Path physiology of Tissue

1. Royal Metropolitan
University.
M.Ibrahim.Raza.
SEM-4
GM-5
PATH-PHYSIOLOGY

2. Path-Physiology of Tissue
Growth

3. General characteristics of Main
types of violation tissue growth.
• There diseases are classified as hypo-biotic
and hyper-biotic diseases. Upon these they
are further classified as :
• Atrophy
• Hypo-plasia
• Hypertrophy
• Hyperplasia

4. Further….
• Dysplasia
• Regeneration
• Tumor
• So, basically a TUMOR formation
is basically the result of one the
above mentioned processes as
depending upon the specific
origin and organ.

5. GENERAL RESPONSE.

6. Etiology
• Etiological factors of tumors includes :
• Chemical factors
• Physical factors
• Biological blastogenic
factors
• Cocancerogens
• Syncarcerogens

7. Basic Eitiological Factors.

8. Theories of pathogenesis of Tumor
Growth.
• It includes following theories :
• Mutation theory
• Epigenomic theory
• Viral genetic theory
• Theory of endogenous
viruses
• Theory of formation of tumor
forming protovirus genes

9. Further ….
• Theory of insufficiency of DNA repair
• Theory of two-stage carcinogenesis
• Theory of Oncogenes of viral and other nature

10. Stages of Carcinogenesis

11. Principles of Diagnosis
• Diagnosis :
• Determination of nature and
cause of diseases. It includes
following :
1. Clinical history
2. Physical examination
3. Differential diagnosis

12. Moreover….
• Prognosis :
• Eventual outcome of disease.
It includes treatment :
• Specific treatment – directed at underlying
cause.
• Symptomatic treatment – alleviates
symptoms but does not influence the course
of disease.

14. Treatment of Malignant Neoplasms.
• Treatment of M.N involves :
• Biomarker testing
• Chemotherapy
• Hormone therapy
• Hyperthermia
• Immuno therapy
• Stem cell transplant

16. Refrences
• Most of the data is taken by :
1. SELF—SEARCH
2. General info
3. Nor specific articles but
the basic concepts given
by our Teacher.