This document is a program for the 3rd annual ADC Summit 2014 conference on antibody-drug conjugates taking place from May 19-21, 2014 in London. The conference will feature presentations from industry experts on topics related to developing antibody-drug conjugates, including payloads, linkers, manufacturing, and clinical trials. Attendees can learn about the latest developments and network with other professionals in the field. A pre-conference workshop on May 21st will focus on early phase development considerations for antibody-drug conjugates to support first-in-human clinical trials.
The only event in Asia bringing global oligonucleotide and peptide leaders together to discuss current strategies and trends to accelerate promising molecules from research to commercialization.
This 3-day event is the meeting place for international and domestic scientists to share case studies and project updates, showcase new techniques and form collaborations that pave the way towards the future of China’s biopharmaceutical industry.
An ever-evolving regulatory environment makes navigating gene therapy products through to clinic much more complicated than a traditional biologic. While manufacturing platforms and regulatory requirements for testing of antibodies has existed for decades, gene therapy platforms and their testing requirements are changing rapidly with the progression of products toward commercialization.
The only event in Asia bringing global oligonucleotide and peptide leaders together to discuss current strategies and trends to accelerate promising molecules from research to commercialization.
This 3-day event is the meeting place for international and domestic scientists to share case studies and project updates, showcase new techniques and form collaborations that pave the way towards the future of China’s biopharmaceutical industry.
An ever-evolving regulatory environment makes navigating gene therapy products through to clinic much more complicated than a traditional biologic. While manufacturing platforms and regulatory requirements for testing of antibodies has existed for decades, gene therapy platforms and their testing requirements are changing rapidly with the progression of products toward commercialization.
Biopharma Production and Development China 2015 Rita Barry
As the BioPharma industry grows in China and the Asian region, we invite you to be a part of this tremendous growth & development opportunities!
IBC’s Biopharma Development & Production Week in China is THE meeting place for biopharma industry professionals and scientists to get the highest quality and practical information that will enable them to develop competitive advantages and advance their capabilities in developing and manufacturing cell lines, biosimilars, biobetters, vaccines or novel biologics.
Top Reasons Why You Should Participate:
- Establish Business Partnerships with Chinese/Asian drug developers and contract
manufacturers
- Learn technical & practical know how from experiences on the ground in Asia
- Showcase your cutting edge solutions in front of key China/Asian Biopharma
decision makers
http://www.biopharmaproduction.com
After the success of the previous edition - Bioprocessing of Advanced Cellular Therapies Congress 2016, MarketsandMarkets is pleased to announce the 2nd Annual Bioprocessing of Advanced Cellular Therapies Congress in London, UK.
Research Organizations and Pharma companies have been investing big time into the promise of cellular therapies and all signs point to the need to accelerate the process of moving from lab to patient using advanced manufacturing processes and solutions to commercialization.
With this objective, making the shift from manual processes to automation, bridging the gap between research lab and market place, and using novel and advanced technologies will be the key aspects for manufacturers to answer the challenge of scale-out.
The 2nd Annual Bioprocessing of Advanced Cellular Therapies Congress taking place on the 8th and 9th June, 2017 in London, UK focuses on this holistic approach by discussing the next generation bioprocessing, strategies, technologies and solutions to work together for this constantly evolving field.
Excipients selection for high risk formulations Smita RajputMerck Life Sciences
Are you choosing the right excipients for your high risk application? Find out how to select the right excipients and enable your process optimization to improve the total cost of ownership.
In this webinar, you will learn:
• Selection of right excipients for high risk formulation is very critical step
• Low Endotoxin and low bioburden limits are important aspect while selecting raw materials
• Strong regulatory support is crucial for high risk formulation
Excipients selection for high risk formulations like parenteral and ophthalmic applications is very challenging. Excipients should be inert with high purity for such dosage forms because trace amounts of impurities present in excipients can interact with active pharmaceutical ingredient (API) which results in instability of the formulation. This presentation discusses how to select the right excipients for high-risk applications and gives guidance for process optimization by choosing the best combination of filters and excipients to improve the total cost of ownership.
For an unparalleled experience throughout the life cycle of your therapy, BioReliance® world-class biosafety solutions offer a full range of GMP cell banking services, cell line and virus bank characterization, viral clearance and lot release testing. Merck’s complete biosafety testing solutions, paired with our long-standing reputation for quality and expertise, will give you the mission-critical capabilities to bring safe, life-changing medicines to market.
