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psychosomatic disorders
part 3
ORAL DYSESTHESIA
Disorders related to altered oral sensation
• Burning mouth syndrome
• Idiopathic xerostomia
• Idiopathic dysgeusia
• Glossodynia
• Glossopyrosis
BURNING MOUTH SYNDROME( BMS)
• Stomatodynia.
• Patient complaint of generalised soreness or burning sensation of mouth.
• Normal appearance of oral mucosa
• Mainely tongue >> denture bearing area >> lips
• Females>>>. 7 females: 1 male
• Middle aged
• The psychological aspects of burning mouth syndrome can be
categorized into
 chronic somatoform dysfunction,
 chronic vegetative disorders,
 chronic pain phenomenon
• Burning mouth syndrome is a multifactorial disorder
associated with psychological components such as anxiety,
depression, and cancerophobia
Rule out:
• Haematinic deficiencies: vit b12, folate, iron
• Salivary gland hypofunction
• Candidiasis
• Parafunctional habits- chronic trauma
• GERD
• Depression
• Allergy to denture
• Cancerophobia
Investigations:
• Detailed history
• Detailes examination
• Blood test: CBC, serum B12, folate, RBC Folate, Serum
ferritin, blood glucose
• Quantitative assessment of candidal growth
• Salivary gland function
Confirming clinical diagnosis
Diagnostic analgesic blocking
Utilization of diagnostic drugs
Consultation
Trial therapy
• Medications that act in the brain
 Benzodiazepines,
 Tricyclic antidepressants (e.G., Amitriptyline),
 Anticonvulsants (clonazepam)
 SNRIs and SSRIs
 Respond better to low-dose combinations
• quantitative and qualitative changes in saliva
• salivary hypofunction (dry mouth).
• Depressive symptoms are usually evident.
Idiopathic xerostomia
Disturbances in taste
Dysgeusia is defined as a distorted gustatory
perception or persistent gustatory sensation in the
absence of gustatory stimulants.
Sour/metallic/bitter taste.
Middle aged females
Dysgeusia
• Quite obsessional about the condition
• Associated with Halitophobia / false halitosis
• Oral dryness irrespective of normal salivation.
• Delusional symptoms: sand/ grit in mouth, excessive
mucus discharge.
• Associated with detrimental changes in diet & lifestyle.
• It is usually associated with Candida associated
lesions (CAL), burning mouth syndrome (BMS), or
a mixed combination of CAL and BMS
Glossodynia
Glossopyrosis
• Lengthy periods of depression tend to be seen before the manifestation
of the full clinical picture of glossopyrosis.
• Lingual burning in patients with glossopyrosis is consistent with
hyperalgesia.
• neurogenic inflammation is observed in patients and animals with
magnesium deficiency and in magnesium-deficient tissues
Dental
conditions
(Periodontal
diseases
Carious lesions
Discharging dental
sinus
Marginal
restorations
Dry socket )
Associated
structures
(salivary gland
hypofunction,
sialadenitis,
sinusitis)
Systemic
diseases
(uraemia,respirator
y disease, GERD,
neurologic
disorders like
Bells’s palsy,
damage to chorda
tympani, brain
tumours)
Deficiencies
(zinc)
Drugs (ACE
inhibitors,
lithium salts,
gold,
carbimazole,
metronidazole,
penicillamine,
xerogenic drugs)
Others (
smoking)
• Zinc supplementation is believed to aid in treating
taste disorders by promoting proliferation of
normal taste bud cells, even in patients without
zinc deficiency .
• The tricyclic antidepressants such as amitriptyline
and nortryptyline are often generally helpful
• Body dysmorphic syndrom
• Delusional halitophobia
• Cancerophobia
• Phantom bite syndrome
Delusional symptoms:
Abnormal belief from which individual cannot be dissuaded
& which is not in keeping with his/ her cultural backgrounds.
“Phantom bite syndrome”
• Complains of abnormal bite / lumps under oral mucosa
• Avoid unnecessary treatment in such patients.
