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Prof. Dr Hamed Attia
Vaccination Program For Protection From Diseases
in Farm Animals
Part 1:
( Vaccination of shipping fever and clostridial diseases
1 – What is the vaccine.
2 – What is the importance of
vaccination.
3 – Type of vaccine.
4 – Difference between vaccine
&hyper-immune serum.
5 – Most important vaccine used
in new born animals
What is a vaccine
● A vaccine is defined as a preparation of
dead or weakened pathogens, or their
antigenic components which induces
protective immunity against the specific
pathogen (micro-organism, tumour,
toxin), but which does not itself cause
disease.
.
Types of Immunity
1- Passive immunity of the newborn is
obtained via the colostrum of the vaccinated or
immune mother.
2- Active Immunty
* Vaccines (like a natural infection)
induce a specific, systemic and /or local
humoral and or cell-mediated immune
response to initiate or enhance protection
of the host against a specific organism.
▪ Owners must remember that vaccines do
not provide 100 percent protection against
infections and many factors determine how
much protection is provided.
Important Notes
▪ The vaccine is designed to cause a mild
infection in the animal which leads to an
improved immune response
▪ Individual animal respond to a vaccines in
different ways due to factors such as stress,
immune status at time of vaccination.
Important Notes
▪ It is also not a good idea to vaccinate a sick
animals since the animal will not develop
as good of an immune response as well as a
healthy.
▪ These animals should be vaccinated 2-3
weeks after recovering from the illness
Important Notes
Importance of vaccines
Importance of Vaccines
Veterinary Vaccines are essential for:
1- Protection of individual animals
Herd immunity to break chains of
transmission
2- Safe and efficient food production
3- Control of emerging, re-emerging and
exotic diseases of animals and people
4-Reduction of transmission of food borne
disease.
5- Control of zoonotic diseases and thus the
threat and/or impact on human lives (e,g,
rabies, influenza, Rift Valley Fever,
brucellosis etc
6- Reduction of animal suffering
7- Reduction in the need for antibiotics or
more costly alternatives to treat animals
8- Control of diseases of companion animals
and horses
*VACCINATION PROGRAM IN
FARM ANIMAL
*TYPES OF VACCINE USED
INFECTIOUS VACCINES
(ANTIGENS)
◼ TYPES:
– 1-modified live vaccines; ‫المضعفة‬ ‫الحية‬ ‫اللقاحات‬
– intramuscular, subcutaneous, intranasal
IMMUNITY DURATION
– life-time (infection established, cellular and
humoral immunity)
– one dose required
– annual boosters may not be required
2-NON-INFECTIOUS VACCINES
(ANTIGENS)
◼ TYPES: ‫الميتة‬ ‫اللقاحات‬
– killed vaccines and bacterins – intramuscular,
subcutaneous
– toxoids and leukotoxoids – intramuscular,
subcutaneous
◼ IMMUNITY DURATION:
– 4 to 12 months (infection not
established, humoral immunity)
– primary dose required (priming)
– secondary dose required – 3 to 6 weeks
later (within 4 months)
– Annual or semiannual boosters required
1-Bacterial Vaccine
1- Pasteurellosis Vaccine
Inactivated HS Oil Adjuvant
Vaccine (type B:6)
PACKAGE:
bottle 300 ml. (150 dose).
Protection of cattle & sheep
against HS & pneumonic
pasteurellosis
2 ml in cattle
1 ml in sheep
IM
9 m
1
Inactivated Oil Adjuvant
Polyvalent Pneumonic
Pasteurellosis Vaccine
Cattle and buffaloes:
Over 100kg 2ml
Under 100kg 1ml.
Sheep & goat : 1ml.
PACKAGE: bottles 300 ml. (150 dose for cattle, 300 dose for sheep & goat).
Protection of Cattle, Sheep & Goat
against pneumonic pasteurellosis.
2nd dose 4 weeks apart
One year
IM
2
Imported Vaccine
◼ Pasterovis
PASTEROVIS®
is a vaccine for the
medical preventions of
the primary or
secondaries pasteurella
infections due to
Pasteurella multocida
and Pasteurella
haemolytica
2- Colosterdia Vaccine
Antibody titers
Antibody titers that peaked at day 36 after vaccination
and large inter individual variations in the magnitude of
the response.
Antibody titers were maintained up to 90 days and then
markedly decreased, becoming even undetectable in
some animals 6 months after vaccination
Antibody titers peak
Antibody titers that peaked at day 36 after vaccination
and large inter individual variations in the magnitude of
the response.
Antibody titers were maintained up to 90 days and then
markedly decreased, becoming even undetectable in
some animals 6 months after vaccination
Covexin 10
COGLAVAX®
(Clostridiosis): It is a
vaccine that contains 8
different clostridial
antigens in one single
dose. Clostridial
pathogens are ubiquitious
and cattle are at risk to be
hit by these diseases
during most of their lives.