Viral Risk Mitigation - A Global Regulatory PerspectiveMilliporeSigma
Looking for insights into current global regulatory expectations for viral safety? Read the special report from BioProcess International, in collaboration with Martin Wisher, Senior Regulatory Consultant focusing on BioReliance biosafety® services.
In this webinar, you will learn:
Sources of endotoxin contamination
Contamination control strategy
Endotoxin removal strategies
Detailed description:
Endotoxin, a lipopolysaccharide (LPS), is a type of pyrogen and is a component of the exterior cell wall of Gram-negative bacteria. To ensure safety on patient’s endotoxin content in the drug should always be controlled. In a biological processing it may emanate from facility, utility, raw materials, process, and personnel. In this webinar we discuss the regulatory norms, strategies for prevention & removal of endotoxin to ensure that the final drug product is safe.
Welcome to the M Lab™ Collaboration Centers – where customers can use non-GMP lab spaces to operate equipment, evaluate processes and receive real-time technical support without disrupting production.
Plan your visit: www.merckmillipore.com/mlab
Welcome to the M Lab™ Collaboration Centers – where customers can use non-GMP lab spaces to operate equipment, evaluate processes and receive real-time technical support without disrupting production.
Plan your visit: www.merckmillipore.com/mlab
Dos Viviendas unifamiliares en el Ensanche de Barajas, junto al Ifema, campo de golf la Hinojosa y la ciudad deportiva del Real Madrid Vladebebas.
Acabadoas espectaculares!!!
Si quieres visitarla no dudes en ponerte en contacto con nosotros
Biopharma Production and Development China 2015 Rita Barry
As the BioPharma industry grows in China and the Asian region, we invite you to be a part of this tremendous growth & development opportunities!
IBC’s Biopharma Development & Production Week in China is THE meeting place for biopharma industry professionals and scientists to get the highest quality and practical information that will enable them to develop competitive advantages and advance their capabilities in developing and manufacturing cell lines, biosimilars, biobetters, vaccines or novel biologics.
Top Reasons Why You Should Participate:
- Establish Business Partnerships with Chinese/Asian drug developers and contract
manufacturers
- Learn technical & practical know how from experiences on the ground in Asia
- Showcase your cutting edge solutions in front of key China/Asian Biopharma
decision makers
http://www.biopharmaproduction.com
After the success of the previous edition - Bioprocessing of Advanced Cellular Therapies Congress 2016, MarketsandMarkets is pleased to announce the 2nd Annual Bioprocessing of Advanced Cellular Therapies Congress in London, UK.
Research Organizations and Pharma companies have been investing big time into the promise of cellular therapies and all signs point to the need to accelerate the process of moving from lab to patient using advanced manufacturing processes and solutions to commercialization.
With this objective, making the shift from manual processes to automation, bridging the gap between research lab and market place, and using novel and advanced technologies will be the key aspects for manufacturers to answer the challenge of scale-out.
The 2nd Annual Bioprocessing of Advanced Cellular Therapies Congress taking place on the 8th and 9th June, 2017 in London, UK focuses on this holistic approach by discussing the next generation bioprocessing, strategies, technologies and solutions to work together for this constantly evolving field.
Excipients selection for high risk formulations Smita RajputMerck Life Sciences
Are you choosing the right excipients for your high risk application? Find out how to select the right excipients and enable your process optimization to improve the total cost of ownership.
In this webinar, you will learn:
• Selection of right excipients for high risk formulation is very critical step
• Low Endotoxin and low bioburden limits are important aspect while selecting raw materials
• Strong regulatory support is crucial for high risk formulation
Excipients selection for high risk formulations like parenteral and ophthalmic applications is very challenging. Excipients should be inert with high purity for such dosage forms because trace amounts of impurities present in excipients can interact with active pharmaceutical ingredient (API) which results in instability of the formulation. This presentation discusses how to select the right excipients for high-risk applications and gives guidance for process optimization by choosing the best combination of filters and excipients to improve the total cost of ownership.
For an unparalleled experience throughout the life cycle of your therapy, BioReliance® world-class biosafety solutions offer a full range of GMP cell banking services, cell line and virus bank characterization, viral clearance and lot release testing. Merck’s complete biosafety testing solutions, paired with our long-standing reputation for quality and expertise, will give you the mission-critical capabilities to bring safe, life-changing medicines to market.
Viral Risk Mitigation - A Global Regulatory PerspectiveMilliporeSigma
Looking for insights into current global regulatory expectations for viral safety? Read the special report from BioProcess International, in collaboration with Martin Wisher, Senior Regulatory Consultant focusing on BioReliance biosafety® services.
