This document discusses the classification and rehabilitation of peripheral nerve lesions. It classifies lesions as neurapraxia (first degree), axonotmesis (second degree), or neurotemesis (third degree). It then provides details on individual nerve lesions including signs, symptoms, prognosis, and rehabilitation approaches. Common nerves discussed include the radial, median, ulnar, femoral, sciatic, common peroneal, and posterior tibial nerves. Rehabilitation generally involves pain management, motor relearning exercises, sensory reeducation, and limb protection strategies.
The document describes how to examine muscles through inspection and palpation. Key points include:
- Inspecting for asymmetry, wasting, hypertrophy, fasciculations and involuntary movements when exposing muscles fully
- Palpating muscles to assess bulk
- Common abnormalities include different types of muscle wasting, fasciculations, myoclonic jerks and tremors
- Assessing tone by moving joints passively and noting increased or decreased resistance
- Examining reflexes through superficial and deep tendon reflexes at different levels
- Testing movement, power, coordination and apraxia through various maneuvers
This document summarizes the steps for examining a patient's motor and sensory systems. It outlines how to assess muscle tone, reflexes, strength, coordination, and sensation. The motor exam evaluates muscles for wasting, fasciculations, and abnormalities in tone. Reflexes like biceps, triceps, knee, and ankle jerks are tested. Strength is graded from 0-5. Coordination is tested using finger-nose, heel-shin, and rapid alternating movements. Sensation is assessed over dermatomes for pain, temperature, vibration and fine touch. The goal is to localize signs to upper or lower motor neuron lesions.
Dr. Araib Kaleem's document discusses joint dislocations and subluxations. It provides definitions and descriptions of dislocations, subluxations, and specific types of dislocations such as traumatic dislocations. Causes, symptoms, signs, treatments, and complications of common dislocations are described, including dislocations of the shoulder, hip, knee, and elbow. Reduction techniques and post-treatment management are outlined for various joint dislocations.
Dr. Araib Kaleem's document discusses joint dislocations and subluxations. It provides definitions and descriptions of dislocations, subluxations, and specific types of dislocations such as traumatic dislocations. Causes, symptoms, signs, and treatments of dislocations are described. Examples of shoulder, hip, knee, and elbow dislocations are discussed in detail including mechanisms of injury, clinical features, management techniques such as closed reduction, and potential complications. Radiographs are important for diagnosing dislocations and specific reduction techniques are described for different joints.
This document discusses spinal anatomy, trauma, and injury. It covers the epidemiology, mechanisms, classifications, diagnosis, and management of spinal cord injuries. Some key points include:
- The cervical spine has greater range of motion while the thoracic and lumbar vertebrae are more rigid.
- Spinal cord injuries can be complete or incomplete. Complete injuries have no motor or sensory function below the level of injury while incomplete injuries have some spared function.
- Common mechanisms of injury are motor vehicle accidents, falls, and sports/recreation injuries. Indirect injuries from compression are most likely to cause significant damage.
- Imaging like CT and MRI are important for diagnosis but patient stabilization takes priority over imaging in trauma situations
This document discusses spinal anatomy, trauma, and injury. It covers the epidemiology, mechanisms, classifications, diagnosis, and management of spinal cord injuries. Some key points include:
- The cervical spine has greater range of motion while the thoracic and lumbar vertebrae are more rigid.
- Spinal cord injuries can be complete or incomplete. Complete injuries have no motor or sensory function below the level of injury while incomplete injuries have some spared function.
- Common mechanisms of injury are motor vehicle accidents, falls, and sports/recreation injuries. Indirect injuries from compression are most likely to cause significant damage.
- Imaging like CT and MRI are important for diagnosis but patient stabilization takes priority over imaging in trauma situations
The document discusses various nerves of the lower limb including:
1. The femoral nerve which innervates the quadriceps and hip flexors and can cause paralysis of these muscles if injured.
2. The inferior gluteal nerve which innervates the gluteus maximus and injury causes inability to extend the hip.
3. The superior gluteal nerve which innervates hip abductors like gluteus medius and injury causes Trendelenburg gait.
4. The obturator nerve which innervates hip adductors. Injuries to the sciatic, tibial, common peroneal/fibular nerves can also cause muscle weakness, sensory loss
This document discusses vertebral fractures and spinal cord injuries. It begins by describing the anatomy of the vertebral column and typical vertebrae. It then discusses different types of lumbar vertebral fractures including wedge compression fractures, burst fractures, flexion-distraction injuries, and fracture-dislocations. Emergency management of spinal injuries is outlined including immobilization techniques. Spinal cord injuries are also summarized, covering topics like pathophysiology, classifications, consequences, and specific syndromes like central cord syndrome. Acute phase conditions like spinal shock and neurogenic shock are defined.