• “occlusal discomfort” or “occlusal dysesthesia”
• Various MUS, including headache, dizziness, shoulder
stiffness, low back pain, and fatigue, often accompany
PBS and worsen after even minor dental adjustments,
which the patients have requested
Delusional halitosis
• Form of monosymptomatic hypochondriacal psychosis
• Halitophobia is an olfactory reference syndrome
• A psychological condition that the dental surgeon is illequipped to treat alone.
• Delusional halitosis may present clinically as a spectrum ranging from an
overvalued belief to a frank delusional disorder in which the individual can
hardly be dissuaded from his or her belief of mouth odor
• The person will be presenting with false offensive mouth odor.
• Both pseudo-halitosis and halitophobia patients must be referred to
psychological specialists
• Treatment for delusional halitosis is challenging:
Type of anthrophobia.
Mainely in adolescents
• Disorder caused by altered perception of dentofacial form
and function.
• Body dysmorphic disorder (BDD) is a psychological
syndrome which results in patients seeking treatment for
an imagined defect in their appearance.
• Aesthetic dental treatment for such patients is not
beneficial and
carries some potential risks
Dysmorphophobia
• Not a phobia.
• Serious preoccupation with an aspect of their physical
appearance that they feel is defective.
• Minor problem/ imaginary.
• Acceptable or abnormal appearance are open to
subjective interpretation , but when suspect psychologic
problem seek specialist opinion.
Self injurious behaviour
• Bruxism is the parafunctional clenching and grinding
action between the upper and lower teeth
• create many dental problems, such as abfractions,
hypersensitivity, periodontal distraction, and
temporomandibular dysfunction .
Dental and periodontal diseases
caused by bruxism
• Factitious disorder/ self mutilation behaviour
• Psychologic / psychiatric disorder charecterized by
compulsive, voluntary production of signs & symptoms
of disease for sole purpose of assuming a ‘patient’s role’
and in absence of other secondary gain.
• Also seen in children who seek special attention from
family.
• May or maynot intensional.
• Physical/ developmental/ learning disabilities.
• (epilepsy/ profound neurodisability/ cerebral palsy/ autism/ lesch-Nyhan syndrome, Riley –
Day syndrome
• Trauma to lips/ cheek/ tongue.
• GINGIVITIS ARTEFACTA: often caused with finger nail.
• FACTITIOUS STOMATITIS
• DERMATITIS ARTEFACTA
LOCAL
• Topical anesthetic
• Topical antiseptic
• Suture to close wound
• Bite raising appliance
• Occlusal guards/lip bumper
• Restorations of broken teeth
• Extractions
• Occlusal adjustment to teeth
SYSTEMIC
• Analgesic & antibiotic
• Oral lichen planus
• Recurrent aphthous stomatitis
• Psoriasis
• Mucous membrane pemphigoid
• Erythema multiforme
Auto immune disorders
• Chaudhary has reported higher scores of anxiety, depression and
stress in patients with OLP in comparison to healthy controls .
• Burkhart et al. (1997) assessed medical history, lifestyle and
health habits and pointed out to the occurrence of stressful
events at the onset of OLP in 51 per cent of the subjects.
• More recently Rojo-Moreno et al. (1998) in a controlled study
on 100 patients using different psychometric tests found greater
anxiety and depression in OLP patients than the controls .
Oral lichen planus
• Factor potentially related with RAS exacerbations is
stress (Natah et al. 2004; Keenan and Spivakovksy
2013; Scully et al. 2003; Sook-Bin and Sonis 1996;
Volkov et al. 2009; Zadik et al. 2012) [34].
• Psychological stresses induces immunoregulatory
activity by increasing the number of leukocytes at
sites of inflammation; this is a characteristic often
observed during the pathogenesis of RAU
Recurrent aphthous ulcers
• Psoriasis is a papulosquamous exfoliative
dermatitis which presents as discrete flat-
topped papules or plaques covered with thin,
white, loosely adherent scales.
psoriasis
• Role of stress is evident with deregulation of T-
lymphocyte activity
Erythema multiforme
• Recurrent herpes labialis
• Necrotizing ulcerative gingivostomatitis
• Chronic periodontal diseases
Miscellaneous disorders
• In recurrent herpes labialis, Emotional stress apparently
serves to prevent the antibodies from acting at the
local mucosal site
The temporal relationship of psychosocial stress to
cellular immunity and herpes labialis recurrences.