In this webinar, you will learn:
Sources of endotoxin contamination
Contamination control strategy
Endotoxin removal strategies
Detailed description:
Endotoxin, a lipopolysaccharide (LPS), is a type of pyrogen and is a component of the exterior cell wall of Gram-negative bacteria. To ensure safety on patient’s endotoxin content in the drug should always be controlled. In a biological processing it may emanate from facility, utility, raw materials, process, and personnel. In this webinar we discuss the regulatory norms, strategies for prevention & removal of endotoxin to ensure that the final drug product is safe.
Welcome to the M Lab™ Collaboration Centers – where customers can use non-GMP lab spaces to operate equipment, evaluate processes and receive real-time technical support without disrupting production.
Plan your visit: www.merckmillipore.com/mlab
Welcome to the M Lab™ Collaboration Centers – where customers can use non-GMP lab spaces to operate equipment, evaluate processes and receive real-time technical support without disrupting production.
Plan your visit: www.merckmillipore.com/mlab
Dos Viviendas unifamiliares en el Ensanche de Barajas, junto al Ifema, campo de golf la Hinojosa y la ciudad deportiva del Real Madrid Vladebebas.
Acabadoas espectaculares!!!
Si quieres visitarla no dudes en ponerte en contacto con nosotros
Pegs Europe 2015 Protein & Antibody Engineering SummitNicole Proulx
PEGS Europe is the largest European event covering all aspects of protein and antibody engineering. With three consecutive years of 35% growth in attendance, and another year of expanded program coverage, this year’s event will feature:
700 attendees
175 technical presentations
125 scientific posters
Dedicated networking opportunities
Exclusive exhibit & poster viewing hours
Interactive roundtable, breakout & panel discussions
SMi is proud to present the 2017 19th annual Superbugs & Superdrugs conference, taking place on 20th and 21st March in Central London.
Expanding horizons on the growing threat of anti-microbial resistance for almost two decades, the flagship show in the global Superbugs portfolio of events will once again play host to an international audience of scientific leaders, funding bodies and drug discovery specialists, providing a focal point to push industry collaboration through updates on clinical advancements and investment opportunities.
World ADC Frankfurt 2015 - sample brochureWorld ADC
The World ADC Frankfurt meeting has been established with the simple mission of speeding up the development of more potent and safe antibody drug conjugates.
Learn not only how to make an ADC, but how to make a great one. With insights on numerous novel payload technologies, robust strategies for preclinical evaluation and emerging clinical data, there is no better opportunity to accelerate your research.
The Art Pastor's Guide to Sabbath | Steve ThomasonSteve Thomason
What is the purpose of the Sabbath Law in the Torah. It is interesting to compare how the context of the law shifts from Exodus to Deuteronomy. Who gets to rest, and why?
This is a presentation by Dada Robert in a Your Skill Boost masterclass organised by the Excellence Foundation for South Sudan (EFSS) on Saturday, the 25th and Sunday, the 26th of May 2024.
He discussed the concept of quality improvement, emphasizing its applicability to various aspects of life, including personal, project, and program improvements. He defined quality as doing the right thing at the right time in the right way to achieve the best possible results and discussed the concept of the "gap" between what we know and what we do, and how this gap represents the areas we need to improve. He explained the scientific approach to quality improvement, which involves systematic performance analysis, testing and learning, and implementing change ideas. He also highlighted the importance of client focus and a team approach to quality improvement.
The Indian economy is classified into different sectors to simplify the analysis and understanding of economic activities. For Class 10, it's essential to grasp the sectors of the Indian economy, understand their characteristics, and recognize their importance. This guide will provide detailed notes on the Sectors of the Indian Economy Class 10, using specific long-tail keywords to enhance comprehension.
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This presentation provides a briefing on how to upload submissions and documents in Google Classroom. It was prepared as part of an orientation for new Sainik School in-service teacher trainees. As a training officer, my goal is to ensure that you are comfortable and proficient with this essential tool for managing assignments and fostering student engagement.
How to Split Bills in the Odoo 17 POS ModuleCeline George
Bills have a main role in point of sale procedure. It will help to track sales, handling payments and giving receipts to customers. Bill splitting also has an important role in POS. For example, If some friends come together for dinner and if they want to divide the bill then it is possible by POS bill splitting. This slide will show how to split bills in odoo 17 POS.
