Phagocytosis is a process where phagocytes like neutrophils, macrophages, and dendritic cells ingest and destroy pathogens and foreign particles. These immune cells engulf microorganisms through phagocytosis, with neutrophils rapidly responding to acute inflammation and macrophages predominating in chronic inflammation. Phagocytosis involves cells engulfing pathogens to form a phagosome, which then fuses with lysosomes to form a phagolysosome and destroy the captured microorganism.