Popliteal Artery Entrapment Syndrome (PAES) is a rare pathological compression of the popliteal artery, mostly unilateral. Its diagnosis is a challenge due to low recurrence and confusion with other
injuries that affect the lower limb. Delay in its repair can cause
arterial stenosis, emboli, aneurysm, inability to perform physical
activities, thromboembolism and acute limb ischemia. Young men
without comorbidities who may exercise regularly with intermittent claudication that affects their daily activities should draw attention to research and treatment of the syndrome. Investigation
is extremely important to rule out differential diagnoses, such as
chronic compartment syndrome, neurogenic claudication, peripheral atherosclerosis and cystic disease of the popliteal artery.
Surgical Management of Lower Limb Occlusive Arterial Diseaserajendra meena
This slide explains briefly touches upon Occlusive Arterial Disease (Peripheral Arterial Disease (PAD)) in the lower limbs along with the types, classification, diagnostic evaluation and various management protocols.
PAD can be diagnosed in asymptomatic individuals by a combination of physical examination and simple, noninvasive Doppler ultrasonography to measure the ankle–brachial index
Surgical Management of Lower Limb Occlusive Arterial Diseaserajendra meena
This slide explains briefly touches upon Occlusive Arterial Disease (Peripheral Arterial Disease (PAD)) in the lower limbs along with the types, classification, diagnostic evaluation and various management protocols.
PAD can be diagnosed in asymptomatic individuals by a combination of physical examination and simple, noninvasive Doppler ultrasonography to measure the ankle–brachial index
Introduction: There is growing evidence that Obstructive Sleep Apnea (OSA) is a risk factor for Pulmonary Embolism (PE). This
association represents a major public health burden.Aims and Objectives: To investigate Computed Tomography Obstruction Index (CTOI) and the Right Ventricular (RV) to Left Ventricular (LV) diameter ratio with OSA severity. Materials and Methods: 46 Patients with (PE) were evaluated for OSA. Pulmonary Artery Obstruction Index (PAOI) and RV/ LV diameter ratio was measured by pulmonary angiography. Pulmonary Embolism Severity Index (PESI) was determined. Epworth Sleepiness Scale (ESS) and Polysomnography (PSG) was performed for all patients. Based on the PAOI, patients divided into (< 15%, 15-50%, > 50%).
The Vertebral Artery Test
Luc Peeters, MSc.Ost. & Grégoire Lason, MSc.Ost.
The International Academy of Osteopathy
http://www.osteopathie.eu/en
http://www.osteopathie.eu/en/publications
info@osteopathy.eu
—VACTERL / VATER association is defined by the presence of at least three of the following congenital malformations: vertebral defects, anal atresia, cardiac defects, trachea-esophageal fistula, renal anomalies and limb abnormalities. It is diagnosed clinically by the above features with presence of core component features like trachea-esophageal fistula or ano-rectal malformations. Etiology is largely unknown. Management centers on surgical correction of the specific congenital malformations in the immediate postnatal period followed by long term treatment of the sequelae. Prognosis is good if surgical correction is achieved but majority continue to be affected by their malformations throughout life.
Despite the advances in diagnostic methods and techniques for surgical treatment in the last two decades, aortic diseases remain a major cause of mortality and cardiovascular morbidity, challenging physicians and molecular biologists. It is believed that about 600 million years ago, during the Cambrian period, variant forms of life appeared, among them were the oxygen-producing cyano bacteria.
12-lead electrocardiogram features of arrhythmic risk: A focus on early repolarization
Caterina Rizzo, Francesco Monitillo, Massimo Iacoviello
Caterina Rizzo, Francesco Monitillo, School of Cardiology, Department of Emergency and Organ Transplantation, University of Bari, 70124 Bari, Italy
Massimo Iacoviello, Cardiology Unit, Department of Cardiothoracic, Policlinic University Hospital, 70124 Bari, Italy
When and Where? Hybrid Procedure after Percutaneous Coronary Interventionsemualkaira
Invasive angiography in high risk of significant disease is class A of recommendation. Myocardial infarction caused by dissection of
coronary artery is very rare complication. The infarct-related artery (IRA) should be treated during the initial intervention. If PCI of the
IRA cannot by performed coronary artery bypass (CABG) should be considered.