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“Good insight into industry knowledge and needs”
SMi Presents the 3rd annual…
ADC Summit 2014
Making your smart bomb smarter
– creating innovative antibody-drug conjugates
Holiday Inn Regents Park Hotel, London, UK
19TH - 20TH
MAY
2014
Conference Chairs
Dr Mahendra Deonarain,
Chief Scientific Officer,
Photobiotics
Dr Adeela Kamal,
Associate Director, R&D,
Oncology Research,
MedImmune
Key Speakers Include:
• Philip Howard, PhD, Chief Scientific Officer, Spirogen Limited
• Dr Trevor Hallam, Chief Scientific Officer, Sutro Biopharma
• Dr Ronald Elgersma, Project Leader, Antibody-Drug Conjugates,
Synthon
• Dr Erica Hong, Scientist, ImmunoGen
• Dr Hagop Youssoufian, Executive Vice President of R&D, Progenics
• Dr Pamela Trail, Vice President Oncology, Regeneron
• And many more!
Benefits of attending:
• Hear cutting edge presentations and key case studies from
leading ADCs experts
• Network and learn from industry and academic opinion leaders
• Learn about latest developments pertaining to the components of
ADCs (payload, antibody and linker)
• Discover what is happening with next generation ADCs
PLUS INTERACTIVE HALF-DAY POST-CONFERENCE WORKSHOP
Wednesday 21st May 2014, Holiday Inn Regents Park Hotel, London, UK
Early phase development considerations for ADCs: Expectations for a first-in-man
Workshop leaders: Dr Gavin Edwards, Manager, PAREXEL Consulting
Dr Amanda Suitters, Principal Consultant, PAREXEL Consulting
8.30am - 5.00pm
Sponsored by
www.adcsummit.com
BOOK BY 28TH FEBRUARY AND RECEIVE A £300 DISCOUNT OR BOOK BY 31ST MARCH AND RECEIVE A £100 DISCOUNT
Register online or fax your registration to +44 (0) 870 9090 712 or call +44 (0) 870 9090 711
2. ADC Summit 2014
Day One | Monday 19th May 2014
8.30
Registration & Coffee
9.00
Chairman's Opening Remarks
Dr Mahendra Deonarain, Chief Scientific Officer, Photobiotics
1.30
NANOTECHNOLGY
9.10
OPENING ADDRESS
The development of nanobodies and their potential use for
ADC
• An update on the nanobody platform
• Discussing the advantages for ADC
Dr Antonin de Fougerolles, Chief Scientific Officer, Ablynx
Antibody fragment ADCs
• Use of engineered single-chain Fvs
• Light-activated and other payloads
• Comparison with whole antibodies
Dr Mahendra Deonarain, Chief Scientific Officer, Photobiotics
PRE-CLINICAL DEVELOPMENT
10.30
Exploring nano-delivery systems for antibody delivery
• Learning about the emerging applications of
nanotechnologies in ADC.
• Understanding how nanotechnology is at the leading edge
of cancer drug delivery due to its emerging features of:
- controlled release
- antibody-driven specificity
Professor Katherine Vallis, Professor of Experimental
Radiotherapeutics, University of Oxford
Creating effective strategies to reduce toxicity
• Utilizing novel linkers and payloads to improve therapeutic
index
• Examining ways to overcome the resistance developed in
clinical ADCs
• Using site specific antibody modifications to improve efficacy
Dr John Flygare, Project Leader, Discovery Chemistry,
Genentech
2.50
PSMA ADC in prostate cancer: PK/PD analysis from a phase 1
clinical trial
• Introducing novel paradigms to assess the therapeutic
efficacy in prostate cancer
• Implementing population-based model of longitudinal PSA
measurement from phase I clinical trial
• Correlation of exposure and therapeutic effect
Dr Hagop Youssoufian, Executive Vice President of R&D,
Progenics
3.30
Afternoon Tea
3.50
Development of second generation duocarmycin ADCs with
superior therapeutic window
• Developing duocarmycin based linker-drug technology
• Conducting preclinical evaluation with in vitro and in vivo
studies
Dr Ronald Elgersma, Project Leader, Antibody-Drug
Conjugates, Synthon
4.30
9.50
2.10
Let’s have a debate! Discussing creative ways to make
the ‘smart bomb’ more intelligent when building your
oncology arsenal
• Discussing latest challenges and improvements to various
pieces of the of ADC technology puzzle pertaining to:
- Antibodies
- Drugs
- Linkers that bond them together
Philip Howard, PhD, Chief Scientific Officer, Spirogen Limited
Morning Coffee
10.50
Producing Better Antibody-Drug Conjugates (ADCs) Using
ThioBridge™ Conjugation
• Site-specific conjugation to disulfide bonds of antibodies
and antibody fragments reduces ADC heterogeneity
• ThioBridge™ linkers provide stable conjugates and can be
used with a variety of payloads
• ThioBridge™ technology can be used to create novel ADC
formats
• In vitro and in vivo data demonstrates good efficacy for
mAb and Fab conjugates with an established payload
George Badescu, PhD, Director of Scientific Affairs Bioconjugation & Protein Engineering, PolyTherics Ltd, UK