The document describes how to examine muscles through inspection and palpation. Key points include:
- Inspecting for asymmetry, wasting, hypertrophy, fasciculations and involuntary movements when exposing muscles fully
- Palpating muscles to assess bulk
- Common abnormalities include different types of muscle wasting, fasciculations, myoclonic jerks and tremors
- Assessing tone by moving joints passively and noting increased or decreased resistance
- Examining reflexes through superficial and deep tendon reflexes at different levels
- Testing movement, power, coordination and apraxia through various maneuvers
This document summarizes the steps for examining a patient's motor and sensory systems. It outlines how to assess muscle tone, reflexes, strength, coordination, and sensation. The motor exam evaluates muscles for wasting, fasciculations, and abnormalities in tone. Reflexes like biceps, triceps, knee, and ankle jerks are tested. Strength is graded from 0-5. Coordination is tested using finger-nose, heel-shin, and rapid alternating movements. Sensation is assessed over dermatomes for pain, temperature, vibration and fine touch. The goal is to localize signs to upper or lower motor neuron lesions.
Dr. Araib Kaleem's document discusses joint dislocations and subluxations. It provides definitions and descriptions of dislocations, subluxations, and specific types of dislocations such as traumatic dislocations. Causes, symptoms, signs, treatments, and complications of common dislocations are described, including dislocations of the shoulder, hip, knee, and elbow. Reduction techniques and post-treatment management are outlined for various joint dislocations.
Dr. Araib Kaleem's document discusses joint dislocations and subluxations. It provides definitions and descriptions of dislocations, subluxations, and specific types of dislocations such as traumatic dislocations. Causes, symptoms, signs, and treatments of dislocations are described. Examples of shoulder, hip, knee, and elbow dislocations are discussed in detail including mechanisms of injury, clinical features, management techniques such as closed reduction, and potential complications. Radiographs are important for diagnosing dislocations and specific reduction techniques are described for different joints.
This document discusses spinal anatomy, trauma, and injury. It covers the epidemiology, mechanisms, classifications, diagnosis, and management of spinal cord injuries. Some key points include:
- The cervical spine has greater range of motion while the thoracic and lumbar vertebrae are more rigid.
- Spinal cord injuries can be complete or incomplete. Complete injuries have no motor or sensory function below the level of injury while incomplete injuries have some spared function.
- Common mechanisms of injury are motor vehicle accidents, falls, and sports/recreation injuries. Indirect injuries from compression are most likely to cause significant damage.
- Imaging like CT and MRI are important for diagnosis but patient stabilization takes priority over imaging in trauma situations
This document discusses spinal anatomy, trauma, and injury. It covers the epidemiology, mechanisms, classifications, diagnosis, and management of spinal cord injuries. Some key points include:
- The cervical spine has greater range of motion while the thoracic and lumbar vertebrae are more rigid.
- Spinal cord injuries can be complete or incomplete. Complete injuries have no motor or sensory function below the level of injury while incomplete injuries have some spared function.
- Common mechanisms of injury are motor vehicle accidents, falls, and sports/recreation injuries. Indirect injuries from compression are most likely to cause significant damage.
- Imaging like CT and MRI are important for diagnosis but patient stabilization takes priority over imaging in trauma situations
The document discusses various nerves of the lower limb including:
1. The femoral nerve which innervates the quadriceps and hip flexors and can cause paralysis of these muscles if injured.
2. The inferior gluteal nerve which innervates the gluteus maximus and injury causes inability to extend the hip.
3. The superior gluteal nerve which innervates hip abductors like gluteus medius and injury causes Trendelenburg gait.
4. The obturator nerve which innervates hip adductors. Injuries to the sciatic, tibial, common peroneal/fibular nerves can also cause muscle weakness, sensory loss
This document discusses vertebral fractures and spinal cord injuries. It begins by describing the anatomy of the vertebral column and typical vertebrae. It then discusses different types of lumbar vertebral fractures including wedge compression fractures, burst fractures, flexion-distraction injuries, and fracture-dislocations. Emergency management of spinal injuries is outlined including immobilization techniques. Spinal cord injuries are also summarized, covering topics like pathophysiology, classifications, consequences, and specific syndromes like central cord syndrome. Acute phase conditions like spinal shock and neurogenic shock are defined.
This document provides an overview of spinal trauma. It begins with relevant spinal anatomy and the epidemiology of spinal injuries. The most common mechanisms of injury are motor vehicle accidents and falls. Clinical signs include neurological deficits that correspond to the level and completeness of injury. Radiological imaging such as X-rays, CT, and MRI are used to identify fractures and spinal instability. Early management focuses on immobilization, corticosteroids, and treating associated conditions like neurogenic shock. Surgical stabilization is indicated for incomplete injuries with neural compression or unstable fractures with neurological deficits. The goals of treatment are to preserve neurological function, minimize compression, stabilize the spine, and rehabilitate the patient.
Peripheral nerve injuries can occur through various mechanisms and be classified in different ways. The median, radial, and ulnar nerves are commonly injured in the upper limb. Examination of specific muscles innervated by each nerve helps to localize the level and severity of injury. Precise history taking and clinical assessment including motor, sensory and trophic changes are needed to diagnose peripheral nerve lesions.
Peripheral nerve injuries can occur through various mechanisms and be classified in different ways. The median, radial, and ulnar nerves are commonly injured in the upper limb. Examination of specific muscles innervated by each nerve helps to localize the level and severity of injury. Precise history taking and clinical assessment including motor, sensory and trophic changes are needed to diagnose peripheral nerve lesions.