Incidence of VTE in the First Postoperative 24 Hours after Abdominopelvic Sur...semualkaira
A good number of research reports the incidence of postoperative venous thromboembolism (VTE) mostly
looks at longer postoperative duration, usually days after surgery.
1.2. Objective: We investigated the incidence of early asymptomatic VTE (24 hours postoperatively) to assess the relevance of generalisation of extended post-hospital discharge chemoprophylaxis
Introduction: There is growing evidence that Obstructive Sleep Apnea (OSA) is a risk factor for Pulmonary Embolism (PE). This
association represents a major public health burden.Aims and Objectives: To investigate Computed Tomography Obstruction Index (CTOI) and the Right Ventricular (RV) to Left Ventricular (LV) diameter ratio with OSA severity. Materials and Methods: 46 Patients with (PE) were evaluated for OSA. Pulmonary Artery Obstruction Index (PAOI) and RV/ LV diameter ratio was measured by pulmonary angiography. Pulmonary Embolism Severity Index (PESI) was determined. Epworth Sleepiness Scale (ESS) and Polysomnography (PSG) was performed for all patients. Based on the PAOI, patients divided into (< 15%, 15-50%, > 50%).
The Vertebral Artery Test
Luc Peeters, MSc.Ost. & Grégoire Lason, MSc.Ost.
The International Academy of Osteopathy
http://www.osteopathie.eu/en
http://www.osteopathie.eu/en/publications
info@osteopathy.eu
—VACTERL / VATER association is defined by the presence of at least three of the following congenital malformations: vertebral defects, anal atresia, cardiac defects, trachea-esophageal fistula, renal anomalies and limb abnormalities. It is diagnosed clinically by the above features with presence of core component features like trachea-esophageal fistula or ano-rectal malformations. Etiology is largely unknown. Management centers on surgical correction of the specific congenital malformations in the immediate postnatal period followed by long term treatment of the sequelae. Prognosis is good if surgical correction is achieved but majority continue to be affected by their malformations throughout life.
Despite the advances in diagnostic methods and techniques for surgical treatment in the last two decades, aortic diseases remain a major cause of mortality and cardiovascular morbidity, challenging physicians and molecular biologists. It is believed that about 600 million years ago, during the Cambrian period, variant forms of life appeared, among them were the oxygen-producing cyano bacteria.
12-lead electrocardiogram features of arrhythmic risk: A focus on early repolarization
Caterina Rizzo, Francesco Monitillo, Massimo Iacoviello
Caterina Rizzo, Francesco Monitillo, School of Cardiology, Department of Emergency and Organ Transplantation, University of Bari, 70124 Bari, Italy
Massimo Iacoviello, Cardiology Unit, Department of Cardiothoracic, Policlinic University Hospital, 70124 Bari, Italy
When and Where? Hybrid Procedure after Percutaneous Coronary Interventionsemualkaira
Invasive angiography in high risk of significant disease is class A of recommendation. Myocardial infarction caused by dissection of
coronary artery is very rare complication. The infarct-related artery (IRA) should be treated during the initial intervention. If PCI of the
IRA cannot by performed coronary artery bypass (CABG) should be considered.
Incidence of VTE in the First Postoperative 24 Hours after Abdominopelvic Sur...semualkaira
A good number of research reports the incidence of postoperative venous thromboembolism (VTE) mostly
looks at longer postoperative duration, usually days after surgery.
1.2. Objective: We investigated the incidence of early asymptomatic VTE (24 hours postoperatively) to assess the relevance of generalisation of extended post-hospital discharge chemoprophylaxis
Analyses of Risk Factors of Diarrhea in Patients with Esophagectomysemualkaira
Esophageal cancer is one of the most common
cancers of the world and surgery is an effective treatment for that.