11.30
Working in perfect harmony - selecting the right target and
the right antibody
• Understanding lessons learned from target identification
and validation
• Realizing the importance of target expression and
internalization
• Reviewing approaches to select a lead ADC: a case study
Dr Adeela Kamal, Associate Director, R&D, Oncology
Research, MedImmune
12.10
Networking Lunch
ROUNDTABLE
MANUFACTURING ADCs
5.10
Chairman's Closing Remarks and Close of Day One
Sponsored by
SPONSORSHIP AND EXHIBITION OPPORTUNITIES
PolyTherics offers proprietary site-specific ThioBridge™
conjugation technology for creation of antibodydrug conjugates with greater stability and reduced
heterogeneity as well as site-specific conjugation
technologies for pegylation. In addition, through
recent acquisition, Antitope provides proprietary
technologies
for
preclinical
prediction
of
immunogenicity, and for the generation of nonimmungenic humanized antibodies. To date, we
have entered into multiple agreements with
pharmaceutical and biotechnology companies.
www.polytherics.com
SMi offer sponsorship, exhibition, advertising and branding
packages, uniquely tailored to complement your company’s
marketing strategy. Prime networking opportunities exist to
entertain, enhance and expand your client base within the
context of an independent discussion specific to your industry.
Should you wish to join the increasing number of companies
benefiting from sponsoring our conferences please call:
Alia Malick on +44 (0) 20 7827 6168 or
email: amalick@smi-online.co.uk
Want to know how you can get involved?
Interested in promoting your services to this market?
Contact Teri Arri, SMi Marketing on +44 (0) 207 827 6162,
or email: tarri@smi-online.co.uk
Register online at: www.adcsummit.com • Alternatively fax you
3. Day Two | Tuesday 20th May 2014
8.30
Registration & Coffee
9.00
2.10
Chairman's Opening Remarks
Dr Adeela Kamal, Associate Director, R&D, Oncology
Research, MedImmune
NEXT GENERATION ADCs
9.10
OPENING ADDRESS
The development of the pyrrolobenzodiazepine ADC platform
• Introduction to the pyrrolobenzodiazepine antitumor
antibiotics
• Pyrrolobenzodiazepine antibody conjugates
• Development of synthetic pyrrolobenzodiazepines
Philip Howard, PhD, Chief Scientific Officer, Spirogen Limited
9.50
Addressing tumor heterogeneity and resistance: production
of homogeneous bispecific ADCs with combination warheads
• Cell–free protein synthesis methods have been developed
for production of homogeneous therapeutic proteins,
including ADCs
• Many variants can be expressed in hours and rapidly
assessed for function. Within days, production of chosen
variants can be scaled using the same platform to
generate material for clinical studies.
• The power and utility of the platform to design and
manufacture single species bispecific and multispecific
antigen-targeted antibodies with conjugated combination
warheads will be described
Dr Trevor Hallam, Chief Scientific Officer, Sutro Biopharma
2.50
Realizing the importance of occupational health and safety
in ADC projects
• Examining biopharmaceutical compound hazards –
biological, small molecule and others
• ADC facility design elements; facilities, layouts and
equipment
• Occupational hygiene analytical (bio)chemistry
• Building confidence that the working environment is safe
and that containment equipment is working
Justin Mason-Home, Managing Director, SafeBridge Europe,
Limited
3.30
Afternoon Tea
Morning Coffee
10.50
SAFETY AND DESIGN
Fleximer-based ADCs: Overcoming common hurdles
• Improving DAR without sacrificing PK and tolerability
• Maximizing efficacy of ADCs targeting low expression
targets
• Broadening the diversity of payloads amenable to ADCs
Dr Tim Lowinger, Chief Scientific Officer, Mersana
10.30
11.30
Targeted Thorium Conjugate Platform
• Targeted delivery
• Cancer
• Alpha emitter
• Preclinical in vitro and in vivo models
Dr Andreas Menrad, Chief Scientific Officer, Algeta
12.10
Arming disease-targeting antibodies with cytotoxic drugs
and with cytokines
• Antibody-cytokine fusions: From the bench to the clinic
• Cancer cures with non-internalising antibodies
• Applications of armed antibodies beyond oncology
Dr Giulio Casi, Head of Antibody-Drug Conjugates
Development, Philochem
PAYLOAD, LINKER & TRAFFICKING STRATEGIES
3.50
Implementing strategies to ensure successful linker selections
for ADCs
• Analysing the selection criteria for choosing the right linker
technology for ADCs
• Exploring the development of linkers that show improved
activity
• Utilizing novel linker molecules
Dr Erica Hong, Scientist, ImmunoGen
4.30
Programming the GPS system for maximum target strikes!