Peripheral nerve injuries can occur through various mechanisms including trauma, compression, and ischemia. Peripheral nerves have a complex anatomy consisting of bundles of axons surrounded by connective tissue layers. Injuries are classified based on the severity of axonal damage. Common peripheral nerve injuries involve the radial, median, and long thoracic nerves. A thorough history and focused neurological examination are needed to localize the site of injury and determine the functional impairment.
This document provides information about examining the motor system, including anatomy of motor pathways in the brain and spinal cord, inspection of muscles, and testing of muscle tone, power, and specific muscles. It describes how to examine muscles of the shoulder, elbow, wrist/hand, hip, and other areas, including specific tests to evaluate individual muscles like deltoid, biceps, gluteus maximus, and others. The document provides detailed instructions on posture and resistance for testing each muscle.
This document provides an overview of spastic paraplegia, including its causes, clinical features, and approach to patients. Spastic paraplegia is defined as paralysis or weakness of both lower limbs due to a bilateral pyramidal tract lesion in the spinal cord or brain. The causes can be cortical, spinal cord disorders, or non-compressive myelopathies. The clinical approach involves taking a detailed history and performing a neurological exam to localize the lesion and determine the likely etiology. Investigations may include blood tests, imaging of the spine, and other tests depending on suspected causes.
The sciatic nerve is the largest nerve in the body, originating from the lower spine and extending down each leg. Foot drop is caused by weakness of the muscles that lift the front of the foot, usually due to injury or compression of the peroneal nerve branch of the sciatic nerve. Symptoms include inability to lift the foot and an exaggerated walking gait. Treatment depends on the underlying cause but may include bracing, physical therapy, nerve stimulation, or tendon transfer surgery.
The document provides guidance on performing a motor system examination, including assessing muscle bulk, tone, power, and coordination. It outlines how to examine the muscles of the neck, shoulders, arms, trunk and legs. Key points covered include testing specific muscle groups, identifying patterns of weakness, avoiding misleads, and grading scales for muscle tone. The examination involves inspection, palpation, specific movements against resistance and evaluation of posture and gait.
The document discusses brachial plexus injuries, which involve damage to the network of nerves that control the arm and hand. It describes the anatomy of the brachial plexus and the mechanisms, classifications, signs and symptoms, investigations, and management of both adult and obstetric brachial plexus injuries. Specific injuries like Erb's palsy and Klumpke's palsy are also explained. The prognosis depends on the level and severity of the injury, with upper plexus injuries having a better prognosis than lower plexus or total plexus lesions. Early surgical intervention may be needed for severe injuries or root avulsions.
Peripheral nerve injuries can vary in cause and severity. Common sites of injury include the brachial plexus, radial nerve, median nerve, ulnar nerve, femoral nerve, sciatic nerve, and common peroneal nerve. Injuries are classified based on the extent of anatomical disruption, with neuropraxia having minimal disruption and neurotmesis being a complete severance. Clinical examination involves assessing motor function, sensation, reflexes, and trophic changes to determine the level and severity of injury.
This document discusses the structure and function of peripheral nerves, as well as types and management of peripheral nerve injuries. Some key points:
- Peripheral nerves are composed of axons, connective tissue and blood vessels. They transmit sensory and motor signals between different body parts.
- Common sites of peripheral nerve injury include the radial, ulnar and median nerves. Injuries can cause sensory loss, muscle weakness or wasting.
- Management depends on the severity and location of injury. Conservative treatment focuses on prevention of contractures while surgical intervention may be needed for open wounds or lack of recovery. Primary repair within hours or delayed repair within 2 weeks of injury can reattach severed nerve fibers.
Spinal cord injuries complete topic about it and how to make good rehabilitation for the patient with spinal cord injuries .
wish it help people
my pleasure :)
Mostafa shakshak
Spasticity, rigidity, hypotonia, dystonia, decerebrate rigidity, and decorticate rigidity are abnormal tones that can occur. Examination of tone includes initial observation, passive and active motion testing using scales like the Modified Ashworth Scale. Typical patterns of spasticity in upper and lower limbs are described for upper motor neuron lesions.
This document provides information on the diagnosis and classification of nerve injuries, as well as details on specific nerves including their anatomy, causes of injury, clinical features, and management approaches. It discusses the axillary, radial, ulnar, median, sciatic, femoral, and lumbosacral plexus nerves. Diagnosis involves history, examination, and investigations such as nerve conduction studies, electromyography, and imaging. Surgical management of nerve injuries includes neurolysis, nerve repair, grafting, and the use of nerve conduits.
This document provides an overview of the neurological examination of the lower limb. It discusses the anatomy of the lumbar and sacral plexuses and the major nerves that innervate the lower limb muscles. It then describes how to examine the lower limb muscles, including assessing bulk, tone, power, and coordination. Specific techniques for evaluating bulk, tone, and causes of muscle atrophy or hypertrophy are outlined. The document emphasizes the importance of differentiating neurological from non-neurological causes of abnormal findings.
