This document provides an overview of infections that can occur in the mandibular spaces of the head and neck region. It classifies mandibular spaces based on mode of involvement and clinical significance. It then describes in detail the anatomy, clinical features, and treatment of infections in the submental, submandibular, sublingual, masseteric, and pterygomandibular spaces. Secondary spaces that mandibular infections can spread to are also mentioned. The document aims to educate on the fascial spaces of the lower jaw and odontogenic infections that involve these spaces.