Evaluating latest approaches for trafficking and binding to
the antigen
• Discussing formats that can assess ADC trafficking from the
perspective of:
- Screening
- Mechanistic
• Assessing intracellular trafficking, internalization, and
metabolism of the parent antibody
• Understanding how trafficking processes should allow the
use of more stable linkers, which are generally less toxic
Nathan Scott, Principal Scientist, Biotherapeutic Discovery &
Engineering, Global Biotherapeutic Technologies, Pfizer
5.10
Chairman’s Closing Remarks and Close of Day Two
Networking Lunch
1.30
Official Media Partners
Design and development of effective ADCs: putting the
pieces together
• Target selection: tumor versus normal tissue expression,
when is enough enough?
• Selection of antibodies optimized for use in ADCs
• Linker selection: ADC internalization and intracellular
trafficking
• Drug selection: potency and mechanism of action of
antibody-targeted drugs
Dr Pamela Trail, Vice President Oncology, Regeneron
Supported by
ur registration to +44 (0)870 9090 712 or call +44 (0)870 9090 711
4. HALF-DAY POST-CONFERENCE WORKSHOP
Wednesday 21st May 2014
8.30am - 5.00pm
Holiday Inn Regents Park Hotel, London, UK
Early phase development considerations
for ADCs: Expectations for a first-in-man
Workshop Leaders:
Dr Gavin Edwards, Manager, PAREXEL Consulting
Dr Amanda Suitters, Principal Consultant, PAREXEL
Consulting
Overview of workshop:
The development of existing or novel monoclonal
antibodies as drug-conjugates to increase the targeted
clinical effect of these proteins has rapidly increased in
recent years. Over 30 antibody-drug conjugates (ADCs)
are being tested in the clinic in a range of oncology
indications. In the absence of specific guidance on the
development of antibody-drug conjugates. This workshop
aims to help participants understand the regulatory
requirements for the early phase of ADC development to
support first-in man clinical trials.
Why you should attend:
• Understand the CMC challenges and regulatory
expectations during early stage development of ADCs,
with a particular focus on product characterisation,
stability testing and control
• Identify key parameters/requirements for non-clinical
studies to support a Phase 1 clinical trial
• Learn how to create an early phase product
development plan that meets regulatory expectations
• Partake in Interactive case studies and group tasks that
will illustrate the points made
Programme
8.30 Registration and coffee
9.00
Welcome and Introductions
9.10
Session 1 CMC expectations applicable to early stage ADC
development (including interactive case studies)
10.30 Coffee break
11.00 Session 2 CMC expectations applicable to early stage ADC
development (including interactive case studies)
12.30 Lunch
1.30
Session 3 Nonclinical expectations/studies applicable to
early stage ADC development
3.00
Coffee Break
3.30
Session 4 Interactive case studies to evaluate nonclinical
studies to facilitate early stage ADC development
5.00
End of workshop
About the workshop hosts:
Dr Gavin Edwards, Manager, PAREXEL Consulting
Dr Edwards is a PhD Molecular and Cellular
Biologist; he earned is PhD working within the
world renowned Tyrrell Research Group based
within the Department of Pharmacy and Pharmacology,
University of Bath, UK. Following this, Dr Edwards spent time
working within the New Product Development Group of a
multi-national biologics manufacturer; here much of his
work involved the commercialisation of a CHO cell-line
capable of generating afucosyl monoclonal antibodies.
Since that time Dr Edwards has held senior posts within a
number of leading biopharmaceutical consultancies. Dr
Edwards currently serves as a Manager, PAREXEL
Consulting (UK); his consulting activities are primarily
focussed on the development and regulation of biotech
products. Dr Edwards is frequently invited to speak at
industry events and is a recognised figure within his field.