Lower limb neurological examination frequently appears in OSCEs. You’ll be expected to pick up the relevant clinical signs using your examination skills. This lower limb neurological examination OSCE guide provides a clear, concise, step-by-step approach to performing a neurological examination of the lower limb
This document discusses peripheral nerve injuries. It begins by describing the structure and components of peripheral nerves. It then discusses the signs and symptoms of different types of peripheral nerve injuries like radial nerve, ulnar nerve and median nerve palsies. The document also covers the pathophysiology of nerve injury including Wallerian degeneration. It describes the diagnostic tools like electrodiagnostic studies and various treatment options for peripheral nerve injuries including nerve repair techniques.
This document discusses wrist drop, finger drop, and foot drop caused by radial nerve palsy. It provides details on the anatomy of the radial nerve and explains how injuries at different points can cause wrist drop or finger drop. For foot drop, it describes the anatomy of the leg and discusses how peroneal nerve injuries or issues with the sciatic nerve or L5 root can cause weakness of the dorsiflexors. It outlines the clinical features, diagnostic process, and treatment options including conservative care, physical therapy, splinting, and in some cases surgery.
The document discusses lumbar disc herniation, including its anatomy, causes, symptoms, diagnosis, and treatment options. It describes the functional spinal unit made up of vertebrae and intervertebral discs. Lumbar disc herniation occurs when a tear in the outer ring of the disc allows the inner nucleus pulposus to protrude out. Common symptoms are back pain radiating into the leg. Diagnosis involves physical exam and imaging tests like MRI. Treatment options include conservative care with rest and medications or surgical procedures like discectomy to remove herniated disc material pressing on nerves.
1. Spinal shock occurs immediately after complete transection of the spinal cord and is characterized by a complete loss of all reflexes below the level of lesion lasting 2-6 weeks.
2. Early recovery of reflexes begins after spinal shock and includes weak return of the stretch reflex and appearance of new reflexes like the plantar reflex.
3. Full recovery of reflexes may take 6 months as reflexes further strengthen and autonomic functions partially return through reorganization at the spinal level.
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Oleg Kshivets
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
This document provides an overview of spinal trauma. It begins with relevant spinal anatomy and the epidemiology of spinal injuries. The most common mechanisms of injury are motor vehicle accidents and falls. Clinical signs include neurological deficits that correspond to the level and completeness of injury. Radiological imaging such as X-rays, CT, and MRI are used to identify fractures and spinal instability. Early management focuses on immobilization, corticosteroids, and treating associated conditions like neurogenic shock. Surgical stabilization is indicated for incomplete injuries with neural compression or unstable fractures with neurological deficits. The goals of treatment are to preserve neurological function, minimize compression, stabilize the spine, and rehabilitate the patient.
Peripheral nerve injuries can occur through various mechanisms and be classified in different ways. The median, radial, and ulnar nerves are commonly injured in the upper limb. Examination of specific muscles innervated by each nerve helps to localize the level and severity of injury. Precise history taking and clinical assessment including motor, sensory and trophic changes are needed to diagnose peripheral nerve lesions.
Peripheral nerve injuries can occur through various mechanisms and be classified in different ways. The median, radial, and ulnar nerves are commonly injured in the upper limb. Examination of specific muscles innervated by each nerve helps to localize the level and severity of injury. Precise history taking and clinical assessment including motor, sensory and trophic changes are needed to diagnose peripheral nerve lesions.
Peripheral nerve injuries can occur through various mechanisms including trauma, compression, and ischemia. Peripheral nerves have a complex anatomy consisting of bundles of axons surrounded by connective tissue layers. Injuries are classified based on the severity of axonal damage. Common peripheral nerve injuries involve the radial, median, and long thoracic nerves. A thorough history and focused neurological examination are needed to localize the site of injury and determine the functional impairment.
This document provides information about examining the motor system, including anatomy of motor pathways in the brain and spinal cord, inspection of muscles, and testing of muscle tone, power, and specific muscles. It describes how to examine muscles of the shoulder, elbow, wrist/hand, hip, and other areas, including specific tests to evaluate individual muscles like deltoid, biceps, gluteus maximus, and others. The document provides detailed instructions on posture and resistance for testing each muscle.
This document provides an overview of spastic paraplegia, including its causes, clinical features, and approach to patients. Spastic paraplegia is defined as paralysis or weakness of both lower limbs due to a bilateral pyramidal tract lesion in the spinal cord or brain. The causes can be cortical, spinal cord disorders, or non-compressive myelopathies. The clinical approach involves taking a detailed history and performing a neurological exam to localize the lesion and determine the likely etiology. Investigations may include blood tests, imaging of the spine, and other tests depending on suspected causes.
The sciatic nerve is the largest nerve in the body, originating from the lower spine and extending down each leg. Foot drop is caused by weakness of the muscles that lift the front of the foot, usually due to injury or compression of the peroneal nerve branch of the sciatic nerve. Symptoms include inability to lift the foot and an exaggerated walking gait. Treatment depends on the underlying cause but may include bracing, physical therapy, nerve stimulation, or tendon transfer surgery.