Schmidt DD, Schmidt PM Fam Med. 1991 Nov-
Dec;23(8):594-9
• significant inverse correlations between stress level scores and
percent CD4 helper/inducer T lymphocytes in both subjects
: two individuals with positive antibodies to the herpes
simplex virus, one with recurrent herpes and one without a
history of recurrent herpes; for 32 weeks.
Mechanisms through physiologic pathways may
influence periodontal tissues :
• alteration in saliva,
• changes in gingival blood circulation,
• Endocrine imbalances and
• altered host resistance
• Depressed immunity and enhancing infection
Chronic periodontal disease
Eating disorder
• Anorexia nervosa: food avoidance, underweight,
distorted body image . Self induced vomiting.
• bulimia nervosa: binge eating, purging, normal body
weight.
• Abuse of laxatives, enemas, diuretics, exercise
• Anorexia less common than bulimia.
• Age : average 17 yrs( as early as 8 yrs
• Comorbidity with depression, social phobia, obsessive
compulsive disorder.
• Wearing of teeth.
• Parotid gland enlargement.
• Mucosal lesions, particularly in soft palate.
• Stomatitis due to nutritional/haematinic deficiencies.
• Dentist: identification/ prevention & management
Oral findings
• Biological and Biomedical Reports, 2011/2012, 1(1), 13-16 Effect of stress on oral
mucosa (PATHOPHYSIOLOGY).
• Tyldesley’s textbook on oral medicine.
• Bell’s oral and facial pain , 7th ed.
• Burket’s textbook on oral medicine. 11th ed.
• Fam Med. 1991 Nov-Dec;23(8):594-9.
• The temporal relationship of psychosocial stress to cellular immunity and herpes
labialis recurrences.
Schmidt DD1, Schmidt PM, Crabtree BF, Hyun J, Anderson P, Smith C.
REFERECES
Oral Psychosomatic Disorders part 3

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Oral Psychosomatic Disorders part 3

  • 2. ORAL DYSESTHESIA Disorders related to altered oral sensation • Burning mouth syndrome • Idiopathic xerostomia • Idiopathic dysgeusia • Glossodynia • Glossopyrosis
  • 3. BURNING MOUTH SYNDROME( BMS) • Stomatodynia. • Patient complaint of generalised soreness or burning sensation of mouth. • Normal appearance of oral mucosa • Mainely tongue >> denture bearing area >> lips • Females>>>. 7 females: 1 male • Middle aged
  • 4. • The psychological aspects of burning mouth syndrome can be categorized into  chronic somatoform dysfunction,  chronic vegetative disorders,  chronic pain phenomenon • Burning mouth syndrome is a multifactorial disorder associated with psychological components such as anxiety, depression, and cancerophobia
  • 5. Rule out: • Haematinic deficiencies: vit b12, folate, iron • Salivary gland hypofunction • Candidiasis • Parafunctional habits- chronic trauma • GERD • Depression • Allergy to denture • Cancerophobia Investigations: • Detailed history • Detailes examination • Blood test: CBC, serum B12, folate, RBC Folate, Serum ferritin, blood glucose • Quantitative assessment of candidal growth • Salivary gland function
  • 6. Confirming clinical diagnosis Diagnostic analgesic blocking Utilization of diagnostic drugs Consultation Trial therapy
  • 7. • Medications that act in the brain  Benzodiazepines,  Tricyclic antidepressants (e.G., Amitriptyline),  Anticonvulsants (clonazepam)  SNRIs and SSRIs  Respond better to low-dose combinations
  • 8. • quantitative and qualitative changes in saliva • salivary hypofunction (dry mouth). • Depressive symptoms are usually evident. Idiopathic xerostomia
  • 9. Disturbances in taste Dysgeusia is defined as a distorted gustatory perception or persistent gustatory sensation in the absence of gustatory stimulants. Sour/metallic/bitter taste. Middle aged females Dysgeusia
  • 10. • Quite obsessional about the condition • Associated with Halitophobia / false halitosis • Oral dryness irrespective of normal salivation. • Delusional symptoms: sand/ grit in mouth, excessive mucus discharge. • Associated with detrimental changes in diet & lifestyle.