However, long-term complications, such as diarrhea, are the focus
on the postoperative quality of life. Until now, the etiologies of
diarrhea after esophagectomy are still ill-defined
Protective Effect of Essential Oil of Pelargonium Graveolens against Paraceta...semualkaira
Pelargonium graveolens is an aromatic and medicinal plant, belonging to the Geraniaceae family that grows in temperate areas of
the world, which characterized by its therapeutic proprieties. It is
widely known as one of the medicinal herbs with the highest antioxidant activity. T
Axonal Polyneuropathy with Anti-Caspr1 Igg1 Paranodal Antibodiessemualkaira
The main electrophysiological manifestation of
autoimmune paranodopathy with anti-contactin-associated protein
1 (Caspr1) positive reported previously was demyelination, with
or without axonal involvement. Here, we reported a patient with
anti-Caspr1 IgG1 positive who had severe axonal involvement accompanied less evidence of demyelination.
Laryngeal Lesion of Epidermolysis Bullosa: Topical Use of Mitomycin-Csemualkaira
Epidermolysis bullosa (EB) is a mucocutaneous genetic disease
characterized by fragility of the dermoepidermal junction. Laryngeal lesions frequently occur in junctional epidermolysis bullosa
(JEB), a subtype of EB.
The Efficacy and Safety of Convalescent Plasma for COVID-19 Patients: A Meta-...semualkaira
Convalescent plasma (CP) was demonstrated
promising benefit for clinical practice involved in efficacy and
safety in previous coronavirus pandemics, however, the efficacy of
CP from COVID-19 sufferers are still controversial and unascertainable based on current randomized controlled trials (RCTs). The
urgent needs for affirmative replies on the efficacy and safety of
CP for COVID-19 patients must be developed as soon as possible.
Borderline Ovarian Tumors – Diagnostic and Treatment Modalitiessemualkaira
Ovarian tumors occur in one third of all women gynecology organs. Out of that borderline ovarian tumors occur in 10 – 15% out
of all ovarian tumors. They are tumors with low malignant potential, which are different from benign lesions and malignancies by
its’ biological behavior and by histological structure
The human microbiota is an extremely large system with its majority inhabitin...semualkaira
Human microbiota is the system englobing more than 100 trillion
microorganisms living in symbiosis with the hosting body [1, 2].
The majority of the human microbiota inhabits the gastrointestinal
tract especially the colon
COVID-19 Infection Occurring in The Postoperative Period in A Patient Who Und...semualkaira
While the coronavirus-associated Covid-19 infection remains a
risk for people all over the world as a pandemic, it is also a major
catastrophic clinical situation for patients undergoing surgery in
hospitals. If patients encounter this infection picture, especially
after severe operations such as heart surgery, the life-threatening
rates increase gradually.
Incisional Hernia Occurring after Ventriculoperitoneal Shunt Fixationsemualkaira
Ventriculo-peritoneal shunt is the procedure of choice for hydrocephalus. Various complications of ventriculoperitoneal shunts
were reported. Abdominal complications involving the distal tip
of the catheter make the majority of the complications. In this case
report we present a case of incisional hernia occurring in a patient
who underwent fixation of ventriculoperitoneal shunt followed by
revision of the shunt after a while.
Fatal Condition of Aortic Dissection Produces Symptoms of Sudden and Tearing ...semualkaira
Aortic dissection is a very difficult condition in which the inner
sheath of the aortic wall is torn without tearing the outer sheath.
This causes blood to enter the aortic wall through the tear, which
further splits the mediastinum and creates a new channel in the
aortic wall. The serious and often fatal condition of aortic dissection produces symptoms of sudden and tearing chest pain. Although aortic dissection mostly occurs in people around the age of
60, the peak incidence in people with Marfan syndrome is between
20 and 40 years of age.
