This document summarizes key events involving the Persian Empire, Macedonia, and the conquests of Alexander the Great from the 500s BC to 300s BC. It discusses the Persian Wars between Greece and Persia, the rule of King Philip II who transformed Macedonia into a powerful military force, and his son Alexander the Great's conquest of the massive Persian Empire between 334 BC to 323 BC, spreading Greek culture across a vast region. Alexander's army utilized innovative tactics like the phalanx and companion cavalry and he employed principles of warfare to achieve his objectives before his early death in 323 BC, leaving a legacy of a united East and West.