The document provides guidance on performing a motor system examination, including assessing muscle bulk, tone, power, and coordination. It outlines how to examine the muscles of the neck, shoulders, arms, trunk and legs. Key points covered include testing specific muscle groups, identifying patterns of weakness, avoiding misleads, and grading scales for muscle tone. The examination involves inspection, palpation, specific movements against resistance and evaluation of posture and gait.
The document discusses brachial plexus injuries, which involve damage to the network of nerves that control the arm and hand. It describes the anatomy of the brachial plexus and the mechanisms, classifications, signs and symptoms, investigations, and management of both adult and obstetric brachial plexus injuries. Specific injuries like Erb's palsy and Klumpke's palsy are also explained. The prognosis depends on the level and severity of the injury, with upper plexus injuries having a better prognosis than lower plexus or total plexus lesions. Early surgical intervention may be needed for severe injuries or root avulsions.
Peripheral nerve injuries can vary in cause and severity. Common sites of injury include the brachial plexus, radial nerve, median nerve, ulnar nerve, femoral nerve, sciatic nerve, and common peroneal nerve. Injuries are classified based on the extent of anatomical disruption, with neuropraxia having minimal disruption and neurotmesis being a complete severance. Clinical examination involves assessing motor function, sensation, reflexes, and trophic changes to determine the level and severity of injury.
This document discusses the structure and function of peripheral nerves, as well as types and management of peripheral nerve injuries. Some key points:
- Peripheral nerves are composed of axons, connective tissue and blood vessels. They transmit sensory and motor signals between different body parts.
- Common sites of peripheral nerve injury include the radial, ulnar and median nerves. Injuries can cause sensory loss, muscle weakness or wasting.
- Management depends on the severity and location of injury. Conservative treatment focuses on prevention of contractures while surgical intervention may be needed for open wounds or lack of recovery. Primary repair within hours or delayed repair within 2 weeks of injury can reattach severed nerve fibers.
Spinal cord injuries complete topic about it and how to make good rehabilitation for the patient with spinal cord injuries .
wish it help people
my pleasure :)
Mostafa shakshak
Spasticity, rigidity, hypotonia, dystonia, decerebrate rigidity, and decorticate rigidity are abnormal tones that can occur. Examination of tone includes initial observation, passive and active motion testing using scales like the Modified Ashworth Scale. Typical patterns of spasticity in upper and lower limbs are described for upper motor neuron lesions.
This document provides information on the diagnosis and classification of nerve injuries, as well as details on specific nerves including their anatomy, causes of injury, clinical features, and management approaches. It discusses the axillary, radial, ulnar, median, sciatic, femoral, and lumbosacral plexus nerves. Diagnosis involves history, examination, and investigations such as nerve conduction studies, electromyography, and imaging. Surgical management of nerve injuries includes neurolysis, nerve repair, grafting, and the use of nerve conduits.
This document provides an overview of the neurological examination of the lower limb. It discusses the anatomy of the lumbar and sacral plexuses and the major nerves that innervate the lower limb muscles. It then describes how to examine the lower limb muscles, including assessing bulk, tone, power, and coordination. Specific techniques for evaluating bulk, tone, and causes of muscle atrophy or hypertrophy are outlined. The document emphasizes the importance of differentiating neurological from non-neurological causes of abnormal findings.
Lower limb neurological examination frequently appears in OSCEs. You’ll be expected to pick up the relevant clinical signs using your examination skills. This lower limb neurological examination OSCE guide provides a clear, concise, step-by-step approach to performing a neurological examination of the lower limb
This document discusses peripheral nerve injuries. It begins by describing the structure and components of peripheral nerves. It then discusses the signs and symptoms of different types of peripheral nerve injuries like radial nerve, ulnar nerve and median nerve palsies. The document also covers the pathophysiology of nerve injury including Wallerian degeneration. It describes the diagnostic tools like electrodiagnostic studies and various treatment options for peripheral nerve injuries including nerve repair techniques.
This document discusses wrist drop, finger drop, and foot drop caused by radial nerve palsy. It provides details on the anatomy of the radial nerve and explains how injuries at different points can cause wrist drop or finger drop. For foot drop, it describes the anatomy of the leg and discusses how peroneal nerve injuries or issues with the sciatic nerve or L5 root can cause weakness of the dorsiflexors. It outlines the clinical features, diagnostic process, and treatment options including conservative care, physical therapy, splinting, and in some cases surgery.
The document discusses lumbar disc herniation, including its anatomy, causes, symptoms, diagnosis, and treatment options. It describes the functional spinal unit made up of vertebrae and intervertebral discs. Lumbar disc herniation occurs when a tear in the outer ring of the disc allows the inner nucleus pulposus to protrude out. Common symptoms are back pain radiating into the leg. Diagnosis involves physical exam and imaging tests like MRI. Treatment options include conservative care with rest and medications or surgical procedures like discectomy to remove herniated disc material pressing on nerves.
1. Spinal shock occurs immediately after complete transection of the spinal cord and is characterized by a complete loss of all reflexes below the level of lesion lasting 2-6 weeks.
2. Early recovery of reflexes begins after spinal shock and includes weak return of the stretch reflex and appearance of new reflexes like the plantar reflex.