Deletion of TLR4 Ameliorates Inflammation Response and Apoptosis in Septic Ca...semualkaira
Septic cardiomyopathy (SCM) is featured by
severe myocardial dysfunction and remains one of the lethal complications in clinical sepsis. Toll-like receptor 4 (TLR4) signaling
is known as a classical innate pathway in heart diseases, whereas
the precise underlying mechanism of TLR4 in SCM remains elusive. This study was designed to examine the specific role of TLR4
in SCM with a focus on inflammation and apoptosis.
Prospective Study of Acute Appendicitis with its Clinical, Radiological Profi...semualkaira
Acute appendicitis is the most common condition encountered in general surgical practice. Alvarado and Modified Alvarado Scores (MASS) are the commonly used scoring
systems for its diagnosis, but its performance has been found to
be poor in certain populations. Hence, we compared the RIPASA
score with MASS, to find out which is a better diagnostic tool for
acute appendicitis in the Indian population.
Surgery or Endovascular Treatment, which is the Better Way to Treat Acute and...semualkaira
To investigate the influence of surgical and endovascular treatment on the prognosis of acute and chronic mesenteric ischemia and to further evaluate whether endovascular
treatment can reduce postoperative complications by performing
a meta-analysis.
Rare Case Of Primary Pulmonary Dedifferentiated Liposarcomasemualkaira
Liposarcoma is a relatively common soft tissue sarcoma, but primary pulmonary liposarcomas are extremely rare, expecially for
dedifferentiated subtype. We report the case of a 44-year-old African woman, healed from SARS-Covid, who presented with a 8
cm right lung ilary mass and underwent to a right intrapericardial pneumonectomy with diaphragmatic and pleural resections.
Histological test confirmed diagnosis of dedifferentiated primary
pulmonary liposarcoma. The patient recovered well having an uncomplicated postoperative course and was discharged after 7 days.
On four months follow up the patient was still alive and without
evidence of disease. More studies have to be conducted because
very few cases are reported in literature.
Psychological Impact and Sexual Behavior in Patients with Genital and Anal Co...semualkaira
Genital warts are benign viral tumors of the skin or mucous membranes, due to human papillomaviruses. Rare are the authors who
insist on studying the psycho-affective and sexual impact of this
condition.
A Case Report of Hypothermia Rescued by Veno-Arterial Extracorporeal Membrane...semualkaira
Severe hypothermia is a life-threatening condition that often causes hemodynamic instability or cardiac arrest
and carries a high risk of mortality. The use of VA-ECMO in this
indication has greatly improved the prognosis of patients.
Experimental Analysis of Tear Fluid and their Processing for the Diagnosis of...semualkaira
A pilot analysis of the tear fluid of patients with multiple sclerosis (MS) collected by glass microcapillary was performed using
various experimental methods: liquid chromatography-mass spectrometry, Raman spectroscopy
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
Here is the updated list of Top Best Ayurvedic medicine for Gas and Indigestion and those are Gas-O-Go Syp for Dyspepsia | Lavizyme Syrup for Acidity | Yumzyme Hepatoprotective Capsules etc
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
ABDOMINAL TRAUMA in pediatrics part one.drhasanrajab
Abdominal trauma in pediatrics refers to injuries or damage to the abdominal organs in children. It can occur due to various causes such as falls, motor vehicle accidents, sports-related injuries, and physical abuse. Children are more vulnerable to abdominal trauma due to their unique anatomical and physiological characteristics. Signs and symptoms include abdominal pain, tenderness, distension, vomiting, and signs of shock. Diagnosis involves physical examination, imaging studies, and laboratory tests. Management depends on the severity and may involve conservative treatment or surgical intervention. Prevention is crucial in reducing the incidence of abdominal trauma in children.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
2. United Prime Publications LLC., https://acmcasereport.org/ 2
Volume 11 Issue 13 -2023 Mini Review
Type II: medial head of the gastrocnemius is fixed in a more lateral
position [17].
Type III: accessory structure of the gastrocnemius muscle entraps
the popliteal artery [17].