Dr Amanda Suitters, Principal Consultant,
PAREXEL Consulting
Dr Amanda Suitters is an experienced
postdoctoral research scientist/immunologist
having worked in both academia and the
biopharmaceutical industry for over twenty years and
utilizes her experience to assist biopharmaceutical and
biotechnology companies in relation to nonclinical
development, regulatory submissions, biosimilars, PIPs and
orphan drugs. She has expertise in the preparation of
nonclinical drug development documents particularly in
the field of biopharmaceutical and biosimilar
development globally. Dr Suitters assists companies in their
interactions with regulatory agencies throughout the
product development process, including Scientific Advice,
EU registration procedures & MAA submissions.
5. SMi PHARMACEUTICALS
FORWARD PLANNER 2014
JANUARY
Pharmaceutical Microbiology
20 – 21 January 2014, London
Social Media in the Pharmaceutical Industry
22 – 23 January 2014, London
Pre-Filled Syringes
27 – 28 January 2014, London
FEBRUARY
Parallel Trade
10 – 11 February 2014, London
Advances and Progress in Drug Design
17 – 18 February 2014, London
Quality By Design
24 – 25 February 2014, London
MARCH
Superbugs and Superdrugs - A Focus on
Antibacterials
5 – 6 March 2014, London
Imaging in Cancer Drug Development
12 – 13 March 2014, London
Controlled Release
12 – 13 March 2014, London
Adaptive Designs
24 – 25 March 2014, London
Paediatric Clinical Trials
31 – 1 April 2014, London
Pre-Filled Syringes USA
31 March – 1 April 2014, USA
APRIL
Asthma & COPD
2 – 3 April 2014, London
Biosimilars USA
7 – 8 April 2014, USA
MAY
Big Data in Pharma
12 – 13 May 2014, London
Pain Therapeutics
19 – 20 May 2014, London
ADC Summit
19 – 20 May 2014, London
Clinical Trial Logistics
21 – 22 May 2014, London
JUNE
Biobanking
23 – 24 June 2014, London
ADMET
30 June – 1 July 2014, London
Peptides
30 June – 1 July 2014, London
JULY
Lyophilisation
7 – 8 July 2014, London
BioNetworks
7 – 8 July 2014, London
Allergies
9 – 10 July 2014, London
Immunogenicity
14 – 15 July 2014, London
SMi offer sponsorship, exhibition, advertising and
branding packages, uniquely tailored to
complement your company's marketing strategy.
Prime networking opportunities exist to entertain,
enhance and expand your client base within the
context of an independent discussion specific to
your industry. Should you wish to join the
increasing number of companies benefiting from
sponsoring our conferences please call: Alia
Malick Sponsorship Director on +44 20 7827 6168
or email: amalick@smi-online.co.uk
6. ADC SUMMIT 2014
Conference: Monday 19th May & Tuesday 20th May 2014, Holiday Inn Regents Park Hotel, London, UK
Workshop: Wednesday 21st May 2014, London
4 WAYS TO REGISTER
www.adcsummit.com
FAX your booking form to +44 (0) 870 9090 712
PHONE on +44 (0) 870 9090 711
POST your booking form to: Events Team, SMi Group Ltd, 2nd Floor
South, Harling House, 47-51 Great Suffolk Street, London, SE1 0BS, UK
EARLY BIRD □
DISCOUNT □
Book by 28th February to receive a £300 discount off the conference price
Book by 31st March to receive a £100 discount off the conference price
CONFERENCE PRICES
Unique Reference Number
Our Reference
I would like to attend: (Please tick as appropriate)
LV P-105
DELEGATE DETAILS
Please complete fully and clearly in capital letters. Please photocopy for additional delegates.
Title:
Forename:
Fee
Total
□ Conference & Workshop
□ Conference only
□ Workshop only
£2098.00 + VAT
£2517.60
£1499.00 + VAT
£1798.80
£599.00
+ VAT
£718.80
£999.00
+ VAT
£1198.80
PROMOTIONAL LITERATURE DISTRIBUTION
□ Distribution of your company’s promotional
Surname:
Job Title:
literature to all conference attendees
Department/Division:
Company/Organisation:
The conference fee includes refreshments, lunch, conference papers and access
Email:
to the Document Portal containing all of the presentations.