3. Full recovery of reflexes may take 6 months as reflexes further strengthen and autonomic functions partially return through reorganization at the spinal level.
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Oleg Kshivets
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
Integrating Ayurveda into Parkinson’s Management: A Holistic ApproachAyurveda ForAll
Explore the benefits of combining Ayurveda with conventional Parkinson's treatments. Learn how a holistic approach can manage symptoms, enhance well-being, and balance body energies. Discover the steps to safely integrate Ayurvedic practices into your Parkinson’s care plan, including expert guidance on diet, herbal remedies, and lifestyle modifications.
Clinic ^%[+27633867063*Abortion Pills For Sale In Tembisa Central19various
Clinic ^%[+27633867063*Abortion Pills For Sale In Tembisa Central Clinic ^%[+27633867063*Abortion Pills For Sale In Tembisa CentralClinic ^%[+27633867063*Abortion Pills For Sale In Tembisa CentralClinic ^%[+27633867063*Abortion Pills For Sale In Tembisa CentralClinic ^%[+27633867063*Abortion Pills For Sale In Tembisa Central
Osteoporosis - Definition , Evaluation and Management .pdfJim Jacob Roy
Osteoporosis is an increasing cause of morbidity among the elderly.
In this document , a brief outline of osteoporosis is given , including the risk factors of osteoporosis fractures , the indications for testing bone mineral density and the management of osteoporosis
Adhd Medication Shortage Uk - trinexpharmacy.comreignlana06
The UK is currently facing a Adhd Medication Shortage Uk, which has left many patients and their families grappling with uncertainty and frustration. ADHD, or Attention Deficit Hyperactivity Disorder, is a chronic condition that requires consistent medication to manage effectively. This shortage has highlighted the critical role these medications play in the daily lives of those affected by ADHD. Contact : +1 (747) 209 – 3649 E-mail : sales@trinexpharmacy.com
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Kat...rightmanforbloodline
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Katzung, Verified Chapters 1 - 66, Complete Newest Version.
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Katzung, Verified Chapters 1 - 66, Complete Newest Version.
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Katzung, Verified Chapters 1 - 66, Complete Newest Version.
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Katzung, Verified Chapters 1 - 66, Complete Newest Version.
Cell Therapy Expansion and Challenges in Autoimmune DiseaseHealth Advances
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Does Over-Masturbation Contribute to Chronic Prostatitis.pptxwalterHu5
In some case, your chronic prostatitis may be related to over-masturbation. Generally, natural medicine Diuretic and Anti-inflammatory Pill can help mee get a cure.
2. CLASSIFICATION:
Neurapraxia First degree Conduction block
(ischemic or local
demyelination)
anatomically normal
Axonotemesis Second degree Axonal interruption only
Neurotemesis Third degree Nerve fiber interruption
axon and myelin sheath
,with connective tissue
damage ( in partial
demyelination ) or with
nerve severance (in
complete damage)
3. 1.NEURAPRAXIA:
Temporary interruption of conduction without axonal interruption.
Pathology:
N.B: Basal lamina is preserved.
Clinical examinations and findings:
1.Weakness (or paralysis) in the muscles, decrease or loss of sensation
in regions.
2. Nerve conduction velocity is decreased.
5. 2.AXONOTEMESIS:
Interruption of nerve axon only. Basal lamina remains intact.
Clinical examinations and findings:
1.Weakness or paralysis, loss or decrease of sensation.
2.Nerve conduction velocity is reduced.
3. EMG shows fibrillation.
Prognosis:
Good, as basal lamina forms channels, in which proper regeneration
occurs .rate of recovery is 1-3 mm per day .
Rehabilitation:
As neurapraxia.
6. 3.NEUROTMESIS:
Interruption of all nerve.
Pathology:
Lesion of both basal lamina and neurolemmal sheath.
Clinical examinations and findings:
As complete axonotemesis.
Prognosis:
Regeneration is Poor, it needs surgical repair.
Rehabilitation:
As axonotemesis.
7. INDIVIDUAL PERIPHERAL NERVE
LESIONS
1-Suprascapular nerve lesion:
Signs and symptoms:
1.Weakness or paralysis of supraspinatous (shoulder abduction) and infraspinatous ( shoulder external
rotation).
2.Normal sensation.
3.Normal deep reflexes.
4.Atrophy of both muscles.
5.Deepshoulder pain (aching).
Rehabilitation:
1.ES then graduated active shoulder abduction and external rotation.
2.Pain management: A-Sling at acute stage.
B-Heat & TENS for pain.
3.Limp protection: Avoid heavy lifting.
8. 2-LONG THORACIC NERVE LESION:
• Signs and symptoms:
1.Winging of the inferior angle of scapula, due to weakness of serratus
anterior , lead to weak of functional shoulder flexion and abduction
due to altered scapula mechanism .
2.Normal sensation.
3.Normal deep reflexes.
Rehabilitation:
1.Passive, then graduated active exercises for serratus anterior, passive
Scapular mobilization.
2.Limb protection: as the previous.
9. 3-MUSCULOCUTANEOUS NERVE
LESION:
Uncommon
Clinical assessment :
1.Weakness or paralysis of biceps, brachialis (+ - ) coracobrachialis. This lead to
functional weakness in combined flexion-pronation elbow.