Unique pasteurella and clostridial
combination vaccine
Bar-Vac®
Unique pasteurella and clostridial combination vaccine
offering protection against pneumonic pasteurollosis and
most common clostridial diseases

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Parte 1 vaccination program in farm animals

  • 1. Prof. Dr Hamed Attia Vaccination Program For Protection From Diseases in Farm Animals Part 1: ( Vaccination of shipping fever and clostridial diseases
  • 2. 1 – What is the vaccine. 2 – What is the importance of vaccination. 3 – Type of vaccine. 4 – Difference between vaccine &hyper-immune serum. 5 – Most important vaccine used in new born animals
  • 3. What is a vaccine ● A vaccine is defined as a preparation of dead or weakened pathogens, or their antigenic components which induces protective immunity against the specific pathogen (micro-organism, tumour, toxin), but which does not itself cause disease. .
  • 4. Types of Immunity 1- Passive immunity of the newborn is obtained via the colostrum of the vaccinated or immune mother.
  • 5. 2- Active Immunty * Vaccines (like a natural infection) induce a specific, systemic and /or local humoral and or cell-mediated immune response to initiate or enhance protection of the host against a specific organism.
  • 6. ▪ Owners must remember that vaccines do not provide 100 percent protection against infections and many factors determine how much protection is provided. Important Notes
  • 7. ▪ The vaccine is designed to cause a mild infection in the animal which leads to an improved immune response ▪ Individual animal respond to a vaccines in different ways due to factors such as stress, immune status at time of vaccination. Important Notes
  • 8. ▪ It is also not a good idea to vaccinate a sick animals since the animal will not develop as good of an immune response as well as a healthy. ▪ These animals should be vaccinated 2-3 weeks after recovering from the illness Important Notes
  • 10. Importance of Vaccines Veterinary Vaccines are essential for: 1- Protection of individual animals Herd immunity to break chains of transmission 2- Safe and efficient food production 3- Control of emerging, re-emerging and exotic diseases of animals and people 4-Reduction of transmission of food borne disease.
  • 11. 5- Control of zoonotic diseases and thus the threat and/or impact on human lives (e,g, rabies, influenza, Rift Valley Fever, brucellosis etc 6- Reduction of animal suffering 7- Reduction in the need for antibiotics or more costly alternatives to treat animals 8- Control of diseases of companion animals and horses
  • 12.
  • 13. *VACCINATION PROGRAM IN FARM ANIMAL *TYPES OF VACCINE USED
  • 14. INFECTIOUS VACCINES (ANTIGENS) ◼ TYPES: – 1-modified live vaccines; ‫المضعفة‬ ‫الحية‬ ‫اللقاحات‬ – intramuscular, subcutaneous, intranasal
  • 15. IMMUNITY DURATION – life-time (infection established, cellular and humoral immunity) – one dose required – annual boosters may not be required
  • 16. 2-NON-INFECTIOUS VACCINES (ANTIGENS) ◼ TYPES: ‫الميتة‬ ‫اللقاحات‬ – killed vaccines and bacterins – intramuscular, subcutaneous – toxoids and leukotoxoids – intramuscular, subcutaneous
  • 17. ◼ IMMUNITY DURATION: – 4 to 12 months (infection not established, humoral immunity) – primary dose required (priming) – secondary dose required – 3 to 6 weeks later (within 4 months) – Annual or semiannual boosters required
  • 18.
  • 21. Inactivated HS Oil Adjuvant Vaccine (type B:6) PACKAGE: bottle 300 ml. (150 dose). Protection of cattle & sheep against HS & pneumonic pasteurellosis 2 ml in cattle 1 ml in sheep IM 9 m 1
  • 22. Inactivated Oil Adjuvant Polyvalent Pneumonic Pasteurellosis Vaccine Cattle and buffaloes: Over 100kg 2ml Under 100kg 1ml. Sheep & goat : 1ml. PACKAGE: bottles 300 ml. (150 dose for cattle, 300 dose for sheep & goat). Protection of Cattle, Sheep & Goat against pneumonic pasteurellosis. 2nd dose 4 weeks apart One year IM 2
  • 24. PASTEROVIS® is a vaccine for the medical preventions of the primary or secondaries pasteurella infections due to Pasteurella multocida and Pasteurella haemolytica
  • 26.
  • 27. Antibody titers Antibody titers that peaked at day 36 after vaccination and large inter individual variations in the magnitude of the response. Antibody titers were maintained up to 90 days and then markedly decreased, becoming even undetectable in some animals 6 months after vaccination
  • 28. Antibody titers peak Antibody titers that peaked at day 36 after vaccination and large inter individual variations in the magnitude of the response. Antibody titers were maintained up to 90 days and then markedly decreased, becoming even undetectable in some animals 6 months after vaccination
  • 30. COGLAVAX® (Clostridiosis): It is a vaccine that contains 8 different clostridial antigens in one single dose. Clostridial pathogens are ubiquitious and cattle are at risk to be hit by these diseases during most of their lives.
  • 31. Unique pasteurella and clostridial combination vaccine Bar-Vac® Unique pasteurella and clostridial combination vaccine offering protection against pneumonic pasteurollosis and most common clostridial diseases