  • 11. • It is usually associated with Candida associated lesions (CAL), burning mouth syndrome (BMS), or a mixed combination of CAL and BMS Glossodynia Glossopyrosis • Lengthy periods of depression tend to be seen before the manifestation of the full clinical picture of glossopyrosis. • Lingual burning in patients with glossopyrosis is consistent with hyperalgesia. • neurogenic inflammation is observed in patients and animals with magnesium deficiency and in magnesium-deficient tissues
  • 12. Dental conditions (Periodontal diseases Carious lesions Discharging dental sinus Marginal restorations Dry socket ) Associated structures (salivary gland hypofunction, sialadenitis, sinusitis) Systemic diseases (uraemia,respirator y disease, GERD, neurologic disorders like Bells’s palsy, damage to chorda tympani, brain tumours) Deficiencies (zinc) Drugs (ACE inhibitors, lithium salts, gold, carbimazole, metronidazole, penicillamine, xerogenic drugs) Others ( smoking)
  • 13. • Zinc supplementation is believed to aid in treating taste disorders by promoting proliferation of normal taste bud cells, even in patients without zinc deficiency . • The tricyclic antidepressants such as amitriptyline and nortryptyline are often generally helpful
  • 14. • Body dysmorphic syndrom • Delusional halitophobia • Cancerophobia • Phantom bite syndrome Delusional symptoms:
  • 15. Abnormal belief from which individual cannot be dissuaded & which is not in keeping with his/ her cultural backgrounds. “Phantom bite syndrome” • Complains of abnormal bite / lumps under oral mucosa • Avoid unnecessary treatment in such patients. • “occlusal discomfort” or “occlusal dysesthesia”
  • 16. • Various MUS, including headache, dizziness, shoulder stiffness, low back pain, and fatigue, often accompany PBS and worsen after even minor dental adjustments, which the patients have requested
  • 17. Delusional halitosis • Form of monosymptomatic hypochondriacal psychosis • Halitophobia is an olfactory reference syndrome • A psychological condition that the dental surgeon is illequipped to treat alone. • Delusional halitosis may present clinically as a spectrum ranging from an overvalued belief to a frank delusional disorder in which the individual can hardly be dissuaded from his or her belief of mouth odor • The person will be presenting with false offensive mouth odor. • Both pseudo-halitosis and halitophobia patients must be referred to psychological specialists
  • 18.
  • 19.
  • 20. • Treatment for delusional halitosis is challenging: Type of anthrophobia. Mainely in adolescents
  • 21. • Disorder caused by altered perception of dentofacial form and function. • Body dysmorphic disorder (BDD) is a psychological syndrome which results in patients seeking treatment for an imagined defect in their appearance. • Aesthetic dental treatment for such patients is not beneficial and carries some potential risks Dysmorphophobia
  • 22. • Not a phobia. • Serious preoccupation with an aspect of their physical appearance that they feel is defective. • Minor problem/ imaginary. • Acceptable or abnormal appearance are open to subjective interpretation , but when suspect psychologic problem seek specialist opinion.
  • 24. • Bruxism is the parafunctional clenching and grinding action between the upper and lower teeth • create many dental problems, such as abfractions, hypersensitivity, periodontal distraction, and temporomandibular dysfunction . Dental and periodontal diseases caused by bruxism
  • 25. • Factitious disorder/ self mutilation behaviour • Psychologic / psychiatric disorder charecterized by compulsive, voluntary production of signs & symptoms of disease for sole purpose of assuming a ‘patient’s role’ and in absence of other secondary gain. • Also seen in children who seek special attention from family.
