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• Classified as an anxiety disorder.
• After trauma exposes the victim to actual or threatened
death or serious injury, 3 dimensions of PTSD unfold:
(1) reexperiencing the event with distressing
recollections, dreams, flashbacks, and/or psychologic
and physical distress;
(2) persistent avoidance of stimuli that might invite
memories or experiences of the trauma; and
(3) increased arousal
(Vieweg et al, 2006)
Post traumatic stress
disorder
1
Post traumatic stress
disorder
2
• Research into the pathophysiology of PTSD has
focussed on areas of the brain associated with
fear processing and memory:
- Amygdala, Hippocampus, Medial prefrontal
cortex
• There is still uncertainty over the patho-
physiology of PTSD.
• Hypothesised that PTSD represents a failure of
the prefrontal-anterior networks to regulate the
amygdala – resulting in hyper-reactivity to
threat.
Pathophysiology of PTSD
3
• Where would you see the physiotherapists role
in helping people with PTSD?
QUESTION
4
1) genetic factors and gene by environment
interactions;
2) developmental/childhood factors;
3) neurobiological risk and resilience factors;
4) psychological risk and resilience factors (e.g.,
coping style, personality);
5) cognitive/behavioral risk and resilience factors
(e.g., processing information and appraisal of
information);
6) social factors.
Pathophysiology – only one
part of the picture
5
Through this session you have:
• Considered and practically utilised relevant
outcome measures to identify common mental
health conditions.
• Gained a brief overview of the pathophysiology
of common mental health conditions.
• Discussed the practical application of this
knowledge to physiotherapy practice.
• Considered other influences on individuals
mental and emotional health.
Overview
6
Vieweg WV, Julius DA, Fernandez A, Beatty-Brooks M, Hettema JM,
Pandurangi AK. (2006) Posttraumatic stress disorder: clinical features,
pathophysiology, and treatment, American Journal of Medicine, 119 , 5,
383-390.
Hasler, G. (2010) Pathophysiology of depression: do we have any solid
evidence of interest to clinicians?. World Psychiatry, 9, 3, 155–161.
NIMH (2013) Signs and symptoms of depression, accessed 18/02/2013 @
11.30 am http://www.nimh.nih.gov/health/publications/depression/what-are-
the-signs-and-symptoms-of-depression.shtml
CNS Forum accessed 18/02/2013 @ 10:00am http://www.cnsforum.com/
References
7

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Post traumatic stress disorder

  • 1. • Classified as an anxiety disorder. • After trauma exposes the victim to actual or threatened death or serious injury, 3 dimensions of PTSD unfold: (1) reexperiencing the event with distressing recollections, dreams, flashbacks, and/or psychologic and physical distress; (2) persistent avoidance of stimuli that might invite memories or experiences of the trauma; and (3) increased arousal (Vieweg et al, 2006) Post traumatic stress disorder 1
  • 3. • Research into the pathophysiology of PTSD has focussed on areas of the brain associated with fear processing and memory: - Amygdala, Hippocampus, Medial prefrontal cortex • There is still uncertainty over the patho- physiology of PTSD. • Hypothesised that PTSD represents a failure of the prefrontal-anterior networks to regulate the amygdala – resulting in hyper-reactivity to threat. Pathophysiology of PTSD 3
  • 4. • Where would you see the physiotherapists role in helping people with PTSD? QUESTION 4
  • 5. 1) genetic factors and gene by environment interactions; 2) developmental/childhood factors; 3) neurobiological risk and resilience factors; 4) psychological risk and resilience factors (e.g., coping style, personality); 5) cognitive/behavioral risk and resilience factors (e.g., processing information and appraisal of information); 6) social factors. Pathophysiology – only one part of the picture 5
  • 6. Through this session you have: • Considered and practically utilised relevant outcome measures to identify common mental health conditions. • Gained a brief overview of the pathophysiology of common mental health conditions. • Discussed the practical application of this knowledge to physiotherapy practice. • Considered other influences on individuals mental and emotional health. Overview 6
  • 7. Vieweg WV, Julius DA, Fernandez A, Beatty-Brooks M, Hettema JM, Pandurangi AK. (2006) Posttraumatic stress disorder: clinical features, pathophysiology, and treatment, American Journal of Medicine, 119 , 5, 383-390. Hasler, G. (2010) Pathophysiology of depression: do we have any solid evidence of interest to clinicians?. World Psychiatry, 9, 3, 155–161. NIMH (2013) Signs and symptoms of depression, accessed 18/02/2013 @ 11.30 am http://www.nimh.nih.gov/health/publications/depression/what-are- the-signs-and-symptoms-of-depression.shtml CNS Forum accessed 18/02/2013 @ 10:00am http://www.cnsforum.com/ References 7