PCCR), which was constructed with
support of a Research Facilities Improvement Grant
(C06RR15433) from the National Center for Research Resources
at the NIH. The NCMIC provided financial support for the program,
and the Chattanooga Group provided the ultrasound unit for this
study. J Manipulative Physiol Ther. 2009;32(7):571-585

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American Academy of Pain Management-September 2010

  • 1. Combined of HVLA manipulation, exercise and physical therapy for treatment of Lateral multimodal therapies for chronic tennis elbow: pilot study Combination to test protocols for a randomized clinical trials epicondylitis 1, Radpasand Over View Lateral epicondylitis, also known as tennis elbow is defined as pain over the lateral aspect of the elbow which is aggravated by active wrist extension and direct palpation over either the lateral epicondyle of the humerus, the radio-humeral joint space or the proximal muscle bellies. The incidence and prevalence is approximately 1%-3%. Women are more often affected than men, of 9% and 3% respectively, with a peak prevalence at age 42-44. At least 40 different treatment modalities aiming to reduce pain and increase function have been described, but the optimal treatment remains undefined. Hard-padded elbow brace knob was placed exactly on top of the most painful area 4. Ice: Small amount, just to cover the lateral epicondyle 5. Exercises (4 Types): Isometric end point contraction Exercise A) Forearm Extensor Muscle Objective Has two parts 1) pure extension at the wrist, 2) radial deviation and extension To develop and test protocols for a randomized clinical trial (RCT) of 2 multimodal package therapies for chronic lateral epicondylitis (CLE). B) Forearm Flexor Muscle Methods Six participants were enrolled after case review and randomized to 1 of 2 groups (4 in group A and 2 in group B) for 12 weeks of treatment. Group A: high-velocity-low-amplitude manipulation (HVLA), high-voltage pulse galvanic stimulation (HVPGS), counterforce bracing, ice, and exercise. Group B: ultrasound, counterforce bracing, and exercise. Both groups had suggestion to restrict usage of the affected elbow. All participants were asked to complete a visual analog scale questionnaire (VAS_24hs) and a patient-rated tennis elbow evaluation (PRTEE) every week. Pain-free grip strength (PFGS) was measured at baseline, and at Weeks 3, 6,9,and 12. Multimodal package A Multimodal package A 1. Manipulation - HVLA Type A quick thrust using the pad of the thumb in a posterior to anterior direction over the posterior aspect of the radial head, approximately on top of the extensor tendon attachment to the lateral epicondyle. The patient sat on a chair with the upper body in postural alignment. The provider’s opposite hand holds the dorsum of the patient’s wrist. The provider starts with the elbow slightly flexed, takes it to full extension and applies the thrust at the end-range while extending the elbow and pronating the forearm 2. High-voltage pulse galvanic stimulation (HVPGS): 150 Hz ; 19-29mA Positive pad was over the lateral epicondyle Negative pad was at the base of involved elbow’s scapula 3. Hard-padded elbow brace Has two parts 1) pure flexion at the wrist, 2) radial deviation, and flexion Multimodal package B 1. 2. 3. Ultrasound Time: set at 8 minutes Dosage: 3 MHz, 1.5 W/cm² Pulse mode: 20% Transducer head area: 2 cm² Hard-padded elbow brace Exercises (1Type ): Isometric end point contraction  Putty therapeutic Result One participant in group A dropped out before the end of care. Both groups demonstrated changes in all of the outcome variables from baseline to the endpoint of treatment. In group A, there was a 59% change for PRTEE total, a 3.2% change for PFGS, and a 51.4% change for VAS_24hs worst pain felt compared to 9.5%, 169.0%, and 65.1%, respectively, for group B. The painful elbow showed less strength than the non-painful one, and there was an inverse relationship between PRTEE and PFGS. The sample size for a larger RCT calculated post ad hoc was 246 participants. Pain Free Grip Strength Patient-Rated Tennis Elbow Evaluation VAS 24hs Worst Pain Group A 70 90 60 50 80 50 C) Exercise for Supinator and Pronator Muscle 40 70 40 30 20 10 D) Putty Therapeutic The arm and forearm should make a 90° angle with each other, with the wrist extended as far as it can, while holding the putty. The putty will be pushed toward the thenar surface of the palm of the hand by flexing the four digits of 2 to 5 as hard as possible. 30 20 10 0 Pre -20 Time Point 40 20 Post Post -10 50 0 -10 Pre 60 30 10 Pre 0 The participant has the full active control of the weight. The elbow is supported at the edge of the table, while the arm and forearm make a 90° angle. All of the exercises had duration per repetition of 10s, with 10 repetitions maximum. Group A Group B 100 Group A Group B 60 Group B Kilograms Background 2 Northwestern Health Sciences University, Bloomington, MN Department, D’Youville College, Buffalo, NY Palmer Center for Chiropractic Research, Davenport, IA, USA PRTEE Score (0-50) 1Chiropractic VAS (0-100) 1 Mohsen E.F. Owens Mohsen Radpasand, DC, MD Jr 2 Time Point Post Time Point Conclusions: This pilot study demonstrated that the study design is feasible and that patients could be recruited for a 12week trial of multimodal treatment. A larger, multicenter trial is warranted to evaluate these treatment strategies. Disclosure: Supported by a grant from the NIH (K30-AT-0097704). This study was conducted at the Palmer Center for Chiropractic Research (PCCR), which was constructed with support of a Research Facilities Improvement Grant (C06RR15433) from the National Center for Research Resources at the NIH. The NCMIC provided financial support for the program, and the Chattanooga Group provided the ultrasound unit for this study. J Manipulative Physiol Ther. 2009;32(7):571-585