Type IV: popliteal artery courses below the popliteal muscle [17].
Type V: incarceration due to the anomalous location of the pop-
liteal vein [17].
Type VI: other variations [17].
It was first documented in 1879 in Edinburgh by medical student
Anderson Stuart, who dissected an amputated leg. However, it was
only in 1959 that Hammings wrote the first surgical case of pop-
liteal artery entrapment [12]. In Brazil, Ximenes and Ristow wrote
the first national case report and literature on the subject between
1991 and 1995 [13].
The population that is most affected by PAES are young men, on
average 32 years old, often with a habit of practicing sports, es-
pecially for functional classification, without risk factors for ath-
erosclerosis [4]. Type IV is most frequently affected, followed by
Type II and III, with the unilateral artery being more typical [4,14]
There are no specific symptoms, therefore, it presents itself in a
variable and intermittent way. With 80% of cases asymptomatic,
complaints will depend on the progression of the pathology. This
scenario, combined with the low number of cases on a daily ba-
sis, makes it difficult to diagnose PAES early, which makes it nec-
essary to consider possible differential diagnoses [5]. Symptoms
may include intermittent claudication, pain in the feet and calves
after exercise, cramps, paresthesia and hypothermia. Symptoms
tend to improve when the patient rests or changes position. In cas-
es of long-lasting PAES, pain may be associated even with relaxed
muscles [2, 5, 15]. The physical examination is essential and must
be well researched. Its characteristics are the reduction or absence
of the amplitude of the pedal and tibial pulses, especially in dorsi-
flexion or plantar hyperextension [16].
For the diagnosis to be given in a satisfactory time, a high level of
suspicion and elimination of differential diagnoses are necessary,
such as chronic compartment syndrome, neurogenic claudication,
peripheral atherosclerosis and cystic disease of the popliteal artery.
To follow an appropriate clinical logic, it is essential to be aware
of the pain characteristics of each diagnosis, so there will be no
delays in the treatment of PAES [14]. Adequate clinical training
will prevent complications such as arterial stenosis, emboli, aneu-
rysm, inability to perform physical activities, thromboembolism
and acute limb ischemia [7].
The current diagnostic imaging arsenal allows the investigation
of PAS in an incisive way, whether with radiography, echo-dop-
pler, tomography angiography, magnetic resonance angiography
or dynamic arteriography. Initially, radiography may be useful to
rule out bony or cartilaginous abnormalities that may compress
the popliteal artery [25]. However, soft tissues absent on an x-ray,
even if calcified, may not be seen on this exam. The ankle-brachial
index is a recommended and auxiliary method for differential di-
agnosis as it is non-invasive, but it is more applied to obstructive
diseases. As an indication of PAES, studies show a decrease of 30
to 50% in the index, but do not exclude other pathologies [25].
Echo Doppler has become increasingly important in the inves-
tigation of patients with suspected PAS, as this imaging method
has the advantage of being fast, highly informative about arterial
function and non-invasive [5]. However, it has the disadvantage of
being an operator-dependent method.
Like dynamic arteriography, echo-doppler is performed with the
foot in a neutral position and with provocative maneuvers, such as
active plantar flexion, as compression of the popliteal artery dur-
ing plantar flexion is diagnostic evidence of PAES. However, the
provocation maneuver has its value questioned, despite the good
performance of echo-doppler, its use for diagnosing PAES should
not be based on the isolated provocation maneuver [5].
Tomography is useful for demonstrating the anatomical relation-
ship of the soft tissues in the popliteal fossa, such as the relationship
between the gastrocnemius muscle and the popliteal artery, but it
is an exam that uses ionizing radiation and iodinated contrast. Its
nature is more confirmatory, with great utility in identifying PAS
when arteriography and positional tests are not accurate [6,7].
Computed tomography angiography (CTA) with iodinated con-
trast may be useful in investigating pathologies associated with
complaints of atypical lameness. Separate progressive scans can
be performed with dorsiflexion to specifically look for signs of
popliteal entrapment. CTA can demonstrate mild to severe pop-
liteal stenosis, popliteal artery occlusion, and even popliteal vein
compression [21].