  • 26. • May or maynot intensional. • Physical/ developmental/ learning disabilities. • (epilepsy/ profound neurodisability/ cerebral palsy/ autism/ lesch-Nyhan syndrome, Riley – Day syndrome • Trauma to lips/ cheek/ tongue. • GINGIVITIS ARTEFACTA: often caused with finger nail. • FACTITIOUS STOMATITIS • DERMATITIS ARTEFACTA
  • 27. LOCAL • Topical anesthetic • Topical antiseptic • Suture to close wound • Bite raising appliance • Occlusal guards/lip bumper • Restorations of broken teeth • Extractions • Occlusal adjustment to teeth SYSTEMIC • Analgesic & antibiotic
  • 28. • Oral lichen planus • Recurrent aphthous stomatitis • Psoriasis • Mucous membrane pemphigoid • Erythema multiforme Auto immune disorders
  • 29. • Chaudhary has reported higher scores of anxiety, depression and stress in patients with OLP in comparison to healthy controls . • Burkhart et al. (1997) assessed medical history, lifestyle and health habits and pointed out to the occurrence of stressful events at the onset of OLP in 51 per cent of the subjects. • More recently Rojo-Moreno et al. (1998) in a controlled study on 100 patients using different psychometric tests found greater anxiety and depression in OLP patients than the controls . Oral lichen planus
  • 30. • Factor potentially related with RAS exacerbations is stress (Natah et al. 2004; Keenan and Spivakovksy 2013; Scully et al. 2003; Sook-Bin and Sonis 1996; Volkov et al. 2009; Zadik et al. 2012) [34]. • Psychological stresses induces immunoregulatory activity by increasing the number of leukocytes at sites of inflammation; this is a characteristic often observed during the pathogenesis of RAU Recurrent aphthous ulcers
  • 31. • Psoriasis is a papulosquamous exfoliative dermatitis which presents as discrete flat- topped papules or plaques covered with thin, white, loosely adherent scales. psoriasis
  • 32.
  • 33. • Role of stress is evident with deregulation of T- lymphocyte activity Erythema multiforme
  • 34. • Recurrent herpes labialis • Necrotizing ulcerative gingivostomatitis • Chronic periodontal diseases Miscellaneous disorders
  • 35. • In recurrent herpes labialis, Emotional stress apparently serves to prevent the antibodies from acting at the local mucosal site
  • 36. The temporal relationship of psychosocial stress to cellular immunity and herpes labialis recurrences. Schmidt DD, Schmidt PM Fam Med. 1991 Nov- Dec;23(8):594-9 • significant inverse correlations between stress level scores and percent CD4 helper/inducer T lymphocytes in both subjects : two individuals with positive antibodies to the herpes simplex virus, one with recurrent herpes and one without a history of recurrent herpes; for 32 weeks.
  • 37. Mechanisms through physiologic pathways may influence periodontal tissues : • alteration in saliva, • changes in gingival blood circulation, • Endocrine imbalances and • altered host resistance • Depressed immunity and enhancing infection Chronic periodontal disease
  • 39. • Anorexia nervosa: food avoidance, underweight, distorted body image . Self induced vomiting. • bulimia nervosa: binge eating, purging, normal body weight. • Abuse of laxatives, enemas, diuretics, exercise
  • 40. • Anorexia less common than bulimia. • Age : average 17 yrs( as early as 8 yrs • Comorbidity with depression, social phobia, obsessive compulsive disorder.
  • 41. • Wearing of teeth. • Parotid gland enlargement. • Mucosal lesions, particularly in soft palate. • Stomatitis due to nutritional/haematinic deficiencies. • Dentist: identification/ prevention & management Oral findings
  • 42. • Biological and Biomedical Reports, 2011/2012, 1(1), 13-16 Effect of stress on oral mucosa (PATHOPHYSIOLOGY). • Tyldesley’s textbook on oral medicine. • Bell’s oral and facial pain , 7th ed. • Burket’s textbook on oral medicine. 11th ed. • Fam Med. 1991 Nov-Dec;23(8):594-9. • The temporal relationship of psychosocial stress to cellular immunity and herpes labialis recurrences. Schmidt DD1, Schmidt PM, Crabtree BF, Hyun J, Anderson P, Smith C. REFERECES