2.Sensory loss over lateral forearm.
3.Loss of biceps deep tendon reflex.
4.Atrophy of biceps and brachialis may occur.
Rehabilitation
1-Passive movement. ES then graduated active exercises.
2.Limb protection:
A- Sling
B- Avoid heavy lifting.
C-Avoid high velocity elbow extension.
10. 4-AXILLARY NERVE LESION:
Clinical assessment:
1.Weakness or paralysis of deltoid and teres minor. functional
weakness of shoulder flexion ,abduction ,lateral rotation .
2.Sensory loss over lateral aspect of shoulder
3.Normal deep reflexes.
4.Atrophy of deltoid.
5.May be shoulder pain.
12. 5-RADIAL NERVE
LESIONS:
1.Axillary level:
Due to shoulder dislocation or from Axillary crutches pressure.
Clinical assessment:
1.Weakness or paralysis of triceps and all muscles supplied by radial
nerve. Functional loos of extension of elbow ,wrist and fingers
2.Sensory loss dorsal radial hand.
3.Loss of triceps and brachioradialis deep reflexes.
4- Drop wrist
13. 2.SPIRAL GROOVE LEVEL:
Duo to sleeping against hard surface & from slings.
Clinical assessment:
1.Weakness or paralysis of all muscles innervated by radial nerve(
including brachioradiails), except triceps, which leads to loss of
functional extension of wrist and hand only.
2.Same sensory loss.
3.Loss of brachioradialis deep reflex only.
14. 3.PROXIMAL FOREARM LESION
(POSTERIOR INTEROSSEUS BRANCH):
It is a pure motor nerve. It occurs due to lesion at the level of head of
radius.
Clinical assessment:
1.Weakness or paralysis in muscles distal to supinator and extensor
carpiradialis, This leads to loss of fingers extension and wrist
extension-ulnar deviation.
2.Normal sensation.
3. Normal deep reflexes.
15. 4-SUPERFICIAL SENSORY
BRANCH OF RADIAL NERVE
• Site of lesion in forearm at radial dorsal site
• Clinical assessment
• 1- Normal motor power
• 2-Sensory loss over dorsal radial hand
• 3-Normal deep reflexes
16. REHABILITATION OF RADIAL
NERVE LESION
• 1- Pain management :
• Heat and TENS
• 2-Motor relearning :Passive movement to affected joint
• ES then graduated active exercise to affected muscles
• 3-Senseory reeducation :
• 4- Limb protection:
• -cock up splint in mild extension
• -avoid heavy lifting
• Avoid wrist extension and supination
17. 6-MEDIAN NERVE LESIONS
• 1- upper arm lesion
• Clinical assessment
• 1-Weakness or paralysis in muscles supply by nerve including pronator
teres
• Loss of pronation , radial wrist flexion ,index flexion distal thumb
flexion and thumb opposition
• 2- sensory loss in thenar muscles
• 3-Atrophy of forearm and thenar muscles
• 4-Normal deep reflexes
18. 2-AT ELBOW LEVEL (PRONATOR
TERES SYNDROME)
• Clinical assessment:
• 1-Weakness or paralysis in muscles supply by nerve except pronator teres
• - Functional loss of radial wrist flexion ,index flexion and distal thumb
flexion and thump opposition
• Pronation is functionally intact but weak (no pronator quadratus)
• 2-Sensory loss in thenar muscles
• 3-Atrophy of forearm and thenar muscles
• 4-Normal deep reflexes
•
19. 3-ANTERIOR INTEROSSEUS NERVE LESION
• Clinical assessment
• 1-Weakness or paralysis in pronator quadratus ,FPL and FDP to
middle and index fingers
• Patient can not make zero by both thump and index
• 2- Normal sensation
• 3-Atrophy of distal anterior radial forearm forearm.
• Normal deep reflexes
20. 4-LESION OF MEDINA NERVE AT WRIST
(CARPAL TUNNEL SYNDROME)
• Clinical assessment :
• 1-Pain ,numbness ,and weakness in thumb index and middle fingers.
• pain radiate to elbow and shoulder
• Pain increase at sleeping ,driving and using hand
• 2-Weakness of thumb opposition.
• 3-Decrease or lost sensation in 3 and halve fingers
• 4-Atrophy of thenar muscles
• 5-Normal deep reflexes
21. REHABILITATION OF MEDIAN
NERVE LESION
• 1- Pain management:
• Deep cold LASER
• TENS
• US continuous
• Wrist splint in neutral position
• 2- Motor relearning:
• Passive movement to affected joint
• ES then graduated active exercise to affected muscles
• 3- Sensory relearning
• 4 -limb protection
22. 7-ULNAR NERVE LESION
• 1- Upper limb lesions
• Clinical assessment :
• 1- Weakness or paralysis of muscles supply by ulnar nerve
• Loss of ulnar wrist flexion, fingers add &abd and fingers flexion in little
and ring fingers and flex DIPJ and weak thumb adduction
• 2-Sensory loss in all ulnar nerve distribution
• 3- Normal deep reflexes
• 4-Atrophy of ulnar hand &ulnar forearm muscles
• 5-Mild claw in ulnar 2 fingers.