Company VAT Number:
Address:
LIVE STREAMING/ON DEMAND/ DOCUMENTATION
Unable to travel, but would like to watch the conference live, ask questions,
participate as if you were in the room.
Price
Total
Town/City:
Post/Zip Code:
Country:
Direct Tel:
Direct Fax:
□ Live Streaming
□ On demand
Mobile:
(available 24 hours after the event)
□ Access to the conference documentation
Switchboard:
Signature:
Date:
I agree to be bound by SMi's Terms and Conditions of Booking.
ACCOUNTS DEPT
Title:
on the Document Portal
£499.00 + VAT
£499.00 (or only £300 if ordered with the Document Portal)
□ The Conference Presentations - paper copy
£598.80
£499.00
Forename:
Surname:
PAYMENT
Email:
Payment must be made to SMi Group Ltd, and received before the event, by one of
the following methods quoting reference P-105 and the delegate’s name. Bookings
made within 7 days of the event require payment on booking, methods of payment
are below. Please indicate method of payment:
Address (if different from above):
Town/City:
Post/Zip Code:
Country:
Direct Tel:
□ UK BACS
□ Wire Transfer
Direct Fax:
VENUE
£999.00 + VAT (UK) £1198.80
£599.00 + VAT (UK) £718.80
Holiday Inn Regents Park Hotel, Carburton Street, London W1W 5EE
England
□ Please contact me to book my hotel
Alternatively call us on +44 (0) 870 9090 711,
email: hotels@smi-online.co.uk or fax +44 (0) 870 9090 712
Terms and Conditions of Booking
Payment: If payment is not made at the time of booking, then an invoice will be issued and must be
paid immediately and prior to the start of the event. If payment has not been received then credit
card details will be requested and payment taken before entry to the event. Bookings within 7 days
of event require payment on booking. Access to the Document Portal will not be given until payment
has been received.
Substitutions/Name Changes: If you are unable to attend you may nominate, in writing, another
delegate to take your place at any time prior to the start of the event. Two or more delegates may
not ‘share’ a place at an event. Please make separate bookings for each delegate.
Cancellation: If you wish to cancel your attendance at an event and you are unable to send a
substitute, then we will refund/credit 50% of the due fee less a £50 administration charge, providing
that cancellation is made in writing and received at least 28 days prior to the start of the event.
Regretfully cancellation after this time cannot be accepted. We will however provide the
conferences documentation via the Document Portal to any delegate who has paid but is unable
to attend for any reason. Due to the interactive nature of the Briefings we are not normally able to
provide documentation in these circumstances. We cannot accept cancellations of orders placed
for Documentation or the Document Portal as these are reproduced specifically to order. If we have
to cancel the event for any reason, then we will make a full refund immediately, but disclaim any
further liability.
Alterations: It may become necessary for us to make alterations to the content, speakers, timing,
venue or date of the event compared to the advertised programme.
Data Protection: The SMi Group gathers personal data in accordance with the UK Data Protection
Act 1998 and we may use this to contact you by telephone, fax, post or email to tell you about other
products and services. Unless you tick here □ we may also share your data with third parties offering
complementary products or services. If you have any queries or want to update any of the data that
we hold then please contact our Database Manager databasemanager@smi-online.co.uk or visit
our website www.smi-online.co.uk/updates quoting the URN as detailed above your address on the
attached letter.
□ Cheque
□ Credit Card
Sort Code 300009, Account 00936418
Lloyds TSB Bank plc, 39 Threadneedle Street, London, EC2R 8AU
Swift (BIC): LOYDGB21013, Account 00936418
IBAN GB48 LOYD 3000 0900 9364 18
We can only accept Sterling cheques drawn on a UK bank.
□ Visa □ MasterCard □ American Express
All credit card payments will be subject to standard credit card charges.
□□□□ □□□□ □□□□ □□□□
Valid From □□/□□ Expiry Date □□/□□
CVV Number □□□□ 3 digit security on reverse of card, 4 digits for AMEX card
Card No:
Cardholder’s Name:
Signature:
Date:
I agree to be bound by SMi's Terms and Conditions of Booking.
Card Billing Address (If different from above):
VAT
VAT at 20% is charged on the attendance fees for all delegates. VAT is also charged on live
Streaming, on Demand, Document portal and literature distribution for all UK customers and
for those EU Customers not supplying a registration number for their own country here.
______________________________________________________________________________________________
If you have any further queries please call the Events Team on tel +44 (0) 870 9090 711 or you can email them at events@smi-online.co.uk