Magnetic resonance imaging allows for a better study of popliteal
anatomy without the use of ionizing radiation or intravenous io-
dinated contrast, with high contrast between muscles, bones, vas-
cular structures and the adipose layer. It is the imaging modality
that facilitates the identification of the etiological factor of this
syndrome, through a fast spin or spin-echo sequence, which may
indicate a loss of flow in the popliteal artery due to some existing
pathology. The angiographic technique is the one that best assesses
artery entrapment, especially during dorsal flexion [22,23].
The treatment of PAES is considered based on the anatomical or
functional classification and progression of the syndrome. When
decompression of the popliteal artery is performed early, the surgi-
cal plan will aim to correct the anatomical correction of the mus-
culotendinous structures and vascular variations, while late treat-
ment may involve the correction of associated vascular injuries.
([14,25]. In classifying PAES by anatomical variation, correction
of the artery and gastrocnemius and/or popliteal muscles is neces-
sary, in some cases, repair of the popliteal vein [14].
3. United Prime Publications LLC., https://acmcasereport.org/ 3
Volume 11 Issue 13 -2023 Mini Review
In functional PAES, myofascial release is performed. It was ob-
served that maintaining the fascia open and suturing only the skin
tissue presented a greater chance of symptom remission. Further-
more, in 1992, a new technique using the medial approach had a
more satisfactory recovery than the posterior S-shaped approach,
as done in studies from 1985 [24]. Recently, botulinum toxin has
been used as a non-invasive method to improve symptoms, how-
ever, it is not yet a concrete indication [25]. The toxin is used in the
context of treating compartment syndrome, in which it was able
to reduce pressure by 50% in up to 9 months. The most common
adverse effect is hypotonia [26]. Prophylactic treatment is being
studied in the limb contralateral to the limb with symptomatic
PAES [25].
PAES is a rare condition with variable clinical presentation. Its
definitive diagnosis depends on imaging tests and should be part of
the differential diagnosis of intermittent claudication in young pa-
tients. Contrast imaging exams, despite being invasive, seal the di-
agnosis and allow for adequate surgical planning. Surgical decom-
pression is the most used therapeutic modality and the approach
varies depending on the classification as anatomical or functional.
PAES is a rare pathology, suspected in young patients with claudi-
cation that impacts quality of life, but with a good prognosis.
References
1. Stuart TPA. Note on a variation in the course of the popliteal artery.
J Anat Physiol. 1879; 13: 162-5.
2. Carneiro Júnior FCF, Carrijo ENDA, Araújo ST, Nakano LCU, de
Amorim JE, Cacione DG. Popliteal artery entrapment syndrome: A
case report and review of the literature. Am J Case Rep. 2018; 19:
29-34.
3. Hamming JJ. Intermittent claudication at an early age, due to an
anomalous course of the popliteal artery. Angiology. 1959: 10: 369-
70.
4. Collins PS, McDonald PT, Lim RC. Popliteal artery entrapment: An
evolving syndrome. J Vasc Surg. 1989; 10: 484-9.
5. Sinha S, Houghton J, Holt PJ, Thompson MM, Loftus IM, Hinchliffe
RJ. Popliteal entrapment syndrome. J Vasc Surg. 2012; 55(1): 252-
62.
6. Turnipseed WD. Functional popliteal artery entrapment syndrome:
a poorly understood and often missed diagnosis that is frequently
mistreated. J Vasc Surg. 2009; 49(5): 1189-95.
7. Almeida MJ, Yoshida WB, Melo NR. Síndrome do aprisionamento
da artéria poplítea. J Vasc Bras. 2003.
8. Castiglia V. Síndrome do aprisionamento da artéria poplítea. Revisão
de literatura. In: Maffei FHA, Lastória S, Yoshida WB, Rollo HA.
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