23. 2-AT ELBOW LEVEL WITHIN
CUBITAL TUNNEL
• Clinical assessment :
• 1-Weakness or paralysis of all muscles innervated by ulnar nerve except
flexors carpi ulnares.
• Functional loss of fingers add&abd ,thumb add and flexion of little fingers and
ring fingers at distal interphalangeal joints
• 2-Sensory loss in all ulnar nerve distribution
• 3- Normal deep reflexes
• 4-Atrophy of ulnar hand &ulnar forearm muscles
• 5-Mild claw in ulnar 2 fingers,
24. 3-AT WRIST LEVEL
• Between pisiform and hook of hamate
• clinical assessment :
• 1- Motor loss is only in ulnar innervated intrinsic hand muscles and
hypothenar muscles
• Loss of thumb add. And fingers add and abd .
• 2-Sensory loss
• 3-Atrophy of ulnar innervated intrinsic muscles
25. REHABILITATION OF ULNAR NERVE
INJURES
• 1- Pain management:
• Heat &TENS
• 2- Motor relearning:
• Passive movement to affected joint
• ES then graduated active exercise to affected muscles
• 3- Sensory reeducation
• 4 -Limb protection
26. 8-FEMORAL NERVE LESION
• Compressed at level of inguinal ligament
• Clinical assessment :
• 1-Weakness or paralysis of quadriceps and weak hip flexors
• -Functional loss of knee extension only
• 2-Sensory loss anteromedial aspect of thigh ,leg and foot
• 3-Decrease or lost knee jerk
• 4-Atrophy of quadriceps
27. REHABILITATION OF FEMORAL
NERVE LESION
• 1- Pain management:
• Heat &TENS
• Cane if there is pain during walking
• 2- Motor relearning:
• Passive movement to affected joint
• ES then graduated active exercise to affected muscles
• 3- Sensory relearning
• 4 -Limb protection
28. 9-SCIATIC NERVE LESION
• Clinical assessment :
• 1-Weakness or paralysis of hamstring &and all distal tibial
and peroneal nerve innervated muscles
• Functional loss of knee flexion and all ankle &toes
movement
• 2-sensory loss over the whole foot
• 3-lost knee jerk
• 4-Drop foot with high steppage gait
29. REHABILITATION OF SCIATIC
NERVE LESION
• 1- pain management:
• Heat &TENS
• Cane if there is pain during walking
• Leg elevation to increase venous return
• 2- Motor relearning:
• Passive movement to affected joint
• ES then graduated active exercise to affected muscles
• 3- Sensory reeducation
• 4 -Limb protection ankle foot orthosis
•
30. 10-COMMEN PERONEAL NERVE
LESION
• Lesion at fibular head level
• Clinical assessment :
• 1- Weakness or paralysis of toes extensors & ankle dorsiflex and
evertors
• Functional loss of ankle dorsiflexion and eversion withn toes extension
• 2-Sensory loss over dorsal foot
• 3-Normal ankle reflexes
• 4- High steppage gait
31. REHABILITATION OF SCIATIC
NERVE LESION
• 1- Pain managment:
• Heat &TENS
• 2-Motor relearning:
• Passive movement to affected joint
• ES then graduated active exercise to affected muscles
• 3- Sensory reeducation
• 4 -Limb protection ankle foot orthosis
• Avoid position that compress the nerve on fibular head
• -Sitting cross
• -Sleeping with legs externally rotated
32. 11-POSTIOR TIBIAL NERVE LESIONS
• 1-lesion at the knee level:
• Clinical assessment
• 1- Weakness or paralysis of calf muscles ,tibialis posterior and toes
flexors
• patient can not make planter flexion& inversion, and toes flexion
• 2-Sensory loss over planter and lateral foot
• 3-Loss of ankle deep reflexes
• 4-Atrophy of calf and intrinsic muscles except extensor digitorum
brevis
33. REHABILITATION OF POSTERIOR
TIBIAL NERVE LESION
• 1- Pain management:
• Heat &TENS
• 2-Motor relearning:
• Passive movement to affected joint
• ES then graduated active exercise to affected muscles
• 3- Sensory reeducation
• 4 -Limb protection
• -Cane if gait is painful
• Leg elevation if vascular return is problem
•
34. POSTERIOR TIBIAL NERVE AT
TARSAL TUNNEL
• Clinical assessment
• 1- Weakness of foot intrinsic muscles except extensor
digitorum brevis
• 2-Sensory loss over medial and or lateral planter surface
• 3-Normal ankle reflexes
• 4-Atrophy of intrinsic muscles except extensor digitorum
brevis
35. REHABILITATION OF
POSTERIOR TIBIAL NERVE
• 1- Pain management:
• Heat &TENS
• 2-Motor relearning:
• Passive movement to toes
• Mobilization of tarsal and metatarsal bones
• Strengthening exercise to affected muscles
• 3- Sensory reeducation : in desensitized areas
• 4 -Limb protection:
• -Avoid wearing shoes that compress medial aspect of foot and ankle